{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:10:32Z","timestamp":1788408632329,"version":"build-2803163510"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003069","name":"Instituto Polit\u00e9cnico Nacional-SIP","doi-asserted-by":"crossref","award":["20150855"],"award-info":[{"award-number":["20150855"]}],"id":[{"id":"10.13039\/501100003069","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.cbpa.2016.05.006","type":"journal-article","created":{"date-parts":[[2016,5,7]],"date-time":"2016-05-07T19:26:17Z","timestamp":1462649177000},"page":"35-46","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Usefulness of oxidative stress biomarkers evaluated in the snout scraping, serum and Peripheral Blood Cells of Crocodylus moreletii from Southeast Campeche for assessment of the toxic impact of PAHs, metals and total phenols"],"prefix":"10.1016","volume":"200","author":[{"given":"Ricardo","family":"Dzul-Caamal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Hern\u00e1ndez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio","family":"Gonzalez-J\u00e1uregui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio E.","family":"Padilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel Ivan","family":"Gir\u00f3n-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Vega-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpa.2016.05.006_bb0005","series-title":"Standard Methods for the Examination of Water and Wastewater","first-page":"3.17","article-title":"Metals by flame atomic absorption","author":"APHA (American Public Health Association","year":"1998"},{"issue":"6","key":"10.1016\/j.cbpa.2016.05.006_bb0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130002","article-title":"Biotransformation and oxidative stress responses in captive Nile crocodile (Crocodylus niloticus) exposed to organic contaminants from the natural environment in South Africa","volume":"10","author":"Arukwe","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0015","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"Microsomal lipid peroxidation","volume":"52","author":"Buege","year":"1978","journal-title":"Methods Enzymol."},{"issue":"2","key":"10.1016\/j.cbpa.2016.05.006_bb0020","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00244-014-0088-5","article-title":"Metals and metallothioneins in Morelet's crocodile (Crocodylus moreletii) from a transboundary river between Mexico and Belize","volume":"68","author":"Buenfil-Rojas","year":"2015","journal-title":"Arch. Environ. Contam. Toxicol."},{"issue":"4","key":"10.1016\/j.cbpa.2016.05.006_bb0025","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s002440010066","article-title":"Metals and metalloids in tissues of American alligators in three Florida lakes","volume":"38","author":"Burger","year":"2000","journal-title":"Arch. Environ. Contam. Toxicol."},{"issue":"4","key":"10.1016\/j.cbpa.2016.05.006_bb0030","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.7589\/0090-3558-46.4.1234","article-title":"Heavy metal and selenium concentrations in liver tissue from wild American alligator (Alligator mississippiensis) livers near Charleston, South Carolina","volume":"46","author":"Campbell","year":"2010","journal-title":"J. Wildl. Dis."},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0035","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1086\/physzool.46.1.30152518","article-title":"Integumentary permeability to water in Caiman crocodilus and Crocodylus niloticus (Crocodilia: Reptilia)","volume":"46","author":"Diefenbach","year":"1973","journal-title":"Physiol. Zool."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0040","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ecoenv.2012.07.008","article-title":"Implications of cytochrome 450 isoenzymes, aryl-esterase and oxonase activity in the inhibition of the acetylcholinesterase of Chirostoma jordani treated with phosphorothionate pesticides","volume":"84","author":"Dzul-Caamal","year":"2012","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0045","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.cbpa.2013.03.005","article-title":"Pro-oxidant and antioxidant response elicited by CH2Cl2, CHCl3 and BrCHCl2 in Goodea gracilis using non-invasive methods","volume":"165","author":"Dzul-Caamal","year":"2013","journal-title":"Comp. Biochem. Physiol. A"},{"issue":"2016","key":"10.1016\/j.cbpa.2016.05.006_bb0050","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.ecolind.2015.09.017","article-title":"Multivariate analysis of biochemical responses using non-invasive methods to evaluate the health status of the endangered blackfin goodeid (Girardinichthys viviparus)","volume":"60","author":"Dzul-Caamal","year":"2016","journal-title":"Ecol. Indic."},{"issue":"9","key":"10.1016\/j.cbpa.2016.05.006_bb0055","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S0006-2952(98)00003-3","article-title":"Induction time course of cytochromes P450 by phenobarbital and 3-methylcholanthrene pretreatment in liver microsomes of Alligator mississippiensis","volume":"55","author":"Ertl","year":"1998","journal-title":"Biochem. Pharmacol."},{"issue":"1\u20132","key":"10.1016\/j.cbpa.2016.05.006_bb0060","first-page":"241","article-title":"Selected oxidative stress markers in a South American crocodilian species","volume":"146","author":"Furtado-Filho","year":"2007","journal-title":"Comp. Biochem. Physiol. C"},{"issue":"3","key":"10.1016\/j.cbpa.2016.05.006_bb0065","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00244-011-9716-5","article-title":"Persistent organic contaminants and steroid hormones levels in Morelet's crocodiles from the Southern Gulf of Mexico","volume":"62","author":"Gonzalez-Jauregui","year":"2012","journal-title":"Arch. Environ. Contam. Toxicol."},{"issue":"3","key":"10.1016\/j.cbpa.2016.05.006_bb0070","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/s00244-003-0234-y","article-title":"Experimental study of blood lead kinetics in estuarine crocodiles (Crocodylus porosus) exposed to ingested lead shot","volume":"45","author":"Hammerton","year":"2003","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0075","series-title":"Functional Metabolism: Regulation and Adaptation","first-page":"319","article-title":"Oxygen in biology and biochemistry: role of free radicals","author":"Hermes-Lima","year":"2004"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0080","series-title":"Functional Metabolism: Regulation and Adaptation","first-page":"369","article-title":"Oxidative Stress and Medical Science","author":"Hermes-Lima","year":"2004"},{"issue":"4","key":"10.1016\/j.cbpa.2016.05.006_bb0085","first-page":"537","article-title":"Animal response to drastic changes in oxygen availability and physiological oxidative stress","volume":"133","author":"Hermes-Lima","year":"2002","journal-title":"Comp. Biochem. Physiol. C"},{"issue":"2","key":"10.1016\/j.cbpa.2016.05.006_bb0090","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.cbpa.2012.06.006","article-title":"Glutathione status and antioxidant enzymes in a crocodilian species from the swamps of the Brazilian Pantanal","volume":"163","author":"Hermes-Lima","year":"2012","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0095","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.freeradbiomed.2015.07.156","article-title":"Preparation for oxidative stress under hypoxia and metabolic depression: revisiting the proposal two decades later","volume":"89","author":"Hermes-Lima","year":"2015","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.chemosphere.2014.01.031","article-title":"Concentrations of trace elements in American alligators (Alligator mississippiensis) from Florida, USA","volume":"108","author":"Horai","year":"2014","journal-title":"Chemosphere"},{"issue":"10","key":"10.1016\/j.cbpa.2016.05.006_bb0105","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.3109\/00498258909043171","article-title":"The hepatic microsomal mixed-function oxygenase (MFO) system of Alligator mississippiensis: induction by 3-methylcholanthrene (MC)","volume":"19","author":"Jewell","year":"1989","journal-title":"Xenobiotica"},{"issue":"1\u20132","key":"10.1016\/j.cbpa.2016.05.006_bb0110","first-page":"30","article-title":"Chronic incidental lead ingestion in a group of captive-reared alligators (Alligator mississippiensis): possible contribution to reproductive failure","volume":"142","author":"Lance","year":"2006","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0115","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2307\/1540","article-title":"The length-weight relationship and seasonal cycle in gonad weight and condition in Perch (Perca fluviatilis)","volume":"20","author":"Le Cren","year":"1951","journal-title":"J. Anim. Ecol."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0120","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/jn\/125.6.1438","article-title":"Glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase are differentially regulated in rats by dietary selenium","volume":"125","author":"Lei","year":"1995","journal-title":"J. Nutr."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0125","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0076-6879(94)33040-9","article-title":"Carbonyl assays for determination of oxidatively modified proteins","volume":"233","author":"Levine","year":"1994","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0130","series-title":"Casarett & Doull's Toxicology: the Basic Science of Poisons","first-page":"931","article-title":"Toxicity of metals","author":"Liu","year":"2008"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0135","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0025-326X(01)00060-1","article-title":"Contaminant-stimulated reactive oxygen species productionand oxidative damage in aquatic organisms","volume":"42","author":"Livingstone","year":"2001","journal-title":"Mar. Pollut. Bull."},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0140","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.aquatox.2010.10.006","article-title":"Environmentally induced oxidative stress in aquatic animals","volume":"101","author":"Lushchak","year":"2011","journal-title":"Aquat. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.cbpa.2016.05.006_bb0150","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0048-9697(01)00995-0","article-title":"Catchment-specific element signatures in estuarine crocodiles (Crocodylus porosus) from the alligator rivers region, northern Australia","volume":"287","author":"Markich","year":"2002","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0155","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.cbpa.2007.09.016","article-title":"Febrile response to infection in the American alligator (Alligator mississippiensis)","volume":"148","author":"Merchant","year":"2007","journal-title":"Comp. Biochem. Physiol. A"},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0160","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.cbpb.2008.09.089","article-title":"Production of superoxide ions by leukocytes of the American alligator (Alligator mississippiensis)","volume":"152","author":"Merchant","year":"2009","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0165","doi-asserted-by":"crossref","first-page":"3170","DOI":"10.1016\/S0021-9258(19)45228-9","article-title":"The role of superoxide dismutase anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase","volume":"247","author":"Misra","year":"1972","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0170","series-title":"NORMA Oficial Mexicana Que establece los l\u00ed\u00admites m\u00e1ximos permisibles de contaminantes en las descargas de aguas residuales en aguas y bienes nacionales","author":"NOM-001-ECOL-1996","year":"1996"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0175","series-title":"NORMA Oficial Mexicana, Protecci\u00f3n ambiental-Especies nativas de M\u00e9xico de flora y fauna silvestres-Categor\u00edas de riesgo y especificaciones para su inclusi\u00f3n, exclusi\u00f3n o cambio-Lista de especies en riesgo","author":"NOM-059-SEMARNAT-2010","year":"2010"},{"issue":"6","key":"10.1016\/j.cbpa.2016.05.006_bb0180","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.envint.2009.02.006","article-title":"The toxicology of climate change: environmental contaminants in a warming world","volume":"35","author":"Noyes","year":"2009","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.cbpa.2016.05.006_bb0185","doi-asserted-by":"crossref","first-page":"511","DOI":"10.7589\/0090-3558-47.3.511","article-title":"Hematologic and plasma biochemical reference intervals for Morelet's crocodiles (Crocodylus moreletii) in the northern wetlands of Campeche, Mexico","volume":"47","author":"Padilla","year":"2011","journal-title":"J. Wildl. Dis."},{"issue":"2\u20134","key":"10.1016\/j.cbpa.2016.05.006_bb0190","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1159\/000213588","article-title":"Ageing in reptiles","volume":"40","author":"Patnaik","year":"1994","journal-title":"Gerontology"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0195","doi-asserted-by":"crossref","first-page":"22,028","DOI":"10.1016\/S0021-9258(18)54740-2","article-title":"Detection of catalase in rat heart mitochondria","volume":"266","author":"Radi","year":"1991","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0200","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.scitotenv.2006.11.010","article-title":"Metals and organochlorine pesticides in caudal scutes of crocodiles from Belize and Costa Rica","volume":"373","author":"Rainwater","year":"2007","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0205","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.envpol.2007.07.018","article-title":"Plasma vitellogenin in Morelet's crocodiles from contaminated habitats in northern Belize","volume":"153","author":"Rainwater","year":"2008","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0210","series-title":"Norma Oficial Mexicana NOM-062-ZOO-1999 Especificaciones t\u00e9cnicas para la producci\u00f3n, cuidado y el uso de animales de laboratorio","first-page":"1","author":"SAGARPA","year":"2001"},{"issue":"1","key":"10.1016\/j.cbpa.2016.05.006_bb0215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0304-3940(99)00269-4","article-title":"Hypoxia stimulates cerebral blood flow in the estuarine crocodile (Crocodylus porosus)","volume":"267","author":"S\u00f6derstr\u00f6m","year":"1999","journal-title":"Neurosci. Lett."},{"issue":"7","key":"10.1016\/j.cbpa.2016.05.006_bb0220","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.chemosphere.2004.12.074","article-title":"The role of soil organic carbon in the global cycling of persistent organic pollutants (POPs): interpreting and modelling field data","volume":"60","author":"Sweetman","year":"2005","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.cbpa.2016.05.006_bb0225","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00128-014-1349-8","article-title":"Metals in the caudal scutes of Morelet's crocodile (Crocodylus moreletii) from the southern Gulf of Mexico","volume":"93","author":"Trillanes","year":"2014","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpa.2016.05.006_bb0230","first-page":"141","article-title":"Multivariate analysis of ecotoxicological data using ordination: demonstration of utility on the basis of various examples","volume":"9","author":"van den Brink","year":"2003","journal-title":"Aust. J. Ecotoxicol."},{"issue":"2","key":"10.1016\/j.cbpa.2016.05.006_bb0235","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/02772240802075329","article-title":"Prooxidant and antioxidant sex-linked response and its relationship to mixed oxidase function enzymes in liver of Ameca splendens, an endangered goodeid fish exposed to PCBs","volume":"91","author":"Vega-L\u00f3pez","year":"2009","journal-title":"Toxicol. Environ. Chem."},{"issue":"4","key":"10.1016\/j.cbpa.2016.05.006_bb0240","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.cbpa.2013.01.026","article-title":"Relations of oxidative stress in freshwater phytoplankton with heavy metals and polycyclic aromatic hydrocarbons","volume":"165","author":"Vega-L\u00f3pez","year":"2013","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2016.05.006_bb0245","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0166-445X(91)90033-6","article-title":"Prooxidant and antioxidant mechanism in aquatic organisms","volume":"19","author":"Winston","year":"1991","journal-title":"Aquat. Toxicol."},{"issue":"8","key":"10.1016\/j.cbpa.2016.05.006_bb0250","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.1021\/acs.est.5b00071","article-title":"How does predation affect the bioaccumulation of hydrophobic organic compounds in aquatic organisms?","volume":"49","author":"Xia","year":"2015","journal-title":"Environ. Sci. Technol."}],"updated-by":[{"DOI":"10.1016\/j.cbpa.2017.02.025","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000}}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643316301052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643316301052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:10:51Z","timestamp":1761084651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643316301052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":49,"alternative-id":["S1095643316301052"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2016.05.006","relation":{},"ISSN":["1095-6433"],"issn-type":[{"value":"1095-6433","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Usefulness of oxidative stress biomarkers evaluated in the snout scraping, serum and Peripheral Blood Cells of Crocodylus moreletii from Southeast Campeche for assessment of the toxic impact of PAHs, metals and total phenols","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2016.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}