{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:01:43Z","timestamp":1766048503571,"version":"3.40.4"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000199","name":"United States Department of Agriculture (USDA)","doi-asserted-by":"crossref","award":["58-6408-2-009"],"award-info":[{"award-number":["58-6408-2-009"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006804","name":"University of Mississippi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.cbpc.2014.09.005","type":"journal-article","created":{"date-parts":[[2014,9,20]],"date-time":"2014-09-20T16:30:54Z","timestamp":1411230654000},"page":"90-100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Gene-specific disruption of endocannabinoid receptor 1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder (FASD) phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis"],"prefix":"10.1016","volume":"167","author":[{"given":"Asok K.","family":"Dasmahapatra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikhlas A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2014.09.005_bb0005","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1530-0277.1991.tb00553.x","article-title":"A revised conservative estimate of the incidence of FAS and economic impact","volume":"15","author":"Abel","year":"1992","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0010","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1089\/zeb.2012.0785","article-title":"Developmental effects of cannabinoids on zebrafish larvae","volume":"10","author":"Akhtar","year":"2013","journal-title":"Zebrafish"},{"issue":"5394","key":"10.1016\/j.cbpc.2014.09.005_bb0015","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1126\/science.282.5394.1711","article-title":"Zebrafish hox clusters and vertebrate genome evolution","volume":"282","author":"Amores","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0020","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1016\/j.lfs.2003.11.001","article-title":"MAP kinase signaling in diverse effects of ethanol","volume":"74","author":"Aroor","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/alcalc\/agh111","article-title":"Role of the endocannabinoid system in the development of tolerance to alcohol","volume":"40","author":"Basavarajappa","year":"2005","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0030","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1530-0277.1993.tb00721.x","article-title":"Molecular mechanism by human brain to fatty acid ethyl esters","volume":"17","author":"Bora","year":"1993","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0035","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/S0306-4522(97)00348-5","article-title":"Expression of the CB1 and CB2 receptor messenger RNAs during embryonic development in the rat","volume":"82","author":"Buckley","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0040","series-title":"Publication No. ADM 90-1711","first-page":"17","article-title":"Alcohol, tobacco and other drugs may harm the unborn","author":"Cook","year":"1990"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0045","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.cbpc.2005.01.007","article-title":"Expression of Adh8 mRNA is developmentally regulated in Japanese medaka (Oryzias latipes)","volume":"140","author":"Dasmahapatra","year":"2005","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0050","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1098\/rstb.2000.0787","article-title":"The neurobiology and evolution of cannabinoid signaling","volume":"356B","author":"Elphick","year":"2001","journal-title":"Philos. Trans. R. Soc. Lond."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0055","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.drugalcdep.2011.02.003","article-title":"Involvement of the endocannabinoid system in alcohol dependence: the biochemical, behavioral and genetic evidence","volume":"117","author":"Erdozain","year":"2011","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0060","first-page":"227","article-title":"Physiological responses in sons of alcoholics","volume":"21","author":"Finn","year":"1997","journal-title":"Alcohol Health Res. World"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0065","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.mod.2004.05.010","article-title":"Medaka and zebrafish: an evolutionary twin study","volume":"121","author":"Furutani-Seiki","year":"2004","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0070","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1161\/CIRCULATIONAHA.105.596130","article-title":"Cannabinoid-1 receptor antagonist, rimonabant, for management of obesity and related risks","volume":"114","author":"Gadde","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0075","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1432-1033.1995.tb20780.x","article-title":"Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations","volume":"232","author":"Galiegue","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0080","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1177\/15353702-0323006-07","article-title":"Alcohol teratogenesis: mechanisms of damage and strategies for invention","volume":"230","author":"Goodlett","year":"2005","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0085","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/1029842021000010884","article-title":"Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure","volume":"4","author":"Guerri","year":"2002","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0095","first-page":"77","article-title":"Feasibility of medaka (Oryzias latipes) as an animal model to study fetal alcohol spectrum disorder","volume":"vol. 6","author":"Haron","year":"2012"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0090","first-page":"287","article-title":"Modulation of ethanol toxicity by Asian ginseng (Panax ginseng) in Japanese rice fish (Oryzias latipes) embryogenesis","volume":"157","author":"Haron","year":"2013","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0100","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1124\/pr.54.2.161","article-title":"International Union of Pharmacology. XXVII. Classification of cannabinoid receptors","volume":"54","author":"Howlett","year":"2002","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0105","first-page":"273","article-title":"Disruption of circulation by ethanol promotes fetal alcohol spectrum disorder (FASD) in medaka (Oryzias latipes) embryogenesis","volume":"148","author":"Hu","year":"2008","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0110","first-page":"495","article-title":"Ethanol disrupts chondrification of the neurocranial cartilages in medaka embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1a2) promoter methylation","volume":"150","author":"Hu","year":"2009","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0115","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0196-8858(91)90017-D","article-title":"A time-efficient, linear-space local similarity algorithm","volume":"12","author":"Huang","year":"1991","journal-title":"Adv. Appl. Math."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0120","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1006\/dbio.1995.1289","article-title":"Temporal and spatial pattern of genes expression for the hatching enzyme in the teleost embryo, Oryzias latipes","volume":"171","author":"Inohaya","year":"1995","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0125","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.mod.2004.03.012","article-title":"Stages of normal development in the medaka Oryzias latipes","volume":"121","author":"Iwamatsu","year":"2004","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0130","first-page":"15","article-title":"Moderate drinking and reduced risk of heart disease","volume":"23","author":"Klatsky","year":"1999","journal-title":"Alcohol Res. Health"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0135","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuroscience.2005.10.069","article-title":"Distribution of cannabinoid receptor 1 in the CNS of zebrafish","volume":"138","author":"Lam","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0140","doi-asserted-by":"crossref","first-page":"500","DOI":"10.4161\/epi.4.7.9925","article-title":"Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation","volume":"4","author":"Liu","year":"2009","journal-title":"Epigenetics"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0145","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0022-3565(25)38654-4","article-title":"Localization of cannabinoid receptors and nonsaturable high- density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids","volume":"268","author":"Lynn","year":"1994","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0150","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/346561a0","article-title":"Structure of a cannabinoid receptor and functional expression of the cloned cDNA","volume":"346","author":"Matsuda","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0155","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.mce.2008.11.014","article-title":"A novel role for the endocannabinoid system during zebrafish development","volume":"299","author":"Migliarini","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0160","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1530-0277.2009.01126.x","article-title":"MicroRNAs: master regulators of ethanol abuse and toxicity?","volume":"34","author":"Miranda","year":"2010","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0165","doi-asserted-by":"crossref","first-page":"lb421","DOI":"10.1096\/fasebj.25.1_supplement.lb421","article-title":"Cb1 cannabinoid receptor regulates ethanol- mediated inhibition of neurogenesis","volume":"25","author":"Mukhopadhyay","year":"2011","journal-title":"FASEB J."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0170","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/365061a0","article-title":"Molecular characterization of a peripheral receptor for cannabinoids","volume":"365","author":"Munro","year":"1993","journal-title":"Nature"},{"year":"2009","series-title":"Five Year Strategic Plan. FY, 09\u201314","author":"NIAAA","key":"10.1016\/j.cbpc.2014.09.005_bb0175"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2012.00043","article-title":"Understanding alcoholism through microRNA signatures in brains of human alcoholics","volume":"3","author":"Nunez","year":"2012","journal-title":"Front. Genet."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0185","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.alcohol.2012.01.002","article-title":"A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research","volume":"46","author":"Pava","year":"2012","journal-title":"Alcohol"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0190","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/(SICI)1096-9926(199711)56:5<317::AID-TERA5>3.0.CO;2-U","article-title":"Incidence of fetal alcohol syndrome and prevalence of alcohol-related neurodevelopmental disorder","volume":"56","author":"Sampson","year":"1997","journal-title":"Teratology"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0195","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1006\/taap.1996.8034","article-title":"Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system","volume":"142","author":"Schatz","year":"1997","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0205","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/01.mol.0000245257.17764.b2","article-title":"Cannabinoid receptors in atherosclerosis","volume":"17","author":"Steffens","year":"2006","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0200","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1868-7083-5-14","article-title":"Reduced expression of brain cannabinoid receptor 1 (Cnr1) is coupled with an increased complementary micro-RNA (miR-26b) in a mouse model of fetal alcohol spectrum disorders","volume":"5","author":"Stringer","year":"2013","journal-title":"Clin. Epigent."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0210","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1523\/JNEUROSCI.3786-12.2013","article-title":"Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits","volume":"33","author":"Subbanna","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0215","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/bdrb.20072","article-title":"Japanese medaka (Oryzias latipes): developmental for the study of alcohol teratology","volume":"77","author":"Wang","year":"2006","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0220","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1126\/science.1063545","article-title":"Endocannabinoid signaling in the brain","volume":"296","author":"Wilson","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0225","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1021\/tx100205a","article-title":"Teratogenic effects of blue cohosh (Caulophyllum thalictroides) in Japanese medaka (Oryzias latipes) are probably mediated through GATA2\/EDN1 signaling pathways","volume":"23","author":"Wu","year":"2010","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.cbpc.2014.09.005_bb0230","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1006\/geno.1996.0406","article-title":"Molecular cloning of two cannabinoid type 1-like receptor genes from the puffer fish Fugu rubripes","volume":"35","author":"Yamaguchi","year":"1996","journal-title":"Genomics"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0235","first-page":"21","article-title":"Alcohol and the cardiovascular system: molecular mechanisms for beneficial and harmful action","volume":"21","author":"Zakhari","year":"1997","journal-title":"Alcohol Health Res. World"},{"key":"10.1016\/j.cbpc.2014.09.005_bb0240","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.neuroscience.2010.07.004","article-title":"CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies","volume":"170","author":"Zurolo","year":"2010","journal-title":"Neuroscience"}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045614001276?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045614001276?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T18:56:12Z","timestamp":1746384972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045614001276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":48,"alternative-id":["S1532045614001276"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2014.09.005","relation":{},"ISSN":["1532-0456"],"issn-type":[{"type":"print","value":"1532-0456"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gene-specific disruption of endocannabinoid receptor 1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder (FASD) phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2014.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}