{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T20:27:39Z","timestamp":1790972859880,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.cbpc.2010.05.010","type":"journal-article","created":{"date-parts":[[2010,6,9]],"date-time":"2010-06-09T05:05:56Z","timestamp":1276059956000},"page":"338-345","source":"Crossref","is-referenced-by-count":151,"title":["Biomarkers as a tool to assess effects of chromium (VI): Comparison of responses in zebrafish early life stages and adults"],"prefix":"10.1016","volume":"152","author":[{"given":"In\u00eas","family":"Domingues","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhaul","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Koppe","family":"Grisolia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f3nia","family":"Mendo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.V.M.","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2010.05.010_bib1","first-page":"3973","article-title":"Study the effect of hexavalent chromium on some biochemical, citotoxicological and histopathological aspects of the Oreochromis spp. fish. Pak","volume":"10","author":"Abbas","year":"2007","journal-title":"J. Biol. Sci."},{"key":"10.1016\/j.cbpc.2010.05.010_bib2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0165-1218(95)90078-0","article-title":"Fish micronuclei for assessing genotoxicity in water","volume":"343","author":"Al-Sabti","year":"1995","journal-title":"Mut. Res.-Gen. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0269-7491(00)00221-9","article-title":"Environmental cadmium exposure and metabolic responses of the Nile tilapia, Oreochromis niloticus","volume":"114","author":"Almeida","year":"2001","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2010.05.010_bib5","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1006\/rtph.1997.1132","article-title":"Occurrences, uses, and properties of chromium","volume":"26","author":"Barnhart","year":"1997","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib6","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1080\/02772240600635985","article-title":"Oxidative stress and changes in locomotor behavior and gill morphology of Gambusia affinis exposed to chromium","volume":"88","author":"Begum","year":"2006","journal-title":"Toxicol. Environ. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib7","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib8","first-page":"87","article-title":"Towards an alternative for the acute fish LC50 test in chemical assessment: the fish embryo toxicity test goes multi-species \u2014 an update","volume":"22","author":"Braunbeck","year":"2005","journal-title":"Altex-Altern. Tierexp."},{"key":"10.1016\/j.cbpc.2010.05.010_bib9","article-title":"Background Paper on Fish Embryo Toxicity Assays","author":"Braunbeck","year":"2006"},{"key":"10.1016\/j.cbpc.2010.05.010_bib10","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1139\/f90-237","article-title":"Assessment of the piscine micronuclei test as in-situ biological indicator of chemical contaminant effects","volume":"47","author":"Carrasco","year":"1990","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.cbpc.2010.05.010_bib12","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.aquatox.2005.06.001","article-title":"Induction of micronuclei and nuclear abnormalities in Oreochromis niloticus following exposure to petroleum refinery and chromium processing plant effluents","volume":"74","author":"Cavas","year":"2005","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib13","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0921-8777(94)00043-6","article-title":"The kinetics of repair of oxidative DNA-damage (strand breaks and oxidized pyrimidines) in human cells","volume":"336","author":"Collins","year":"1995","journal-title":"Mut. Res.-DNA Repair"},{"key":"10.1016\/j.cbpc.2010.05.010_bib14","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ecoenv.2006.03.013","article-title":"Enzymatic inhibition and morphological changes in Hoplias malabaricus from dietary exposure to lead(II) or methylmercury","volume":"67","author":"Costa","year":"2007","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2010.05.010_bib15","first-page":"648","article-title":"Effects of copper and cadmium on cholinesterase and glutathione S-transferase activities of two marine gastropods (Monodonta lineata and Nucella lapillus)","volume":"145","author":"Cunha","year":"2007","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2010.05.010_bib16","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/etc.5620060108","article-title":"Ring test of an embryo-larval toxicity test with zebrafish (Brachydanio rerio) using chromium and zinc as toxicants","volume":"6","author":"Dave","year":"1987","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib17","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/etc.5620200621","article-title":"Evaluation of basal micronucleus frequency and hexavalent chromium effects in fish erythrocytes","volume":"20","author":"De Lemos","year":"2001","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib18","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0045-6535(01)00029-7","article-title":"Lactate dehydrogenase activity as an effect criterion in toxicity tests with Daphnia magna Straus","volume":"45","author":"Diamantino","year":"2001","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2010.05.010_bib19","series-title":"Report EPS 1\/RM\/12","article-title":"Guidance Document on Control of Toxicity Test Precision Using Reference Toxicants","year":"1990"},{"key":"10.1016\/j.cbpc.2010.05.010_bib20","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","article-title":"A new and rapid colorimetric determination of acetylcholinesterase activity","author":"Ellman","year":"1961","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib21","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/em.20291","article-title":"Evaluation of river water genotoxicity using the piscine micronucleus test","volume":"48","author":"Ergene","year":"2007","journal-title":"Environ. Mol. Mutag."},{"key":"10.1016\/j.cbpc.2010.05.010_bib22","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.aquatox.2005.09.011","article-title":"The effect of chronic chromium exposure on the health of Chinook salmon (Oncorhynchus tshawytscha)","volume":"76","author":"Farag","year":"2006","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib23","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1080\/13547500500264660","article-title":"Do metals inhibit acetylcholinesterase (AChE)? Implementation of assay conditions for the use of AChE activity as a biomarker of metal toxicity","volume":"10","author":"Frasco","year":"2005","journal-title":"Biomarkers"},{"key":"10.1016\/j.cbpc.2010.05.010_bib24","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1023\/A:1025457831923","article-title":"Effects of dimethoate and beta-naphthoflavone on selected biomarkers of Poecilia reticulata","volume":"26","author":"Frasco","year":"2002","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib25","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ecoenv.2004.10.015","article-title":"Development of a zebrafish 4-day toxicity of embryo-larval bioassay to assess chemicals","volume":"63","author":"Fraysse","year":"2006","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2010.05.010_bib26","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0027-5107(04)00239-8","article-title":"Sensitivity and variability of visual scoring in the comet assay \u2014 results of an inter-laboratory scoring exercise with the use of silver staining","volume":"556","author":"Garcia","year":"2004","journal-title":"Mut. Res.-Fund. Mol. M"},{"key":"10.1016\/j.cbpc.2010.05.010_bib27","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0742-8413(90)90143-W","article-title":"Use of the fish enzyme system in monitoring water quality: effects of mercury on tissue enzymes","volume":"97","author":"Gill","year":"1990","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2010.05.010_bib28","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.aquatox.2008.01.014","article-title":"The cytotoxicity and genotoxicity of hexavalent chromium in medaka (Oryzias latipes) cells","volume":"87","author":"Goodale","year":"2008","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib29","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s001289900286","article-title":"Acetylcholinesterase activity in juvenile Daphnia magna Strauss","volume":"57","author":"Guilhermino","year":"1996","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib30","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0076-6879(81)77053-8","article-title":"Assays for differentiation of glutathione S-transferase","volume":"77","author":"Habig","year":"1981","journal-title":"Meth. Enzymol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/mutage\/18.1.45","article-title":"Recommendations for conducting the in vivo alkaline comet assay","volume":"18","author":"Hartmann","year":"2003","journal-title":"Mutagenesis"},{"key":"10.1016\/j.cbpc.2010.05.010_bib32","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0165-7992(82)90136-1","article-title":"Induction of nuclear abnormalities (micronuclei) in the peripheral blood erythrocytes of the eastern mudminnow Umbra pygmaea by ethyl methanesulphonate","volume":"104","author":"Hooftman","year":"1982","journal-title":"Mutat. Res."},{"key":"10.1016\/j.cbpc.2010.05.010_bib33","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0147-6513(02)00119-7","article-title":"Invertebrate biomarkers: links to toxicosis that predict population decline","volume":"54","author":"Hyne","year":"2003","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2010.05.010_bib34","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.cbpc.2010.05.010_bib35","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1897\/05-460R.1","article-title":"A novel contact assay for testing genotoxicity of chemicals and whole sediments in zebrafish embryos","volume":"25","author":"Kosmehl","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib74","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s10646-004-1349-2","article-title":"Effects of exposure to a mixture of cadmium and chromium on detoxification enzyme (GST, P450-MO) activities in the frog Rana ridibunda","volume":"14","author":"Kostaropoulos","year":"2005","journal-title":"Ecotoxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib37","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2754\/avb200675020259","article-title":"Potassium dichromate as a reference substance for embryonic tests of toxicity in the common carp (Cyprinus carpio L.)","volume":"75","author":"Krejci","year":"2006","journal-title":"Acta Vet Brno"},{"key":"10.1016\/j.cbpc.2010.05.010_bib39","first-page":"196","article-title":"Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test?","volume":"149","author":"Lammer","year":"2009","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2010.05.010_bib40","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.aquatox.2008.01.007","article-title":"The effect of potassium dichromate on free radical processes in goldfish: Possible protective role of glutathione","volume":"87","author":"Lushchak","year":"2008","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1590\/S1415-47572006000100028","article-title":"Genotoxicity and mutagenicity of water contaminated with tannery effluents, as evaluated by the micronucleus test and comet assay using the fish Oreochromis niloticus and chromosome aberrations in onion root-tips","volume":"29","author":"Matsumoto","year":"2006","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib42","series-title":"Minitab Statistical Software (version 13)","author":"Minitab","year":"2000"},{"key":"10.1016\/j.cbpc.2010.05.010_bib43","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.etap.2008.02.010","article-title":"Acute toxicity impacts of hexavalent chromium on behavior and histopathology of gill, kidney and liver of the freshwater fish, Channa punctatus (Bloch)","volume":"26","author":"Mishra","year":"2008","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib44","series-title":"5th International Conference on Toxic Cyanoacteria, Noosa, Australia","first-page":"566","article-title":"Comparative sensitivity of embryo-larval toxicity assays with African catfish (Clarias gariepinus) and zebrafish (Danio rerio)","author":"Nguyen","year":"2001"},{"key":"10.1016\/j.cbpc.2010.05.010_bib45","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s00244-001-0007-4","article-title":"Embryo-larval toxicity tests with the African catfish (Clarias gariepinus): comparative sensitivity of endpoints","volume":"42","author":"Nguyen","year":"2002","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib46","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/j.marpolbul.2006.05.017","article-title":"Mutation analysis of ras gene in the liver of European eel (Anguilla anguilla L.) exposed to benzo[a]pyrene","volume":"52","author":"Nogueira","year":"2006","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.cbpc.2010.05.010_bib47","first-page":"893","article-title":"Micronuclei in red blood cells of armored catfish Hypostomus plecotomus exposed to potassium dichromate","volume":"7","author":"Normann","year":"2008","journal-title":"Afric. J. Biotechnol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib48","series-title":"Organization for Economic Co-Operation and Development","article-title":"Fish Acute Toxicity Test","author":"OECD","year":"1992"},{"key":"10.1016\/j.cbpc.2010.05.010_bib49","series-title":"Organization for Economic Co-Operation and Development","doi-asserted-by":"crossref","DOI":"10.1787\/dcr-2003-en","article-title":"Test no 202: Daphnia sp., Acute Immobilization Test","author":"OECD","year":"2004"},{"key":"10.1016\/j.cbpc.2010.05.010_bib50","series-title":"Organization for Economic Co-Operation and Development","doi-asserted-by":"crossref","DOI":"10.1787\/9789264025578-en","article-title":"Fish Embryo Toxicity Test","author":"OECD","year":"2006"},{"key":"10.1016\/j.cbpc.2010.05.010_bib51","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s11356-009-0119-3","article-title":"Effects of Triclosan on zebrafish early-life stages and adults","volume":"16","author":"Oliveira","year":"2009","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.cbpc.2010.05.010_bib52","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/etc.5620200815","article-title":"Variability in acetylcholinesterase and glutathione S-transferase activities in Chironomus riparius Meigen deployed in situ at uncontaminated field sites","volume":"20","author":"Olsen","year":"2001","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib53","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1897\/07-281R.1","article-title":"Changes in serum biochemical parameters of freshwater fish Oreochromis niloticus following prolonged metal (Ag, Cd, Cr, Cu, Zn) exposures","volume":"27","author":"Oner","year":"2008","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10695-006-9111-8","article-title":"Effects of lead nitrate on the activity of metabolic enzymes during early developmental stages of the African catfish, Clarias gariepinus (Burchell, 1822)","volume":"33","author":"Osman","year":"2007","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2010.05.010_bib55","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.cbi.2008.05.014","article-title":"Effects of exposure to multiple trace metals on biochemical, histological and ultrastructural features of gills of a freshwater fish, Channa punctata Bloch","volume":"174","author":"Pandey","year":"2008","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbpc.2010.05.010_bib58","first-page":"221","article-title":"Multiple biomarker response in rainbow trout during exposure to hexavalent chromium","volume":"138","author":"Roberts","year":"2004","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2010.05.010_bib60","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0013-9351(84)90103-8","article-title":"Effect of mercuric-chloride on some biochemical and physiological-parameters of the fresh-water murrel Channa-punctatus","volume":"34","author":"Sastry","year":"1984","journal-title":"Environ. Res."},{"key":"10.1016\/j.cbpc.2010.05.010_bib61","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/aheh.200300554","article-title":"Assessment of cyto- and genotoxic effects of a variety of chemicals using Saccharomyces cerevisiae","volume":"33","author":"Schmitt","year":"2005","journal-title":"Acta Hydrochim. Hydrobiol."},{"key":"10.1016\/j.cbpc.2010.05.010_bib62","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s11356-008-0018-z","article-title":"The zebrafish embryo model in environmental risk assessment - applications beyond acute toxicity testing","volume":"15","author":"Scholz","year":"2008","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.cbpc.2010.05.010_bib63","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s10646-008-0221-1","article-title":"In vitro and in vivo effects of cadmium on cholinesterases in Nile tilapia fingerlings: implications for biomonitoring aquatic pollution","volume":"17","author":"Silva","year":"2008","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.cbpc.2010.05.010_bib64","series-title":"Sigma Stat for Windows (version 3.10)","author":"SPSS","year":"2004"},{"key":"10.1016\/j.cbpc.2010.05.010_bib67","first-page":"118","article-title":"Lactate dehydrogenase","volume":"vol. III","author":"Vassault","year":"1983"},{"key":"10.1016\/j.cbpc.2010.05.010_bib69","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/j.chemosphere.2009.06.005","article-title":"Acute effects of copper and mercury on the estuarine fish Pomatoschistus microps: linking biomarkers to behaviour","volume":"76","author":"Vieira","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2010.05.010_bib70","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.scitotenv.2008.01.052","article-title":"Acute effects of Benzo[a]pyrene, anthracene and a fuel oil on biomarkers of the common goby Pomatoschistus microps (Teleostei, Gobiidae)","volume":"395","author":"Vieira","year":"2008","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2010.05.010_bib72","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1023\/A:1022504826342","article-title":"Chromium in the environment: factors affecting biological remediation","volume":"249","author":"Zayed","year":"2003","journal-title":"Plant and Soil"},{"key":"10.1016\/j.cbpc.2010.05.010_bib73","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00128-003-0243-6","article-title":"Cadmium, chromium, and copper induce polychromatocyte micronuclei in carp (Cyprinus carpio L.)","volume":"72","author":"Zhu","year":"2004","journal-title":"Bull. Environ. Contam. Toxicol."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045610001110?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045610001110?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T08:26:15Z","timestamp":1544430375000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045610001110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":63,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S1532045610001110"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2010.05.010","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}