{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:24:06Z","timestamp":1791393846950,"version":"4.3.3"},"reference-count":76,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.cbpa.2011.04.014","type":"journal-article","created":{"date-parts":[[2011,5,9]],"date-time":"2011-05-09T23:16:53Z","timestamp":1304983013000},"page":"43-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Transient receptor potential vanilloid 4 in the European sea bass Dicentrarchus labrax: A candidate protein for osmosensing"],"prefix":"10.1016","volume":"160","author":[{"given":"Maryline","family":"Bossus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Charmantier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Lorin-Nebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpa.2011.04.014_bb0005","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0896-6273(03)00462-8","article-title":"Hypotonicity induces TRPV4-mediated nociception in rat","volume":"39","author":"Alessandri-Haber","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0010","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1074\/jbc.M511456200","article-title":"Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking","volume":"281","author":"Arniges","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0015","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/ar.1092330118","article-title":"The neuroepithelial cells of the fish gill filament: indolamine-immunocytochemistry and innervation","volume":"233","author":"Bailly","year":"1992","journal-title":"Anat. Rec."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0020","series-title":"Fish Adaptations","first-page":"179","article-title":"Osmoregulatory adaptations of freshwater teleosts","author":"Baldisserotto","year":"2003"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0025","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ejcb.2008.10.002","article-title":"Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation","volume":"88","author":"Becker","year":"2009","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0030","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0143-4160(03)00063-0","article-title":"TRPV channels as temperature sensors","volume":"33","author":"Benham","year":"2003","journal-title":"Cell Calcium"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0035","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.cbpa.2009.03.011","article-title":"Influence of salinity on the localization and expression of the CFTR chloride channel in the ionocytes of juvenile Dicentrarchus labrax exposed to seawater and freshwater","volume":"153","author":"Bodinier","year":"2009","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0040","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.cbpa.2010.06.185","article-title":"Ontogeny of osmoregulation and salinity tolerance in the gilthead sea bream Sparus aurata","volume":"157","author":"Bodinier","year":"2010","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0045","series-title":"Protein Methods","first-page":"415","article-title":"Gel electrophoresis under denaturing conditions","author":"Bollag","year":"1996"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0050","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.gene.2006.04.011","article-title":"A transcriptomic approach of salinity response in the euryhaline teleost, Dicentrarchus labrax","volume":"379","author":"Boutet","year":"2006","journal-title":"Gene"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0055","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0060","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1242\/jeb.02188","article-title":"Reciprocal expression of gill Na+\/K+-ATPase \u03b1-subunit isoforms \u03b11a and \u03b11b during seawater acclimation of three salmonid fishes that vary in their salinity tolerance","volume":"209","author":"Bystriansky","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0065","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","article-title":"The capsaicin receptor: a heat-activated ion channel in the pain pathway","volume":"389","author":"Caterina","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0070","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nature02196","article-title":"TRP channels as cellular sensors","volume":"426","author":"Clapham","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0075","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s00424-005-1456-9","article-title":"TRPV4 and the mammalian kidney","volume":"451","author":"Cohen","year":"2005","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0080","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nature03066","article-title":"TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells","volume":"432","author":"Corey","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0085","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1152\/physiolgenomics.2001.4.3.165","article-title":"Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2","volume":"4","author":"Delany","year":"2001","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0090","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.cub.2005.02.050","article-title":"Defective skeletogenesis with kidney stone formation in dwarf zebrafish mutant for trpm7","volume":"15","author":"Elizondo","year":"2005","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0095","series-title":"Osmotic and Ionic Regulation. Cells and Animals","author":"Evans","year":"2009"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0100","series-title":"The Physiology of Fishes","author":"Evans","year":"2006"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0105","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1152\/physrev.00050.2003","article-title":"The multifunctional fish gill: dominant site of gas exchange, osmoregulation, acid-base regulation, and excretion of nitrogenous waste","volume":"85","author":"Evans","year":"2005","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0110","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1111\/j.1095-8649.2010.02590.x","article-title":"Co-ordination of osmotic stress responses through osmosensing and signal transduction events in fishes","volume":"76","author":"Evans","year":"2010","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0115","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.vetpar.2003.09.020","article-title":"Validation of reference genes for transcription profiling in the salmon louse, Lepeaphtheirus salmonis, by quantitative real-time PCR","volume":"118","author":"Frost","year":"2003","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0120","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1440-169X.2006.00852.x","article-title":"Digestive tract ontogeny of Dicentrarchus labrax: implication in osmoregulation","volume":"48","author":"Giffard-Mena","year":"2006","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0125","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.cbpa.2008.04.004","article-title":"Adaptation of the sea-bass (Dicentrarchus labrax) to fresh water: role of aquaporins and Na+\/K+-ATPases","volume":"150","author":"Giffard-Mena","year":"2008","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0130","series-title":"The Physiology of Fishes","first-page":"85","article-title":"Aquatic and aerial respiration","author":"Graham","year":"2006"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0135","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1242\/jcs.01675","article-title":"Homo- and heteromeric assembly of TRPV channel subunits","volume":"118","author":"Hellwig","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0140","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1152\/physrev.00037.2007","article-title":"Physiology of cell volume regulation in vertebrates","volume":"89","author":"Hoffmann","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0145","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1242\/jeb.01564","article-title":"Development of oxygen sensing in the gills of zebrafish","volume":"208","author":"Jonz","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0150","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1083\/jcb.200805124","article-title":"TRPP2 and TRPV4 form a polymodal sensory channel complex","volume":"182","author":"K\u00f6ttgen","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0155","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.ajhg.2009.01.021","article-title":"Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia","volume":"84","author":"Krakow","year":"2009","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0160","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.1111\/j.1742-4658.2007.06097.x","article-title":"Osmotic stress sensing and signaling in animals","volume":"274","author":"K\u00fcltz","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0165","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.aquaculture.2005.05.021","article-title":"Growth performance of gilthead sea bream Sparus aurata in different osmotic conditions: implications for osmoregulation and energy metabolism","volume":"250","author":"Laiz-Carri\u00f3n","year":"2005","journal-title":"Aquaculture"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0170","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/S1063-4584(08)60052-7","article-title":"Functional characterization of TRPV4 as an osmotically sensitive ion channel in articular chondrocytes","volume":"16","author":"Leddy","year":"2008","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0175","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1113\/expphysiol.2006.035642","article-title":"Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals","volume":"92","author":"Liedtke","year":"2007","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0180","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0092-8674(00)00143-4","article-title":"Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor","volume":"103","author":"Liedtke","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0185","doi-asserted-by":"crossref","first-page":"13698","DOI":"10.1073\/pnas.1735416100","article-title":"Abnormal osmotic regulation in trpv4\u2212\/\u2212 mice","volume":"100","author":"Liedtke","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0190","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1095-6433(03)00136-3","article-title":"The expression of gill Na, K-ATPase in milkfish, Chanos chanos, acclimated to seawater, brackish water and fresh water","volume":"135","author":"Lin","year":"2003","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0195","doi-asserted-by":"crossref","first-page":"15485","DOI":"10.1074\/jbc.M600549200","article-title":"A Role for AQP5 in activation of TRPV4 by hypotonicity","volume":"281","author":"Liu","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0200","doi-asserted-by":"crossref","first-page":"12611","DOI":"10.1073\/pnas.0803970105","article-title":"TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells","volume":"105","author":"Lorenzo","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0205","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.cbpa.2008.01.037","article-title":"Extracellular calcium-sensing receptors in fishes","volume":"149","author":"Loretz","year":"2008","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0210","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ygcen.2008.12.020","article-title":"Extracellular calcium-sensing receptor distribution in osmoregulatory and endocrine tissues of the tilapia","volume":"161","author":"Loretz","year":"2009","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0215","doi-asserted-by":"crossref","first-page":"4908","DOI":"10.1242\/jeb.02591","article-title":"The Na+\/K+\/2Cl\u2212 cotransporter in the sea bass Dicentrarchus labrax during ontogeny: involvement in osmoregulation","volume":"209","author":"Lorin-Nebel","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0220","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.modgep.2006.10.011","article-title":"Dynamic expression of the osmosensory channel trpv4 in multiple developing organs in zebrafish","volume":"7","author":"Mangos","year":"2007","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0225","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1006\/gcen.2001.7746","article-title":"The role of prolactin in fish osmoregulation: a review","volume":"125","author":"Manzon","year":"2002","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0230","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1242\/jeb.205.9.1265","article-title":"Redistribution of immunofluorescence of CFTR anion channel and NKCC cotransporter in chloride cells during adaptation of the killifish Fundulus heteroclitus to sea water","volume":"205","author":"Marshall","year":"2002","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0235","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.cmet.2008.08.002","article-title":"TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts","volume":"8","author":"Masuyama","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0240","doi-asserted-by":"crossref","first-page":"32158","DOI":"10.1074\/jbc.M706158200","article-title":"Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation","volume":"282","author":"Muramatsu","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0245","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00429-004-0438-6","article-title":"Morphofunctional ontogeny of the urinary system of the European sea bass Dicentrarchus labrax","volume":"209","author":"Nebel","year":"2005","journal-title":"Anat. Embryol. Berl."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0250","doi-asserted-by":"crossref","first-page":"3859","DOI":"10.1242\/jeb.01853","article-title":"Differential freshwater adaptation in juvenile sea-bass Dicentrarchus labrax: involvement of gills and urinary system","volume":"208","author":"Nebel","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0255","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.modgep.2006.01.005","article-title":"The Na+\/PO4 cotransporter SLC20A1 gene labels distinct restricted subdomains of the developing pronephros in Xenopus and zebrafish embryos","volume":"6","author":"Nichane","year":"2006","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00424-005-1462-y","article-title":"TRP channels: a TR(I)P through a world of multifunctional cation channels","volume":"451","author":"Nilius","year":"2005","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0265","doi-asserted-by":"crossref","first-page":"C195","DOI":"10.1152\/ajpcell.00365.2003","article-title":"TRPV4 calcium entry channel: a paradigm for gating diversity","volume":"286","author":"Nilius","year":"2004","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0270","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00424-005-1424-4","article-title":"The mechanosensitive nature of TRPV channels","volume":"451","author":"O\u2018Neil","year":"2005","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0275","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ceca.2005.06.028","article-title":"TRP channels: an overview","volume":"38","author":"Pedersen","year":"2005","journal-title":"Cell Calcium"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0280","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.gene.2004.07.041","article-title":"Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes","volume":"342","author":"Qiu","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0285","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s00424-009-0681-z","article-title":"Novel regulatory aspects of the extracellular Ca2+-sensing receptor","volume":"458","author":"Riccardi","year":"2009","journal-title":"CaR. Pfl\u00fcgers Arch."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0290","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.bbaexp.2005.05.012","article-title":"Molecular cloning of a molluscan gonatropin-releasing hormone receptor orthologue specifically expressed in the gonad","volume":"1730","author":"Rodet","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0295","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.1523\/JNEUROSCI.0679-05.2005","article-title":"Mutually exclusive glomerular innervation by two distinct types of olfactory sensory neurons revealed in transgenic zebrafish","volume":"25","author":"Sato","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0300","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ygcen.2005.09.006","article-title":"Disparate release of prolactin and growth hormone from the tilapia pituitary in response to osmotic stimulation","volume":"145","author":"Seale","year":"2006","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0305","doi-asserted-by":"crossref","first-page":"C1290","DOI":"10.1152\/ajpcell.00532.2002","article-title":"Evidence that signal transduction for osmoreception is mediated by stretch-activated ion channels in tilapia","volume":"284","author":"Seale","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0310","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1242\/jeb.02190","article-title":"Characterization of a branchial epithelial calcium channel (ECaC) in freshwater rainbow trout (Oncorhynchus mykiss)","volume":"209","author":"Shahsavarani","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0315","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1126\/science.1084370","article-title":"NompC TRP channel required for vertebrate sensory hair cell mechanotransduction","volume":"301","author":"Sidi","year":"2003","journal-title":"Sci."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0320","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/35036318","article-title":"OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity","volume":"2","author":"Strotmann","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0325","doi-asserted-by":"crossref","first-page":"4347","DOI":"10.1016\/S0021-9258(18)68932-X","article-title":"Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump","volume":"263","author":"Takeyasu","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0330","doi-asserted-by":"crossref","first-page":"F17","DOI":"10.1152\/ajprenal.00397.2003","article-title":"Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments","volume":"287","author":"Tian","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0335","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.cbpb.2005.01.013","article-title":"Ontogeny of osmoregulation in postembryonic fish: a review","volume":"141","author":"Varsamos","year":"2005","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0340","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1677\/joe.1.06847","article-title":"Pituitary hormone mRNA expression in European sea bass Dicentrarchus labrax in seawater and following acclimation to fresh water","volume":"191","author":"Varsamos","year":"2006","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0345","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1146\/annurev.biochem.75.103004.142819","article-title":"TRP channels","volume":"76","author":"Venkatachalam","year":"2007","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0350","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.neuroscience.2010.03.042","article-title":"Brain volume regulation in response to changes in osmolality","volume":"168","author":"Verbalis","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0355","series-title":"49th Annual Meeting of the Orthopaedic Research Society","article-title":"TRPV4, a novel vanilloid receptor-like ion channel is highly expressed in chondrocytes and functions to attenuate chondrocyte responses to catabolic stimuli","author":"Votta","year":"2003"},{"key":"10.1016\/j.cbpa.2011.04.014_bb0360","doi-asserted-by":"crossref","first-page":"36561","DOI":"10.1074\/jbc.M703903200","article-title":"OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum","volume":"282","author":"Wang","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0365","doi-asserted-by":"crossref","first-page":"R446","DOI":"10.1152\/ajpregu.90435.2008","article-title":"Osmosensitivity of prolactin cells is enhanced by the water channel aquaporin-3 in a euryhaline Mozambique tilapia (Oreochromis mossambicus)","volume":"296","author":"Watanabe","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0370","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0014-5793(00)02212-2","article-title":"Trp12, a novel Trp related protein from kidney","volume":"485","author":"Wissenbach","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0375","doi-asserted-by":"crossref","first-page":"F1103","DOI":"10.1152\/ajprenal.00245.2005","article-title":"Glycosylation of the osmoresponsive transient receptor potential channel TRPV4 on Asn-651 influences membrane trafficking","volume":"290","author":"Xu","year":"2006","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.cbpa.2011.04.014_bb0380","doi-asserted-by":"crossref","first-page":"11520","DOI":"10.1074\/jbc.M211061200","article-title":"Regulation of a Transient Receptor Potential (TRP) channel by tyrosine phosphorylation","volume":"278","author":"Xu","year":"2003","journal-title":"J. Biol. Chem."}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643311001267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643311001267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:09:27Z","timestamp":1761084567000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643311001267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":76,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S1095643311001267"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2011.04.014","relation":{},"ISSN":["1095-6433"],"issn-type":[{"value":"1095-6433","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transient receptor potential vanilloid 4 in the European sea bass Dicentrarchus labrax: A candidate protein for osmosensing","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2011.04.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}