{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:08:14Z","timestamp":1789762094775,"version":"4.0.1"},"reference-count":98,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007335","name":"Ministry of Higher Education and Scientific Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007335","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010450","name":"Ministry of Higher Education and Scientific Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010450","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.cbi.2025.111891","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T07:15:39Z","timestamp":1766992539000},"page":"111891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Implications of early-life BPS-induced thyroid disruption on adult female reproductive disorders"],"prefix":"10.1016","volume":"425","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0309-2353","authenticated-orcid":false,"given":"Lina","family":"Chouchene","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariem Ben","family":"Rhouma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"Boughammoura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4025-8765","authenticated-orcid":false,"given":"Imed","family":"Messaoudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaouthar","family":"Kessabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2025.111891_bib1","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1093\/humupd\/dmac005","article-title":"Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine","volume":"28","author":"S\u00e1nchez-Garrido","year":"2022","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.cbi.2025.111891_bib2","article-title":"Gestational dibutyl phthalate exposure impairs primordial folliculogenesis in mice through autophagy activation and NOTCH2 signal interruption","author":"Zhang","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.944776","article-title":"Becoming female: ovarian differentiation from an evolutionary perspective","volume":"10","author":"Nicol","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1093\/biolre\/ioaa232","article-title":"Developmental programming of the female reproductive system-a review","volume":"104","author":"Yao","year":"2021","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib5","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/978-3-031-32554-0_2","article-title":"Role of hormones during gestation and early development: pathways involved in developmental programming","volume":"1428","author":"Abruzzese","year":"2023","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib6","doi-asserted-by":"crossref","first-page":"67925","DOI":"10.1007\/s11356-021-16489-4","article-title":"Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?","volume":"28","author":"Priya","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.cbi.2025.111891_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1162015","article-title":"Reproductive toxicity of combined effects of endocrine disruptors on human reproduction","volume":"11","author":"Dutta","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.reprotox.2025.108858","article-title":"Prenatal exposure to an environmentally relevant phthalate mixture alters oxidative stress, apoptosis, cell cycle regulators, and steroidogenic factors in the ovaries of F1 mice","volume":"132","author":"Fletcher","year":"2025","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1324993","article-title":"The adverse role of endocrine disrupting chemicals in the reproductive system","volume":"14","author":"Pan","year":"2024","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.cbi.2025.111891_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117385","article-title":"Endocrine disruptors: unravelling the link between chemical exposure and Women's reproductive health","volume":"241","author":"Hassan","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.cbi.2025.111891_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-81093-8","article-title":"Prenatal exposure to diethylstilbestrol has multigenerational effects on folliculogenesis","volume":"14","author":"Rogers","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2025.111891_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.125966","article-title":"Long-term and low-dose exposure to triclosan induces POI phenotype in female offspring mice","volume":"372","author":"Gan","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2025.111891_bib13","series-title":"1 in 6 People Globally Affected by Infertility","year":"2023"},{"key":"10.1016\/j.cbi.2025.111891_bib15","first-page":"249","article-title":"WHO fact sheet on infertility gives hope to millions of infertile couples worldwide","volume":"12","author":"Ombelet","year":"2020","journal-title":"Facts Views Vis Obgyn"},{"key":"10.1016\/j.cbi.2025.111891_bib18","doi-asserted-by":"crossref","first-page":"433","DOI":"10.17221\/81\/2015-CJAS","article-title":"Bisphenol S instead of bisphenol A: a story of reproductive disruption by regretable substitution-a review","volume":"61","author":"\u017dalmanov\u00e1","year":"2016","journal-title":"Czech J. Anim. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib19","first-page":"1321","article-title":"Bisphenols come in different flavors: is \u201cS\u201d Better Than \u201cA\u201d","volume":"157","author":"Ben-Jonathan","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbi.2025.111891_bib20","doi-asserted-by":"crossref","first-page":"6500","DOI":"10.3390\/ma16196500","article-title":"Bisphenols\u2014A threat to the natural environment","volume":"16","author":"Zaborowska","year":"2023","journal-title":"Materials"},{"key":"10.1016\/j.cbi.2025.111891_bib21","doi-asserted-by":"crossref","first-page":"6617","DOI":"10.1021\/acs.est.8b00776","article-title":"Thyroid disruption by bisphenol S analogues via thyroid hormone receptor \u03b2: in vitro, in vivo, and molecular dynamics simulation study","volume":"52","author":"Lu","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2025.111891_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2023.105697","article-title":"Bisphenol S and F affect cell cycle distribution and steroidogenic activity of human ovarian granulosa cells, but not primary granulosa tumour cells","volume":"93","author":"G\u0142\u00f3d","year":"2023","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.cbi.2025.111891_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e16848","article-title":"Different types of bisphenols alter ovarian steroidogenesis: special attention to BPA","volume":"9","author":"Shoorei","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.cbi.2025.111891_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114036","article-title":"The mixture effects of bisphenol derivatives on estrogen receptor and androgen receptor","volume":"260","author":"Park","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2025.111891_bib25","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/s42003-024-06449-2","article-title":"Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP\/PKA signaling pathway","volume":"7","author":"Zhang","year":"2024","journal-title":"Commun. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib26","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1007\/s00216-015-8469-9","article-title":"Determination of bisphenol A and related substitutes\/analogues in human breast milk using gas chromatography-tandem mass spectrometry","volume":"407","author":"Deceuninck","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.cbi.2025.111891_bib27","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.chemosphere.2017.12.118","article-title":"Comparative effects of bisphenol S and Bisphenol A on the development of female reproductive system in rats; a neonatal exposure study","volume":"197","author":"Ahsan","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2025.111891_bib28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/10408444.2019.1701986","article-title":"Substitution of bisphenol A: a review of the carcinogenicity, reproductive toxicity, and endocrine disruption potential of alternative substances","volume":"50","author":"den Braver-Sewradj","year":"2020","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib29","doi-asserted-by":"crossref","first-page":"905","DOI":"10.3390\/toxics11110905","article-title":"Association between urinary BPA substitutes and precocious puberty among girls: a single-exposure and mixed exposure approach from a Chinese case-control study","volume":"11","author":"Bigambo","year":"2023","journal-title":"Toxics"},{"key":"10.1016\/j.cbi.2025.111891_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.172379","article-title":"Reproductive and transgenerational toxicity of bisphenol S exposure in pregnant rats: insights into hormonal imbalance and steroid biosynthesis pathway disruption","volume":"927","author":"Zhao","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2025.111891_bib31","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/toxsci\/kfz124","article-title":"Prenatal exposure to bisphenol A, E, and S induces transgenerational effects on female reproductive functions in mice","volume":"170","author":"Shi","year":"2019","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib32","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/toxsci\/kfz014","article-title":"Prenatal exposure to bisphenol A analogues on female reproductive functions in mice","volume":"168","author":"Shi","year":"2019","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib33","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1210\/en.2015-1785","article-title":"Actions of bisphenol A and bisphenol S on the reproductive neuroendocrine system during early development in zebrafish","volume":"157","author":"Qiu","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbi.2025.111891_bib34","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12869","article-title":"BPS\u2010induced ovarian dysfunction: protective actions of melatonin via modulation of SIRT\u20101\/Nrf2\/NF\u0138B and IR\/PI3K\/pAkt\/GLUT\u20104 expressions in adult golden hamster","volume":"75","author":"Pal","year":"2023","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.cbi.2025.111891_bib35","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3390\/biomedicines7010005","article-title":"Hypothalamic-pituitary-ovarian axis disorders impacting female fertility","volume":"7","author":"Mikhael","year":"2019","journal-title":"Biomedicines"},{"key":"10.1016\/j.cbi.2025.111891_bib36","first-page":"516","article-title":"Bisphenol S (BPS) alters maternal behavior and brain in mice exposed during pregnancy\/lactation and their daughters","volume":"158","author":"Catanese","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbi.2025.111891_bib37","doi-asserted-by":"crossref","DOI":"10.1007\/s42000-025-00638-2","article-title":"The deleterious effect of bisphenol S on early embryo development of mice","author":"Mantzouki","year":"2025","journal-title":"Hormones (Basel)"},{"key":"10.1016\/j.cbi.2025.111891_bib38","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.scitotenv.2017.09.194","article-title":"Occurrence of bisphenol S in the environment and implications for human exposure: a short review","volume":"615","author":"Wu","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2025.111891_bib39","doi-asserted-by":"crossref","first-page":"52596","DOI":"10.1007\/s11356-024-34666-z","article-title":"Effect of thyroid disruption on ovarian development following maternal exposure to bisphenol S","volume":"31","author":"Chouchene","year":"2024","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.cbi.2025.111891_bib40","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12940-015-0051-6","article-title":"Endocrine disruptors alter social behaviors and indirectly influence social hierarchies via changes in body weight","volume":"14","author":"Kim","year":"2015","journal-title":"Environ. Health"},{"key":"10.1016\/j.cbi.2025.111891_bib41","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.reprotox.2018.03.003","article-title":"Low dose bisphenol S or ethinyl estradiol exposures during the perinatal period alter female mouse mammary gland development","volume":"78","author":"Kolla","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib42","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1096\/fj.201601166RR","article-title":"Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration","volume":"31","author":"Ma","year":"2017","journal-title":"FASEB J."},{"key":"10.1016\/j.cbi.2025.111891_bib43","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.neuroscience.2010.03.039","article-title":"Regulation of early spontaneous network activity and GABAergic neurons development by thyroid hormone","volume":"168","author":"Westerholz","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbi.2025.111891_bib44","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1590\/S1519-69842002000400008","article-title":"Determination of the estrous cycle phases of rats: some helpful considerations","volume":"62","author":"Marcondes","year":"2002","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib45","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/jrf.0.0170555","article-title":"Proposal for a classification of oocytes and follicles in the mouse ovary","volume":"17","author":"Pedersen","year":"1968","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.cbi.2025.111891_bib46","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.cbi.2025.111891_bib47","series-title":"Handbook Methods for Oxygen Radical Research","article-title":"Catalase activity","author":"Claiborne","year":"1985"},{"key":"10.1016\/j.cbi.2025.111891_bib48","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"[30] microsomal lipid peroxidation","author":"Buege","year":"1978"},{"key":"10.1016\/j.cbi.2025.111891_bib49","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbi.2025.111891_bib50","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbi.2025.111891_bib51","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.cbi.2025.111891_bib52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.neuro.2025.04.007","article-title":"The effects of oral gestational particulate matter 10 exposure: insights into neurodevelopmental milestones, inhibitory control, adult sociability, and object recognition","volume":"108","author":"Ruiz-Sobremazas","year":"2025","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.cbi.2025.111891_bib53","doi-asserted-by":"crossref","DOI":"10.3389\/ftox.2023.1264238","article-title":"Prenatal exposure to bisphenol A and\/or diethylhexyl phthalate alters stress responses in rat offspring in a sex- and dose-dependent manner","volume":"5","author":"Kaimal","year":"2023","journal-title":"Front. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib54","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1017\/S2040174418000764","article-title":"Transgenerational effects of maternal bisphenol: a exposure on offspring metabolic health","volume":"10","author":"Bansal","year":"2019","journal-title":"J. Dev. Orig. Health Dis."},{"key":"10.1016\/j.cbi.2025.111891_bib55","first-page":"273","article-title":"Thyroid disease in pregnancy","volume":"89","author":"Carney","year":"2014","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.cbi.2025.111891_bib56","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.reprotox.2021.11.004","article-title":"Could maternal thyroid function during pregnancy affect daughters' age at menarche through child growth? A mediation analysis","volume":"107","author":"Siegel","year":"2022","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib57","first-page":"907","article-title":"Thyroid hormones and female reproduction","volume":"99","author":"Silva","year":"2018","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib58","series-title":"Thyroid Disease as a Teratogen","author":"Devabhaktuni","year":"2025"},{"key":"10.1016\/j.cbi.2025.111891_bib59","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232315113","article-title":"Thyroid hormone transporters in pregnancy and fetal development","volume":"23","author":"Chen","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib60","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/mrd.23647","article-title":"Thyroid hormones: metabolism and transportation in the fetoplacental unit","volume":"89","author":"Zu\u00f1iga","year":"2022","journal-title":"Mol. Reprod. Dev."},{"issue":"Suppl 2","key":"10.1016\/j.cbi.2025.111891_bib61","first-page":"253","article-title":"Thyroid function and puberty","volume":"16","author":"Weber","year":"2003","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.cbi.2025.111891_bib62","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1749-6632.2000.tb06217.x","article-title":"The hypothalamic-pituitary-thyroid axis and the female reproductive system","volume":"900","author":"Doufas","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib63","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.fertnstert.2022.03.018","article-title":"Maternal thyroid disease in pregnancy and timing of pubertal development in sons and daughters","volume":"118","author":"Lunddorf","year":"2022","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.cbi.2025.111891_bib64","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1210\/er.2009-0041","article-title":"Thyroid function and human reproductive health","volume":"31","author":"Krassas","year":"2010","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.cbi.2025.111891_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128445","article-title":"Detrimental effect of Bisphenol S in mouse germ cell cyst breakdown and primordial follicle assembly","volume":"264","author":"Liu","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2025.111891_bib66","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1530\/REP-18-0092","article-title":"Long-term exposure to very low doses of bisphenol S affects female reproduction","volume":"156","author":"Nevoral","year":"2018","journal-title":"Reproduction"},{"key":"10.1016\/j.cbi.2025.111891_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.161660","article-title":"Exploration of the damage and mechanisms of BPS exposure on the uterus and ovary of adult female mice","volume":"868","author":"Yue","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2025.111891_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115382","article-title":"Maternal Bisphenol S exposure affects the reproductive capacity of F1 and F2 offspring in mice","volume":"267","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2025.111891_bib69","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1093\/humupd\/dmae025","article-title":"Impact of Bisphenol A and its alternatives on oocyte health: a scoping review","volume":"30","author":"Peters","year":"2024","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.cbi.2025.111891_bib70","doi-asserted-by":"crossref","first-page":"R103","DOI":"10.1530\/JME-14-0220","article-title":"PI3K\/PTEN\/Akt and TSC\/mTOR signaling pathways, ovarian dysfunction, and infertility: an update","volume":"53","author":"Makker","year":"2014","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.cbi.2025.111891_bib71","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.reprotox.2012.02.005","article-title":"Effects of estrogenic compounds on neonatal oocyte development","volume":"34","author":"Karavan","year":"2012","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2023.111892","article-title":"Impairment of steroidogenesis and follicle development after bisphenol A exposure during pregnancy and lactation in the ovaries of Mongolian gerbils aged females","author":"Ruiz","year":"2023","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.cbi.2025.111891_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.130118","article-title":"Prenatal exposure to bisphenols affects pregnancy outcomes and offspring development in rats","volume":"276","author":"Kaimal","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2025.111891_bib74","first-page":"403","article-title":"Stereological study on the effect of vitamin C in preventing the adverse effects of bisphenol A on rat ovary","volume":"14","author":"Soleimani Mehranjani","year":"2016","journal-title":"Int. J. Reprod. Biomed."},{"key":"10.1016\/j.cbi.2025.111891_bib75","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1093\/toxsci\/kfi202","article-title":"Effects of two fungicides with multiple modes of action on reproductive endocrine function in the fathead minnow (Pimephales promelas)","volume":"86","author":"Ankley","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib76","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.cbi.2011.06.010","article-title":"Cadmium-induced ovarian pathophysiology is mediated by change in gene expression pattern of zinc transporters in zebrafish (Danio rerio)","volume":"193","author":"Chouchene","year":"2011","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2025.111891_bib77","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.cca.2004.09.004","article-title":"Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure","volume":"139","author":"Maack","year":"2004","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.cbi.2025.111891_bib78","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1095\/biolreprod.108.071217","article-title":"Germ cell-specific transcriptional regulator sohlh2 is essential for early mouse folliculogenesis and oocyte-specific gene expression","volume":"79","author":"Choi","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib79","doi-asserted-by":"crossref","first-page":"3525","DOI":"10.1093\/nar\/gkaa101","article-title":"FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation","volume":"48","author":"Wang","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cbi.2025.111891_bib80","doi-asserted-by":"crossref","DOI":"10.1126\/science.1260419","article-title":"Proteomics. Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.cbi.2025.111891_bib81","unstructured":"FIGLA protein expression summary - the human protein atlas, (n.d.). https:\/\/www.proteinatlas.org\/ENSG00000183733-FIGLA?utm_source=chatgpt.com (accessed December 14, 2025)."},{"key":"10.1016\/j.cbi.2025.111891_bib82","doi-asserted-by":"crossref","first-page":"9842","DOI":"10.1038\/s41598-021-89052-3","article-title":"Figla promotes secondary follicle growth in mature mice","volume":"11","author":"Okunomiya","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2025.111891_bib83","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1095\/biolreprod.104.032474","article-title":"H1FOO is coupled to the initiation of oocytic growth","volume":"72","author":"Tanaka","year":"2005","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib84","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1530\/REP-21-0233","article-title":"Involvement of the linker histone H1Foo in the regulation of oogenesis","volume":"164","author":"Funaya","year":"2022","journal-title":"Reproduction"},{"key":"10.1016\/j.cbi.2025.111891_bib85","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s40104-024-01107-3","article-title":"The assembly and activation of the PANoptosome promote porcine granulosa cell programmed cell death during follicular atresia","volume":"15","author":"Wu","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.cbi.2025.111891_bib86","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.reprotox.2013.09.002","article-title":"Prepubertal bisphenol A exposure interferes with ovarian follicle development and its relevant gene expression","volume":"44","author":"Li","year":"2014","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.cbi.2025.111891_bib87","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1210\/er.2008-0048","article-title":"Molecular mechanisms underlying the activation of mammalian primordial follicles","volume":"30","author":"Adhikari","year":"2009","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.cbi.2025.111891_bib88","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ydbio.2008.06.017","article-title":"Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth","volume":"321","author":"John","year":"2008","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cbi.2025.111891_bib89","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.tem.2009.10.001","article-title":"Mechanisms maintaining the dormancy and survival of mammalian primordial follicles","volume":"21","author":"Reddy","year":"2010","journal-title":"Trends Endocrinol. Metabol."},{"key":"10.1016\/j.cbi.2025.111891_bib90","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232214379","article-title":"DNA damage stress response and follicle activation: signaling routes of Mammalian ovarian reserve","volume":"23","author":"Gonfloni","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib91","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1095\/biolreprod.115.136515","article-title":"Dietary-Induced chronic hypothyroidism negatively affects rat follicular development and ovulation rate and is associated with oxidative stress","volume":"94","author":"Meng","year":"2016","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib92","doi-asserted-by":"crossref","first-page":"9815","DOI":"10.3390\/ijms24129815","article-title":"The thyroid hormone axis and female reproduction","volume":"24","author":"Brown","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib93","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2024.1466967","article-title":"Endocrine disruptor chemicals exposure and female fertility declining: from pathophysiology to epigenetic risks","volume":"12","author":"Tricotteaux-Zarqaoui","year":"2024","journal-title":"Front. Public Health"},{"key":"10.1016\/j.cbi.2025.111891_bib94","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/bs.apha.2021.03.008","article-title":"Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models","volume":"92","author":"Laws","year":"2021","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.cbi.2025.111891_bib95","series-title":"Encyclopedia of Dairy Sciences","first-page":"948","article-title":"Reproduction, events and management: estrous cycles: characteristics","author":"Crowe","year":"2022"},{"key":"10.1016\/j.cbi.2025.111891_bib96","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3390\/ijms23010512","article-title":"Estradiol signaling at the heart of folliculogenesis: its potential deregulation in human ovarian pathologies","volume":"23","author":"Chauvin","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbi.2025.111891_bib97","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1210\/jc.2018-00769","article-title":"Early-onset complete ovarian failure and lack of puberty in a woman with mutated estrogen receptor \u03b2 (ESR2)","volume":"103","author":"Lang-Muritano","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cbi.2025.111891_bib98","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.yfrne.2012.08.004","article-title":"Estradiol signaling in the regulation of reproduction and energy balance","volume":"33","author":"Sinchak","year":"2012","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.cbi.2025.111891_bib99","doi-asserted-by":"crossref","first-page":"R109","DOI":"10.1530\/JOE-17-0023","article-title":"Exposure to endocrine disruptors during adulthood: consequences for female fertility","volume":"233","author":"Rattan","year":"2017","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cbi.2025.111891_bib100","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1095\/biolreprod.104.028175","article-title":"Estrogen actions on follicle formation and early follicle development","volume":"71","author":"Britt","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbi.2025.111891_bib101","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1146\/annurev-animal-031412-103647","article-title":"In vivo and in vitro environmental effects on Mammalian oocyte quality","volume":"1","author":"Krisher","year":"2013","journal-title":"Annu. Rev. Anim. Biosci."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725005216?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279725005216?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:56:18Z","timestamp":1773928578000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279725005216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":98,"alternative-id":["S0009279725005216"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111891","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Implications of early-life BPS-induced thyroid disruption on adult female reproductive disorders","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2025.111891","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111891"}}