{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:16:46Z","timestamp":1783113406183,"version":"3.54.6"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32472336"],"award-info":[{"award-number":["32472336"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.cbi.2026.112175","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T07:29:28Z","timestamp":1779780568000},"page":"112175","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Elaidic acid induces hepatic lipid accumulation by inhibiting chaperone-mediated autophagy via the GAS5\/miR-27b-3p\/SNX10 axis"],"prefix":"10.1016","volume":"435","author":[{"given":"Yuelin","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzhu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingxi","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhuan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2026.112175_bib1","doi-asserted-by":"crossref","DOI":"10.3402\/fnr.v52i0.1651","article-title":"Ruminant and industrially produced trans fatty acids: health aspects","volume":"52","author":"Stender","year":"2008","journal-title":"Food Nutr. Res."},{"key":"10.1016\/j.cbi.2026.112175_bib2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nrendo.2009.79","article-title":"Trans fatty acids: effects on metabolic syndrome, heart disease and diabetes","volume":"5","author":"Micha","year":"2009","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.cbi.2026.112175_bib3","article-title":"Presence of trans-Fatty acids containing ingredients in pre-packaged foods and the availability of reported trans-Fat levels in Kenya and Nigeria","volume":"15","author":"Huang","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.cbi.2026.112175_bib4","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.ajcnut.2023.08.014","article-title":"Changes of trans and saturated fatty acid content in savory baked goods from 2015 to 2021 and their effect on consumers' intake using substitution models: a study conducted in Greece","volume":"118","author":"Marakis","year":"2023","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.cbi.2026.112175_bib5","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ijcard.2018.07.136","article-title":"Plasma trans-fatty acid and risk of nonalcoholic fatty liver disease: new data from national health and nutrition examination survey (NHANES)","volume":"272","author":"Mantovani","year":"2018","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.cbi.2026.112175_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2022.101199","article-title":"New research development on trans fatty acids in food: biological effects, analytical methods, formation mechanism, and mitigating measures","volume":"89","author":"Guo","year":"2023","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112175_bib7","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1002\/ejlt.201100037","article-title":"Trans fatty acid isomers and the trans-9\/trans-11 index in fat containing foods","volume":"113","author":"Kuhnt","year":"2011","journal-title":"Eur. J. Lipid Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112175_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mnfr.201900385","article-title":"Industrial trans fatty acids stimulate SREBP2-Mediated cholesterogenesis and promote non-alcoholic fatty liver disease","volume":"63","author":"Oteng","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.cbi.2026.112175_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/molecules21060705","article-title":"Trans-fatty acids aggravate obesity, insulin resistance and hepatic steatosis in C57BL\/6 mice, possibly by suppressing the IRS1 dependent pathway","volume":"21","author":"Zhao","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.cbi.2026.112175_bib10","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1080\/15548627.2021.1895658","article-title":"The m\u00e9nage \u00e0 trois of autophagy, lipid droplets and liver disease","volume":"18","author":"Filali-Mouncef","year":"2022","journal-title":"Autophagy"},{"key":"10.1016\/j.cbi.2026.112175_bib11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.cmet.2014.06.009","article-title":"Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation","volume":"20","author":"Schneider","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.cbi.2026.112175_bib12","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1080\/15548627.2015.1124226","article-title":"AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA","volume":"12","author":"Kaushik","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.cbi.2026.112175_bib13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.yexcr.2015.10.021","article-title":"Pathophysiology of lipid droplet proteins in liver diseases","volume":"340","author":"Carr","year":"2016","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.cbi.2026.112175_bib14","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/ncb3166","article-title":"Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis","volume":"17","author":"Kaushik","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cbi.2026.112175_bib15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.4161\/auto.4144","article-title":"Chaperone-mediated autophagy","volume":"3","author":"Dice","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.cbi.2026.112175_bib16","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1111\/liv.14492","article-title":"Disruption of Plin5 degradation by CMA causes lipid homeostasis imbalance in NAFLD","volume":"40","author":"Ma","year":"2020","journal-title":"Liver Int."},{"key":"10.1016\/j.cbi.2026.112175_bib17","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/emboj\/cdg002","article-title":"Cathepsin a regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor","volume":"22","author":"Cuervo","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.cbi.2026.112175_bib18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jhep.2018.01.038","article-title":"SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy","volume":"69","author":"You","year":"2018","journal-title":"J. Hepatol."},{"key":"10.1016\/j.cbi.2026.112175_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41576-023-00662-1","article-title":"Non-coding RNAs in disease: from mechanisms to therapeutics","volume":"25","author":"Nemeth","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.cbi.2026.112175_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12931-024-02895-y","article-title":"LncRNAH19 acts as a ceRNA of let-7 g to facilitate endothelial-to-mesenchymal transition in hypoxic pulmonary hypertension via regulating TGF-\u03b2 signalling pathway","volume":"25","author":"Yu","year":"2024","journal-title":"Respir. Res."},{"key":"10.1016\/j.cbi.2026.112175_bib21","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/s12276-025-01420-5","article-title":"LncRNA Gm35585 transcriptionally activates the peroxidase EHHADH against diet-induced fatty liver","volume":"57","author":"Jin","year":"2025","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.cbi.2026.112175_bib22","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/s41576-023-00611-y","article-title":"microRNAs in action: biogenesis, function and regulation","volume":"24","author":"Shang","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.cbi.2026.112175_bib23","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nature12986","article-title":"The multilayered complexity of ceRNA crosstalk and competition","volume":"505","author":"Tay","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2026.112175_bib24","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.clnu.2023.11.004","article-title":"LncRNA MIR22HG\/microRNA-9-3p\/IGF1 in nonalcoholic steatohepatitis, the ceRNA network increases fibrosis by inhibiting autophagy and promoting pyroptosis","volume":"43","author":"Chen","year":"2024","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.cbi.2026.112175_bib25","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1080\/15384101.2021.1875665","article-title":"LncRNA Neat1 expedites the progression of liver fibrosis in mice through targeting miR-148a-3p and miR-22-3p to upregulate Cyth3","volume":"20","author":"Huang","year":"2021","journal-title":"Cell Cycle"},{"key":"10.1016\/j.cbi.2026.112175_bib26","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1093\/nar\/gkad828","article-title":"LncRNADisease v3 . 0 : an updated database of long non-coding RNA-associated diseases","volume":"52","author":"Lin","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cbi.2026.112175_bib27","doi-asserted-by":"crossref","DOI":"10.1186\/s12944-024-02226-6","article-title":"Association between plasma trans fatty acids and serum \u03b1-klotho levels in adults in the United States of America: an analysis of the NHANES 2009\u20132010 datasets","volume":"23","author":"Liang","year":"2024","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.cbi.2026.112175_bib28","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","article-title":"Dose translation from animal to human studies revisited","volume":"22","author":"Reagan-shaw","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.cbi.2026.112175_bib29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3390\/nu15020381","article-title":"Ultra-processed food consumption is related to higher trans fatty acids, sugar intake, and micronutrient-impaired status in schoolchildren of Bahia, Brazil","volume":"15","author":"Acids","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.cbi.2026.112175_bib30","doi-asserted-by":"crossref","DOI":"10.26633\/RPSP.2023.45","article-title":"Industrially produced trans fat and saturated fat content of food products in Jamaica","volume":"47","author":"Perry","year":"2023","journal-title":"Rev. Panam. Salud P\u00fablic"},{"key":"10.1016\/j.cbi.2026.112175_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.114060","article-title":"Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway","volume":"181","author":"Lu","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.cbi.2026.112175_bib32","doi-asserted-by":"crossref","first-page":"16449","DOI":"10.1021\/acs.jafc.4c02508","article-title":"Bta-miR-200a regulates milk fat biosynthesis by targeting IRS2 to inhibit the PI3K\/Akt signal pathway in bovine mammary epithelial cells","volume":"72","author":"Tan","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbi.2026.112175_bib33","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.jhep.2023.08.023","article-title":"Hepatic steatosis aggravates atherosclerosis via small extracellular vesicle-mediated inhibition of cellular cholesterol efflux","volume":"79","author":"Chen","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.cbi.2026.112175_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.26633\/RPSP.2025.72","article-title":"\u00c1cidos grasos trans en el etiquetado nutricional y en la lista de ingredientes de productos preenvasados en Costa Rica, 2022","volume":"49","author":"N\u00fa\u00f1ez-Rivas","year":"2025","journal-title":"Rev. Panam. Salud P\u00fablic"},{"key":"10.1016\/j.cbi.2026.112175_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/nu13093087","article-title":"Analysis of fat content with special emphasis on trans isomers in frequently consumed food products in Egypt: the first steps in the trans fatty acid elimination roadmap","volume":"13","author":"Ismail","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.cbi.2026.112175_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jcb.30579","article-title":"Perilipins: a family of five fat-droplet storing proteins that play a significant role in fat homeostasis","volume":"125","author":"Chandrasekaran","year":"2024","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.cbi.2026.112175_bib37","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1002\/hep.22268","article-title":"Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis","volume":"47","author":"Straub","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.cbi.2026.112175_bib38","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1194\/jlr.M035063","article-title":"Perilipin-2-null mice are protected against diet-induced obesity, adipose infl ammation, and fatty liver disease","volume":"54","author":"McManaman","year":"2013","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112175_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcell.2021.826248","article-title":"Biogenesis and breakdown of lipid droplets in pathological conditions","volume":"9","author":"Fader Kaiser","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cbi.2026.112175_bib40","first-page":"1","article-title":"Chaperone mediated autophagy in the crosstalk of neurodegenerative diseases and metabolic disorders","volume":"10","author":"Alfaro","year":"2019","journal-title":"Front. Endocrinol. (Lausanne)."},{"key":"10.1016\/j.cbi.2026.112175_bib41","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-019-14164-4","article-title":"Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo","volume":"11","author":"Dong","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cbi.2026.112175_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2023.101784","article-title":"Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1","volume":"76","author":"Choi","year":"2023","journal-title":"Mol. Metabol."},{"key":"10.1016\/j.cbi.2026.112175_bib43","doi-asserted-by":"crossref","first-page":"27965","DOI":"10.1021\/acs.jafc.4c08430","article-title":"Apigenin reduces lipid droplet accumulation in hepatocytes by enhancing chaperone-mediated autophagy via AMPK","volume":"72","author":"Lu","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbi.2026.112175_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2021.707259","article-title":"Milk fat Globule-EGF factor 8 alleviates pancreatic fibrosis by inhibiting ER stress-induced chaperone-mediated autophagy in mice","volume":"12","author":"Ren","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.cbi.2026.112175_bib45","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1080\/15548627.2018.1474992","article-title":"Transcription factor NFE2L2\/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A","volume":"14","author":"Pajares","year":"2018","journal-title":"Autophagy"},{"key":"10.1016\/j.cbi.2026.112175_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/acel.13616","article-title":"Chaperone-mediated autophagy degrades Keap1 and promotes Nrf2-mediated antioxidative response","volume":"21","author":"Zhu","year":"2022","journal-title":"Aging Cell"},{"key":"10.1016\/j.cbi.2026.112175_bib47","first-page":"1","article-title":"Sorting nexins in protein homeostasis","volume":"10","author":"Hanley","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.cbi.2026.112175_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043056","article-title":"Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis","volume":"7","author":"Kita","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cbi.2026.112175_bib49","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.cmet.2013.07.004","article-title":"DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery","volume":"18","author":"Ahrens","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.cbi.2026.112175_bib50","doi-asserted-by":"crossref","first-page":"6451","DOI":"10.1016\/j.cell.2024.10.024","article-title":"Small and long non-coding RNAs: past, present, and future","volume":"187","author":"Chen","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.cbi.2026.112175_bib51","first-page":"1","article-title":"Research progress of long non-coding RNA GAS5 in malignant tumors","volume":"12","author":"Lin","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.cbi.2026.112175_bib52","doi-asserted-by":"crossref","first-page":"8370","DOI":"10.1080\/21655979.2022.2026858","article-title":"Long non-coding RNA GAS5 contributes to the progression of nonalcoholic fatty liver disease by targeting the microRNA-29a-3p\/NOTCH2 axis","volume":"13","author":"Cui","year":"2022","journal-title":"Bioengineered"},{"key":"10.1016\/j.cbi.2026.112175_bib53","first-page":"1","article-title":"LncRNA GAS5 knockdown mitigates hepatic lipid accumulation via regulating MiR-26a-5p\/PDE4B to activate cAMP\/CREB pathway","volume":"13","author":"Xu","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)."},{"key":"10.1016\/j.cbi.2026.112175_bib54","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1038\/s41418-023-01183-4","article-title":"GAS5 protects against nonalcoholic fatty liver disease via miR-28a-5p\/MARCH7\/NLRP3 axis-mediated pyroptosis","volume":"30","author":"Chen","year":"2023","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.cbi.2026.112175_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2023.155657","article-title":"SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis","volume":"146","author":"Shen","year":"2023","journal-title":"Metabolism"},{"key":"10.1016\/j.cbi.2026.112175_bib56","doi-asserted-by":"crossref","first-page":"3949","DOI":"10.1016\/j.apsb.2024.05.014","article-title":"Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism","volume":"14","author":"Li","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.cbi.2026.112175_bib57","doi-asserted-by":"crossref","first-page":"5805","DOI":"10.1073\/pnas.0507436103","article-title":"Consequences of the selective blockage of chaperone-mediated autophagy","volume":"103","author":"Massey","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cbi.2026.112175_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnut.2024.1511682","article-title":"Sesamin alleviates lipid accumulation induced by elaidic acid in L02 cells through TFEB regulated autophagy","volume":"11","author":"Liang","year":"2024","journal-title":"Front. Nutr."},{"key":"10.1016\/j.cbi.2026.112175_bib59","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.abb.2014.01.025","article-title":"Protein mediated fatty acid uptake: synergy between CD36\/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism","volume":"546","author":"Schneider","year":"2014","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cbi.2026.112175_bib60","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.bbalip.2017.11.006","article-title":"Cell culture models of fatty acid overload: problems and solutions","volume":"1863","author":"Alsabeeh","year":"2018","journal-title":"Biochim. Biophys. Acta, Mol. Cell Biol. Lipids"}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726002838?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726002838?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:23:19Z","timestamp":1783110199000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279726002838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":60,"alternative-id":["S0009279726002838"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112175","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elaidic acid induces hepatic lipid accumulation by inhibiting chaperone-mediated autophagy via the GAS5\/miR-27b-3p\/SNX10 axis","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112175","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112175"}}