{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:57:08Z","timestamp":1791233828073,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008638","name":"Environment and Climate Change Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008638","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.cbi.2026.112339","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:04:02Z","timestamp":1789225442000},"page":"112339","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification and characterization of covalent adduct formation of fluorotelomer unsaturated carboxylic acids with histone proteins"],"prefix":"10.1016","volume":"439","author":[{"given":"Shaogang","family":"Chu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8232-8565","authenticated-orcid":false,"given":"Robert J.","family":"Letcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbi.2026.112339_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132876","article-title":"Per- and polyfluorinated substances: an environmental update","volume":"291","author":"Falandysz","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2026.112339_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fenvs.2025.1559941","article-title":"Per- and polyfluoroalkyl substances (PFAS) in the cryosphere - occurrence, organismic accumulation, ecotoxicological impacts, transformation, and management strategies","volume":"13","author":"Arulananthan","year":"2025","journal-title":"Front. Environ. Sci."},{"key":"10.1016\/j.cbi.2026.112339_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.176274","article-title":"Cross-cutting studies of per- and polyfluorinated alkyl substances (PFAS) in Arctic wildlife and humans","volume":"954","author":"Lohmann","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112339_bib4","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1126\/science.abg9065","article-title":"Per- and polyfluoroalkyl substances in the environment","volume":"375","author":"Evich","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.cbi.2026.112339_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2025.154260","article-title":"Importance of post-translational protein modifications in PFAS toxicity","volume":"518","author":"Safreena","year":"2025","journal-title":"Toxicology"},{"key":"10.1016\/j.cbi.2026.112339_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143793","article-title":"A critical review of modeling poly- and perfluoroalkyl substances (PFAS) in the soil-water environment","volume":"757","author":"Sima","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbi.2026.112339_bib7","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1002\/etc.4890","article-title":"Per- and polyfluoroalkyl substance toxicity and human health review: current state of knowledge and strategies for informing future research","volume":"40","author":"Fenton","year":"2021","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib8","first-page":"159","article-title":"Poly- and per-fluoroalkyl substances toxicity on skeletal and cognitive well-being: a comprehensive review","volume":"43","author":"Roy","year":"2025","journal-title":"J. Environ. Sci. Health C"},{"key":"10.1016\/j.cbi.2026.112339_bib9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.trac.2019.05.017","article-title":"Characterization of the binding of per- and poly-fluorinated substances to proteins: a methodological review","volume":"116","author":"Liu","year":"2019","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib10","doi-asserted-by":"crossref","DOI":"10.1289\/EHP11814","article-title":"Environmental exposure to emerging alternatives of per- and polyfluoroalkyl substances and polycystic ovarian syndrome in women diagnosed with infertility: a mixture analysis","volume":"131","author":"Zhan","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.cbi.2026.112339_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115908","article-title":"Biotransformation of perfluoroalkyl acid precursors from various environmental systems: advances and perspectives","volume":"272","author":"Zhang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112339_bib12","doi-asserted-by":"crossref","first-page":"7974","DOI":"10.1021\/es200171y","article-title":"Is indirect exposure a significant contributor to the burden of perfluorinated acids observed in humans?","volume":"45","author":"D\u2019eon","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib13","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1021\/es049466y","article-title":"Aerobic biotransformation of 14C-labeled 8-2 telomer B alcohol by activated sludge from a domestic sewage treatment plant","volume":"39","author":"Wang","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib14","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1021\/es9028183","article-title":"Biodegradation of polyfluoroalkyl phosphates as a source of perfluorinated acids to the environment","volume":"44","author":"Lee","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113513","article-title":"Biotransformation of 6:2 fluorotelomer alcohol by the whole soybean (Glycine max L. Merrill) seedlings","volume":"257","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbi.2026.112339_bib16","doi-asserted-by":"crossref","first-page":"23613","DOI":"10.1007\/s11356-022-23901-0","article-title":"Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans","volume":"30","author":"Khan","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.cbi.2026.112339_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135510","article-title":"Biotransformation of 6:2\/4:2 fluorotelomer alcohols by Dietzia aurantiaca J3: enzymes and proteomics","volume":"478","author":"Bhardwaj","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbi.2026.112339_bib18","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1021\/es203978g","article-title":"Aerobic soil biodegradation of 8:2 fluorotelomer stearate monoester","volume":"46","author":"Dasu","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib19","doi-asserted-by":"crossref","first-page":"4799","DOI":"10.1021\/es070126x","article-title":"Production of perfluorinated carboxylic acids (PFCAs) from the biotransformation of polyfluoroalkyl phosphate surfactants (PAPS): exploring routes of human contamination","volume":"41","author":"D\u2019eon","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib20","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.chemosphere.2009.01.033","article-title":"8-2 Fluorotelomer alcohol aerobic soil biodegradation: pathways, metabolites, and metabolite .Pyields","volume":"75","author":"Wang","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbi.2026.112339_bib21","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.cbi.2009.03.015","article-title":"Kinetics of 8\u22122 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats","volume":"180","author":"Fasano","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2026.112339_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2024.117900","article-title":"Multi-adductomics: advancing mass spectrometry techniques for comprehensive exposome characterization","volume":"180","author":"Chao","year":"2024","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib23","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1021\/acs.chemrestox.3c00294","article-title":"Mass spectrometry-based strategies for assessing human exposure using hemoglobin adductomics","volume":"36","author":"Rajczewski","year":"2023","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib24","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.3390\/molecules27165252","article-title":"Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug detoxification and bioactivation","volume":"27","author":"Potega","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.cbi.2026.112339_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2023.117289","article-title":"Less is more: a new perspective for toxicity of emerging contaminants by structures, protein adducts and proteomics","volume":"167","author":"Hu","year":"2023","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2023.110460","article-title":"Review: organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates","volume":"376","author":"Lockridge","year":"2023","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2026.112339_bib27","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1007\/s00216-023-04925-y","article-title":"Analytical methods based on liquid chromatography for the analysis of albumin adducts involved in retrospective biomonitoring of exposure to mustard agents","volume":"416","author":"Avigo","year":"2024","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib28","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1021\/acs.chemrestox.6b00366","article-title":"Biomonitoring human albumin adducts: the past, the present, and the future","volume":"30","author":"Sabbioni","year":"2017","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib29","doi-asserted-by":"crossref","first-page":"13015","DOI":"10.1021\/acs.est.3c02930","article-title":"Querying the in vitro proteome cysteine reactivity of 8:2 fluorotelomer acrylate","volume":"57","author":"Hall","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib30","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1021\/cr5003529","article-title":"Histones: at the crossroads of peptide and protein chemistry","volume":"115","author":"M\u00fcller","year":"2015","journal-title":"Chem. Rev."},{"key":"10.1016\/j.cbi.2026.112339_bib31","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/38444","article-title":"Crystal structure of the nucleosome core particle at 2.8 angstrom resolution","volume":"389","author":"Luger","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2026.112339_bib32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.tibs.2020.05.009","article-title":"Nothing is yet set in (Hi)stone: novel post-translational modifications regulating chromatin function","volume":"45","author":"Chan","year":"2020","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cbi.2026.112339_bib33","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.tibs.2021.04.004","article-title":"Non-enzymatic covalent modifications as a new chapter in the histone code","volume":"46","author":"Maksimovic","year":"2021","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cbi.2026.112339_bib34","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1038\/nature05980","article-title":"Chromatin dynamics and the preservation of genetic information","volume":"447","author":"Downs","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.cbi.2026.112339_bib35","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1021\/acs.chemrestox.6b00379","article-title":"Histone adduction and its functional impact on epigenetics","volume":"30","author":"Galligan","year":"2017","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib36","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.cbpa.2021.05.002","article-title":"A chemical field guide to histone nonenzymatic modifications","volume":"63","author":"Faulkner","year":"2021","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.cbi.2026.112339_bib37","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s12038-020-00099-2","article-title":"Evaluation of post-translational modifications in histone proteins: a review on histone modification defects in developmental and neurological disorders","volume":"45","author":"Ramazi","year":"2020","journal-title":"J. Biosci."},{"key":"10.1016\/j.cbi.2026.112339_bib38","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.cbi.2005.06.007","article-title":"Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes","volume":"155","author":"Martin","year":"2005","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2026.112339_bib39","doi-asserted-by":"crossref","first-page":"7398","DOI":"10.1021\/es3008485","article-title":"In vitro interactions of biological nucleophiles with fluorotelomer unsaturated acids and aldehydes: fate and consequences","volume":"46","author":"Rand","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib40","first-page":"1655","article-title":"Covalent binding of fluorotelomer unsaturated aldehydes (FTUALs) and carboxylic acids (FTUCAs) to proteins","volume":"47","author":"Rand","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbi.2026.112339_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.202300650","article-title":"Combining SDS-PAGE to capillary zone electrophoresis-tandem mass spectrometry for high-resolution top-down proteomics analysis of intact histone proteoforms","volume":"24","author":"Fang","year":"2024","journal-title":"Proteomics"},{"key":"10.1016\/j.cbi.2026.112339_bib42","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1021\/ac303103b","article-title":"Data-dependent middle-down nano-liquid Chromatography-electron capture dissociation-tandem mass spectrometry: an application for the analysis of unfractionated histones","volume":"85","author":"Kalli","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2024.111095","article-title":"Covalent adduct formation of histone with organophosphorus pesticides in vitro","volume":"398","author":"Chu","year":"2024","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbi.2026.112339_bib44","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/pmic.201300256","article-title":"The top-down, middle-down, and bottom-up mass spectrometry approaches for characterization of histone variants and their post-translational modifications","volume":"14","author":"Moradian","year":"2014","journal-title":"Proteomics"},{"key":"10.1016\/j.cbi.2026.112339_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2022.109344","article-title":"Electrophile versus oxidant modification of cysteine residues: kinetics as a key driver of protein modification","volume":"727","author":"Sauerland","year":"2022","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cbi.2026.112339_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellin.2023.100090","article-title":"Molecular basis for protein histidine N1-specific methylation of the \u201cHis-x-His\u201d motifs by METTL9","volume":"2","author":"Zhao","year":"2023","journal-title":"Cell Insight"},{"key":"10.1016\/j.cbi.2026.112339_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2020.122503","article-title":"Identification and characterization of serum albumin covalent adduct formed with atrazine by liquid chromatography mass spectrometry","volume":"1163","author":"Chu","year":"2021","journal-title":"J. Chromatogr. B."},{"key":"10.1016\/j.cbi.2026.112339_bib48","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1002\/rcm.2086","article-title":"Characterization of adducts formed between human serum albumin and the butadiene metabolite epoxybutanediol","volume":"19","author":"Lindh","year":"2005","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.cbi.2026.112339_bib49","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1021\/tx4000107","article-title":"Detection of drug bioactivation in vivo: mechanism of nevirapine-albumin conjugate formation in patients","volume":"26","author":"Meng","year":"2013","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib50","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/1873-3468.70241","article-title":"The role of histone modifications in transcription regulation upon DNA damage","volume":"600","author":"Kolady","year":"2026","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cbi.2026.112339_bib51","doi-asserted-by":"crossref","first-page":"3575","DOI":"10.1042\/BCJ20210533","article-title":"The many ways that nature has exploited the unusual structural and chemical properties of phosphohistidine for use in proteins","volume":"478","author":"Kalagiri","year":"2021","journal-title":"Biochem. J."},{"key":"10.1016\/j.cbi.2026.112339_bib52","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.3390\/foods12234225","article-title":"Identification of protein-phenol adducts in meat proteins: a molecular probe technology study","volume":"12","author":"Yang","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.cbi.2026.112339_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2021.111556","article-title":"Binding of histidine and human serum albumin to dirhodium (II) tetraacetate","volume":"224","author":"Jalilehvand","year":"2021","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.cbi.2026.112339_bib54","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1021\/jf00046a005","article-title":"Modification of histidine residues in bovine serum albumin by reaction with (E)-2-octenal","volume":"42","author":"Alaiz","year":"1994","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib55","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.3390\/molecules26051349","article-title":"Covalent histone modification by an electrophilic derivative of the anti-HIV drug Nevirapine","volume":"26","author":"Harjivan","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.cbi.2026.112339_bib56","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1021\/acs.chemrestox.1c00172","article-title":"Chemical modifications induced by phthalic anhydride, a respiratory sensitizer, in reconstructed human epidermis: a combined HRMAS NMR and LC-MS\/MS proteomic approach","volume":"34","author":"Khong","year":"2021","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib57","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1039\/c3sc22294b","article-title":"Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents","volume":"4","author":"Meier","year":"2013","journal-title":"Chem. Sci."},{"key":"10.1016\/j.cbi.2026.112339_bib58","doi-asserted-by":"crossref","first-page":"42098","DOI":"10.1074\/jbc.M308167200","article-title":"A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4","volume":"278","author":"Oe","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbi.2026.112339_bib59","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1021\/tx00038a004","article-title":"Characterization of benzo[a]pyrene anti-diol epoxide adducts to human histones","volume":"7","author":"SooHoo","year":"1994","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib60","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/840518","article-title":"Mass spectrometry-based label-free quantitative proteomics","author":"Zhu","year":"2010","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.cbi.2026.112339_bib61","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/10408444.2022.2091423","article-title":"Critical review and analysis of literature on low dose exposure to chemical mixtures in mammalian in vivo systems","volume":"52","author":"Elcombe","year":"2022","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.cbi.2026.112339_bib62","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1042\/BCJ20250115","article-title":"Histone modification cross-talk: analytical tools and molecular mechanisms","volume":"483","author":"Jiang","year":"2026","journal-title":"Biochem. J."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726004473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726004473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:24:49Z","timestamp":1791231889000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279726004473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":62,"alternative-id":["S0009279726004473"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112339","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and characterization of covalent adduct formation of fluorotelomer unsaturated carboxylic acids with histone proteins","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112339","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2026 Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112339"}}