{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T02:45:45Z","timestamp":1781232345981,"version":"3.54.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NSERC Discovery","award":["RGPIN 3698-2009"],"award-info":[{"award-number":["RGPIN 3698-2009"]}]},{"DOI":"10.13039\/501100004190","name":"NSF","doi-asserted-by":"publisher","award":["OCE-1314567"],"award-info":[{"award-number":["OCE-1314567"]}],"id":[{"id":"10.13039\/501100004190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004190","name":"NSF","doi-asserted-by":"publisher","award":["DEB-1120512"],"award-info":[{"award-number":["DEB-1120512"]}],"id":[{"id":"10.13039\/501100004190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.cbpa.2014.11.010","type":"journal-article","created":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T16:31:25Z","timestamp":1416241885000},"page":"68-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Cold acclimation allows regulation of chloride secretion in a eurythermic teleost fish Fundulus heteroclitus"],"prefix":"10.1016","volume":"180","author":[{"given":"Alicia M.","family":"Malone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina R.F.","family":"Cozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpa.2014.11.010_bb0005","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.cbpa.2013.11.004","article-title":"Cold acclimation of NaCl secretion in a eurythermic teleost: mitochondrial function and gill remodeling","volume":"168","author":"Barnes","year":"2013","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00300-006-0165-y","article-title":"Temperature-dependent energy allocation to growth in Antarctic and boreal eelpout (Zoarcidae)","volume":"30","author":"Brodte","year":"2006","journal-title":"Polar Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0015","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.cbpa.2012.03.010","article-title":"Control of ion transport by mitochondrion-rich chloride cells of eurythermic teleost fish: Cold shock vs. cold acclimation","volume":"162","author":"Buhariwalla","year":"2012","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0020","first-page":"257","article-title":"Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics","volume":"2","author":"Burnett","year":"2007","journal-title":"Comp. Biochem. Physiol. D: Genomics Proteomics"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0025","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s00360-012-0685-4","article-title":"Water absorption and bicarbonate secretion in the intestine of the sea bream are regulated by transmembrane and soluble adenylyl cyclase stimulation","volume":"182","author":"Carvalho","year":"2012","journal-title":"J. Comp. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0030","doi-asserted-by":"crossref","first-page":"11304","DOI":"10.1016\/S0021-9258(18)82125-1","article-title":"Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all ten PKA consensus phosphorylation sites","volume":"268","author":"Chang","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0035","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/0092-8674(91)90446-6","article-title":"Phosphorylation of the R-domain by cAMP-dependent protein kinase regulates the CFTR chloride channel","volume":"66","author":"Cheng","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0040","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF00762215","article-title":"The adaptation of biological membranes to temperature and pressure: fish from the deep and cold","volume":"21","author":"Cossins","year":"1989","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0275","series-title":"Biochemistry and molecular biology of fishes","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1873-0140(06)80032-9","article-title":"Effects of temperature on cellular ion regulation and membrane transport systems","volume":"vol. 15","author":"Cossins","year":"1995"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0050","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1113\/jphysiol.1977.sp011995","article-title":"Active chloride transport in the in vitro opercular skin of a teleost (Fundulus heteroclitus), a gill-like epithelium rich in chloride cells","volume":"271","author":"Degnan","year":"1977","journal-title":"J. Physiol. Lond."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0055","doi-asserted-by":"crossref","DOI":"10.1152\/ajpregu.90337.2008","article-title":"Teleost fish osmoregulation: what have we learned since August Krogh, Homer Smith, and Ancel Keys","volume":"295","author":"Evans","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0060","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1152\/physiolgenomics.90266.2008","article-title":"Ancient and modern duplication events and the evolution of stearoyl-CoA desaturases in teleost fishes","volume":"35","author":"Evans","year":"2008","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0065","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1242\/jeb.024034","article-title":"Do mitochondrial properties explain intraspecific variation in thermal tolerance?","volume":"212","author":"Fangue","year":"2009","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0070","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S1040-7952(99)80006-8","article-title":"Regulation of CFTR Cl\u2212 ion channels by phosphorylation and dephosphorylation","volume":"33","author":"Gadsby","year":"1999","journal-title":"Adv. Second Messenger Phosphoprotein Res."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0075","doi-asserted-by":"crossref","first-page":"16970","DOI":"10.1073\/pnas.0403627101","article-title":"Coping with cold: an integrative, multitissue analysis of the transcriptome of a poikilothermic vertebrate","volume":"101","author":"Gracey","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0080","doi-asserted-by":"crossref","first-page":"319","DOI":"10.2307\/1442526","article-title":"Environment and salinity tolerance in the genus Fundulus","volume":"2","author":"Griffith","year":"1974","journal-title":"Copeia"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0085","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S1464793103006328","article-title":"Metabolic responses to low temperature in fish muscle","volume":"79","author":"Guderley","year":"2004","journal-title":"Biol. Rev."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0090","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S1074-5521(00)90061-9","article-title":"New fluorescent probes for the measurement of cell membrane viscosity","volume":"8","author":"Haidekker","year":"2002","journal-title":"Chem. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0095","first-page":"19","article-title":"Thermal adaptation in biological-membranes \u2014 is homeoviscous adaptation the explanation?","volume":"57","author":"Hazel","year":"1995","journal-title":"Annu. Rev. Plant Physiol. Plant Mol. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0100","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1006\/cryo.2000.2252","article-title":"Purification and characterization of protein kinase A from liver of the freeze tolerant wood frog: Role in glycogenolysis during freezing","volume":"40","author":"Holden","year":"2000","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/jeb.201.1.1","article-title":"Latitudinal variation in the abundance and oxidative capacities of muscle mitochondria in perciform fishes","volume":"201","author":"Johnston","year":"1998","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0110","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1165\/ajrcmb.13.6.7576703","article-title":"CFTR-mediated chloride permeability is regulated by type-III phosphodiesterases in airway epithelial cells","volume":"13","author":"Kelley","year":"1995","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0115","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1113\/jphysiol.2002.036806","article-title":"Regulation of Cl\u2212 secretion by \u03b1-adrenergic receptors in mouse colonic epithelium","volume":"548","author":"Lam","year":"2003","journal-title":"J. Physiol. Lond."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0280","series-title":"The Structure of biological membranes","first-page":"73","article-title":"The mesomorphic phase behavior of lipid bilayers","author":"Lewis","year":"1991"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0125","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.cell.2007.09.037","article-title":"Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia","volume":"131","author":"Li","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0130","doi-asserted-by":"crossref","first-page":"27086","DOI":"10.1074\/jbc.M702019200","article-title":"Protein kinase C phosphorylation disrupts Na+\/H+ exchanger regulatory factor 1 autoinhibition and promotes cystic fibrosis transmembrane conductance regulator macromolecular assembly","volume":"282","author":"Li","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0135","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1242\/jeb.00884","article-title":"Effect of beta-adrenergic stimulation on the relationship between membrane potential, intracellular [Ca2+] and sarcoplasmic reticulum Ca2+ uptake in rainbow trout atrial myocytes","volume":"207","author":"Llach","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0140","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/jez.10127","article-title":"Na+, Cl\u2212, Ca2+ and Zn2+ transport by fish gills: retrospective review and prospective synthesis","volume":"293","author":"Marshall","year":"2002","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0145","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.bbamem.2003.10.015","article-title":"Rapid regulation of NaCl secretion by estuarine teleost fish: Coping strategies for short duration fresh water exposures","volume":"1618","author":"Marshall","year":"2003","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0285","series-title":"Euryhaline Fish, Fish Physiology","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/B978-0-12-396951-4.00008-6","article-title":"Osmoregulation in estuarine fish","volume":"Vol. 32","author":"Marshall","year":"2013"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0175","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0005-2736(02)00584-9","article-title":"Cystic fibrosis transmembrane conductance regulator in teleost fish","volume":"1566","author":"Marshall","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0160","doi-asserted-by":"crossref","first-page":"5504","DOI":"10.1073\/pnas.90.12.5504","article-title":"Alpha-2-adrenergic inhibition of Cl\u2212 transport by opercular epithelium is mediated by intracellular Ca2+","volume":"90","author":"Marshall","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0165","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1242\/jeb.201.12.1959","article-title":"Neural modulation of salt secretion in teleost opercular epithelium by \u03b12-adrenergic receptors and inositol 1,4,5-trisphosphate","volume":"201","author":"Marshall","year":"1998","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0155","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1242\/jeb.203.12.1897","article-title":"Control of epithelial Cl\u2212 secretion by basolateral osmolality in the euryhaline teleost Fundulus heteroclitus","volume":"203","author":"Marshall","year":"2000","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0170","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1242\/jeb.01491","article-title":"Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium","volume":"208","author":"Marshall","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0180","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1242\/jeb.030015","article-title":"CFTR Cl\u2212 channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish","volume":"212","author":"Marshall","year":"2009","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0185","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF00695772","article-title":"Converging adrenergic and cholinergic mechanisms in the inhibition of Cl\u2212 secretion in fish opercular epithelium","volume":"154","author":"May","year":"1985","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0190","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/B978-0-444-82033-4.50026-X","article-title":"Opercular membranes and skin","volume":"3","author":"McCormick","year":"1994","journal-title":"J. Biochem. Mol. Biol. Fish."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0195","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1242\/jeb.203.3.631","article-title":"Does membrane fluidity contribute to thermal compensation of beta-adrenergic signal transduction in isolated trout hepatocytes?","volume":"203","author":"McKinley","year":"2000","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0200","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1161\/01.RES.0000134629.84732.11","article-title":"Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases","volume":"95","author":"Mongillo","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0210","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.ne.12.030189.000435","article-title":"Structure of the adrenergic and related receptors","volume":"12","author":"O'Dowd","year":"1989","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0205","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1242\/jeb.046854","article-title":"Mitochondrial biogenesis in cold-bodied fishes","volume":"214","author":"O'Brien","year":"2011","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0215","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1242\/jeb.01016","article-title":"Changes in gene expression associated with acclimation to constant temperatures and fluctuating daily temperatures in an annual killifish Austrofundulus limnaeus","volume":"207","author":"Podrabsky","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0220","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1098\/rstb.2006.1947","article-title":"Thermal limits and adaptation in marine Antarctic ectotherms: an integrative view","volume":"362","author":"P\u00f6rtner","year":"2007","journal-title":"Philos. Trans. R. Soc. B-Biol. Sci."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0225","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1002\/jps.2600721105","article-title":"Analysis of monobutyryl and dibutyryl derivatives of adenosine 3\u2032,5\u2032-monophosphate in biological samples using isocratic ion pair high-performance liquid chromatography","volume":"72","author":"Schaeffer","year":"1983","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0230","doi-asserted-by":"crossref","first-page":"C715","DOI":"10.1152\/ajpcell.1998.274.3.C715","article-title":"A divergent CFTR homologue: highly regulated salt transport in the euryhaline teleost F-heteroclitus","volume":"274","author":"Singer","year":"1998","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0235","series-title":"Physiology of Membrane Disorders","first-page":"25","article-title":"Composition and dynamics of lipids in membranes","author":"Thompson","year":"1986"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0240","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.brainres.2004.04.025","article-title":"Alpha2-adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons","volume":"1014","author":"Timmons","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0245","first-page":"R61","article-title":"Modulation of NaCl absorption by [HCO3\u2212] in the marine teleost intestine is mediated by soluble adenylyl cyclase","volume":"299","author":"Tresguerres","year":"2010","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0250","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/BF00389800","article-title":"Restructuring of plasma membrane phospholipids in isolated hepatocytes of rainbow trout during brief in vitro cold exposure","volume":"164","author":"Williams","year":"1995","journal-title":"J. Comp. Physiol. B Biochem. Syst. Environ. Physiol."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0255","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0005-2736(91)90321-X","article-title":"Rapid cold-induced changes of membrane order and \u0394-9-desaturase activity in endoplasmic reticulum of carp liver: a time course study of thermal acclimation","volume":"1064","author":"Wodtke","year":"1991","journal-title":"Biochim. Biophys. Acta"},{"issue":"6","key":"10.1016\/j.cbpa.2014.11.010_bb0260","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1111\/j.1471-4159.1988.tb01162.x","article-title":"Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate","volume":"51","author":"Yusta","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cbpa.2014.11.010_bb0265","first-page":"1171","article-title":"Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes","volume":"5560","author":"Zaccolo","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.cbpa.2014.11.010_bb0270","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1111\/j.1749-7345.2010.00422.x","article-title":"Transcriptional response of \u0394-9-desaturase gene to acute and chronic cold stress in nile tilapia, Oreochromis niloticus","volume":"41","author":"Zerai","year":"2010","journal-title":"J. World Aquacult. Soc."}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643314002281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643314002281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T18:17:42Z","timestamp":1650651462000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643314002281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":54,"alternative-id":["S1095643314002281"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2014.11.010","relation":{},"ISSN":["1095-6433"],"issn-type":[{"value":"1095-6433","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cold acclimation allows regulation of chloride secretion in a eurythermic teleost fish Fundulus heteroclitus","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2014.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}