{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T15:14:32Z","timestamp":1783782872418,"version":"3.55.0"},"reference-count":180,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["122012100156\\u20135"],"award-info":[{"award-number":["122012100156\\u20135"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.cbpa.2026.112015","type":"journal-article","created":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T14:28:19Z","timestamp":1778423299000},"page":"112015","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Adaptations of the cardiovascular system in hibernating mammals."],"prefix":"10.1016","volume":"317","author":[{"given":"Vladislav S.","family":"Kuzmin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina K.","family":"Gaynullina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia A.","family":"Shvetsova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana S.","family":"Filatova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena S.","family":"Abramochkina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis V.","family":"Abramochkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1021\/acs.jproteome.3c00540","article-title":"Proteomic identification of seasonally expressed proteins contributing to heart function and the avoidance of skeletal muscle disuse atrophy in a hibernating mammal","volume":"23","author":"Abid","year":"2024","journal-title":"J. Proteome Res."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0010","first-page":"50","article-title":"Peculiarities of regulation of cardiac function in some mammals","volume":"46","author":"Abramochkin","year":"2006","journal-title":"Kardiologiia"},{"key":"10.1016\/j.cbpa.2026.112015_bb0015","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1134\/S0012496606020025","article-title":"Effect of acetylcholine on the action potential in the bat atrium and ventricle","volume":"407","author":"Abramochkin","year":"2006","journal-title":"Dokl. Biol. Sci."},{"key":"10.1016\/j.cbpa.2026.112015_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2022.111204","article-title":"Ionic currents underlying different patterns of electrical activity in working cardiac myocytes of mammals and non-mammalian vertebrates","volume":"268","author":"Abramochkin","year":"2022","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0025","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0006-8993(00)03285-6","article-title":"The effects of cooling and rewarming on the neuronal activity of pyramidal neurons in guinea pig hippocampal slices","volume":"893","author":"Aihara","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.cbpa.2026.112015_bib887","series-title":"QT Interval After Bariatric Surgery","author":"Al-Salameh","year":"2017"},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0030","first-page":"365","article-title":"Potential-dependent Ca2+ currents in isolated heart cells of hibernators","volume":"33","author":"Alekseev","year":"1994","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1016\/j.cbpa.2026.112015_bb0035","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/bies.20560","article-title":"Advances in molecular biology of hibernation in mammals","volume":"29","author":"Andrews","year":"2007","journal-title":"BioEssays"},{"key":"10.1016\/j.cbpa.2026.112015_bb0040","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1134\/S1067413615010026","article-title":"Hibernation of three species of the sciuridae family in Yakutia with a body temperature below zero","volume":"46","author":"Anufriev","year":"2015","journal-title":"Russ. J. Ecol."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018641","article-title":"Diet-independent remodeling of cellular membranes precedes seasonally changing body temperature in a hibernator","volume":"6","author":"Arnold","year":"2011","journal-title":"PloS One"},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0050","first-page":"910","article-title":"Effect of isoproterenol on contractility of the heart papillary muscles of a ground squirrel","volume":"55","author":"Averin","year":"2010","journal-title":"Biofizika"},{"key":"10.1016\/j.cbpa.2026.112015_bb0055","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1007\/s00360-021-01394-6","article-title":"\u03b11-adrenergic receptor regulates papillary muscle and aortic segment contractile function via modulation of store-operated Ca2+ entry in long-tailed ground squirrels Urocitellus undulatus","volume":"191","author":"Averin","year":"2021","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.cbpa.2026.112015_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2024.103785","article-title":"The effects of nickel chloride on papillary muscle contractility under normothermic and hypothermic conditions: comparison of active and hibernating ground squirrels (Urocitellus undulatus) with Wistar rats","volume":"119","author":"Averin","year":"2024","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0065","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cbpa.2016.12.017","article-title":"Effects of seasonal acclimatization on action potentials and sarcolemmal K+ currents in roach (Rutilus rutilus) cardiac myocytes","volume":"205","author":"Badr","year":"2017","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0070","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00360-017-1126-1","article-title":"Effects of seasonal acclimatization on thermal tolerance of inward currents in roach (Rutilus rutilus) cardiac myocytes","volume":"188","author":"Badr","year":"2018","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.cbpa.2026.112015_bb0075","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1126\/science.2740905","article-title":"Freeze avoidance in a mammal: body temperatures below 0\u00b0C in an Arctic hibernator","volume":"244","author":"Barnes","year":"1989","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/657589","article-title":"Increased cardiac alpha-myosin heavy chain in left atria and decreased myocardial insulin-like growth factor (Igf-I) expression accompany low heart rate in hibernating grizzly bears","volume":"84","author":"Barrows","year":"2011","journal-title":"Physiol. Biochem. Zool."},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0085","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.jshs.2020.11.009","article-title":"IGF1-PI3K-induced physiological cardiac hypertrophy: implications for new heart failure therapies, biomarkers, and predicting cardiotoxicity","volume":"10","author":"Bass-Stringer","year":"2021","journal-title":"J. Sport Health Sci."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0090","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/0011-2240(91)90042-M","article-title":"Seasonal variations in the rate and capacity of cardiac SR calcium accumulation in a hibernating species","volume":"28","author":"Belke","year":"1991","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2026.112015_bb0095","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2981\/wlb.1998.006","article-title":"Body temperature changes in wild-living badgers Meles meles through the winter","volume":"4","author":"Bevanger","year":"1998","journal-title":"Wild l. Biol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0100","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0248-4900(90)90367-C","article-title":"An efficient isolation procedure of ca-tolerant ventricular myocytes from ferret heart for applications in electrophysiological studies","volume":"70","author":"Bouron","year":"1990","journal-title":"Biol. Cell"},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0105","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1152\/physiolgenomics.00076.2005","article-title":"Digital transcriptome analysis indicates adaptive mechanisms in the heart of a hibernating mammal","volume":"23","author":"Brauch","year":"2005","journal-title":"Physiol. Genomics"},{"issue":"1\u20132","key":"10.1016\/j.cbpa.2026.112015_bb0110","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF00374970","article-title":"Temperature dependence of gap junction properties in neonatal rat heart cells","volume":"423","author":"Bukauskas","year":"1993","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpa.2026.112015_bb0115","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1152\/ajplegacy.1962.203.2.266","article-title":"Estimated regional blood flow by rubidium 86 distribution during arousal from hibernation","volume":"203","author":"Bullard","year":"1962","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0120","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1540-8159.2006.00336.x","article-title":"Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation","volume":"29","author":"Burashnikov","year":"2006","journal-title":"Pacing Clin. Electrophysiol."},{"issue":"9","key":"10.1016\/j.cbpa.2026.112015_bb0125","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/0024-3205(68)90046-5","article-title":"Effect of temperature on contractility of isolated atria from a hibernator and a non-hibernator","volume":"7","author":"Burlington","year":"1968","journal-title":"Life Sci."},{"issue":"2Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0130","first-page":"R357","article-title":"Coronary autoregulation and metabolism in hypothermic rat and ground squirrel hearts","volume":"256","author":"Burlington","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0135","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.resuscitation.2017.07.003","article-title":"The impact of hypothermia on serum potassium concentration: a systematic review","volume":"118","author":"Buse","year":"2017","journal-title":"Resuscitation"},{"issue":"4Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0140","first-page":"R722","article-title":"Isovolumetric performance of isolated ground squirrel and rat hearts at low temperature","volume":"247","author":"Caprette","year":"1984","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0145","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.7587","article-title":"The heart of a hibernator: EGFR and MAPK signaling in cardiac muscle during the hibernation of thirteen-lined ground squirrels, Ictidomys tridecemlineatus","volume":"7","author":"Childers","year":"2019","journal-title":"PeerJ"},{"issue":"9","key":"10.1016\/j.cbpa.2026.112015_bb0150","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1111\/j.1582-4934.2011.01497.x","article-title":"Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1\u03b1-mediated TRPC signalling","volume":"16","author":"Chu","year":"2012","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.cbpa.2026.112015_bb0155","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2170\/physiolsci.RP005906","article-title":"Effects of acute and chronic cooling on cardiorespiratory depression in rodents","volume":"57","author":"Deveci","year":"2007","journal-title":"J. Physiol. Sci."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bib886","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/cvr\/cvy305","article-title":"Hypothermia and cardiac electrophysiology: a systematic review of clinical and experimental data","volume":"115","author":"Dietrichs","year":"2019","journal-title":"Cardiovasc. Res."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0160","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1172\/JCI24178","article-title":"Protein kinase cascades in the regulation of cardiac hypertrophy","volume":"115","author":"Dorn","year":"2005","journal-title":"J. Clin. Invest."},{"issue":"5Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0165","first-page":"H1083","article-title":"Monophasic action potentials during induced hypothermia in hedgehog and guinea pig hearts","volume":"253","author":"Duker","year":"1987","journal-title":"Am. J. Physiol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0170","doi-asserted-by":"crossref","first-page":"H1035","DOI":"10.1152\/ajpheart.00786.2011","article-title":"Hypothermia-induced spatially discordant action potential duration alternans and arrhythmogenesis in nonhibernating versus hibernating mammals","volume":"303","author":"Egorov","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"11","key":"10.1016\/j.cbpa.2026.112015_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166143","article-title":"Hyperthermia influences the effects of Sodium Channel blocking drugs in human-induced pluripotent stem cell-derived cardiomyocytes","volume":"11","author":"El-Battrawy","year":"2016","journal-title":"PloS One"},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0180","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1085\/jgp.79.6.1115","article-title":"Kinetics of the sodium pump in red cells of different temperature sensitivity","volume":"79","author":"Ellory","year":"1982","journal-title":"J. Gen. Physiol."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0185","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1042\/bst0110330","article-title":"Adaptive changes in membrane-transport systems of hibernators","volume":"11","author":"Ellory","year":"1983","journal-title":"Biochem. Soc. Trans."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0190","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1006\/cryo.2000.2254","article-title":"Gene up-regulation in heart during mammalian hibernation","volume":"40","author":"Fahlman","year":"2000","journal-title":"Cryobiology"},{"issue":"9","key":"10.1016\/j.cbpa.2026.112015_bb0195","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.hrthm.2005.06.012","article-title":"Hibernator Citellus undulatus maintains safe cardiac conduction and is protected against tachyarrhythmias during extreme hypothermia: possible role of Cx43 and Cx45 up-regulation","volume":"2","author":"Fedorov","year":"2005","journal-title":"Heart Rhythm"},{"issue":"11","key":"10.1016\/j.cbpa.2026.112015_bb0200","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.hrthm.2008.08.030","article-title":"Electrophysiological mechanisms of antiarrhythmic protection during hypothermia in winter hibernating versus nonhibernating mammals","volume":"5","author":"Fedorov","year":"2008","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cbpa.2026.112015_bb0205","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1134\/S0022093023030298","article-title":"Effect of hibernation on electrical activity and potassium currents in the myocardium of long-tailed ground squirrel","volume":"59","author":"Filatova","year":"2023","journal-title":"J. Evol. Biochem. Phys."},{"key":"10.1016\/j.cbpa.2026.112015_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2023.111452","article-title":"Sodium current preserves electrical excitability in the heart of hibernating ground squirrel (Citellus undulatus)","volume":"282","author":"Filatova","year":"2023","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0215","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0033-0620(77)90015-9","article-title":"Cardiac muscle: excitability and passive electrical properties","volume":"19","author":"Fozzard","year":"1977","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.cbpa.2026.112015_bb0220","article-title":"Hibernation enhances contractile responses of basilar artery in ground squirrels: the role of rho-kinase and NO","volume":"301","author":"Gaynullina","year":"2025","journal-title":"Comp. Biochem. Physiol. Part A Mol. Integr. Physiol."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0225","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0300-9629(89)90046-7","article-title":"The effect of temperature on isolated perfused hearts of heterothermic marsupials","volume":"93","author":"Geiser","year":"1989","journal-title":"Comp. Biochem. Physiol. A Comp. Physiol."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0063111","article-title":"Membrane phospholipid fatty acid composition regulates cardiac SERCA activity in a hibernator, the Syrian hamster (Mesocricetus auratus)","volume":"8","author":"Giroud","year":"2013","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0235","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF00584839","article-title":"On the temperature dependence of the Na pump in sheep Purkinje fibres","volume":"402","author":"Glitsch","year":"1984","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpa.2026.112015_bb0240","doi-asserted-by":"crossref","first-page":"25329","DOI":"10.1073\/pnas.1914273116","article-title":"Extreme bradycardia and tachycardia in the world\u2019s largest animal","volume":"116","author":"Goldbogen","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0245","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.jmb.2011.03.015","article-title":"Lipid-mediated folding\/unfolding of phospholamban as a regulatory mechanism for the sarcoplasmic reticulum Ca2+-ATPase","volume":"408","author":"Gustavsson","year":"2011","journal-title":"J. Mol. Biol."},{"issue":"47","key":"10.1016\/j.cbpa.2026.112015_bb0250","doi-asserted-by":"crossref","first-page":"10367","DOI":"10.1021\/bi200759y","article-title":"Activating and deactivating roles of lipid bilayers on the ca(2+)-ATPase\/phospholamban complex","volume":"50","author":"Gustavsson","year":"2011","journal-title":"Biochemistry"},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0255","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF00230179","article-title":"Contractile and calcium regulating capacities of myocardia of different sized mammals scale with resting heart rate","volume":"106","author":"Hamilton","year":"1991","journal-title":"Mol. Cell. Biochem."},{"issue":"10","key":"10.1016\/j.cbpa.2026.112015_bb0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027021","article-title":"Deep sequencing the transcriptome reveals seasonal adaptive mechanisms in a hibernating mammal","volume":"6","author":"Hampton","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.cbpa.2026.112015_bb0265","article-title":"The protective effects on ischemia\u2013reperfusion injury mechanisms of the thoracic aorta in Daurian ground squirrels (Spermophilus dauricus) over the torpor\u2013arousal cycle of hibernation","volume":"23","author":"Han","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"23","key":"10.1016\/j.cbpa.2026.112015_bb0270","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252312888","article-title":"Involvement of melatonin, oxidative stress, and inflammation in the protective mechanism of the carotid artery over the torpor-arousal cycle of ground squirrels","volume":"25","author":"Hao","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"Pt4","key":"10.1016\/j.cbpa.2026.112015_bb0275","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1242\/jeb.198.4.931","article-title":"Parasympathetic influence on heart rate in euthermic and hibernating ground squirrels","volume":"198","author":"Harris","year":"1995","journal-title":"J. Exp. Biol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0280","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.241067","article-title":"Effects of Na+ channel isoforms and cellular environment on temperature tolerance of cardiac Na+ current in zebrafish (Danio rerio) and rainbow trout (Oncorhynchus mykiss)","volume":"224","author":"Haverinen","year":"2021","journal-title":"J. Exp. Biol."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0285","doi-asserted-by":"crossref","first-page":"R368","DOI":"10.1152\/ajpregu.00365.2014","article-title":"Myocardial performance and adaptive energy pathways in a torpid mammalian hibernator","volume":"309","author":"Heinis","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0290","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1016\/S0024-3205(02)01505-9","article-title":"Normalization of aortic function during arousal episodes in the hibernating ground squirrel","volume":"70","author":"Henning","year":"2002","journal-title":"Life Sci."},{"issue":"1Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0295","first-page":"R177","article-title":"Temperature dependence of electrophysiological properties of guinea pig and ground squirrel myocytes","volume":"263","author":"Herve","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0300","series-title":"The Electrophysiology of the Heart","author":"Hoffman","year":"1960"},{"issue":"7","key":"10.1016\/j.cbpa.2026.112015_bb0305","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1152\/ajpregu.00450.2012","article-title":"Temporal relationships of blood pressure, heart rate, baroreflex function, and body temperature change over a hibernation bout in Syrian hamsters","volume":"305","author":"Horwitz","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"Pt 3","key":"10.1016\/j.cbpa.2026.112015_bb0310","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1469-7793.2000.00795.x","article-title":"Functional coupling between glycolysis and excitation-contraction coupling underlies alternans in cat heart cells","volume":"524","author":"H\u00fcser","year":"2000","journal-title":"J. Physiol."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0315","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1161\/01.CIR.87.5.1715","article-title":"Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes","volume":"87","author":"Ito","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.cbpa.2026.112015_bb0320","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0306-4565(00)00012-7","article-title":"Physiological blocking of the mechanisms of cold death: theoretical and experimental considerations","volume":"25","author":"Ivanov","year":"2000","journal-title":"J. Therm. Biol."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0325","first-page":"826","article-title":"The hibernator heart--nature's model of resistance to ventricular fibrillation","volume":"31","author":"Johansson","year":"1996","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cbpa.2026.112015_bb0330","first-page":"12","article-title":"Low cardiac output as physiological phenomenon in hibernating, free-ranging Scandinavian brown bears (Ursus arctos) - an observational study","volume":"16","author":"J\u00f8rgensen","year":"2014","journal-title":"Cardiovasc. Ultrasound"},{"key":"10.1016\/j.cbpa.2026.112015_bb0335","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s42826-021-00102-3","article-title":"A comparative review on heart ion channels, action potentials and electrocardiogram in rodents and human: extrapolation of experimental insights to clinic","volume":"37","author":"Joukar","year":"2021","journal-title":"Lab. Anim. Res."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0340","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/j.1469-7793.1998.927bd.x","article-title":"Enhanced vasoconstrictor responses in renal and femoral arteries of the golden hamster during hibernation","volume":"512","author":"Karoon","year":"1998","journal-title":"J. Physiol."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0345","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1365-201X.1968.tb10877.x","article-title":"Temperature effects on the viscosity of blood and the aorta distension from a hibernator, Erinaceus europaeus L.","volume":"73","author":"Kirkeb\u00f6","year":"1968","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.cbpa.2026.112015_bb0350","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1113\/jphysiol.1993.sp019761","article-title":"Ionic mechanisms of action potential prolongation at low temperature in guinea-pig ventricular myocytes","volume":"468","author":"Kiyosue","year":"1993","journal-title":"J. Physiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0355","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s004240100683","article-title":"Rate-dependent changes in action potential duration and membrane currents in hamster ventricular myocytes","volume":"443","author":"Kocic","year":"2002","journal-title":"Pflugers Arch."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0360","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1161\/01.RES.59.2.221","article-title":"Excitation-contraction coupling in myocardium of nonhibernating and hibernating chipmunks: effects of isoprenaline, a high calcium medium, and ryanodine","volume":"59","author":"Kondo","year":"1986","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0365","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1476-5381.1987.tb10286.x","article-title":"Electrophysiological effects of ca antagonists, tetrodotoxin, [ca]o and [Na]o on myocardium of hibernating chipmunks: possible involvement of Na-ca exchange mechanism","volume":"91","author":"Kondo","year":"1987","journal-title":"Br. J. Pharmacol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0370","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/BF01951645","article-title":"Identification of a pre-hibernating state in myocardium from nonhibernating chipmunks","volume":"43","author":"Kondo","year":"1987","journal-title":"Experientia"},{"issue":"4662","key":"10.1016\/j.cbpa.2026.112015_bb0375","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1126\/science.6740332","article-title":"Calcium source for excitation-contraction coupling in myocardium of nonhibernating and hibernating chipmunks","volume":"225","author":"Kondo","year":"1984","journal-title":"Science"},{"issue":"4662","key":"10.1016\/j.cbpa.2026.112015_bib888","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1126\/science.6740332","article-title":"Calcium source for excitation-contraction coupling in myocardium of nonhibernating and hibernating chipmunks","volume":"225","author":"Kondo","year":"1984","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0380","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0022-2828(03)00174-3","article-title":"Nitric oxide-dependent vasodilation maintains blood flow in true hibernating myocardium","volume":"35","author":"Kudej","year":"2003","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0385","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1134\/S0012496619030050","article-title":"Hypothermia-induced postrepolarization refractoriness is the rReason of the atrial myocardium tolerance to the bioelectrical activity disorders in the hibernating and active ground squirrel Citellus undulatus","volume":"486","author":"Kuzmin","year":"2019","journal-title":"Dokl. Biol. Sci."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0390","first-page":"39","article-title":"Reversible inhibitory action of adenosine diphosphate ribose on isolated rat heart and rat heart in vivo","volume":"46","author":"Kuz'min","year":"2006","journal-title":"Kardiologiia"},{"issue":"11","key":"10.1016\/j.cbpa.2026.112015_bb0395","first-page":"53","article-title":"Influence of ADP-ribose, AMP and adenosine on bioelectric activity of hibernating ground squirrel atrium and papillary muscle","volume":"48","author":"Kuz'min","year":"2008","journal-title":"Kardiologiia"},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0400","first-page":"46","article-title":"The influence of purine nucleotides and adenosine on bioelectrical activity of bat (Pipistrellus nathusii) heart","volume":"48","author":"Kuz'min","year":"2008","journal-title":"Kardiologiia"},{"issue":"12","key":"10.1016\/j.cbpa.2026.112015_bb0405","first-page":"1399","article-title":"Hypothermia induced alteration of refractoriness in the ventricular myocardium of ground souirrel Citellus undulatus","volume":"100","author":"Kuz\u2019min","year":"2014","journal-title":"Ross. Fiziol. Zh. Im. I M Sechenova"},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0410","first-page":"311","article-title":"Effects of acute cooling\/rewarming on membrane potential and K(+) currents in rat ventricular myocytes","volume":"60","author":"Li","year":"2008","journal-title":"Sheng Li Xue Bao"},{"issue":"9","key":"10.1016\/j.cbpa.2026.112015_bb0415","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024787","article-title":"Ca2+ cycling in heart cells from ground squirrels: adaptive strategies for intracellular Ca2+ homeostasis","volume":"6","author":"Li","year":"2011","journal-title":"PloS One"},{"issue":"9","key":"10.1016\/j.cbpa.2026.112015_bb0420","doi-asserted-by":"crossref","first-page":"4221","DOI":"10.1021\/pr400580f","article-title":"Proteomic mechanisms of cardioprotection during mammalian hibernation in woodchucks, Marmota monax","volume":"12","author":"Li","year":"2013","journal-title":"J. Proteome Res."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0425","first-page":"127","article-title":"The cardiotropic activity of the nucleotides found in the composition of the low-molecular peptide subfraction obtained from the brain of hibernating susliks Citellus undulatus","volume":"35","author":"Liashkov","year":"1999","journal-title":"Zh. Evol. Biokhim. Fiziol."},{"issue":"17","key":"10.1016\/j.cbpa.2026.112015_bb0430","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.70531","article-title":"Seasonal variations in ventricular repolarization and tachyarrhythmias in hibernating brown bears (Ursus arctos arctos)","volume":"13","author":"Lindberg","year":"2025","journal-title":"Physiol. Rep."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0435","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0011-2240(91)90011-C","article-title":"Temperature effects on the Na and ca currents in rat and hedgehog ventricular muscle","volume":"28","author":"Liu","year":"1991","journal-title":"Cryobiology"},{"issue":"1Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0440","first-page":"R104","article-title":"Effects of temperature and pH on cardiac myofilament Ca2+ sensitivity in rat and ground squirrel","volume":"264","author":"Liu","year":"1993","journal-title":"Am. J. Physiol."},{"issue":"4Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0445","first-page":"R1121","article-title":"Ca2+ uptake by cardiac sarcoplasmic reticulum at low temperature in rat and ground squirrel","volume":"272","author":"Liu","year":"1997","journal-title":"Am. J. Physiol."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0450","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117747","article-title":"The regulation of troponins I, C and ANP by GATA4 and Nkx2-5 in heart of hibernating thirteen-lined ground squirrels, Ictidomys tridecemlineatus","volume":"10","author":"Luu","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0455","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0163-7258(84)90005-6","article-title":"Pharmacological aspects of mammalian hibernation","volume":"25","author":"Lyman","year":"1984","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.cbpa.2026.112015_bb0460","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/jcp.1030540107","article-title":"The effect of temperature on the isolated hearts of closely related hibernators and nonhibernators","volume":"54","author":"Lyman","year":"1959","journal-title":"J. Cell. Comp. Physiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0465","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1113\/jphysiol.1963.sp007204","article-title":"Autonomic control of circulation during the hibernating cycle in ground squirrels","volume":"168","author":"Lyman","year":"1963","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0470","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1098976","article-title":"Adenosine and P1 receptors: key targets in the regulation of sleep, torpor, and hibernation","volume":"14","author":"Ma","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0475","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cellsig.2018.07.004","article-title":"Agmatine modulates calcium handling in cardiomyocytes of hibernating ground squirrels through calcium-sensing receptor signaling","volume":"51","author":"Maltsev","year":"2018","journal-title":"Cell. Signal."},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0480","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1023\/A:1015540909212","article-title":"Ca-ATPase activity and protein composition of sarcoplasmic reticulum membranes isolated from skeletal muscles of typical hibernator, the ground squirrel Spermophilus undulatus","volume":"21","author":"Malysheva","year":"2001","journal-title":"Biosci. Rep."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0485","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1023\/A:1011917122289","article-title":"Characteristics of sarcoplasmic reticulum membrane preparations isolated from skeletal muscles of active and hibernating ground squirrel Spermophilus undulatus","volume":"66","author":"Malysheva","year":"2001","journal-title":"Biochemistry (Mosc.)"},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0490","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1007\/BF00261296","article-title":"Elevating intracellular free Mg2+ preserves sensitivity of Na(+)-K+ pump to ATP at reduced temperatures in guinea pig red blood cells","volume":"165","author":"Marjanovic","year":"1995","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.cbpa.2026.112015_bb0495","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1161\/01.RES.5.6.664","article-title":"Effects of low temperatures on transmembrane potentials of single fibers of the rabbit atrium","volume":"5","author":"Marshall","year":"1957","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0500","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pharmthera.2013.10.007","article-title":"Small and large animal models in cardiac contraction research: advantages and disadvantages","volume":"141","author":"Milani-Nejad","year":"2014","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0505","doi-asserted-by":"crossref","first-page":"R77","DOI":"10.1152\/ajpregu.1986.250.1.R77","article-title":"Vascular smooth muscle responsiveness in a hibernator: effects of season and temperature","volume":"250","author":"Miller","year":"1986","journal-title":"Am. J. Physiol. - Regul. Integr. Comp. Physiol."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0510","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S1095-6433(99)00130-0","article-title":"Regulation of cardiac rhythm in hibernating mammals","volume":"124","author":"Milsom","year":"1999","journal-title":"Comp. Biochem. Physiol. - A Mol. Integr. Physiol."},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0515","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1469-445X.2001.tb00046.x","article-title":"Vagal control of cardiorespiratory function in hibernation","volume":"86","author":"Milsom","year":"2001","journal-title":"Exp. Physiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0520","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.cardiores.2004.01.021","article-title":"Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs","volume":"63","author":"Molkentin","year":"2004","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0525","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/01.RES.0000231290.45676.d4","article-title":"Myostatin regulates cardiomyocyte growth through modulation of Akt signaling","volume":"99","author":"Morissette","year":"2006","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0530","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0022-5223(19)43326-6","article-title":"Mechanisms of ventricular fibrillation during hypothermia. Relative changes in myocardial refractory period and conduction velocity","volume":"51","author":"Mouritzen","year":"1966","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.cbpa.2026.112015_bb0540","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1134\/S0012496613040121","article-title":"The effect of agmatine on the rhythmoinotropic properties of the cardiac papillary muscle of hibernating animals","volume":"451","author":"Nakipova","year":"2013","journal-title":"Dokl. Biol. Sci."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bib889","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cryobiol.2007.07.001","article-title":"The seasonal peculiarities of force-frequency relationships in active ground squirrel Spermophilus undulatus ventricle","volume":"55","author":"Nakipova","year":"2007","journal-title":"Cryobiology"},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0545","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3390\/ph14080748","article-title":"Canine myocytes represent a good model for human ventricular cells regarding their electrophysiological properties","volume":"14","author":"N\u00e1n\u00e1si","year":"2021","journal-title":"Pharmaceuticals (Basel)"},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0550","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00360-009-0421-x","article-title":"Cardiac function adaptations in hibernating grizzly bears (Ursus arctos horribilis)","volume":"180","author":"Nelson","year":"2010","journal-title":"J. Comp. Physiol. B"},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0555","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00360-014-0881-5","article-title":"Cardiovascular function in large to small hibernators: bears to ground squirrels","volume":"185","author":"Nelson","year":"2015","journal-title":"J. Comp. Physiol. B"},{"issue":"Pt 24","key":"10.1016\/j.cbpa.2026.112015_bb0560","first-page":"4678","article-title":"Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction","volume":"216","author":"Nelson","year":"2013","journal-title":"J. Exp. Biol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0565","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.2460\/javma.2003.223.1170","article-title":"Evaluation of cardiac function in active and hibernating grizzly bears","volume":"223","author":"Nelson","year":"2003","journal-title":"J. Am. Vet. Med. Assoc."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0570","doi-asserted-by":"crossref","first-page":"H366","DOI":"10.1152\/ajpheart.00234.2008","article-title":"Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears","volume":"295","author":"Nelson","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0575","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1748-1716.1968.tb04316.x","article-title":"Difference in cardiac adrenergic innervation between hibernators and non-hibernating mammals","volume":"316","author":"Nielsen","year":"1968","journal-title":"Acta Physiol. Scand. Suppl."},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0580","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.cardiores.2006.05.026","article-title":"Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: co-operation with Src tyrosine kinase","volume":"71","author":"Obasanjo-Blackshire","year":"2006","journal-title":"Cardiovasc. Res."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0585","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0742-8413(87)90096-X","article-title":"Temperature sensitivity of cardiac muscarinic receptors in bat atria and ventricle","volume":"86","author":"O'Shea","year":"1987","journal-title":"Comp. Biochem. Physiol. C. Comp. Pharmacol. Toxicol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0590","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/jmor.1052170305","article-title":"Adrenergic innervation of the heart of the bat, Miniopterus schreibersii","volume":"217","author":"O\u2019Shea","year":"1993","journal-title":"J. Morphol."},{"issue":"4Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0595","first-page":"H876","article-title":"Innervation of bat heart: cholinergic and adrenergic nerves innervate all chambers","volume":"249","author":"O\u2019Shea","year":"1985","journal-title":"Am. J. Physiol."},{"issue":"21","key":"10.1016\/j.cbpa.2026.112015_bb0600","doi-asserted-by":"crossref","first-page":"jeb250970","DOI":"10.1242\/jeb.250970","article-title":"Chill-tolerant Drosophila species maintain electrogenic muscle membrane potential to resist cold-induced depolarization","volume":"228","author":"Overgaard","year":"2025","journal-title":"J. Exp. Biol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0605","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1076\/0924-3860(200007)38:3;1-5;FT195","article-title":"Morphological study of the heart innervation of bats Myotis daubentoni and Eptesicus serotinus (Microchiroptera: Vespertilionidae) during hibernation","volume":"38","author":"Pauziene","year":"2000","journal-title":"Eur. J. Morphol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0610","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1161\/01.RES.0000125629.72053.95","article-title":"Role of calcium cycling versus restitution in the mechanism of repolarization alternans","volume":"94","author":"Pruvot","year":"2004","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bib890","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00210-015-1199-x","article-title":"Diadenosine tetra- and pentaphosphates affect contractility and bioelectrical activity in the rat heart via P2 purinergic receptors","volume":"389","author":"Pustovit","year":"2016","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0615","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s13105-022-00902-8","article-title":"\u03b11-adrenergic receptors accompanied by GATA4 expression are related to proarrhythmic conduction and automaticity in rat interatrial septum","volume":"78","author":"Pustovit","year":"2022","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.cbpa.2026.112015_bb0620","doi-asserted-by":"crossref","first-page":"H148","DOI":"10.1152\/ajpheart.1997.273.1.H148","article-title":"Effects of hibernation on neural and endothelial control of mesenteric arteries of the golden hamster","volume":"273","author":"Ralevic","year":"1997","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0625","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0022-3565(24)37823-1","article-title":"Effects of hibernation and arousal from hibernation on mesenteric arterial responses of the golden hamster","volume":"287","author":"Ralevic","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.cbpa.2026.112015_bb0630","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00395-009-0012-8","article-title":"The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium","volume":"104","author":"Remme","year":"2009","journal-title":"Basic Res. Cardiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0635","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1152\/physiolgenomics.00159.2007","article-title":"Evolution of ventricular myocyte electrophysiology","volume":"35","author":"Rosati","year":"2008","journal-title":"Physiol. Genomics"},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0640","doi-asserted-by":"crossref","first-page":"R1044","DOI":"10.1152\/ajpregu.00688.2007","article-title":"Effects of polyunsaturated fatty acids on hibernation and torpor: a review and hypothesis","volume":"294","author":"Ruf","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0645","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/brv.12137","article-title":"Daily torpor and hibernation in birds and mammals","volume":"90","author":"Ruf","year":"2015","journal-title":"Biol. Rev. Camb. Philos. Soc."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0650","doi-asserted-by":"crossref","first-page":"508","DOI":"10.7150\/ijms.4476","article-title":"Body temperature during hibernation is highly correlated with a decrease in circulating innate immune cells in the brown bear (Ursus arctos): a common feature among hibernators?","volume":"10","author":"Sahdo","year":"2013","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.cbpa.2026.112015_bb0655","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1469-7793.2001.0495i.x","article-title":"Enhancement of ATP release in hindlimb sympathetic perivascular nerve of the golden hamster during hibernation","volume":"531","author":"Saito","year":"2001","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0660","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1113\/jphysiol.2001.013188","article-title":"Reversible impairment of endothelium-dependent relaxation in golden hamster carotid arteries during hibernation","volume":"540","author":"Saito","year":"2002","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0665","first-page":"197","article-title":"Ultrastructural localization of nitric oxide synthase and endothelin in the renal and mesenteric arteries of the golden hamster: differences during and after arousal from hibernation","volume":"6","author":"Saitongdee","year":"2009","journal-title":"J. Endothel. Cell Res."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0670","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1540-8167.1998.tb00897.x","article-title":"Hypoxia and hypothermia enhance spatial heterogeneities of repolarization in guinea pig hearts: analysis of spatial autocorrelation of optically recorded action potential durations","volume":"9","author":"Salama","year":"1998","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0675","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1134\/S0006297915030098","article-title":"Seasonal changes in isoform composition of giant proteins of thick and thin filaments and titin (connectin) phosphorylation level in striated muscles of bears (Ursidae, Mammalia)","volume":"80","author":"Salmov","year":"2015","journal-title":"Biochemistry (Mosc.)"},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0680","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0010-406X(70)90482-2","article-title":"Rate-temperature relationships in the isolated hearts of ground squirrels","volume":"33","author":"Senturia","year":"1970","journal-title":"Comp. Biochem. Physiol."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0685","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/CS20242144","article-title":"Distinct effects of obesity and diabetes on the action potential waveform and inward currents in rat ventricular myocytes","volume":"139","author":"Shmygol","year":"2025","journal-title":"Clin. Sci. (Lond.)"},{"issue":"11","key":"10.1016\/j.cbpa.2026.112015_bb0690","first-page":"1250","article-title":"Comparative characteristics of sarcoplasmic reticulum preparations from skeletal muscles of the ground squirrel Spermophilus undulatus, rats, and rabbits","volume":"64","author":"Shutova","year":"1999","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1016\/j.cbpa.2026.112015_bb0695","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/0011-2240(86)90029-5","article-title":"Effects of induced hypothermia on organ blood flow in a hibernator and a nonhibernator","volume":"23","author":"Sj\u00f6quist","year":"1986","journal-title":"Cryobiology"},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0700","first-page":"43","article-title":"Participation of 5'-AMP in cardiotropic effect of tissue extracts from hibernating animals","volume":"34","author":"Sukhova","year":"1998","journal-title":"Zh. Evol. Biokhim. Fiziol."},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0705","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0011-2240(88)90052-1","article-title":"Hypothermic effects on action potential and force production of hedgehog and guinea pig papillary muscles","volume":"25","author":"Svensson","year":"1988","journal-title":"Cryobiology"},{"issue":"4273","key":"10.1016\/j.cbpa.2026.112015_bb0710","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1126\/science.831261","article-title":"Antimetabolic extract from the brain of the hibernating ground squirrel Citellus tridecemlineatus","volume":"195","author":"Swan","year":"1977","journal-title":"Science"},{"key":"10.1016\/j.cbpa.2026.112015_bb0715","first-page":"420","article-title":"Mechanisms responsible for decreased glomerular filtration in hibernation and hypothermia","volume":"42","author":"Tempel","year":"1977","journal-title":"J. Appl. Physiol. Respir. Environ. Exercise Physiol."},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0720","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.gene.2012.04.004","article-title":"Myocyte enhancer factor-2 and cardiac muscle gene expression during hibernation in thirteen-lined ground squirrels","volume":"501","author":"Tessier","year":"2012","journal-title":"Gene"},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0725","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0008-6363(96)00018-1","article-title":"Ionic basis of the action potential prolongation in ventricular myocytes from Syrian hamsters with dilated cardiomyopathy","volume":"31","author":"Thuringer","year":"1996","journal-title":"Cardiovasc. Res."},{"issue":"10","key":"10.1016\/j.cbpa.2026.112015_bb0730","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1161\/CIRCULATIONAHA.119.042339","article-title":"Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy","volume":"141","author":"Toepfer","year":"2020","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.cbpa.2026.112015_bb0735","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/19336950.2021.1871815","article-title":"The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells","volume":"15","author":"Van de Sande","year":"2021","journal-title":"Channels (Austin)"},{"key":"10.1016\/j.cbpa.2026.112015_bb0740","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2024.102084","article-title":"Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears","volume":"92","author":"Van der Pijl","year":"2025","journal-title":"Mol. Metab."},{"key":"10.1016\/j.cbpa.2026.112015_bb0745","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3389\/fcvm.2018.00137","article-title":"Disease modifiers of inherited SCN5A channelopathy","volume":"5","author":"Verkerk","year":"2018","journal-title":"Front. Cardiovasc. Med."},{"issue":"11","key":"10.1016\/j.cbpa.2026.112015_bb0750","doi-asserted-by":"crossref","first-page":"4792","DOI":"10.1021\/acs.jproteome.5b00575","article-title":"Characterizing cardiac molecular mechanisms of mammalian hibernation via quantitative proteogenomics","volume":"14","author":"Vermillion","year":"2015","journal-title":"J. Proteome Res."},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0755","first-page":"995","article-title":"The behavior of titin and the proteins of its family from skeletal muscles of ground squirrel (Citellus undulatus) during hibernation and rats under conditions of simulated microgravity","volume":"49","author":"Vikhliantsev","year":"2004","journal-title":"Biofizika"},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0760","first-page":"1066","article-title":"Seasonal changes in the composition of the titin isoforms in muscles of hibernating ground squirrels","volume":"53","author":"Vikhliantsev","year":"2008","journal-title":"Biofizika"},{"key":"10.1016\/j.cbpa.2026.112015_bb0765","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1242\/jeb.145.1.339","article-title":"Basic functional properties of the cardiac muscle of the common shrew (Sorex araneus) and some other small mammals","volume":"145","author":"Vornanen","year":"1989","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0770","article-title":"Maximum heart rate of soricine shrews: correlation with contractile properties and myosin composition","volume":"262","author":"Vornanen","year":"1992","journal-title":"Am. J. Phys."},{"issue":"Pt16","key":"10.1016\/j.cbpa.2026.112015_bb0775","article-title":"Feeling the heat: source-sink mismatch as a mechanism underlying the failure of thermal tolerance","volume":"223","author":"Vornanen","year":"2020","journal-title":"J. Exp. Biol."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0780","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1006\/cryo.1997.2040","article-title":"Dependence of myocardial hypothermia tolerance on sources of activator calcium","volume":"35","author":"Wang","year":"1997","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2026.112015_bb0785","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF03183606","article-title":"Temperature dependence of intracellular free calcium in cardiac myocytes from rat and ground squirrel measured by confocal microscopy","volume":"42","author":"Wang","year":"1999","journal-title":"Sci. China C. Live Sci."},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0790","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF02879128","article-title":"Recording of calcium transient and analysis of calcium removal mechanisms in cardiac myocytes from rats and ground squirrels","volume":"43","author":"Wang","year":"2000","journal-title":"Sci. China C Life Sci."},{"key":"10.1016\/j.cbpa.2026.112015_bb0795","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1242\/jeb.205.19.2957","article-title":"Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators","volume":"205","author":"Wang","year":"2002","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0800","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1152\/ajplegacy.1971.221.5.1517","article-title":"Circulatory patterns of hibernators","volume":"221","author":"Wells","year":"1971","journal-title":"Am. J. Physiol."},{"issue":"5Pt2","key":"10.1016\/j.cbpa.2026.112015_bb0805","first-page":"R1214","article-title":"Disuse atrophy in the hibernating golden-mantled ground squirrel, Spermophilus lateralis","volume":"261","author":"Wickler","year":"1991","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0810","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF00688734","article-title":"Temperature sensitivity of the sodium pump in red cells from various hibernator and non-hibernator species","volume":"138","author":"Willis","year":"1980","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.cbpa.2026.112015_bb0815","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0011-2240(79)90014-2","article-title":"The effect of low temperature on the pressor response to noradrenaline in a hibernating (hedgehog) and a nonhibernating mammal (rat)","volume":"16","author":"Wisnes","year":"1979","journal-title":"Cryobiology"},{"issue":"14","key":"10.1016\/j.cbpa.2026.112015_bb0820","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2025333118","article-title":"Transcriptional regulation of intermolecular Ca2+ signaling in hibernating ground squirrel cardiomyocytes: the myocardin-junctophilin axis","volume":"118","author":"Yang","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/j.cbpa.2026.112015_bb0825","doi-asserted-by":"crossref","first-page":"H2219","DOI":"10.1152\/ajpheart.01096.2003","article-title":"Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals","volume":"286","author":"Yatani","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpa.2026.112015_bb0830","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1134\/S0012496609010074","article-title":"Changes in force-frequency relationships in cardiac papillary muscles of hibernating ground squirrels under cooling","volume":"424","author":"Zakharova","year":"2009","journal-title":"Dokl. Biol. Sci."},{"issue":"3","key":"10.1016\/j.cbpa.2026.112015_bb0835","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1086\/724688","article-title":"Cardiac rhythms and variation in hibernating arctic ground squirrels","volume":"96","author":"Zanetti","year":"2023","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.cbpa.2026.112015_bb0840","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0011-2240(84)90220-7","article-title":"Renal and cardiovascular effects of hibernation and hypothermia","volume":"21","author":"Zatzman","year":"1984","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2026.112015_bb0845","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/0011-2240(87)90041-1","article-title":"Seasonal variation of cardiovascular function in the marmot Marmota flaviventris","volume":"24","author":"Zatzman","year":"1987","journal-title":"Cryobiology"},{"key":"10.1016\/j.cbpa.2026.112015_bb0850","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0011-2240(89)90053-9","article-title":"Thickness of medial layers of arteries prior to and during hibernation","volume":"26","author":"Zatzman","year":"1989","journal-title":"Cryobiology"},{"issue":"1\u20132","key":"10.1016\/j.cbpa.2026.112015_bb0855","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11010-015-2605-x","article-title":"Expression of nuclear factor of activated T cells (NFAT) and downstream muscle-specific proteins in ground squirrel skeletal and heart muscle during hibernation","volume":"412","author":"Zhang","year":"2016","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.cbpa.2026.112015_bb0865","doi-asserted-by":"crossref","unstructured":"Zhou, Z.Q., Liu, B., Dryden, W.F., Wang, L.C., 1991. Cardiac mechanical restitution in active and hibernating Richardson's ground squirrel. Am. J. Physiol. 260 (2Pt2), R353\u2013358. doi:https:\/\/doi.org\/10.1152\/ajpregu.1991.260.2.R353.","DOI":"10.1152\/ajpregu.1991.260.2.R353"},{"issue":"5","key":"10.1016\/j.cbpa.2026.112015_bb0870","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.yjmcc.2008.07.015","article-title":"Nitric oxide signaling and the regulation of myocardial function","volume":"45","author":"Ziolo","year":"2008","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"8","key":"10.1016\/j.cbpa.2026.112015_bb0875","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00360-002-0295-7","article-title":"The parasympathetic nervous system: its role during torpor in the fat-tailed dunnart (Sminthopsis crassicaudata)","volume":"172","author":"Zosky","year":"2002","journal-title":"J. Comp. Physiol. B"},{"issue":"2","key":"10.1016\/j.cbpa.2026.112015_bb0880","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1078\/0944-2006-00108","article-title":"The parasympathetic nervous system and its influence on heart rate in torpid western pygmy possums, Cercatetus concinnus (Marsupialia: Burramyidae)","volume":"106","author":"Zosky","year":"2003","journal-title":"Zoology (Jena)"},{"issue":"4","key":"10.1016\/j.cbpa.2026.112015_bb0885","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00360-003-0335-y","article-title":"The cardiac innervation of a marsupial heterotherm, the fat-tailed dunnart (Sminthopsis crassicaudata)","volume":"173","author":"Zosky","year":"2003","journal-title":"J. Comp. Physiol. B"}],"container-title":["Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643326000504?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1095643326000504?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T14:56:31Z","timestamp":1783781791000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1095643326000504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":180,"alternative-id":["S1095643326000504"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpa.2026.112015","relation":{},"ISSN":["1095-6433"],"issn-type":[{"value":"1095-6433","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adaptations of the cardiovascular system in hibernating mammals.","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpa.2026.112015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112015"}}