{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T05:16:23Z","timestamp":1788498983189,"version":"build-2803163510"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012154","name":"Graduate Research and Innovation Projects of Jiangsu Province","doi-asserted-by":"publisher","award":["KYCX25 _3837"],"award-info":[{"award-number":["KYCX25 _3837"]}],"id":[{"id":"10.13039\/501100012154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574142"],"award-info":[{"award-number":["82574142"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.cbi.2026.112275","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T13:00:41Z","timestamp":1786021241000},"page":"112275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Gestational exposure to short-chain chlorinated paraffins induces sex-specific hepatic steatosis in adult mouse offspring"],"prefix":"10.1016","volume":"438","author":[{"given":"Xiaoke","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangsicheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoping","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilu","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufei","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7317-8016","authenticated-orcid":false,"given":"Xinyuan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2026.112275_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131878","article-title":"Determination of chlorinated paraffins (CPs): analytical conundrums and the pressing need for reliable and relevant standards","volume":"286","author":"Fernandes","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2026.112275_bib2","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1021\/acs.est.7b04761","article-title":"Screening of chlorinated paraffins and unsaturated analogues in commercial mixtures: confirmation of their occurrences in the atmosphere","volume":"52","author":"Li","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112275_bib3","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.envpol.2017.02.015","article-title":"Spatial and temporal trends of short- and medium-chain chlorinated paraffins in sediments off the urbanized coastal zones in China and Japan: a comparison study","volume":"224","author":"Zeng","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122379","article-title":"Freshwater environment risk assessment and derivation of human health ambient water quality criteria for SCCPs in China","volume":"336","author":"Liu","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib5","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.scitotenv.2017.10.026","article-title":"Short-chain chlorinated paraffins (SCCPs) in a freshwater food web from Dianshan Lake: occurrence level, congener pattern and trophic transfer","volume":"615","author":"Zhou","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112275_bib6","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s10653-026-03061-7","article-title":"Biota occurrence, accumulation, disposition and toxic effect of chlorinated paraffins","volume":"48","author":"Zhang","year":"2026","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.cbi.2026.112275_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108020","article-title":"Toxic effects and toxicological mechanisms of chlorinated paraffins: a review for insight into species sensitivity and toxicity difference","volume":"178","author":"Chen","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108527","article-title":"Exploring long-term global environmental impacts of chlorinated paraffins (CPs) in waste: implications for the Stockholm and Basel Conventions and the global plastic treaty","volume":"185","author":"Chen","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib9","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1039\/D3EM00235G","article-title":"Biomonitoring, exposure routes and risk assessment of chlorinated paraffins in humans: a mini-review","volume":"25","author":"Liao","year":"2023","journal-title":"Environ. Sci. Process. Impacts"},{"key":"10.1016\/j.cbi.2026.112275_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114520","article-title":"Short-chain chlorinated paraffins in various foods from Republic of Korea: levels, congener patterns, and human dietary exposure","volume":"263","author":"Lee","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2021.113049","article-title":"Bioaccumulation and trophic magnification of short chain chlorinated paraffins in marine organisms from East China Sea","volume":"173","author":"Hu","year":"2021","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.cbi.2026.112275_bib12","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.envpol.2017.10.022","article-title":"Dietary exposure to short- and medium-chain chlorinated paraffins in meat and meat products from 20 provinces of China","volume":"233","author":"Huang","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib13","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1021\/acs.est.6b05149","article-title":"High-throughput determination and characterization of Short-, Medium-, and long-chain chlorinated paraffins in human blood","volume":"51","author":"Li","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112275_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123690","article-title":"Short- and medium-chain chlorinated paraffins in breast milk in Shanghai, China: occurrence, characteristics, and risk assessment","volume":"347","author":"Wang","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envint.2017.03.013","article-title":"Health risks posed to infants in rural China by exposure to short- and medium-chain chlorinated paraffins in breast milk","volume":"103","author":"Xia","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105871","article-title":"Blood partitioning and whole-blood-based maternal transfer assessment of chlorinated paraffins in mother-infant pairs from South China","volume":"142","author":"Chen","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib17","doi-asserted-by":"crossref","first-page":"588S","DOI":"10.1080\/07315724.2004.10719428","article-title":"The developmental origins of adult disease","volume":"23","author":"Barker","year":"2004","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.cbi.2026.112275_bib18","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1203\/01.PDR.0000135998.08025.FB","article-title":"Developmental origins of disease paradigm: a mechanistic and evolutionary perspective","volume":"56","author":"Gluckman","year":"2004","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.cbi.2026.112275_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.138531","article-title":"Exposure to short-chain chlorinated paraffins induces mortality in marine medaka larvae through neurotoxicity and oxidative stress","volume":"494","author":"Do","year":"2025","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.cbi.2026.112275_bib20","doi-asserted-by":"crossref","first-page":"8149","DOI":"10.1021\/acs.est.1c00975","article-title":"Cross-Model comparison of transcriptomic dose-response of short-chain chlorinated paraffins","volume":"55","author":"Xia","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112275_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116304","article-title":"Developmental toxicity of short-chain chlorinated paraffins on early-stage chicken embryos in a shell-less (ex-ovo) incubation system","volume":"276","author":"Chen","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2026.112275_bib22","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/s41575-023-00775-2","article-title":"Fetal liver development and implications for liver disease pathogenesis","volume":"20","author":"Lotto","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.cbi.2026.112275_bib23","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4161\/org.4.3.6849","article-title":"Early developmental influences on hepatic organogenesis","volume":"4","author":"Hyatt","year":"2008","journal-title":"Organogenesis"},{"key":"10.1016\/j.cbi.2026.112275_bib24","article-title":"Developmental programming of nonalcoholic fatty liver disease: the effect of early life nutrition on susceptibility and disease severity in later life","volume":"2015","author":"Li","year":"2015","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105231","article-title":"Integration of metabolomics and transcriptomics reveals short-chain chlorinated paraffin-induced hepatotoxicity in male Sprague-Dawley rat","volume":"133","author":"Geng","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbi.2026.112275_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141404","article-title":"Effect of short-chain chlorinated paraffins on metabolic profiling of male SD rats","volume":"750","author":"Geng","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112275_bib27","first-page":"11510","article-title":"Combined effects of dust and dietary exposure of occupational workers and local residents to Short- and medium-chain chlorinated paraffins in a mega E-Waste recycling industrial Park in south China","volume":"52","author":"Chen","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112275_bib28","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0976-0105.177703","article-title":"A simple practice guide for dose conversion between animals and human","volume":"7","author":"Nair","year":"2016","journal-title":"J. Basic Clin. Pharm."},{"key":"10.1016\/j.cbi.2026.112275_bib29","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1080\/026520300412555","article-title":"The use of safety or uncertainty factors in the setting of acute reference doses","volume":"17","author":"Renwick","year":"2000","journal-title":"Food Addit. Contam."},{"key":"10.1016\/j.cbi.2026.112275_bib30","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.cmet.2021.03.004","article-title":"Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health","volume":"33","author":"Kusuyama","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.cbi.2026.112275_bib31","article-title":"Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1\/2-PPARgamma-Cd36 pathway","volume":"42","author":"Li","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.cbi.2026.112275_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.119078","article-title":"From exposure to pathogenesis: a critical review of SCCPs-induced toxicity and potential molecular mechanisms","volume":"304","author":"Kou","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbi.2026.112275_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.111060","article-title":"Metabolomic mechanisms of short chain chlorinated paraffins toxicity in rats","volume":"197","author":"Yang","year":"2021","journal-title":"Environ. Res."},{"key":"10.1016\/j.cbi.2026.112275_bib34","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/(SICI)1520-7560(200003\/04)16:2<88::AID-DMRR81>3.0.CO;2-M","article-title":"Birth weight and the metabolic syndrome: thrifty phenotype or thrifty genotype?","volume":"16","author":"Stern","year":"2000","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.cbi.2026.112275_bib35","article-title":"Risk assessment of chlorinated paraffins in feed and food","volume":"18","author":"Schrenk","year":"2020","journal-title":"EFSA J"},{"key":"10.1016\/j.cbi.2026.112275_bib36","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.scitotenv.2017.11.304","article-title":"Developmental and metabolic responses of zebrafish (Danio rerio) embryos and larvae to short-chain chlorinated paraffins (SCCPs) exposure","volume":"622\u2013623","author":"Ren","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112275_bib37","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1001\/jama.2015.5370","article-title":"Nonalcoholic fatty liver disease: a systematic review","volume":"313","author":"Rinella","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.cbi.2026.112275_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.115102","article-title":"Targeting Wnt\/beta-catenin signaling to attenuate short-chain chlorinated paraffins-triggered hepatocyte mitochondrial fission and subsequent pyroptosis","volume":"161","author":"Xiao","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cbi.2026.112275_bib39","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3345\/cep.2023.00941","article-title":"Association between pre- and postnatal exposure to endocrine-disrupting chemicals and birth and neurodevelopmental outcomes: an extensive review","volume":"67","author":"Yesildemir","year":"2024","journal-title":"Clin. Exp. Pediatr."},{"key":"10.1016\/j.cbi.2026.112275_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147476","article-title":"Serum concentrations of per-\/polyfluoroalkyl substances and risk of type 2 diabetes: a case-control study","volume":"787","author":"Duan","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112275_bib41","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1210\/er.2011-1050","article-title":"Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses","volume":"33","author":"Vandenberg","year":"2012","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.cbi.2026.112275_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113366","article-title":"Prenatal exposure to diesel exhaust PM(2.5) programmed non-alcoholic fatty liver disease differently in adult male offspring of mice fed normal chow and a high-fat diet","volume":"255","author":"Wang","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112275_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.108945","article-title":"Gestational hypercholesterolemia programs hepatic steatosis in a sex-specific manner in ApoE-deficient mice","volume":"101","author":"Dumolt","year":"2022","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.cbi.2026.112275_bib44","doi-asserted-by":"crossref","first-page":"74","DOI":"10.4161\/adip.23320","article-title":"Metabolic impact of sex chromosomes","volume":"2","author":"Link","year":"2013","journal-title":"Adipocyte"},{"key":"10.1016\/j.cbi.2026.112275_bib45","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.molmed.2024.05.013","article-title":"Sexual dimorphism of metabolic dysfunction-associated steatotic liver disease","volume":"30","author":"Cherubini","year":"2024","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.cbi.2026.112275_bib46","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2025.13629","article-title":"Role of obesity and estrogen deficiency in non-alcoholic fatty liver disease: insights from a mouse model","volume":"32","author":"Afonso-Ali","year":"2025","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.cbi.2026.112275_bib47","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1152\/physrev.00029.2015","article-title":"Placental origins of chronic disease","volume":"96","author":"Burton","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbi.2026.112275_bib48","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/2042-6410-4-5","article-title":"Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics","volume":"4","author":"Gabory","year":"2013","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.cbi.2026.112275_bib49","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00018-018-2918-5","article-title":"Mechanisms for establishment of the placental glucocorticoid barrier, a guard for life","volume":"76","author":"Zhu","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cbi.2026.112275_bib50","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1210\/endrev\/bnae008","article-title":"The glucocorticoid receptor: isoforms, functions, and contribution to glucocorticoid sensitivity","volume":"45","author":"Lockett","year":"2024","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.cbi.2026.112275_bib51","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.earlhumdev.2017.09.011","article-title":"Sex differences in early-life programming of the hypothalamic-pituitary-adrenal axis in humans","volume":"114","author":"Gifford","year":"2017","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.cbi.2026.112275_bib52","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.toxlet.2020.05.035","article-title":"Reduced methylation of PP2Ac promotes ethanol-induced lipid accumulation through FOXO1 phosphorylation in vitro and in vivo","volume":"331","author":"Zhang","year":"2020","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.cbi.2026.112275_bib53","article-title":"Glycerol Kinase Drives Hepatic de novo Lipogenesis and Triglyceride Synthesis in Nonalcoholic Fatty Liver by Activating SREBP-1c Transcription, Upregulating DGAT1\/2 Expression, and Promoting Glycerol Metabolism","volume":"11","author":"Ouyang","year":"2024","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.cbi.2026.112275_bib54","doi-asserted-by":"crossref","first-page":"10978","DOI":"10.1021\/acs.est.9b03191","article-title":"Maternal polystyrene microplastic exposure during gestation and lactation altered metabolic homeostasis in the dams and their F1 and F2 offspring","volume":"53","author":"Luo","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112275_bib55","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.777","article-title":"MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease","volume":"12","author":"Luo","year":"2022","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.cbi.2026.112275_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138255","article-title":"Effects of polystyrene nanoplastic gestational exposure on mice","volume":"324","author":"Wang","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2026.112275_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2022.101193","article-title":"CD36 favours fat sensing and transport to govern lipid metabolism","volume":"88","author":"Li","year":"2022","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112275_bib58","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/toxsci\/kfac133","article-title":"2,3,7,8-Tetrachlorodibenzo-p-dioxin induces liver lipid metabolism disorder via the ROS\/AMPK\/CD36 signaling pathway","volume":"191","author":"Cong","year":"2023","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.cbi.2026.112275_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107935","article-title":"Palmitoylation-dependent modulation of CD36 trafficking and signaling integrates lipid uptake with metabolic disease pathogenesis","volume":"220","author":"Li","year":"2025","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.cbi.2026.112275_bib60","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.celrep.2018.12.022","article-title":"DHHC4 and DHHC5 facilitate fatty acid uptake by palmitoylating and targeting CD36 to the plasma membrane","volume":"26","author":"Wang","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.cbi.2026.112275_bib61","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/s42255-024-01036-5","article-title":"Inhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathy","volume":"6","author":"Wang","year":"2024","journal-title":"Nat. Metab."},{"key":"10.1016\/j.cbi.2026.112275_bib62","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1194\/jlr.R052902","article-title":"Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism","volume":"56","author":"Yen","year":"2015","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112275_bib63","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/j.bbalip.2012.08.002","article-title":"Triacylglycerol biosynthesis occurs via the glycerol-3-phosphate pathway in the insect Rhodnius prolixus","volume":"1821","author":"Alves-Bezerra","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbi.2026.112275_bib64","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1194\/jlr.M035493","article-title":"Intestine-specific expression of MOGAT2 partially restores metabolic efficiency in Mogat2-deficient mice","volume":"54","author":"Gao","year":"2013","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112275_bib65","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2508912122","article-title":"CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis","volume":"122","author":"Yang","year":"2025","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbi.2026.112275_bib66","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1194\/jlr.M700592-JLR200","article-title":"Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-\/- mice","volume":"49","author":"Nagle","year":"2008","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cbi.2026.112275_bib67","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1074\/mcp.M112.020230","article-title":"Protein correlation profiles identify lipid droplet proteins with high confidence","volume":"12","author":"Krahmer","year":"2013","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.cbi.2026.112275_bib68","doi-asserted-by":"crossref","first-page":"15112","DOI":"10.1074\/jbc.M115.649970","article-title":"Glycerol-3-phosphate Acyltransferase Isoform-4 (GPAT4) limits oxidation of exogenous fatty acids in brown adipocytes","volume":"290","author":"Cooper","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2026.112275_bib69","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s40200-015-0218-2","article-title":"The effects of PCB126 on intra-hepatic mechanisms associated with non alcoholic fatty liver disease","volume":"14","author":"Boucher","year":"2015","journal-title":"J. Diabetes Metab. Disord."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726003832?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726003832?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T04:27:08Z","timestamp":1788496028000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279726003832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":69,"alternative-id":["S0009279726003832"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112275","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gestational exposure to short-chain chlorinated paraffins induces sex-specific hepatic steatosis in adult mouse offspring","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112275","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112275"}}