{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:13:07Z","timestamp":1758121987878},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.cbpb.2012.06.004","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T14:16:59Z","timestamp":1340806619000},"page":"229-237","source":"Crossref","is-referenced-by-count":20,"title":["Molecular characterization of the GHRH\/GHRH-R and its effect on GH synthesis and release in orange-spotted grouper (Epinephelus coioides)"],"prefix":"10.1016","volume":"163","author":[{"given":"Yuehua","family":"Qian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aifen","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoran","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wensheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpb.2012.06.004_bb0005","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1210\/en.130.3.1097","article-title":"Expression of the growth hormone-releasing hormone gene and its peptide product in the rat ovary","volume":"130","author":"Bagnato","year":"1992","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0010","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1210\/jc.75.1.281","article-title":"Growth hormone-releasing hormone-like messenger ribonucleic acid and immunoreactive peptide are present in human testis and placenta","volume":"75","author":"Berry","year":"1992","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0015","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/301607a0","article-title":"Immunohistochemical detection of growth hormone-releasing factor in brain","volume":"301","author":"Bloch","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0167-0115(84)90025-9","article-title":"Topographical and ontogenetic study of the neurons producing growth hormone-releasing factor in human hypothalamus","volume":"8","author":"Bloch","year":"1984","journal-title":"Regul. Pept."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0025","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0196-9781(85)90104-4","article-title":"Central effects of growth hormone-releasing factor (GRF) on intestinal motility in dogs: involvement of dopaminergic receptors","volume":"6","author":"Bueno","year":"1985","journal-title":"Peptides"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0030","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1210\/me.12.5.750","article-title":"Identification of binding domains of the growth hormone-releasing hormone receptor by analysis of mutant and chimeric receptor proteins","volume":"12","author":"DeAlmeida","year":"1998","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0035","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1073\/pnas.81.5.1553","article-title":"Growth hormone-releasing factor regulates growth hormone mRNA in primary cultures of rat pituitary cells","volume":"81","author":"Gick","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0040","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/ng0793-227","article-title":"GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function","volume":"4","author":"Godfrey","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0045","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1126\/science.6812220","article-title":"Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly","volume":"218","author":"Guillemin","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0050","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2001-2-12-reviews3013","article-title":"Family-B G-protein-coupled receptors","volume":"2","author":"Harmar","year":"2001","journal-title":"Genome Biol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0055","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1210\/jc.80.10.2933","article-title":"Identification of alternatively spliced messenger ribonucleic acid encoding truncated growth hormone-releasing hormone receptor in human pituitary adenomas","volume":"80","author":"Hashimoto","year":"1995","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0060","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1006\/abbi.2000.2208","article-title":"Biological activities of two porcine growth hormone-releasing hormone receptor isoforms","volume":"387","author":"Hassan","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0065","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0167-4781(92)90488-L","article-title":"Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene","volume":"1129","author":"Hosoya","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0070","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1159\/000124579","article-title":"Ontogenesis of growth hormone-releasing hormone neurons in the rat hypothalamus","volume":"43","author":"Ishikawa","year":"1986","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0075","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1210\/endo-120-2-525","article-title":"Pre-and postnatal developmental changes in hypothalamic content of rat growth hormone-releasing factor","volume":"120","author":"Jansson","year":"1987","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0080","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ygcen.2010.09.011","article-title":"Growth differences and differential expression analysis of pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH) between the sexes in half-smooth tongue sole Cynoglossus semilaevis","volume":"170","author":"Ji","year":"2011","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0085","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.tem.2011.03.006","article-title":"Growth hormone-releasing hormone: not only a neurohormone","volume":"22","author":"Kiaris","year":"2011","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0090","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.1210\/en.2007-0441","article-title":"Evidence that ghrelin is as potent as growth hormone (GH)-releasing hormone (GHRH) in releasing GH from primary pituitary cell cultures of a nonhuman primate (Papio anubis), acting through intracellular signaling pathways distinct from GHRH","volume":"148","author":"Kineman","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0095","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1073\/pnas.0611008104","article-title":"Discovery of growth hormone-releasing hormones and receptors in nonmammalian vertebrates","volume":"104","author":"Lee","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0100","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ygcen.2005.04.018","article-title":"Molecular cloning, tissue distribution, and ontogeny of mRNA expression of growth hormone in orange-spotted grouper (Epinephelus coioides)","volume":"144","author":"Li","year":"2005","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0105","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/364208a0","article-title":"Molecular basis of the little mouse phenotype and implications for cell type-specific growth","volume":"364","author":"Lin","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0110","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/0006-291X(84)90309-7","article-title":"Synthesis and in vitro bioactivity of C-terminal deleted analogs of human growth hormone-releasing factor","volume":"123","author":"Ling","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0115","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1073\/pnas.81.14.4302","article-title":"Isolation, primary structure, and synthesis of human hypothalamic somatocrinin: growth hormone-releasing factor","volume":"81","author":"Ling","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0120","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1073\/pnas.82.1.63","article-title":"Gene encoding human growth hormone-releasing factor precursor: structure, sequence, and chromosomal assignment","volume":"82","author":"Mayo","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0125","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1210\/en.2005-1488","article-title":"A dominant-negative human growth hormone-releasing hormone (GHRH) receptor splice variant inhibits GHRH binding","volume":"147","author":"McElvaine","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0130","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jmb.2007.10.013","article-title":"Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain","volume":"374","author":"McKibbin","year":"2007","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0135","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1210\/en.138.6.2380","article-title":"Two protochordate genes encode pituitary adenylate cyclase-activating polypeptide and related family members","volume":"138","author":"McRory","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0140","doi-asserted-by":"crossref","first-page":"4300","DOI":"10.1210\/en.139.10.4300","article-title":"Distribution, characterization, and growth hormone-releasing activity of pituitary adenylate cyclase-activating polypeptide in the European eel, Anguilla anguilla","volume":"139","author":"Montero","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0145","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cbpb.2011.02.006","article-title":"Molecular and functional analyses of growth hormone-releasing hormone (GHRH) from olive flounder (Paralichthys olivaceus)","volume":"159","author":"Nam","year":"2011","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0150","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.cbpa.2008.06.037","article-title":"Central administration of growth hormone-releasing hormone triggers downstream movement and schooling behavior of chum salmon (Oncorhynchus keta) fry in an artificial stream","volume":"152","author":"Ojima","year":"2009","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0155","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/0092-8674(91)90067-9","article-title":"Identification of a Gs activator region of the beta 2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation","volume":"67","author":"Okamoto","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0160","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1210\/en.138.1.414","article-title":"Exon skipping in the gene encoding pituitary adenylate cyclase-activating polypeptide in salmon alters the expression of two hormones that stimulate growth hormone release","volume":"138","author":"Parker","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0165","doi-asserted-by":"crossref","first-page":"R147","DOI":"10.1152\/ajpregu.00494.2009","article-title":"Growth hormone-releasing hormone activates sleep regulatory neurons of the rat preoptic hypothalamus","volume":"298","author":"Peterfi","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0170","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1210\/er.21.6.619","article-title":"The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)\/glucagon superfamily","volume":"21","author":"Sherwood","year":"2000","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0175","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/303532a0","article-title":"Characterization of rat hypothalamic growth hormone-releasing factor","volume":"303","author":"Spiess","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.cbpb.2012.06.004_bb0180","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1677\/JOE-07-0167","article-title":"Identification of two novel chicken GHRH receptor splice variants: implications for the roles of aspartate 56 in the receptor activation and direct ligand receptor interaction","volume":"195","author":"Wang","year":"2007","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cbpb.2012.06.004_bb0185","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1210\/en.2006-1013","article-title":"Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor: evidence for a separate gene encoding GHRH in submammalian vertebrates","volume":"148","author":"Wang","year":"2007","journal-title":"Endocrinology"}],"container-title":["Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109649591200108X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109649591200108X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T08:55:08Z","timestamp":1542876908000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109649591200108X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S109649591200108X"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpb.2012.06.004","relation":{},"ISSN":["1096-4959"],"issn-type":[{"value":"1096-4959","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}