{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T02:23:17Z","timestamp":1794104597103,"version":"4.8.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32171124"],"award-info":[{"award-number":["32171124"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271180"],"award-info":[{"award-number":["32271180"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32471185"],"award-info":[{"award-number":["32471185"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971780"],"award-info":[{"award-number":["81971780"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31971101"],"award-info":[{"award-number":["31971101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemico-Biological Interactions"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.cbi.2026.112373","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:03:08Z","timestamp":1791558188000},"page":"112373","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Cytochrome P450 1A protects against hyperbaric oxygen-induced lung injury by regulating neutrophil extracellular trap formation"],"prefix":"10.1016","volume":"440","author":[{"given":"Yiting","family":"You","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingqian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochen","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7998-6444","authenticated-orcid":false,"given":"Xiaoyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5S","key":"10.1016\/j.cbi.2026.112373_bib1","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.1097\/SAP.0000000000003441","article-title":"Hyperbaric oxygen therapy for threatened nipple-sparing mastectomy flaps: an adjunct for flap salvage","volume":"90","author":"Nasr","year":"2023","journal-title":"Ann. Plast. Surg."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12010008","article-title":"Effectiveness of hyperbaric oxygen therapy in SARS-CoV-2 pneumonia: the primary results of a randomised clinical trial","volume":"12","author":"Siewiera","year":"2022","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib3","first-page":"1797","article-title":"Hyperbaric oxygen treatment reduced the lung injury of type II decompression sickness","volume":"8","author":"Geng","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"12","key":"10.1016\/j.cbi.2026.112373_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jstrokecerebrovasdis.2019.104403","article-title":"Cerebral air embolism after esophagogastroduodenoscopy: insight on pathophysiology, epidemiology, prevention and treatment","volume":"28","author":"Ghannam","year":"2019","journal-title":"J. Stroke Cerebrovasc. Dis."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib5","doi-asserted-by":"crossref","first-page":"L229","DOI":"10.1152\/ajplung.00450.2006","article-title":"Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide","volume":"293","author":"Demchenko","year":"2007","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"3","key":"10.1016\/j.cbi.2026.112373_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25031464","article-title":"A narrative review: the role of NETs in acute respiratory distress syndrome\/acute lung injury","volume":"25","author":"Zhou","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib7","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/s41420-023-01614-8","article-title":"Neutrophil extracellular traps contribute to immunothrombosis formation via the STING pathway in sepsis-associated lung injury","volume":"9","author":"Zhu","year":"2023","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.cbi.2026.112373_bib8","article-title":"Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury","volume":"6","author":"Liu","year":"2016","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.cbi.2026.112373_bib9","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1172\/JCI61303","article-title":"Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury","volume":"122","author":"Caudrillier","year":"2012","journal-title":"J. Clin. Investig."},{"issue":"26","key":"10.1016\/j.cbi.2026.112373_bib10","doi-asserted-by":"crossref","first-page":"6335","DOI":"10.1182\/blood-2012-01-405183","article-title":"Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice","volume":"119","author":"Thomas","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2026.112373_bib11","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3389\/fped.2020.00335","article-title":"Low-dose vitamin D protects hyperoxia-induced bronchopulmonary dysplasia by inhibiting neutrophil extracellular traps","volume":"8","author":"Chen","year":"2020","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.cbi.2026.112373_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1126516","article-title":"Neutrophil extracellular traps promote bronchopulmonary dysplasia-like injury in neonatal mice via the WNT\/beta-catenin pathway","volume":"13","author":"Sun","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bbrc.2019.11.041","article-title":"Heparin improves alveolarization and vascular development in hyperoxia-induced bronchopulmonary dysplasia by inhibiting neutrophil extracellular traps","volume":"522","author":"Sun","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib14","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.pharmthera.2012.12.007","article-title":"Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation","volume":"138","author":"Zanger","year":"2013","journal-title":"Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.cbi.2026.112373_bib15","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.freeradbiomed.2003.11.013","article-title":"Cyp1a2 protects against reactive oxygen production in mouse liver microsomes","volume":"36","author":"Shertzer","year":"2004","journal-title":"Free Radic. Biol. Med."},{"issue":"3","key":"10.1016\/j.cbi.2026.112373_bib16","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.taap.2004.01.018","article-title":"Mechanisms that regulate production of reactive oxygen species by cytochrome P450","volume":"199","author":"Zangar","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib17","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/toxsci\/kfu106","article-title":"Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress","volume":"141","author":"Lingappan","year":"2014","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib18","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/s41598-017-00516-x","article-title":"Role of cytochrome P450 (CYP)1A in Hyperoxic lung injury: analysis of the transcriptome and proteome","volume":"7","author":"Lingappan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbi.2026.112373_bib19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.freeradbiomed.2015.01.019","article-title":"Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury","volume":"82","author":"Wang","year":"2015","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.cbi.2026.112373_bib20","doi-asserted-by":"crossref","DOI":"10.1172\/JCI175031","article-title":"Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer","volume":"134","author":"Li","year":"2024","journal-title":"J. Clin. Investig."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib21","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s11658-024-00659-6","article-title":"The role of reactive oxygen species in severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection-induced cell death","volume":"29","author":"Xie","year":"2024","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.cbi.2026.112373_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2024.1474933","article-title":"Hyperbaric oxygen-induced acute lung injury: a mouse model study on pathogenic characteristics and recovery dynamics","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cbi.2026.112373_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/5213186","article-title":"\u03b2-Naphthoflavone-Induced mitochondrial respiratory damage in Cyp1 knockout Mouse and in cell culture systems: attenuation by resveratrol treatment","author":"Anandasadagopan","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.cbi.2026.112373_bib24","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.freeradbiomed.2020.07.027","article-title":"Oxygen-mediated lung injury in mice lacking the gene for NRF2: rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects","volume":"160","author":"Callaway","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbi.2026.112373_bib25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.freeradbiomed.2023.03.016","article-title":"Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells","volume":"202","author":"Meng","year":"2023","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.cbi.2026.112373_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2024.101153","article-title":"Inhibition of KLK8 promotes pulmonary endothelial repair by restoring the VE-cadherin\/Akt\/FOXM1 pathway","volume":"15","author":"Zhao","year":"2025","journal-title":"J. Pharm. Anal."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib27","doi-asserted-by":"crossref","first-page":"F138","DOI":"10.1152\/ajprenal.00052.2022","article-title":"Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy","volume":"324","author":"Noh","year":"2023","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.cbi.2026.112373_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102765","article-title":"EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25\/Keap1\/Nrf2 axis","volume":"63","author":"Zhang","year":"2023","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.cbi.2026.112373_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062563","article-title":"Hydrogen peroxide produced by oral Streptococci induces macrophage cell death","volume":"8","author":"Okahashi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cbi.2026.112373_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2026.104308","article-title":"The CYP1A-HSF1 axis alleviates mitochondrial oxidative stress to limit HBO-induced lung endothelial barrier damage","volume":"96","author":"Huang","year":"2026","journal-title":"Redox Biol."},{"key":"10.1016\/j.cbi.2026.112373_bib31","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.3389\/fpsyg.2017.01263","article-title":"Oxygen toxicity and special operations forces diving: hidden and dangerous","volume":"8","author":"Wingelaar","year":"2017","journal-title":"Front. Psychol."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1083\/jcb.200606027","article-title":"Novel cell death program leads to neutrophil extracellular traps","volume":"176","author":"Fuchs","year":"2007","journal-title":"J. Cell Biol."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib33","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1189\/jlb.5BT0615-234R","article-title":"At the Bedside: neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases","volume":"99","author":"Barnado","year":"2016","journal-title":"J. Leukoc. Biol."},{"issue":"16","key":"10.1016\/j.cbi.2026.112373_bib34","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1182\/blood-2013-07-516484","article-title":"Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation","volume":"123","author":"Rossaint","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.cbi.2026.112373_bib35","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8272504","article-title":"Neutrophil extracellular traps are pathogenic in ventilator-induced lung injury and partially dependent on TLR4","volume":"2017","author":"Li","year":"2017","journal-title":"Biomed Res. Int."},{"issue":"10","key":"10.1016\/j.cbi.2026.112373_bib36","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1182\/blood.2020007008","article-title":"Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome","volume":"136","author":"Middleton","year":"2020","journal-title":"Blood"},{"issue":"11","key":"10.1016\/j.cbi.2026.112373_bib37","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.138999","article-title":"Neutrophil extracellular traps in COVID-19","volume":"5","author":"Zuo","year":"2020","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.cbi.2026.112373_bib38","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.cell.2020.08.001","article-title":"Severe COVID-19 is marked by a dysregulated Myeloid cell compartment","volume":"182","author":"Schulte-Schrepping","year":"2020","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/cells10010151","article-title":"Significance of NETs Formation in COVID-19","volume":"10","author":"Janiuk","year":"2021","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.cbi.2026.112373_bib40","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20200652","article-title":"Targeting potential drivers of COVID-19: neutrophil extracellular traps","volume":"217","author":"Barnes","year":"2020","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib41","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12950-023-00329-y","article-title":"Neutrophil extracellular traps and pulmonary fibrosis: an update","volume":"20","author":"Yan","year":"2023","journal-title":"J. Inflamm."},{"issue":"6","key":"10.1016\/j.cbi.2026.112373_bib42","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1165\/rcmb.2019-0433OC","article-title":"PAD4 deficiency improves bleomycin-induced neutrophil extracellular traps and fibrosis in mouse lung","volume":"63","author":"Suzuki","year":"2020","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.cbi.2026.112373_bib43","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.tox.2015.01.019","article-title":"Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A","volume":"331","author":"Lingappan","year":"2015","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib44","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.taap.2013.06.007","article-title":"Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans","volume":"272","author":"Lingappan","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib45","first-page":"L287","article-title":"Simvastatin decreases hyperbaric oxygen-induced acute lung injury by upregulating eNOS","volume":"314","author":"Bao","year":"2018","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.cbi.2026.112373_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2022.105299","article-title":"Human genetic factors associated with pneumonia risk, a cue for COVID-19 susceptibility","volume":"102","author":"Guin","year":"2022","journal-title":"Infect. Genet. Evol."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib47","doi-asserted-by":"crossref","DOI":"10.1080\/13510002.2025.2550807","article-title":"Cytochrome P450 (CYP) 1 enzymes in acute lung injury: from molecular insights to therapeutic implications","volume":"30","author":"You","year":"2025","journal-title":"Redox Rep."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib48","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.taap.2011.06.018","article-title":"Prenatal administration of the cytochrome P4501A inducer, beta-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants","volume":"256","author":"Couroucli","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbi.2026.112373_bib49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.fct.2018.02.026","article-title":"Quercetin attenuates the hyperoxic lung injury in neonatal mice: implications for Bronchopulmonary dysplasia (BPD)","volume":"114","author":"Maturu","year":"2018","journal-title":"Food Chem. Toxicol."},{"issue":"4","key":"10.1016\/j.cbi.2026.112373_bib50","doi-asserted-by":"crossref","first-page":"L565","DOI":"10.1152\/ajplung.90487.2008","article-title":"Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia","volume":"296","author":"McGrath-Morrow","year":"2009","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"11","key":"10.1016\/j.cbi.2026.112373_bib51","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1096\/fj.03-1127fje","article-title":"The transcription factor NRF2 protects against pulmonary fibrosis","volume":"18","author":"Cho","year":"2004","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.cbi.2026.112373_bib52","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.bbrc.2018.04.161","article-title":"Nrf2 activation protects against intratracheal LPS induced mouse\/murine acute respiratory distress syndrome by regulating macrophage polarization","volume":"500","author":"Wei","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib53","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1084\/jem.20050538","article-title":"Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice","volume":"202","author":"Rangasamy","year":"2005","journal-title":"J. Exp. Med."},{"issue":"5","key":"10.1016\/j.cbi.2026.112373_bib54","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1165\/rcmb.2009-0054OC","article-title":"Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation","volume":"42","author":"Blake","year":"2010","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"9","key":"10.1016\/j.cbi.2026.112373_bib55","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1172\/JCI200421146","article-title":"Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice","volume":"114","author":"Rangasamy","year":"2004","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.cbi.2026.112373_bib56","article-title":"Zingerone inhibits the neutrophil extracellular trap formation and protects against sepsis via Nrf2-Mediated ROS inhibition","volume":"2022","author":"Zhu","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.cbi.2026.112373_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156254","article-title":"Guizhi Shaoyao Zhimu decoction inhibits neutrophil extracellular traps formation to relieve rheumatoid arthritis via gut microbial outer membrane vesicles","volume":"136","author":"Ye","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.cbi.2026.112373_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.115109","article-title":"Inhibition of MMP9 ameliorates neutrophil extracellular traps-mediated necroptosis through regulation of impaired autophagy in severe acute pancreatitis","volume":"162","author":"Zhang","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"6","key":"10.1016\/j.cbi.2026.112373_bib59","doi-asserted-by":"crossref","DOI":"10.1111\/1759-7714.70040","article-title":"Diosmetin inhibits NETs Formation in neutrophils through regulating Nrf2 signaling","volume":"16","author":"Guo","year":"2025","journal-title":"Thorac. Cancer"},{"issue":"1","key":"10.1016\/j.cbi.2026.112373_bib60","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1186\/s12951-024-02713-z","article-title":"Advancing osteoarthritis therapy with GMOCS hydrogel-loaded BMSCs-exos","volume":"22","author":"Zhou","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.cbi.2026.112373_bib61","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1194\/jlr.R800038-JLR200","article-title":"Arachidonic acid cytochrome P450 epoxygenase pathway","volume":"50","author":"Spector","year":"2009","journal-title":"J. Lipid Res."},{"issue":"2","key":"10.1016\/j.cbi.2026.112373_bib62","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/17425255.2021.1853705","article-title":"The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury","volume":"17","author":"Stading","year":"2021","journal-title":"Expert Opin. Drug Metab. Toxicol."}],"container-title":["Chemico-Biological Interactions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726004813?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009279726004813?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T01:26:04Z","timestamp":1794101164000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009279726004813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":62,"alternative-id":["S0009279726004813"],"URL":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112373","relation":{},"ISSN":["0009-2797"],"issn-type":[{"value":"0009-2797","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytochrome P450 1A protects against hyperbaric oxygen-induced lung injury by regulating neutrophil extracellular trap formation","name":"articletitle","label":"Article Title"},{"value":"Chemico-Biological Interactions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbi.2026.112373","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112373"}}