{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:00:03Z","timestamp":1780725603823,"version":"3.54.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019155","name":"Nanjing Drum Tower Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82,274,520"],"award-info":[{"award-number":["82,274,520"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008048","name":"Nanjing University","doi-asserted-by":"publisher","award":["2024AE01075"],"award-info":[{"award-number":["2024AE01075"]}],"id":[{"id":"10.13039\/501100008048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.cbi.2025.111742","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T02:24:07Z","timestamp":1757643847000},"page":"111742","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Naringenin targets and inhibits Monoamine Oxidase A\/B to bidirectionally regulate intestinal motility."],"prefix":"10.1016","volume":"421","author":[{"given":"Qi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yige","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Canwei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunzhi","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ong Shun","family":"seng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianshu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2025.111742_bib1","doi-asserted-by":"crossref","first-page":"890","DOI":"10.3390\/pharmaceutics14050890","article-title":"Optimization of naringin and naringenin extraction from Citrus \u00d7 paradisi L. using hydrolysis and excipients as adsorbent","volume":"14","author":"Stabrauskiene","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.cbi.2025.111742_bib2","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1021\/acs.jafc.3c07874","article-title":"Naringenin inhibits acid sphingomyelinase-mediated membrane raft clustering to reduce NADPH oxidase activation and vascular inflammation","volume":"72","author":"Ding","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbi.2025.111742_bib3","first-page":"1","article-title":"Tongbian formula alleviates slow transit constipation by increasing intestinal butyric acid to activate the 5-HT signaling","volume":"14","author":"Li","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2025.111742_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1296163","article-title":"Tongbian decoction restores intestinal microbiota and activates 5-hydroxytryptamine signaling: implication in slow transit constipation","volume":"14","author":"Li","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.cbi.2025.111742_bib5","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.3390\/foods13162520","article-title":"Naringenin promotes gastrointestinal motility in mice by impacting the SCF\/c-Kit pathway and Gut Microbiota","volume":"13","author":"Wu","year":"2024","journal-title":"Foods"},{"key":"10.1016\/j.cbi.2025.111742_bib6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.nutres.2023.08.006","article-title":"Biological activities of naringenin: a narrative review based on in vitro and in vivo studies","volume":"119","author":"U\u00e7ar","year":"2023","journal-title":"Nutr. Res."},{"key":"10.1016\/j.cbi.2025.111742_bib7","first-page":"649","article-title":"Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation","volume":"41","author":"Yin","year":"2017","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.cbi.2025.111742_bib8","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.3390\/ijms19103057","article-title":"Citrus aurantium L. and its flavonoids regulate TNBS-Induced inflammatory bowel disease through anti-inflammation and suppressing isolated Jejunum contraction","volume":"19","author":"He","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2025.111742_bib9","doi-asserted-by":"crossref","first-page":"14040","DOI":"10.1074\/jbc.RA118.002321","article-title":"Regulation of monoamine oxidase A (MAO-A) expression, activity, and function in IL-13-stimulated monocytes and A549 lung carcinoma cells","volume":"293","author":"Dhabal","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111742_bib10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3233\/JPD-212976","article-title":"Monoamine Oxidase-B inhibitors for the treatment of parkinson's disease: past, present, and future","volume":"12","author":"Tan","year":"2022","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.cbi.2025.111742_bib11","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.jad.2021.01.021","article-title":"Revisiting monoamine oxidase inhibitors for the treatment of depressive disorders: a systematic review and network meta-analysis","volume":"282","author":"Suchting","year":"2021","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.cbi.2025.111742_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2021.e06684","article-title":"Binding mechanism of naringenin with monoamine oxidase \u2013 b enzyme: QM\/MM and molecular dynamics perspective","volume":"7","author":"Govindasamy","year":"2021","journal-title":"Heliyon"},{"key":"10.1016\/j.cbi.2025.111742_bib13","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jep.2008.02.015","article-title":"Isolation of the MAO-inhibitor naringenin from Mentha aquatica L","volume":"117","author":"Olsen","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cbi.2025.111742_bib14","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11103-025-01567-9","article-title":"Elucidating the antioxidant potential of some flavanones as MAO-B inhibitors through DAM, in silico molecular docking and computational analysis","volume":"115","author":"Athira","year":"2025","journal-title":"Plant Mol. Biol."},{"key":"10.1016\/j.cbi.2025.111742_bib15","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1080\/1028415X.2021.1913319","article-title":"Naringenin mitigates behavioral alterations and provides neuroprotection against 3-nitropropinoic acid-induced Huntington's disease like symptoms in rats","volume":"25","author":"Salman","year":"2022","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.cbi.2025.111742_bib16","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.3390\/molecules25061299","article-title":"Antidepressant Potential of Lotus corniculatus L. subsp. corniculatus: an Ethnobotany Based approach","volume":"25","author":"Dereli","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.cbi.2025.111742_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.1046599","article-title":"Mechanistic insights into the role of plant polyphenols and their nano-formulations in the management of depression","volume":"13","author":"Kabra","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.cbi.2025.111742_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105124","article-title":"Dopamine receptors in emesis: molecular mechanisms and potential therapeutic function","volume":"161","author":"Belkacemi","year":"2020","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.cbi.2025.111742_bib19","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/apha.12229","article-title":"The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra","volume":"211","author":"Zheng","year":"2014","journal-title":"Acta Physiol."},{"key":"10.1016\/j.cbi.2025.111742_bib20","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1080\/00365521.2021.2018490","article-title":"Changes in esophagus interstitial cells of Cajal in response to acute stress","volume":"57","author":"Huang","year":"2022","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.cbi.2025.111742_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/s41586-024-08581-9","article-title":"Topological segregation of stress sensors along the gut crypt\u2013villus axis","author":"Touhara","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2025.111742_bib22","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1517\/13543784.2010.482927","article-title":"New-generation 5-HT4 receptor agonists: potential for treatment of gastrointestinal motility disorders","volume":"19","author":"Manabe","year":"2010","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.cbi.2025.111742_bib23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0161-813X(03)00113-X","article-title":"Organization of MAO A and MAO B promoters and regulation of gene expression","volume":"25","author":"Chen","year":"2004","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.cbi.2025.111742_bib24","article-title":"Rasagiline, an inhibitor of MAO-B, decreases colonic motility through elevating colonic dopamine content","volume":"30","author":"Liu","year":"2018","journal-title":"Neuro Gastroenterol. Motil."},{"key":"10.1016\/j.cbi.2025.111742_bib25","article-title":"Efficacy and safety of selegiline for the treatment of Parkinson's disease: a systematic review and meta-analysis","volume":"15","author":"Wang","year":"2023","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.cbi.2025.111742_bib26","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/cns.12727","article-title":"Adverse effects produced by different drugs used in the treatment of Parkinson's disease: a mixed treatment comparison","volume":"23","author":"Li","year":"2017","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.cbi.2025.111742_bib27","first-page":"309","article-title":"[Research progress of the dopamine system in neurological diseases]","volume":"77","author":"Niu","year":"2025","journal-title":"Sheng Li Xue Bao"},{"key":"10.1016\/j.cbi.2025.111742_bib28","doi-asserted-by":"crossref","first-page":"S179","DOI":"10.5005\/jp-journals-10071-23614","article-title":"Gastrointestinal motility disorders in critically ill","volume":"24","author":"Govil","year":"2020","journal-title":"Indian J. Crit. Care Med."},{"key":"10.1016\/j.cbi.2025.111742_bib29","doi-asserted-by":"crossref","first-page":"138","DOI":"10.14802\/jmd.22220","article-title":"Gastrointestinal dysfunction in parkinson's disease: Neuro-Gastroenterology perspectives on a multifaceted problem","volume":"16","author":"Tan","year":"2023","journal-title":"Journal of Movement Disorders"},{"key":"10.1016\/j.cbi.2025.111742_bib30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/1354750X.2022.2137235","article-title":"Naringenin modulates Cobalt activities on gut motility through mechanosensors and serotonin signalling","volume":"28","author":"Salami","year":"2023","journal-title":"Biomarkers"},{"key":"10.1016\/j.cbi.2025.111742_bib31","doi-asserted-by":"crossref","first-page":"262","DOI":"10.34172\/jhp.2022.31","article-title":"Evaluation of spasmolytic effects of naringenin on ileum contraction and intestinal charcoal meal transit: involvement of ATP-sensitive K+ channels","volume":"11","author":"Sadraei","year":"2022","journal-title":"J Herbmed Pharmacol"},{"key":"10.1016\/j.cbi.2025.111742_bib32","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1046\/j.1471-4159.2001.00154.x","article-title":"5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release","volume":"76","author":"Ichikawa","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbi.2025.111742_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41421-021-00247-4","article-title":"Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter","volume":"7","author":"Yan","year":"2021","journal-title":"Cell Discov"},{"key":"10.1016\/j.cbi.2025.111742_bib34","doi-asserted-by":"crossref","DOI":"10.1177\/1178646920964825","article-title":"The role of tryptophan and tyrosine in executive function and reward processing","volume":"13","author":"Aquili","year":"2020","journal-title":"Int. J. Tryptophan Res. : IJTR"},{"key":"10.1016\/j.cbi.2025.111742_bib35","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6668389","article-title":"Dynamical mechanisms for gene regulation mediated by two noncoding RNAs in long-term memory Formation","volume":"2021","author":"Hao","year":"2021","journal-title":"Neural Plast."},{"key":"10.1016\/j.cbi.2025.111742_bib36","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1038\/s41598-019-38910-2","article-title":"miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation","volume":"9","author":"Kozuka","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2025.111742_bib37","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.pharmthera.2006.08.004","article-title":"Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission","volume":"113","author":"Alex","year":"2006","journal-title":"Pharmacology & Therapeutics"},{"key":"10.1016\/j.cbi.2025.111742_bib38","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1038\/s12276-021-00646-3","article-title":"Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis","volume":"53","author":"Cho","year":"2021","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.cbi.2025.111742_bib39","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/s41398-023-02506-2","article-title":"Impact of genetic variants within serotonin turnover enzymes on human cerebral monoamine oxidase A in vivo","volume":"13","author":"Spies","year":"2023","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.cbi.2025.111742_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114990","article-title":"Naringenin: a flavanone with anti-inflammatory and anti-infective properties","volume":"164","author":"Cai","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.cbi.2025.111742_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2022.122231","article-title":"Anti-inflammatory effect evaluation of naringenin and its incorporation into a chitosan-based film for transdermal delivery","volume":"627","author":"Quint\u00e3o","year":"2022","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.cbi.2025.111742_bib42","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13572","article-title":"Anti-inflammatory and anticancer activities of Naringenin-loaded liquid crystalline nanoparticles in vitro","volume":"45","author":"Wadhwa","year":"2021","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.cbi.2025.111742_bib43","article-title":"Naringenin attenuates slow-transit constipation by regulating the AMPK\/mTOR\/ULK1 signalling pathway: in vivo and in vitro studies","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.cbi.2025.111742_bib44","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.3390\/nu15071647","article-title":"Constipation-Predominant Irritable Bowel Syndrome (IBS-C): effects of different nutritional patterns on intestinal dysbiosis and symptoms","volume":"15","author":"Di Rosa","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.cbi.2025.111742_bib45","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000489173","article-title":"The pathophysiology of colonic diverticulosis: inflammation versus constipation?","volume":"3","author":"Elisei","year":"2018","journal-title":"Inflamm Intest Dis"},{"key":"10.1016\/j.cbi.2025.111742_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107871","article-title":"Naringenin\/naringin therapeutic effects and the role of intestinal microflora in them","volume":"219","author":"Huang","year":"2025","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.cbi.2025.111742_bib47","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jpba.2015.10.040","article-title":"Metabolic profile of naringenin in the stomach and colon using liquid chromatography\/electrospray ionization linear ion trap quadrupole-Orbitrap-mass spectrometry (LC-ESI-LTQ-Orbitrap-MS) and LC-ESI-MS\/MS","volume":"120","author":"Orrego-Lagar\u00f3n","year":"2016","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.cbi.2025.111742_bib48","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jpba.2018.08.039","article-title":"Identification of naringin metabolites mediated by human intestinal microbes with stable isotope-labeling method and UFLC-Q-TOF-MS\/MS","volume":"161","author":"Chen","year":"2018","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.cbi.2025.111742_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1092729","article-title":"Effects of several flavonoids on human gut microbiota and its metabolism by in vitro simulated fermentation","volume":"14","author":"Pan","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.cbi.2025.111742_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.crfs.2024.100683","article-title":"Naringin ameliorates obesity via stimulating adipose thermogenesis and browning, and modulating gut microbiota in diet-induced obese mice","volume":"8","author":"Li","year":"2024","journal-title":"Curr. Res. Food Sci."},{"key":"10.1016\/j.cbi.2025.111742_bib51","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1089\/jmf.2018.0080","article-title":"Effect of daily consumption of Orange juice on the levels of blood glucose, lipids, and Gut Microbiota metabolites: Control. Clin. Trials","volume":"22","year":"2019","journal-title":"J Med Food."},{"key":"10.1016\/j.cbi.2025.111742_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156977","article-title":"Study on the effects of the Atractylodes macrocephala koidz-raphanus sativus l herb pair in alleviating senile constipation via the gut microbiota-SCFAs-5-HT axis","volume":"145","author":"Gao","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.cbi.2025.111742_bib53","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.brainres.2018.03.015","article-title":"Neurotransmitter modulation by the gut microbiota","volume":"1693","author":"Strandwitz","year":"2018","journal-title":"Brain Res."},{"key":"10.1016\/j.cbi.2025.111742_bib54","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cell.2014.11.047","article-title":"Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome","volume":"160","author":"Yan","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.cbi.2025.111742_bib55","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s004410100361","article-title":"Cellular localization of monoamine oxidase A and B in human tissues outside of the central nervous system","volume":"304","author":"Rodr\u00edguez","year":"2001","journal-title":"Cell Tissue Res."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725003722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725003722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:02:00Z","timestamp":1780722120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279725003722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":55,"alternative-id":["S0009279725003722"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111742","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Naringenin targets and inhibits Monoamine Oxidase A\/B to bidirectionally regulate intestinal motility.","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111742","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111742"}}