{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:56:16Z","timestamp":1791284176203,"version":"4.1.0"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.cbpb.2022.110731","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T13:38:23Z","timestamp":1646746703000},"page":"110731","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Aggravation of hepatic lipidosis in red-footed tortoise Chelonoidis carbonaria with age is associated with alterations in liver mitochondria"],"prefix":"10.1016","volume":"260","author":[{"given":"Marina R.","family":"Sartori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia D.C.","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger F.","family":"Castilho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anibal E.","family":"Vercesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpb.2022.110731_bb0005","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1046\/j.1365-2761.2003.00485.x","article-title":"Melano-macrophage centres and their role in fish pathology","volume":"26","author":"Agius","year":"2003","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.cbpb.2022.110731_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-511X-13-71","article-title":"Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus","volume":"13","author":"Azeez","year":"2014","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.cbpb.2022.110731_bb0015","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1002\/hep.26226","article-title":"Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease","volume":"58","author":"Begriche","year":"2013","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.mito.2021.01.007","article-title":"Mitochondrial metabolism and calcium homeostasis in the development of NAFLD leading to hepatocellular carcinoma","volume":"58","author":"Bhowmick","year":"2021","journal-title":"Mitochondrion"},{"key":"10.1016\/j.cbpb.2022.110731_bb0025","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0891-5849(98)00225-1","article-title":"Lipoxygenase\/H2O2-catalyzed oxidation of dihdroxyindoles: synthesis of melanin pigments and study of their antioxidant properties","volume":"26","author":"Blarzino","year":"1999","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1600-0749.1996.tb00108.x","article-title":"Melanomacrophage aggregations and their age relationships in the yellow mud turtle, Kinosternon flavescens (Kinosternidae)","volume":"9","author":"Christiansen","year":"1996","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.cbpb.2022.110731_bb0035","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1001\/jama.282.17.1659","article-title":"Alterations in liver ATP homeostasis in human nonalcoholic SteatohepatitisA pilot study","volume":"282","author":"Cortez-Pinto","year":"1999","journal-title":"JAMA"},{"issue":"Pt 2","key":"10.1016\/j.cbpb.2022.110731_bb0040","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1042\/bj3410233","article-title":"The mitochondrial permeability transition pore and its role in cell death","volume":"341","author":"Crompton","year":"1999","journal-title":"Biochem. J."},{"key":"10.1016\/j.cbpb.2022.110731_bb0045","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19041065","article-title":"Non-metastatic cutaneous melanoma induces chronodisruption in central and peripheral circadian clocks","volume":"19","author":"de Assis","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpb.2022.110731_bb0050","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.yexmp.2011.07.003","article-title":"Liver mitochondrial function and redox status in an experimental model of non-alcoholic fatty liver disease induced by monosodium l-glutamate in rats","volume":"91","author":"de Lazarin","year":"2011","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0055","first-page":"213","article-title":"Melanic pigmentation in ectothermic vertebrates: occurrence and function melanophores: color changes. Melanin biosynthesis","author":"De Oliveira","year":"2012","journal-title":"Funct. Heal. Eff."},{"key":"10.1016\/j.cbpb.2022.110731_bb0060","first-page":"711","article-title":"Lipid storage and utilization in reptiles","volume":"16","author":"Derickson","year":"1976","journal-title":"Integr. Comp. Biol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0065","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1053\/ax.2000.7136","article-title":"Reptile hepatic lipidosis","volume":"9","author":"Divers","year":"2000","journal-title":"Semin. Avian Exot. Pet Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0070","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S1094-9194(17)30140-8","article-title":"Nutrition of captive reptiles","volume":"2","author":"Donoghue","year":"1999","journal-title":"Vet. Clin. North Am. Exot. Anim. Pract."},{"key":"10.1016\/j.cbpb.2022.110731_bb0140","first-page":"633","article-title":"Diagnostic value of hepatic enzymes, triglycerides and serum proteins for the detection of hepatic lipidosis in chelonoidis carbonaria in captivity","volume":"8","author":"Dutra","year":"2014","journal-title":"J Life Sci"},{"key":"10.1016\/j.cbpb.2022.110731_bb0075","doi-asserted-by":"crossref","first-page":"554","DOI":"10.2307\/1564252","article-title":"Seasonal changes in reproductive condition and energy stores in Cnemidophorus sexlineatus","volume":"20","author":"Etheridge","year":"1986","journal-title":"J. Herpetol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0080","doi-asserted-by":"crossref","first-page":"3093","DOI":"10.2741\/1765","article-title":"Apoptosis in alcoholic and nonalcoholic steatohepatitis","volume":"10","author":"Feldstein","year":"2005","journal-title":"Front. Biosci."},{"key":"10.1016\/j.cbpb.2022.110731_bb0085","series-title":"Safranine as a Fluorescent Probe for the Evaluation of Mitochondrial Membrane Potential in Isolated Organelles and Permeabilized Cells, Mitochondrial Bioenergetics: Methods and Protocols (Methods in Molecular Biology)","volume":"vol. 810","author":"Figueira","year":"2012"},{"key":"10.1016\/j.cbpb.2022.110731_bb0090","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1089\/ars.2012.4729","article-title":"Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health","volume":"18","author":"Figueira","year":"2013","journal-title":"Antioxidants Redox Signal."},{"issue":"1","key":"10.1016\/j.cbpb.2022.110731_bib386","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpb.2022.110731_bb0095","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S1262-3636(07)70098-8","article-title":"The ins and outs of mitochondrial dysfunction in NASH","volume":"30","author":"Fromenty","year":"2004","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.cbpb.2022.110731_bb0100","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1002\/hep4.1271","article-title":"Mitochondrial oxidative stress and antioxidants balance in fatty liver disease","volume":"2","author":"Garc\u00eda-Ruiz","year":"2018","journal-title":"Hepatol. Commun."},{"key":"10.1016\/j.cbpb.2022.110731_bb0105","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/hep.21313","article-title":"Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob\/ob mice","volume":"44","author":"Garc\u00eda-Ruiz","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0110","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1021\/pr9011427","article-title":"Mitochondrial complex i subunits are decreased in murine nonalcoholic fatty liver disease: implication of peroxynitrite","volume":"9","author":"Garc\u00eda-Ruiz","year":"2010","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.cbpb.2022.110731_bb0115","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1590\/S0102-09352004000100020","article-title":"Hepatic cirrhosis in a red-foot tortoise (Geochelone carbonaria). A case report","volume":"56","author":"Guedes","year":"2004","journal-title":"Arq. Bras. Med. Vet. Zootec."},{"key":"10.1016\/j.cbpb.2022.110731_bb0120","doi-asserted-by":"crossref","DOI":"10.1152\/ajpcell.1990.258.5.C755","article-title":"Mechanisms by which mitochondria transport calcium","volume":"258","author":"Gunter","year":"1990","journal-title":"Am. J. Physiol. - Cell Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0125","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00360-002-0271-2","article-title":"Patterns of lipid storage and mobilisation in the female green sea turtle (Chelonia mydas)","volume":"172","author":"Hamann","year":"2002","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpb.2022.110731_bb0130","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1023\/A:1005568630151","article-title":"Control of the mitochondrial permeability transition pore by high-affinity ADP binding at the ADP\/ATP translocase in permeabilized mitochondria","volume":"32","author":"Haworth","year":"2000","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.cbpb.2022.110731_bb0135","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/icb\/42.1.43","article-title":"Reproductive effort and reproductive nutrition of female desert tortoises: essential field Methods1","volume":"42","author":"Henen","year":"2002","journal-title":"Integr. Comp. Biol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0145","series-title":"Reptile Medicine and Surgery","first-page":"806","article-title":"Hepatic lipidosis","author":"Hernandez-Divers","year":"2006"},{"key":"10.1016\/j.cbpb.2022.110731_bb0150","first-page":"40","article-title":"Regulation of vitellogenesis in reptiles","volume":"38","author":"Ho","year":"1982","journal-title":"Herpetologica"},{"key":"10.1016\/j.cbpb.2022.110731_bb0155","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1152\/ajpendo.00272.2010","article-title":"Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?","volume":"299","author":"Hodson","year":"2010","journal-title":"Am. J. Physiol. - Endocrinol. Metab."},{"key":"10.1016\/j.cbpb.2022.110731_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/030098589403100101","article-title":"Chlamydiosis in mariculture-reared green sea turtles (Chelonia mydas)","volume":"31","author":"Homer","year":"1994","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0165","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2019.00962","article-title":"Adenosine monophosphate-activated protein kinase signaling regulates lipid metabolism in response to salinity stress in the red-eared slider turtle Trachemys scripta elegans","volume":"10","author":"Hong","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0170","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.18632\/aging.101887","article-title":"Hepatic lipid droplet breakdown through lipolysis during hibernation in Chinese soft-shelled turtle (Pelodiscus sinensis)","volume":"11","author":"Huang","year":"2019","journal-title":"Aging (Albany. NY)"},{"key":"10.1016\/j.cbpb.2022.110731_bb0175","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.2460\/javma.230.7.1049","article-title":"Coelioscopic-assisted prefemoral oophorectomy in chelonians","volume":"230","author":"Innis","year":"2007","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.cbpb.2022.110731_bb0180","doi-asserted-by":"crossref","first-page":"211","DOI":"10.2307\/1562982","article-title":"Fat and breeding cycles in two montane populations of Sceloporus occidentalis (Reptilia, Lacertilia, Iguanidae)","volume":"10","author":"Jameson","year":"1976","journal-title":"J. Herpetol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0185","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.vetmic.2014.02.029","article-title":"First report of a new alphaherpesvirus in a freshwater turtle (Pseudemys concinna concinna) kept in Germany","volume":"170","author":"Jungwirth","year":"2014","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0190","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.20701","article-title":"Design and validation of a histological scoring system for nonalcoholic fatty liver disease","volume":"41","author":"Kleiner","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0195","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.freeradbiomed.2009.05.004","article-title":"Mitochondria and reactive oxygen species","volume":"47","author":"Kowaltowski","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0200","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.freeradbiomed.2020.11.009","article-title":"Physiological evidence of mitochondrial permeability transition pore opening caused by lipid deposition leading to hepatic steatosis in db\/db mice","volume":"162","author":"Li","year":"2021","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0205","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2307\/1563765","article-title":"Fatbody and liver cycles in two tropical lizards Chamaeleo hohneli and Chamaeleo jacksoni (Reptilia, Lacertilia, Chamaeleonidae)","volume":"13","author":"Lin","year":"1979","journal-title":"J. Herpetol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0210","doi-asserted-by":"crossref","first-page":"4585","DOI":"10.1016\/S0021-9258(17)30051-0","article-title":"Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats","volume":"254","author":"Mannaerts","year":"1979","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpb.2022.110731_bb0215","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/j.jepm.2013.05.006","article-title":"Clinical update on diagnosis and management of disorders of the digestive system of reptiles","volume":"22","author":"Mans","year":"2013","journal-title":"J. Exot. Pet Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0220","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1638\/2014-0178R2.1","article-title":"Use of computed tomography for investigation of hepatic lipidosis in captive Chelonoidis carbonaria (Spix, 1824)","volume":"46","author":"Marchiori","year":"2015","journal-title":"J. Zoo Wildl. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0225","doi-asserted-by":"crossref","DOI":"10.1210\/endrev\/bnz009","article-title":"Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management","author":"Marjot","year":"2020","journal-title":"Endocrine Reviews"},{"key":"10.1016\/j.cbpb.2022.110731_bb0230","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/S0016-5085(99)70506-8","article-title":"Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity","volume":"116","author":"Matteoni","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbpa.2010.01.002","article-title":"Starvation physiology: reviewing the different strategies animals use to survive a common challenge","volume":"156","author":"McCue","year":"2010","journal-title":"Comp. Biochem. Physiol. - A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0240","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0300-9629(82)90372-3","article-title":"Seasonal changes of total lipids in the turtle Sternotherus odoratus","volume":"71","author":"McPherson","year":"1982","journal-title":"Comp. Biochem. Physiol. Part A Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2021.111131","article-title":"Starch and fiber intake effects on energy metabolism, growth, and carapacial scute pyramiding of red-footed tortoise hatchlings (Chelonoidis carbonaria)","volume":"265","author":"Mendoza","year":"2022","journal-title":"Comp. Biochem. Physiol. -Part A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0250","article-title":"The mitochondrial permeability transition pore: an evolving concept critical for cell life and death","volume":"3","author":"Morciano","year":"2021","journal-title":"Biol. Rev."},{"key":"10.1016\/j.cbpb.2022.110731_bb0255","first-page":"207","article-title":"Diet and food preferences of the tortoises Geochelone carbonaria and G. denticulata in northwestern Brazil","volume":"46","author":"Moskovits","year":"1990","journal-title":"Herpetologica"},{"key":"10.1016\/j.cbpb.2022.110731_bb0260","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.freeradbiomed.2017.09.026","article-title":"Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice","volume":"113","author":"Navarro","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbabio.2021.148428","article-title":"Mitochondrial proton leaks and uncoupling proteins","volume":"1862","author":"Nicholls","year":"2021","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"10.1016\/j.cbpb.2022.110731_bb0270","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3354\/dao063013","article-title":"Diseases and causes of mortality among sea turtles stranded in the Canary Islands, Spain (1998-2001)","volume":"63","author":"Or\u00f3s","year":"2005","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.cbpb.2022.110731_bb0275","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1002\/hep.1840380426","article-title":"Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis","volume":"38","author":"P\u00e9rez-Carreras","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0280","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.jhep.2005.03.004","article-title":"NASH: a mitochondrial disease","volume":"42","author":"Pessayre","year":"2005","journal-title":"J. Hepatol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0285","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1146\/annurev.es.09.110178.002511","article-title":"Morphological aspects and the ecological and mechanical consequences of fat deposition in wild vertebrates","volume":"9","author":"Pond","year":"1978","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"10.1016\/j.cbpb.2022.110731_bb0290","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1111\/brv.12288","article-title":"The physiology of lipid storage and use in reptiles","volume":"92","author":"Price","year":"2017","journal-title":"Biol. Rev."},{"key":"10.1016\/j.cbpb.2022.110731_bb0295","first-page":"G1135","article-title":"II. Cytochrome P-450 enzymes and oxidative stress","volume":"281","author":"Robertson","year":"2001","journal-title":"Am. J. Physiol. Liver Physiol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0300","doi-asserted-by":"crossref","first-page":"8494","DOI":"10.1021\/bi049803f","article-title":"Modulation of mitochondrial complex I activity by reversible Ca2+ and NADH mediated superoxide anion dependent inhibition","volume":"43","author":"Sadek","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.cbpb.2022.110731_bb0305","article-title":"Chip-calorimetric assessment of heat generation during Ca2+ uptake by digitonin-permeabilized Trypanosoma cruzi","author":"Sartori","year":"2021","journal-title":"J. Therm. Anal. Calorim."},{"key":"10.1016\/j.cbpb.2022.110731_bb0310","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.243532","article-title":"Enhanced resistance to Ca2+\u2212induced mitochondrial permeability transition in the long-lived red-footed tortoise Chelonoidis carbonaria","volume":"225","author":"Sartori","year":"2022","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0315","series-title":"Integrative Physiology of Fasting. Compr. Physiol., Major Reference Works","author":"Secor","year":"2016"},{"key":"10.1016\/j.cbpb.2022.110731_bb0320","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1042\/bj1140597","article-title":"The kinetic properties of citrate synthase from rat liver mitochondria","volume":"114","author":"Shepherd","year":"1969","journal-title":"Biochem. J."},{"key":"10.1016\/j.cbpb.2022.110731_bb0325","first-page":"101134","article-title":"Mitochondrial oxidative function in NAFLD: friend or foe?","author":"Shum","year":"2020","journal-title":"Mol. Metab."},{"key":"10.1016\/j.cbpb.2022.110731_bb0330","first-page":"6","article-title":"Impaired hepatic mitochondrial oxidation using the 13C-methionine breath test in patients with macrovesicular steatosis and patients with cirrhosis","volume":"9","author":"Spahr","year":"2003","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.cbpb.2022.110731_bb0335","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1002\/hep.23594","article-title":"Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection","volume":"51","author":"Starley","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0340","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2017.00827","article-title":"Melanomacrophage centers as a histological indicator of immune function in fish and other poikilotherms","volume":"8","author":"Steinel","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0345","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.foodchem.2008.11.015","article-title":"Physicochemical characterisation and antioxidant activity of melanin from the muscles of Taihe black-bone silky fowl (Gallus gallus domesticus Brisson)","volume":"114","author":"Tu","year":"2009","journal-title":"Food Chem."},{"key":"10.1016\/j.cbpb.2022.110731_bb0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2018.08.034","article-title":"Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition","volume":"129","author":"Vercesi","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpb.2022.110731_bb0355","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/hep.29788","article-title":"Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis","volume":"68","author":"Wang","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.cbpb.2022.110731_bb0360","doi-asserted-by":"crossref","first-page":"28","DOI":"10.5818\/1529-9651.11.2.28","article-title":"Endoscopic hepatic biopsy in Coahuilan box turtles, Terrapene coahuila","volume":"11","author":"West","year":"2001","journal-title":"J. Herpetol. Med. Surg."},{"key":"10.1016\/j.cbpb.2022.110731_bb0365","doi-asserted-by":"crossref","first-page":"16804","DOI":"10.1074\/jbc.R117.789271","article-title":"Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions","volume":"292","author":"Wong","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpb.2022.110731_bb0370","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S2213-8587(14)70032-4","article-title":"Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome","volume":"2","author":"Yki-J\u00e4rvinen","year":"2014","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.cbpb.2022.110731_bb0375","doi-asserted-by":"crossref","first-page":"16330","DOI":"10.1016\/S0021-9258(17)46227-2","article-title":"The oxidative inactivation of mitochondrial electron transport chain components and ATPase","volume":"265","author":"Zhang","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cbpb.2022.110731_bb0380","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0304-4157(95)00003-A","article-title":"The mitochondrial permeability transition","volume":"1241","author":"Zoratti","year":"1995","journal-title":"Biochim. Biophys. Acta - Rev. Biomembr."},{"key":"10.1016\/j.cbpb.2022.110731_bb0385","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1600-0749.1990.tb00276.x","article-title":"Distribution of Extracutaneous melanin pigment in Sparus auratus, Mugil cephalus, and Dicertranchus labrax (Pisces, Teleostei)","volume":"3","author":"Zuasti","year":"1990","journal-title":"Pigment Cell Res."}],"container-title":["Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096495922000197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096495922000197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:34:41Z","timestamp":1761086081000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096495922000197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":78,"alternative-id":["S1096495922000197"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpb.2022.110731","relation":{},"ISSN":["1096-4959"],"issn-type":[{"value":"1096-4959","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aggravation of hepatic lipidosis in red-footed tortoise Chelonoidis carbonaria with age is associated with alterations in liver mitochondria","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpb.2022.110731","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110731"}}