{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T21:08:13Z","timestamp":1761167293319,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.cbpa.2021.111122","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T11:49:46Z","timestamp":1637840986000},"page":"111122","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Melanin-concentrating hormone interferes with the hypothalamic-pituitary-gonad axis in the Mozambique tilapia"],"prefix":"10.1016","volume":"265","author":[{"given":"Jyoti","family":"Kumbar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.B.","family":"Ganesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpa.2021.111122_bb0005","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00441-002-0660-6","article-title":"Immunocytochemical localization and ontogenic development of melanin-concentrating hormone in the brain of a pleuronectiform fish, the barfin flounder","volume":"311","author":"Amano","year":"2003","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cbpa.2021.111122_bb0030","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1749-6632.1998.tb10760.x","article-title":"The melanin-concentrating hormone system in fish","volume":"839","author":"Balm","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"31","key":"10.1016\/j.cbpa.2021.111122_bb0035","doi-asserted-by":"crossref","first-page":"9379","DOI":"10.1021\/bi010867p","article-title":"Short segment of human melanin-concentrating hormone that is sufficient for full activation of human melanin-concentrating hormone receptors 1 and 2","volume":"40","author":"Bednarek","year":"2001","journal-title":"Biochemistry"},{"key":"10.1016\/j.cbpa.2021.111122_bb0040","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1515\/med-2018-0040","article-title":"The melanin-concentrating hormone system in human, rodent and avian brain","volume":"13","author":"Bencze","year":"2018","journal-title":"Open Med."},{"key":"10.1016\/j.cbpa.2021.111122_bb0045","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/jfb.14183","article-title":"Domperidone treatment attenuates stress-induced suppression of reproduction in viviparous mosquitofish Gambusia affinis","volume":"96","author":"Bhat","year":"2020","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0050","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1159\/000098334","article-title":"Regulation of the hypothalamic melanin-concentrating hormone neurons by sex steroids in the goldfish: possible role in the modulation of luteinizing hormone secretion","volume":"84","author":"Cerd\u00e1-Reverter","year":"2006","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.cbpa.2021.111122_bb0055","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1095\/biolreprod64.5.1466","article-title":"Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels","volume":"64","author":"Chiocchio","year":"2001","journal-title":"Biol. Reprod."},{"issue":"3\u20134","key":"10.1016\/j.cbpa.2021.111122_bb0060","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000091693","article-title":"Expression and differential effects of the activation of glucocorticoid receptors in mouse gonadotropin-releasing hormone neurons","volume":"82","author":"Dondi","year":"2005","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.cbpa.2021.111122_bb0065","first-page":"45","article-title":"Follicular development status and profile of 17\u03b2 estradiol and cortisol levels during the spawning cycle in Oreochromis mossambicus (Peters)","volume":"61","author":"Ganesh","year":"2014","journal-title":"Ind. J. Fish."},{"key":"10.1016\/j.cbpa.2021.111122_bb0070","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0196-9781(96)00337-3","article-title":"\u03b1-Melanocyte-stimulating hormone (\u03b1-MSH) and melanin-concentrating hormone (MCH) modify monoaminergic levels in the preoptic area of the rat","volume":"18","author":"Gonzalez","year":"1997","journal-title":"Peptides"},{"key":"10.1016\/j.cbpa.2021.111122_bb0075","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1677\/joe.0.1280261","article-title":"The influence of repeated stress on the release of melanin-concentrating hormone in the rainbow trout","volume":"128","author":"Green","year":"1991","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0080","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/jmor.20034","article-title":"Development of the follicle complex and oocyte staging in red drum, Sciaenops ocellatus Linnaeus, 1776 (Perciformes, Sciaenidae)","volume":"273","author":"Grier","year":"2012","journal-title":"J. Morphol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0085","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1677\/jme.0.0140199","article-title":"Expression of tilapia prepro-melanin-concentrating hormone mRNA in hypothalamic and neurohypophysial cells","volume":"14","author":"Gr\u00f6neveld","year":"1995","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0090","series-title":"Advances in Comparative Endocrinology","first-page":"1023","article-title":"The effects of a-MSH and MCH on the proliferation of rainbow trout (Oncorhynchus mykiss) lymphocytes in vitro","author":"Harris","year":"1997"},{"key":"10.1016\/j.cbpa.2021.111122_bb0095","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/305321a0","article-title":"Characterization of melanin-concentrating hormone in chum salmon pituitaries","volume":"305","author":"Kawauchi","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.cbpa.2021.111122_bb0100","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/BF00318885","article-title":"Development of melanin-concentrating hormone-immunoreactive elements in the brain of gilthead seabream (Sparus auratus)","volume":"282","author":"Mancera","year":"1995","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cbpa.2021.111122_bb0105","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.neulet.2006.02.005","article-title":"Central administration of melanin-concentrating hormone (MCH) suppresses food intake, but not locomotor activity, in the goldfish, Carassius auratus","volume":"399","author":"Matsuda","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cbpa.2021.111122_bb0110","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s00441-006-0347-5","article-title":"Feeding-induced changes of melanin-concentrating hormone (MCH)-like immunoreactivity in goldfish brain","volume":"328","author":"Matsuda","year":"2007","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cbpa.2021.111122_bb0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.cbpa.2008.10.002","article-title":"Relationship between melanin-concentrating hormone- and neuropeptide Y-containing neurons in the goldfish hypothalamus","volume":"153","author":"Matsuda","year":"2009","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.cbpa.2021.111122_bb0120","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/0196-9781(89)90112-5","article-title":"Melanin concentrating hormone (MCH): structure-function aspects of its melanocyte stimulating hormone-like (MSH-like) activity","volume":"10","author":"Matsunaga","year":"1989","journal-title":"Peptides"},{"key":"10.1016\/j.cbpa.2021.111122_bb0125","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1046\/j.1365-2826.2000.00440.x","article-title":"Melanin-concentrating hormone, melanocortin receptors and regulation of luteinising hormone release","volume":"12","author":"Murray","year":"2000","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0130","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1365-2826.2005.01397.x","article-title":"Evidence for a stimulatory action of melanin-concentrating hormone on luteinising hormone release involving MCH1 and Melanocortin-5 receptors","volume":"18","author":"Murray","year":"2006","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0135","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3389\/fendo.2020.00586","article-title":"Morphological evidence for functional crosstalk between multiple GnRH systems in the male tilapia, Oreochromis niloticus","volume":"11","author":"Ogawa","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0140","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00441-002-0654-4","article-title":"Melanin-concentrating hormone system in the brain and skin of the cichlid fish Cichlasoma dimerus: anatomical localization, ontogeny and distribution in comparison to alpha-melanocyte-stimulating hormone-expressing cells","volume":"311","author":"Pandolfi","year":"2003","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cbpa.2021.111122_bb0145","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1095\/biolreprod64.5.1466","article-title":"Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels","volume":"64","author":"Sara","year":"2001","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbpa.2021.111122_bb0150","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/fendo.2014.00036","article-title":"Central pathways integrating metabolism and reproduction in teleosts","volume":"5","author":"Shahjahan","year":"2014","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"2","key":"10.1016\/j.cbpa.2021.111122_bb0155","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.bbr.2008.08.026","article-title":"The effects of stressful stimuli and hypothalamic-pituitary-adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents","volume":"197","author":"Smith","year":"2009","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.cbpa.2021.111122_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1507\/endocrj.51.1","article-title":"Translational medicine in fish-derived peptides: from fish endocrinology to human physiology and diseases","volume":"51","author":"Takahashi","year":"2004","journal-title":"Endocr. J."},{"issue":"1","key":"10.1016\/j.cbpa.2021.111122_bb0165","first-page":"369","article-title":"Expression of melanin-concentrating hormone receptor messenger ribonucleic acid in tumor tissues of pheochromocytoma, ganglioneuroblastoma, and neuroblastoma","volume":"86","author":"Takahashi","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.cbpa.2021.111122_bb0170","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1095\/biolreprod60.3.642","article-title":"Glucocorticoid receptor immunoreactivity in neurons and pituitary cells implicated in reproductive functions in rainbow trout: a double immunohistochemical study","volume":"60","author":"Teitsma","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cbpa.2021.111122_bb0175","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1046\/j.1365-2826.2000.00482.x","article-title":"Intracerebroventricular administration of melanin-concentrating hormone suppresses pulsatile luteinizing hormone release in the female rat","volume":"12","author":"Tsukamura","year":"2000","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0180","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.mce.2011.09.015","article-title":"A preliminary investigation of the role of melanin-concentrating hormone (MCH) and its receptors in appetite regulation of winter flounder (Pseudopleuronectes americanus)","volume":"348","author":"Tuziak","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.cbpa.2021.111122_bb0185","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.peptides.2013.10.005","article-title":"Melanin-concentrating hormone (MCH) and gonadotropin-releasing hormones (GnRH) in Atlantic cod, Gadus morhua: tissue distributions, early ontogeny and effects of fasting","volume":"50","author":"Tuziak","year":"2013","journal-title":"Peptides"},{"key":"10.1016\/j.cbpa.2021.111122_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2019.101999","article-title":"Leucine-enkephalin-immunoreactive neurons in the brain of the cichlid fish Oreochromis mossambicus","volume":"81","author":"Vijayalaxmi","year":"2020","journal-title":"Neuropeptides"},{"key":"10.1016\/j.cbpa.2021.111122_bb0195","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.brainres.2004.11.066","article-title":"Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons","volume":"1041","author":"Williamson-Hughes","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.cbpa.2021.111122_bb0200","doi-asserted-by":"crossref","first-page":"17217","DOI":"10.1073\/pnas.0908200106","article-title":"Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction","volume":"106","author":"Wu","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cbpa.2021.111122_bb0205","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s10695-018-0586-x","article-title":"Characterization and expression of melanin-concentrating hormone (MCH) in common carp (Cyprinus carpio) during fasting and reproductive cycle","volume":"45","author":"Xu","year":"2019","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpa.2021.111122_bb0210","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0168-0102(98)00022-4","article-title":"Preoptic gonadotropin-releasing hormone (GnRH) neurons innervate the pituitary in teleosts","volume":"31","author":"Yamamoto","year":"1998","journal-title":"Neurosci. Res."}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular &amp; Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643321002300?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643321002300?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:18:06Z","timestamp":1761085086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643321002300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":38,"alternative-id":["S1095643321002300"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2021.111122","relation":{},"ISSN":["1095-6433"],"issn-type":[{"type":"print","value":"1095-6433"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melanin-concentrating hormone interferes with the hypothalamic-pituitary-gonad axis in the Mozambique tilapia","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2021.111122","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111122"}}