{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:40:40Z","timestamp":1789346440709,"version":"build-2803163510"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.cbpa.2020.110653","type":"journal-article","created":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T16:45:54Z","timestamp":1578501954000},"page":"110653","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Differential protein phosphorylation is responsible for hypoxia-induced regulation of the Akt\/mTOR pathway in naked mole rats"],"prefix":"10.1016","volume":"242","author":[{"given":"Rasha","family":"Al-attar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine L.","family":"Childers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vu C.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew E.","family":"Pamenter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth B.","family":"Storey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpa.2020.110653_bb0005","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.cryobiol.2019.01.006","article-title":"Metabolic reorganization in winter: regulation of pyruvate dehydrogenase (PDH) during long-term freezing and anoxia","volume":"86","author":"Al-Attar","year":"2019","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2020.110653_bb0010","doi-asserted-by":"crossref","first-page":"81","DOI":"10.5483\/BMBRep.2016.49.2.261","article-title":"The role of insulin\/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster","volume":"49","author":"Altintas","year":"2016","journal-title":"BMB Rep."},{"key":"10.1016\/j.cbpa.2020.110653_bb0015","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.2174\/092986712801661130","article-title":"Homeostasis and the importance for a balance between AKT\/mTOR activity and intracellular signaling","volume":"19","author":"Altomare","year":"2012","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0020","doi-asserted-by":"crossref","first-page":"17350","DOI":"10.1073\/pnas.1313473110","article-title":"Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage","volume":"110","author":"Azpurua","year":"2013","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cbpa.2020.110653_bb0025","doi-asserted-by":"crossref","first-page":"37400","DOI":"10.1074\/jbc.274.52.37400","article-title":"Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252","volume":"274","author":"Balendran","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0145587","article-title":"The insulin-like growth factor system in the long-lived naked mole-rat","volume":"10","author":"Brohus","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.cbpa.2020.110653_bb0035","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1128\/MCB.00310-08","article-title":"PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression","volume":"28","author":"Chang","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0040","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5732\/cjc.012.10263","article-title":"IGF-1R as an anti-cancer target-trials and tribulations","volume":"32","author":"Chen","year":"2013","journal-title":"Chin. J. Cancer"},{"key":"10.1016\/j.cbpa.2020.110653_bb0045","article-title":"Naked mole rats exhibit metabolic but not ventilatory plasticity following chronic sustained hypoxia","volume":"283","author":"Chung","year":"2016","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.cbpa.2020.110653_bb0050","doi-asserted-by":"crossref","first-page":"106","DOI":"10.3389\/fphys.2019.00106","article-title":"Glutamatergic receptors modulate normoxic but not hypoxic ventilation and metabolism in naked mole rats","volume":"10","author":"Dzal","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0055","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1113\/JP274556","article-title":"Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo","volume":"595","author":"Gan","year":"2017","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0060","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jbior.2017.06.003","article-title":"GSK3 and its interactions with the PI3K\/AKT\/mTOR signalling network","volume":"65","author":"Hermida","year":"2017","journal-title":"Adv. Biol. Regul."},{"key":"10.1016\/j.cbpa.2020.110653_bb0065","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/aje.12448","article-title":"The microenvironment of naked mole-rat burrows in East Africa","volume":"56","author":"Holtze","year":"2018","journal-title":"Afr. J. Ecol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0070","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nature01298","article-title":"IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice","volume":"421","author":"Holzenberger","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cbpa.2020.110653_bb0075","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.cbpb.2018.01.004","article-title":"Divergent behavioural responses to acute hypoxia between individuals and groups of naked mole rats","volume":"224","author":"Houlahan","year":"2018","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0080","doi-asserted-by":"crossref","first-page":"8688","DOI":"10.1074\/jbc.M110.141754","article-title":"Regulation of ribosomal protein S6 phosphorylation by casein kinase 1 and protein phosphatase 1","volume":"286","author":"Hutchinson","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0085","doi-asserted-by":"crossref","DOI":"10.1098\/rsbl.2017.0545","article-title":"Behavioural responses of naked mole rats to acute hypoxia and anoxia","volume":"13","author":"Ilacqua","year":"2017","journal-title":"Biol. Lett."},{"key":"10.1016\/j.cbpa.2020.110653_bb0090","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/ncb839","article-title":"TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling","volume":"4","author":"Inoki","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0095","first-page":"97","article-title":"The evolutionary history, population biology and social structure of African mole-rats: family Bathyergidae","volume":"335","author":"Jarvis","year":"1990","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.cbpa.2020.110653_bb0100","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.2217\/fon.13.49","article-title":"Control of oncogenesis by eIF2\u03b1 phosphorylation: implications in PTEN and PI3K\u2013Akt signaling and tumor treatment","volume":"9","author":"Koromilas","year":"2013","journal-title":"Future Oncol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0105","doi-asserted-by":"crossref","first-page":"41171","DOI":"10.1074\/jbc.M111.280982","article-title":"Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45\/p90 ribosomal S6 kinase (ORF45\/RSK) signaling axis facilitates protein translation during kaposi sarcoma-associated herpesvirus (KSHV) lytic replication","volume":"286","author":"Kuang","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0110","doi-asserted-by":"crossref","first-page":"23785","DOI":"10.1074\/jbc.M605269200","article-title":"Role of the activation loop tyrosines in regulation of the insulin-like growth factor I receptor-tyrosine kinase","volume":"281","author":"Li","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0115","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.cub.2005.02.053","article-title":"Rheb binds and regulates the mTOR kinase","volume":"15","author":"Long","year":"2005","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0120","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1006\/dbio.2000.9975","article-title":"Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth","volume":"229","author":"Lupu","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0125","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cbpb.2017.12.006","article-title":"Strategies of biochemical adaptation for hibernation in a south American marsupial, Dromiciops gliroides\u202f: 2. Control of the Akt pathway and protein translation machinery","volume":"224","author":"Luu","year":"2018","journal-title":"Comp. Biochem. Physiol. Part B Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0130","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cell.2017.04.001","article-title":"AKT\/PKB signaling: navigating the network","volume":"169","author":"Manning","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.cbpa.2020.110653_bb0135","doi-asserted-by":"crossref","first-page":"7505","DOI":"10.1128\/JVI.73.9.7505-7514.1999","article-title":"Translation initiation factor eIF4B interacts with a picornavirus internal ribosome entry site in both 48S and 80S initiation complexes independently of initiator AUG location","volume":"73","author":"Ochs","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0140","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1128\/jvi.76.5.2113-2122.2002","article-title":"Interaction of translation initiation factor eIF4B with the poliovirus internal ribosome entry site","volume":"76","author":"Ochs","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0145","article-title":"Do naked mole rats accumulate a metabolic acidosis or an oxygen debt in severe hypoxia?","volume":"222","author":"Pamenter","year":"2019","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0150","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1126\/science.aab3896","article-title":"Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat","volume":"356","author":"Park","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.cbpa.2020.110653_bb0155","doi-asserted-by":"crossref","first-page":"31","DOI":"10.32607\/20758251-2017-9-4-31-41","article-title":"Genome stability maintenance in naked mole-rat","volume":"9","author":"Petruseva","year":"2017","journal-title":"Acta Nat."},{"key":"10.1016\/j.cbpa.2020.110653_bb0160","doi-asserted-by":"crossref","first-page":"e1591","DOI":"10.1038\/cddis.2014.554","article-title":"Phosphorylation of the translation initiation factor eIF2\u03b1 at serine 51 determines the cell fate decisions of Akt in response to oxidative stress","volume":"6","author":"Rajesh","year":"2015","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cbpa.2020.110653_bb0165","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/emboj\/19.3.434","article-title":"Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI","volume":"19","author":"Raught","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.cbpa.2020.110653_bb0170","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1038\/sj.emboj.7600193","article-title":"Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases","volume":"23","author":"Raught","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.cbpa.2020.110653_bb0175","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.cryobiol.2006.08.001","article-title":"Stress-induced activation of the AMP-activated protein kinase in the freeze-tolerant frog Rana sylvatica","volume":"53","author":"Rider","year":"2006","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2020.110653_bb0180","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/jez.696","article-title":"Regulation of cell cycle components during exposure to anoxia or dehydration stress in the wood frog, Rana sylvatica","volume":"315A","author":"Roufayel","year":"2011","journal-title":"J. Exp. Zool. Part A Ecol. Genet. Physiol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0185","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0014-5793(89)81452-8","article-title":"Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation phosphorylated EF-2 is unable to catalyze translocation","volume":"251","author":"Ryazanov","year":"1989","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cbpa.2020.110653_bb0190","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41568-018-0004-9","article-title":"Mechanisms of cancer resistance in long-lived mammals","volume":"18","author":"Seluanov","year":"2018","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.cbpa.2020.110653_bb0195","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1038\/sj.emboj.7601166","article-title":"The mTOR\/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity","volume":"25","author":"Shahbazian","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.cbpa.2020.110653_bb0200","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1677\/joe.0.1670107","article-title":"Decreased Akt kinase activity and insulin resistance in C57BL\/KsJ-Leprdb\/db mice","volume":"167","author":"Shao","year":"2000","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0205","series-title":"The Biology of the Naked Mole-Rat","author":"Sherman","year":"1991"},{"key":"10.1016\/j.cbpa.2020.110653_bb0210","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ics.2004.08.072","article-title":"Molecular mechanisms of anoxia tolerance","volume":"1275","author":"Storey","year":"2004","journal-title":"Int. Congr. Ser."},{"key":"10.1016\/j.cbpa.2020.110653_bb0215","series-title":"Functional Metabolism","first-page":"415","article-title":"Oxygen limitation and metabolic rate depression","author":"Storey","year":"2005"},{"key":"10.1016\/j.cbpa.2020.110653_bb0220","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1152\/physrev.00016.2016","article-title":"Molecular physiology of freeze tolerance in vertebrates","volume":"97","author":"Storey","year":"2017","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbpa.2020.110653_bb0225","doi-asserted-by":"crossref","first-page":"12929","DOI":"10.1021\/bi0008682","article-title":"Phosphorylation of serine 51 in initiation factor 2\u03b1 (eIF2\u03b1) promotes complex formation between eIF2\u03b1(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B \u2020","volume":"39","author":"Sudhakar","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.cbpa.2020.110653_bb0230","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.gpb.2015.03.006","article-title":"Regulation of the PI3K\/AKT pathway and fuel utilization during primate torpor in the gray mouse lemur, Microcebus murinus","volume":"13","author":"Tessier","year":"2015","journal-title":"Genomics, Proteomics Bioinforma."},{"key":"10.1016\/j.cbpa.2020.110653_bb0235","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3389\/fonc.2013.00165","article-title":"The paradox of Akt-mTOR interactions","volume":"3","author":"Vadlakonda","year":"2013","journal-title":"Front. Oncol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0240","doi-asserted-by":"crossref","first-page":"48627","DOI":"10.1074\/jbc.C100556200","article-title":"Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex","volume":"276","author":"Vazquez","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0245","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1161\/CIRCRESAHA.118.312789","article-title":"Protein S -nitrosylation controls glycogen synthase kinase 3\u03b2 function independent of its phosphorylation state","volume":"122","author":"Wang","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.cbpa.2020.110653_bb0250","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1152\/physiol.00024.2006","article-title":"The mTOR pathway in the control of protein synthesis","volume":"21","author":"Wang","year":"2006","journal-title":"Physiology"},{"key":"10.1016\/j.cbpa.2020.110653_bb0255","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1242\/jeb.066225","article-title":"Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels","volume":"215","author":"Wu","year":"2012","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2020.110653_bb0260","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.4161\/cc.19799","article-title":"Pattern of cellular quiescence over the hibernation cycle in liver of thirteen-lined ground squirrels","volume":"11","author":"Wu","year":"2012","journal-title":"Cell Cycle"},{"key":"10.1016\/j.cbpa.2020.110653_bb0265","doi-asserted-by":"crossref","first-page":"109941","DOI":"10.18632\/oncotarget.22767","article-title":"HIF-1\u03b1 contributes to hypoxia adaptation of the naked mole rat","volume":"8","author":"Xiao","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.cbpa.2020.110653_bb0270","doi-asserted-by":"crossref","first-page":"7779","DOI":"10.1038\/sj.onc.1204984","article-title":"The protein kinase PKB\/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change","volume":"20","author":"Yamaguchi","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.cbpa.2020.110653_bb0275","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1158\/0008-5472.CAN-12-4277","article-title":"eIF4B phosphorylation by Pim kinases plays a critical role in cellular transformation by Abl oncogenes","volume":"73","author":"Yang","year":"2013","journal-title":"Cancer Res."},{"key":"10.1016\/j.cbpa.2020.110653_bb0280","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1242\/dev.137075","article-title":"Proliferation, survival and metabolism: the role of PI3K\/AKT\/mTOR signalling in pluripotency and cell fate determination","volume":"143","author":"Yu","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.cbpa.2020.110653_bb0285","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0021-9258(17)35272-9","article-title":"The regulatory role of known tyrosine autophosphorylation sites of the insulin receptor kinase domain. An assessment by replacement with neutral and negatively charged amino acids","volume":"266","author":"Zhang","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpa.2020.110653_bb0290","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.2436","article-title":"RBioplot: an easy-to-use R pipeline for automated statistical analysis and data visualization in molecular biology and biochemistry","volume":"4","author":"Zhang","year":"2016","journal-title":"PeerJ"}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643320300052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643320300052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:14:14Z","timestamp":1761084854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643320300052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":58,"alternative-id":["S1095643320300052"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2020.110653","relation":{},"ISSN":["1095-6433"],"issn-type":[{"value":"1095-6433","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential protein phosphorylation is responsible for hypoxia-induced regulation of the Akt\/mTOR pathway in naked mole rats","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2020.110653","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110653"}}