{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:40:59Z","timestamp":1790106059120,"version":"4.0.1"},"reference-count":107,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Korea Ministry of Education","doi-asserted-by":"publisher","award":["2022R1A6C101A739"],"award-info":[{"award-number":["2022R1A6C101A739"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["-2022R1A2B5B01001209"],"award-info":[{"award-number":["-2022R1A2B5B01001209"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003716","name":"Korea Basic Science Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003716","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.cbi.2025.111847","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:43:24Z","timestamp":1764290604000},"page":"111847","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Critical interplay between PAF receptor and PKC\u03b4 is involved in dopaminergic insult evoked by methamphetamine in mice"],"prefix":"10.1016","volume":"424","author":[{"given":"Quynh Dieu","family":"Trinh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hoon","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0036-9943","authenticated-orcid":false,"given":"Naveen","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen Nhi Doan","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hoon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duc Toan","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8284-8864","authenticated-orcid":false,"given":"Hoang-Yen Phi","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5684-1165","authenticated-orcid":false,"given":"Duy-Khanh","family":"Dang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Joong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Hun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitaka","family":"Nabeshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0420-795X","authenticated-orcid":false,"given":"Hyoung-Chun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7411-5420","authenticated-orcid":false,"given":"Eun-Joo","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2025.111847_bib1","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/j.1471-4159.2004.02434.x","article-title":"Brain antioxidant systems in human methamphetamine users","volume":"89","author":"Mirecki","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbi.2025.111847_bib2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s12272-017-0897-y","article-title":"Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors","volume":"40","author":"Shin","year":"2017","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.cbi.2025.111847_bib3","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nm0696-699","article-title":"Striatal dopamine nerve terminal markers in human, chronic methamphetamine users","volume":"2","author":"Wilson","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib4","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1080\/10550490490459915","article-title":"Methamphetamine abstinence syndrome: preliminary findings","volume":"13","author":"Newton","year":"2004","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.cbi.2025.111847_bib5","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s00213-008-1408-0","article-title":"Prospective memory impairment in former users of methamphetamine","volume":"203","author":"Rendell","year":"2009","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.cbi.2025.111847_bib6","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1749-6632.1992.tb25965.x","article-title":"A lasting vulnerability to psychosis in patients with previous methamphetamine psychosis","volume":"654","author":"Sato","year":"1992","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cbi.2025.111847_bib7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s002130051058","article-title":"Increased sensitivity to stress and episode recurrence in spontaneous recurrence of methamphetamine psychosis","volume":"145","author":"Yui","year":"1999","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.cbi.2025.111847_bib8","doi-asserted-by":"crossref","first-page":"8417","DOI":"10.1523\/JNEUROSCI.18-20-08417.1998","article-title":"Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428","volume":"18","author":"McCann","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbi.2025.111847_bib9","doi-asserted-by":"crossref","first-page":"9414","DOI":"10.1523\/JNEUROSCI.21-23-09414.2001","article-title":"Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence","volume":"21","author":"Volkow","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbi.2025.111847_bib10","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1002\/mds.23263","article-title":"Incidence of Parkinson's disease among hospital patients with methamphetamine-use disorders","volume":"25","author":"Callaghan","year":"2010","journal-title":"Mov. Disord."},{"key":"10.1016\/j.cbi.2025.111847_bib11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.drugalcdep.2011.06.013","article-title":"Increased risk of Parkinson's disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs","volume":"120","author":"Callaghan","year":"2012","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cbi.2025.111847_bib12","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1007\/s12272-021-01341-7","article-title":"Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson's disease","volume":"44","author":"Shin","year":"2021","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.cbi.2025.111847_bib13","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0022-3565(25)10392-3","article-title":"Motor impairments after methamphetamine-induced neurotoxicity in the rat","volume":"263","author":"Walsh","year":"1992","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.cbi.2025.111847_bib14","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0006-8993(96)00968-7","article-title":"Neuroprotective effects of the dopamine D2\/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons","volume":"742","author":"Hall","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib15","first-page":"4136","article-title":"Protein kinase cdelta gene depletion protects against methamphetamine-induced impairments in recognition memory and ERK(1\/2) signaling via upregulation of glutathione Peroxidase-1 gene","volume":"55","author":"Tran","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cbi.2025.111847_bib16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.cnr.2006.09.006","article-title":"Neuroinflammation, oxidative stress and the pathogenesis of Parkinson's disease","volume":"6","author":"Mosley","year":"2006","journal-title":"Clin. Neurosci. Res."},{"key":"10.1016\/j.cbi.2025.111847_bib17","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.neuron.2016.03.038","article-title":"Understanding dopaminergic cell death pathways in parkinson disease","volume":"90","author":"Michel","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.cbi.2025.111847_bib18","first-page":"1817","article-title":"Damage to dopaminergic neurons by oxidative stress in parkinson's disease","volume":"41","author":"Guo","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib19","doi-asserted-by":"crossref","first-page":"9355","DOI":"10.1016\/S0021-9258(19)83523-8","article-title":"Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators)","volume":"254","author":"Demopoulos","year":"1979","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111847_bib20","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1046\/j.1365-2443.2000.00333.x","article-title":"Interaction between neurone and microglia mediated by platelet-activating factor","volume":"5","author":"Aihara","year":"2000","journal-title":"Genes Cells: Devot. Mol. Cell. Mech."},{"key":"10.1016\/j.cbi.2025.111847_bib21","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0929-7855(96)00541-X","article-title":"Platelet-activating factor in the modulation of excitatory amino acid neurotransmitter release and of gene expression","volume":"14","author":"Bazan","year":"1996","journal-title":"J. Lipid Mediat. Cell Signal"},{"key":"10.1016\/j.cbi.2025.111847_bib22","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0090-6980(02)00031-X","article-title":"Prostaglandins and other lipid mediators in Alzheimer's disease","volume":"68\u201369","author":"Bazan","year":"2002","journal-title":"Prostag. Other Lipid Mediat."},{"key":"10.1016\/j.cbi.2025.111847_bib23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2165\/00003495-199142010-00002","article-title":"Platelet activating factor (PAF). A review of its effects, antagonists and possible future clinical implications (part I)","volume":"42","author":"Koltai","year":"1991","journal-title":"Drugs"},{"key":"10.1016\/j.cbi.2025.111847_bib24","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12974-017-0866-x","article-title":"YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by \u03b2-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2","volume":"14","author":"Li","year":"2017","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.cbi.2025.111847_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24234414","article-title":"Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives","volume":"24","author":"Lordan","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.cbi.2025.111847_bib26","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.neuint.2013.05.010","article-title":"Platelet-activating factor receptor knockout mice are protected from MPTP-induced dopaminergic degeneration","volume":"63","author":"Kim","year":"2013","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib27","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1523\/JNEUROSCI.16-11-03590.1996","article-title":"Predominant expression of platelet-activating factor receptor in the rat brain microglia","volume":"16","author":"Mori","year":"1996","journal-title":"J. Neurosci.: Official J. Society for Neuroscience"},{"key":"10.1016\/j.cbi.2025.111847_bib28","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.1007\/s12035-016-0062-5","article-title":"Current understanding of platelet-activating factor signaling in central nervous system diseases","volume":"54","author":"Liu","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cbi.2025.111847_bib29","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.brainres.2007.01.094","article-title":"Platelet-activating factor antagonist (ABT-491) decreases neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury","volume":"1143","author":"Bozlu","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib30","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00001756-200201210-00009","article-title":"PAF antagonist treatment reduces pro-inflammatory cytokine mRNA after spinal cord injury","volume":"13","author":"Hostettler","year":"2002","journal-title":"Neuroreport"},{"key":"10.1016\/j.cbi.2025.111847_bib31","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/6947034","article-title":"A review on platelet activating factor inhibitors: could a new class of potent metal-based anti-inflammatory drugs induce anticancer properties?","volume":"2017","author":"Papakonstantinou","year":"2017","journal-title":"Bioinorgan. Chem. Appl."},{"key":"10.1016\/j.cbi.2025.111847_bib32","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.neuint.2019.01.014","article-title":"Significance of protein kinase C in the neuropsychotoxicity induced by methamphetamine-like psychostimulants","volume":"124","author":"Shin","year":"2019","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib33","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1196\/annals.1441.032","article-title":"Implication of activated astrocytes in the development of drug dependence: differences between methamphetamine and morphine","volume":"1141","author":"Narita","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cbi.2025.111847_bib34","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neuint.2011.03.022","article-title":"PKCdelta inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment","volume":"59","author":"Shin","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib35","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bbr.2012.04.001","article-title":"Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cdelta","volume":"232","author":"Shin","year":"2012","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib36","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1007\/s12035-013-8617-1","article-title":"Ginsenoside re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase Cdelta gene","volume":"49","author":"Shin","year":"2014","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cbi.2025.111847_bib37","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.freeradbiomed.2017.12.018","article-title":"PKCdelta-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity","volume":"115","author":"Dang","year":"2018","journal-title":"Free Radic. Biol. Med."},{"issue":"Pt 1","key":"10.1016\/j.cbi.2025.111847_bib38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1042\/bj2830159","article-title":"Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses","volume":"283","author":"Murphy","year":"1992","journal-title":"Biochem. J."},{"issue":"Pt 2","key":"10.1016\/j.cbi.2025.111847_bib39","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1042\/bj2900477","article-title":"Protein kinase C-mediated phospholipase A2 activation, platelet-activating factor generation and prostacyclin release in spontaneously beating rat cardiomyocytes","volume":"290","author":"Church","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.cbi.2025.111847_bib40","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1365-2885.2008.01020.x","article-title":"Regulation of platelet activating factor-induced equine platelet activation by intracellular kinases","volume":"32","author":"Brooks","year":"2009","journal-title":"J. Vet. Pharmacol. Therapeut."},{"key":"10.1016\/j.cbi.2025.111847_bib41","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neuro.2005.05.014","article-title":"Methamphetamine-induced striatal apoptosis in the mouse brain: comparison of a binge to an acute bolus drug administration","volume":"27","author":"Zhu","year":"2006","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.cbi.2025.111847_bib42","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.neuroscience.2006.02.055","article-title":"Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice","volume":"140","author":"Zhu","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbi.2025.111847_bib43","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/jpi.12195","article-title":"Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCdelta gene","volume":"58","author":"Nguyen","year":"2015","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.cbi.2025.111847_bib44","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF03033973","article-title":"Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review","volume":"8","author":"Cadet","year":"2005","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.cbi.2025.111847_bib45","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.neuint.2017.04.013","article-title":"The role of system Xc(-) in methamphetamine-induced dopaminergic neurotoxicity in mice","volume":"108","author":"Dang","year":"2017","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib46","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12974-016-0478-x","article-title":"Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK","volume":"13","author":"Dang","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.cbi.2025.111847_bib47","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.freeradbiomed.2017.03.033","article-title":"Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice","volume":"108","author":"Dang","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib48","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1471-4159.2009.06330.x","article-title":"The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice","volume":"111","author":"Zhu","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbi.2025.111847_bib49","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.neuroscience.2011.07.020","article-title":"A single high dose of methamphetamine induces apoptotic and necrotic striatal cell loss lasting up to 3 months in mice","volume":"193","author":"Tulloch","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbi.2025.111847_bib50","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s12640-020-00177-1","article-title":"Epigallocatechin gallate mitigates the methamphetamine-induced striatal dopamine terminal toxicity by preventing oxidative stress in the mouse brain","volume":"37","author":"Pan","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.cbi.2025.111847_bib51","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1084\/jem.187.11.1779","article-title":"Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor","volume":"187","author":"Ishii","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib52","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.neuint.2013.05.010","article-title":"Platelet-activating factor receptor knockout mice are protected from MPTP-induced dopaminergic degeneration","volume":"63","author":"Kim","year":"2013","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib53","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.brainresbull.2017.11.004","article-title":"Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-kappaB","volume":"137","author":"Tran","year":"2018","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.cbi.2025.111847_bib54","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/416865a","article-title":"Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta","volume":"416","author":"Miyamoto","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2025.111847_bib55","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neuint.2011.03.022","article-title":"PKC\u03b4 inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment","volume":"59","author":"Shin","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib56","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bbr.2012.04.001","article-title":"Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase C\u03b4","volume":"232","author":"Shin","year":"2012","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib57","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.neuroscience.2016.09.007","article-title":"Adenosine A1 receptor antagonist mitigates deleterious effects of sleep deprivation on adult neurogenesis and spatial reference memory in rats","volume":"337","author":"Chauhan","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbi.2025.111847_bib58","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ejphar.2017.02.046","article-title":"Ameliorative effects of sildenafil and\/or febuxostat on doxorubicin-induced nephrotoxicity in rats","volume":"805","author":"Khames","year":"2017","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.cbi.2025.111847_bib59","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.ibneur.2025.02.016","article-title":"Effects of intracerebroventricular administration of dimethyl sulfoxide on hippocampal electrophysiology in mice","volume":"18","author":"Spanoghe","year":"2025","journal-title":"IBRO Neurosci. Rep."},{"key":"10.1016\/j.cbi.2025.111847_bib60","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neuint.2018.12.017","article-title":"P53 knockout mice are protected from cocaine-induced kindling behaviors via inhibiting mitochondrial oxidative burdens, mitochondrial dysfunction, and proapoptotic changes","volume":"124","author":"Mai","year":"2019","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118494","article-title":"Enhanced neurogenesis is involved in neuroprotection provided by rottlerin against trimethyltin-induced delayed apoptotic neuronal damage","volume":"262","author":"Hwang","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.cbi.2025.111847_bib62","first-page":"1","article-title":"Far-infrared radiation-mediated GPx-1\/eNOS\/ERK signaling contributes to the protective potential against methamphetamine-caused impairments in recognition memory in mice","author":"Shin","year":"2025","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.cbi.2025.111847_bib63","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1006\/exnr.2002.7919","article-title":"Induction and activation of protein kinase C delta in hippocampus and cortex after kainic acid treatment","volume":"176","author":"Kaasinen","year":"2002","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cbi.2025.111847_bib64","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.nbd.2016.04.008","article-title":"Protein kinase C\u03b4 upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease","volume":"93","author":"Gordon","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.cbi.2025.111847_bib65","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neuint.2017.11.017","article-title":"Role of dopamine D1 receptor in 3-fluoromethamphetamine-induced neurotoxicity in mice","volume":"113","author":"Nguyen","year":"2018","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cbi.2025.111847_bib66","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1523\/JNEUROSCI.14-05-02924.1994","article-title":"Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes","volume":"14","author":"Volterra","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbi.2025.111847_bib67","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1074\/jbc.271.11.5976","article-title":"Peroxynitrite inhibits glutamate transporter subtypes","volume":"271","author":"Trotti","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111847_bib68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/jpet.104.070961","article-title":"Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation","volume":"311","author":"Thomas","year":"2004","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.cbi.2025.111847_bib69","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0169-328X(01)00184-X","article-title":"Methamphetamine causes widespread apoptosis in the mouse brain: evidence from using an improved TUNEL histochemical method","volume":"93","author":"Deng","year":"2001","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib70","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.neuroscience.2011.06.006","article-title":"Outbred ICR\/CD1 mice display more severe neuroinflammation mediated by microglial TLR4\/CD14 activation than inbred C57Bl\/6 mice","volume":"190","author":"Nikodemova","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbi.2025.111847_bib71","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.bbr.2017.04.001","article-title":"Manipulation of dopamine metabolism contributes to attenuating innate high locomotor activity in ICR mice","volume":"328","author":"Yamaguchi","year":"2017","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib72","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/S0891-5849(00)00221-5","article-title":"Protein kinase C signaling and oxidative stress","volume":"28","author":"Gopalakrishna","year":"2000","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib73","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nature09788","article-title":"Caspase signalling controls microglia activation and neurotoxicity","volume":"472","author":"Burguillos","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2025.111847_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2019.101695","article-title":"Platelets: the missing link between the blood and brain?","volume":"183","author":"Leiter","year":"2019","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.cbi.2025.111847_bib75","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1182\/blood-2013-12-544445","article-title":"Platelets induce apoptosis via membrane-bound FasL","volume":"126","author":"Schleicher","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2025.111847_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/jcm8020162","article-title":"Platelet depletion is effective in ameliorating anxiety-like behavior and reducing the pro-inflammatory environment in the hippocampus in murine experimental autoimmune encephalomyelitis","volume":"8","author":"Kocovski","year":"2019","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib77","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.expneurol.2015.03.018","article-title":"Lesion-induced accumulation of platelets promotes survival of adult neural stem\/progenitor cells","volume":"269","author":"Kazanis","year":"2015","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cbi.2025.111847_bib78","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0058979","article-title":"Platelets recognize brain-specific glycolipid structures, respond to neurovascular damage and promote neuroinflammation","volume":"8","author":"Sotnikov","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cbi.2025.111847_bib79","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.stemcr.2019.02.009","article-title":"Exercise-induced activated platelets increase adult hippocampal precursor proliferation and promote neuronal differentiation","volume":"12","author":"Leiter","year":"2019","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.cbi.2025.111847_bib80","doi-asserted-by":"crossref","first-page":"747","DOI":"10.3389\/fimmu.2020.00747","article-title":"Platelets in neurodegenerative conditions-friend or foe?","volume":"11","author":"Leiter","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cbi.2025.111847_bib81","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/rth2.12254","article-title":"Blood platelets: circulating mirrors of neurons?","volume":"3","author":"Canobbio","year":"2019","journal-title":"Res. Pract. Thromb. Haemost."},{"key":"10.1016\/j.cbi.2025.111847_bib82","doi-asserted-by":"crossref","first-page":"30024","DOI":"10.1074\/jbc.M604504200","article-title":"Essential role of protein kinase C delta in platelet signaling, alpha IIb beta 3 activation, and thromboxane A2 release","volume":"281","author":"Yacoub","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111847_bib83","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1074\/jbc.M306960200","article-title":"Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets","volume":"279","author":"Murugappan","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111847_bib84","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195379","article-title":"Role of protein kinase C-delta in regulating platelet activation and platelet-leukocyte interaction during sepsis","volume":"13","author":"Liverani","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.cbi.2025.111847_bib85","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1471-4159.2007.04740.x","article-title":"Platelet activating factor-induced neuronal apoptosis is initiated independently of its G-protein coupled PAF receptor and is inhibited by the benzoate orsellinic acid","volume":"103","author":"Ryan","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbi.2025.111847_bib86","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1046\/j.1365-2443.2000.00333.x","article-title":"Interaction between neurone and microglia mediated by platelet-activating factor","volume":"5","author":"Aihara","year":"2000","journal-title":"Genes Cells"},{"key":"10.1016\/j.cbi.2025.111847_bib87","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1046\/j.1471-4159.1995.64010121.x","article-title":"myc-immortalized microglial cells express a functional platelet-activating factor receptor","volume":"64","author":"Righi","year":"1995","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbi.2025.111847_bib88","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0165-6147(03)00176-7","article-title":"Novel anti-inflammatory therapy for Parkinson's disease","volume":"24","author":"Gao","year":"2003","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.cbi.2025.111847_bib89","first-page":"169","article-title":"Characterization of platelet-activating factor (PAF) receptor in the rat brain","volume":"6","author":"Bito","year":"1993","journal-title":"J. Lipid Mediat."},{"key":"10.1016\/j.cbi.2025.111847_bib90","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1523\/JNEUROSCI.16-11-03590.1996","article-title":"Predominant expression of platelet-activating factor receptor in the rat brain microglia","volume":"16","author":"Mori","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbi.2025.111847_bib91","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1742-2094-9-124","article-title":"Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice","volume":"9","author":"Wang","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.cbi.2025.111847_bib92","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.brainres.2005.05.049","article-title":"MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity","volume":"1050","author":"Thomas","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib93","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00005-012-0181-2","article-title":"The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain","volume":"60","author":"Varnum","year":"2012","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"key":"10.1016\/j.cbi.2025.111847_bib94","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/oxfordjournals.jbchem.a003145","article-title":"Platelet-activating factor acetylhydrolase (PAF-AH)","volume":"131","author":"Arai","year":"2002","journal-title":"J. Biochem."},{"key":"10.1016\/j.cbi.2025.111847_bib95","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/(SICI)1097-4547(19990715)57:2<176::AID-JNR3>3.0.CO;2-U","article-title":"Platelet-activating factor (PAF) acetylhydrolase activity, LIS1 expression, and seizures","volume":"57","author":"Shmueli","year":"1999","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.cbi.2025.111847_bib96","doi-asserted-by":"crossref","first-page":"23150","DOI":"10.1016\/S0021-9258(17)31632-0","article-title":"The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase","volume":"269","author":"Hattori","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2025.111847_bib97","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S1388-1981(00)00114-1","article-title":"Platelet-activating factor acetylhydrolases in health and disease","volume":"1488","author":"Tjoelker","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbi.2025.111847_bib98","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0006-8993(83)90602-9","article-title":"Alpha-methyltyrosine attenuates and reserpine increases methamphetamine-induced neuronal changes","volume":"270","author":"Wagner","year":"1983","journal-title":"Brain Res."},{"key":"10.1016\/j.cbi.2025.111847_bib99","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/0028-3908(83)90075-8","article-title":"Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine","volume":"22","author":"Ricaurte","year":"1983","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cbi.2025.111847_bib100","doi-asserted-by":"crossref","first-page":"54","DOI":"10.2174\/157015911795016930","article-title":"Role of sigma receptors in methamphetamine-induced neurotoxicity","volume":"9","author":"Kaushal","year":"2011","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.cbi.2025.111847_bib101","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1523\/JNEUROSCI.19-07-02424.1999","article-title":"Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice","volume":"19","author":"Fumagalli","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbi.2025.111847_bib102","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.bbrc.2018.06.084","article-title":"Scallop-derived plasmalogens attenuate the activation of PKC\u03b4 associated with the brain inflammation","volume":"503","author":"Sejimo","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cbi.2025.111847_bib103","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.freeradbiomed.2017.12.018","article-title":"PKC\u03b4-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity","volume":"115","author":"Dang","year":"2018","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.cbi.2025.111847_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.113627","article-title":"Ginsenoside Re mitigates memory impairments in aged GPx-1 KO mice by inhibiting the interplay between PAFR, NF\u03baB, and microgliosis in the hippocampus","volume":"173","author":"Shin","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.cbi.2025.111847_bib105","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1007\/s12035-013-8617-1","article-title":"Ginsenoside Re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase C\u03b4 gene","volume":"49","author":"Shin","year":"2014","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cbi.2025.111847_bib106","article-title":"Ginsenoside Re exerts neuroprotective in MPTP mice: potential links to gut microbiota and serum metabolism","volume":"282","author":"Li","year":"2025","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cbi.2025.111847_bib107","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.freeradbiomed.2022.07.003","article-title":"Ginsenoside Re attenuates memory impairments in aged Klotho deficient mice via interactive modulations of angiotensin II AT1 receptor, Nrf2 and GPx-1 gene","volume":"189","author":"Nguyen","year":"2022","journal-title":"Free Radic. Biol. Med."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725004776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725004776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:34:36Z","timestamp":1777379676000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279725004776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":107,"alternative-id":["S0009279725004776"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111847","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Critical interplay between PAF receptor and PKC\u03b4 is involved in dopaminergic insult evoked by methamphetamine in mice","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111847","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111847"}}