{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:32:02Z","timestamp":1790616722808,"version":"4.1.0"},"reference-count":105,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.cbpc.2016.01.001","type":"journal-article","created":{"date-parts":[[2016,1,21]],"date-time":"2016-01-21T16:21:02Z","timestamp":1453393262000},"page":"55-67","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Comprehensive physiology and toxicology of ecdysogens \u2014 The metabolically activated porphyrin-ecdysteroid complexes in insects"],"prefix":"10.1016","volume":"181-182","author":[{"given":"Karel","family":"Sl\u00e1ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halina","family":"Zhylitskaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2016.01.001_bb0010","series-title":"Advances in Insect Physiology","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2806(08)60240-4","article-title":"Function and structure of polytene chromosomes during insect development","volume":"7","author":"Ashburner","year":"1970"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0015","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0039-128X(76)90053-2","article-title":"The in vitro synthesis and secretion of ecdysone by the ring gland of the fly Sarcophaga bullata","volume":"27","author":"Bollenbacher","year":"1976","journal-title":"Steroids"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0020","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0016-6480(78)90208-3","article-title":"Changes in ecdysone content during postembryonic development of the waxmoth, Galleria mellonella: the role of the ovary","volume":"34","author":"Bollenbacher","year":"1978","journal-title":"Gen. Comp. Endocrinol."},{"issue":"Suppl. 24","key":"10.1016\/j.cbpc.2016.01.001_bb0025","first-page":"1","article-title":"Recherches exp\u00e9rimentales sur le d\u00e9terminisme de la m\u00e9tamorphose chez les L\u00e9pidopt\u010dres","author":"Bounhiol","year":"1938","journal-title":"Bull. Biol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0030","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1515\/znb-1954-0601","article-title":"\u0170ber die Isolierung eines Metamorphose-Hormons der Insekten in kristallisierter Form","volume":"9B","author":"Butenandt","year":"1954","journal-title":"Z. Naturforsch."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0035","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/jez.1401310206","article-title":"Removal of prothoracic glands from the nymphal cockroach","volume":"131","author":"Chadwick","year":"1956","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0040","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0020-1790(86)90082-X","article-title":"Probable occurrence of ecdysteroid fatty acid esters in different classes of arthropods","volume":"16","author":"Connat","year":"1986","journal-title":"Insect Biochem."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0045","series-title":"Statistics","author":"Crawley","year":"2005"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0050","first-page":"1066","article-title":"Ecdysteroid titres during autonomous metamorphosis in a dermestid beetle. Z. Naturforsch. C","volume":"35","author":"Delbecque","year":"1980","journal-title":"Biochem. Biophys. Biol. Virol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/joe.1.06900","article-title":"Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals","volume":"191","author":"Dinan","year":"2006","journal-title":"J. Endourol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0060","series-title":"Ecdysone: Structure and Functions","first-page":"3","article-title":"Phytoecdysteroids: diversity, biosynthesis and distribution","author":"Dinan","year":"2009"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0065","doi-asserted-by":"crossref","first-page":"1215-1027","DOI":"10.1016\/S0965-1748(99)00077-6","article-title":"Effect of bisacylhyrazine ecdysteroid mimics (RH-5849 and RH-5992) on chromosomal puffing, imaginal disc proliferation and pupariation in larvae of Drosophila melanogaster","volume":"29","author":"Farka\u0161","year":"1999","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0070","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2183\/pjab1912.16.417","article-title":"Inuction of pupation in silkworm by transplanting the prothoracic gland","volume":"16","author":"Fukuda","year":"1940","journal-title":"Proc. Imp. Acad. Jpn."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0075","first-page":"171","article-title":"Die klassische Vorstellung der hormonalen Steuerung der Insekt-entwicklung im Lichte neuer experimenteller Tatsachen: Produktion von H\u00e4utungshormone ausserhalb der Prothorakaldr\u00fcse","volume":"82","author":"Gersch","year":"1978","journal-title":"Zool. Jb. Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0080","series-title":"Insect Endocrinology","author":"Gilbert","year":"2012"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0085","first-page":"397","article-title":"Aspects of researach on insect growth hormones","volume":"44","author":"Gilbert","year":"1971","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0090","series-title":"Insect Development: Morphogenesis, Molting and Metamorphosis","first-page":"306","article-title":"The juvenile hormones","author":"Goodman","year":"2009"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0095","first-page":"471","article-title":"Action of some derivatives of phytoecdysones on insects","volume":"39","author":"Harmatha","year":"1990","journal-title":"Symp. Biol. Hung."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0100","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF00591780","article-title":"Arthropod moulting hormones from Achyranthes and Cyathula","volume":"59","author":"Hikino","year":"1972","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0105","first-page":"341","article-title":"Effect of insect moulting hormones, ecdysterone and inokosterone, on tumor cells","volume":"60","author":"Hirono","year":"1969","journal-title":"GANN"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0110","series-title":"Proc. XIIth Ecdysone Workshop, Barcelona","first-page":"50","article-title":"Effects of ovariectomy and allatectomy on ecdysteroid synthesis and ecdysteroid titers during larval-adult development of Gryllus bimaculatus (Ensifera, Gryllidae)","author":"Hoffmann","year":"1996"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0115","series-title":"Progress in Ecdysone Research","author":"Hoffmann","year":"1980"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0120","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/0022-1910(76)90103-7","article-title":"Molting hormone titer changes and their significance during development of the Colorado beetle, Leptinotarsa decemlineata","volume":"22","author":"Hsiao","year":"1976","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0125","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1248\/cpb.17.335","article-title":"Screening results of plants for phytoecdysones","volume":"17","author":"Imai","year":"1969","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0130","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev-ento-120811-153700","article-title":"The juvenile hormone signaling pathway in insect development","volume":"58","author":"Jindra","year":"2013","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0135","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1016\/S0040-4039(00)90701-9","article-title":"Isolation of ecdysone (crustecdysone) from Polypodium vulgare L. rhizomes","volume":"18","author":"Jizba","year":"1967","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0140","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/BF00601742","article-title":"Ecdyson, das H\u00e4utungshormon der Insekten","volume":"53","author":"Karlson","year":"1966","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0145","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1351\/pac196714010075","article-title":"The chemistry of insect hormones and insect pheromones","volume":"14","author":"Karlson","year":"1967","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0150","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0022-1910(69)90216-9","article-title":"Die Inaktivierung des Ecdysons bei der Schmeissfliege Calliphora erythrocephala Meigen","volume":"15","author":"Karlson","year":"1969","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0155","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1002\/cber.19650980743","article-title":"Zur Chemie der Ecdysons. VI. Reaktionen des Ecdysonmolek\u00fcls","volume":"98","author":"Karlson","year":"1965","journal-title":"Chem. Ber."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0160","first-page":"14","article-title":"Phytoecdysteroids \u2014 biologically active polyhydroxysteroids","volume":"64","author":"Kholodova","year":"1979","journal-title":"Ukr. Biokhim. Zh."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0165","series-title":"Physiological Systems in Insects","author":"Klowden","year":"2007"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0028728","article-title":"Common and distinct roles of juveniole hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insects","volume":"6","author":"Konopova","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0175","series-title":"Ecdysone, from Chemistry to Mofe of Action","author":"Koolman","year":"1989"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0180","first-page":"702","article-title":"Stimulation of growth and development in Japanese quails after oral administration of ecdysteroid-containing diet","volume":"52","author":"Koudela","year":"1995","journal-title":"Experientia"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0185","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0022-1910(83)90031-8","article-title":"Effects of the ingested phytoecdysteroid on the growth and developmen of two lepidopterous larvae","volume":"29","author":"Kubo","year":"1983","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0190","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.foodchem.2010.10.039","article-title":"Ecdysteroids from Chenopodium quinoa Willd., an ancient Andean crop of high nutritional value","volume":"125","author":"Kumpun","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0195","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1673\/031.003.0701","article-title":"Practical uses for ecdysteroids in mammals including humans: an update","volume":"3","author":"Lafont","year":"2003","journal-title":"J. Insect Sci."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0200","series-title":"Insect Endocrinol.","first-page":"106","article-title":"Ecdysteroid chemistry and biochemistry","author":"Lafont","year":"2011"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0205","first-page":"309","article-title":"Comparison between the effects of 20-hydroxyecdysone and phytohormones on growth and development in plants","volume":"92","author":"Mach\u00e1\u010dkov\u00e1","year":"1995","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0210","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1254\/jjp.20.142","article-title":"Pharmacological studies of insect metamorphosing hormone: ponasterone A, ecdysterone, and inokosterone in the rat","volume":"20","author":"Matsuoka","year":"1970","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0215","first-page":"1796","article-title":"The role of the prothoracic gland in determining critical weights for metamorphosis in Drosophila melanogaster","volume":"16","author":"Mirth","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0220","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1351\/pac197125010167","article-title":"The ecdysones","volume":"25","author":"Nakanishi","year":"1971","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0225","first-page":"915","article-title":"Insect hormones: the structure of ponasterone A., an insect moulting hormone from the leaves of Podocarpus nakaii Hey","volume":"1966","author":"Nakanishi","year":"1966","journal-title":"Chem. Commun."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0230","series-title":"Insect Physiology and Biochemisstry","author":"Nation","year":"2002"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0235","series-title":"Insect Hormones","author":"Nijhout","year":"1994"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0240","series-title":"Insect Hormones","author":"Nov\u00e1k","year":"1966"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0245","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1248\/cpb.17.1352","article-title":"Stimulatory effect of insect metamorphosing steroids from ferns on protein synthesis in mouse liver","volume":"17","author":"Otaka","year":"1969","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0255","series-title":"Entwicklungsphysiologie der Insekten","author":"Pflugfelder","year":"1958"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0260","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/BF00738313","article-title":"Zur Frage der Bildesorgane des H\u00e4utungswirkstoffe bei Schmetterlingen","volume":"35","author":"Piepho","year":"1948","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0265","series-title":"Proc. Conf. Insect Chem. Ecol., T\u00e1bor, Academia, Prague","first-page":"227","article-title":"Action of some new synthetic derivatives of phytoecdysones on insects","author":"P\u00ed\u0161","year":"1990"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0270","series-title":"Metamorphosis, Postembryonic Reprogramming of Gene Expession in Amphibian and Insect Cells","first-page":"223","article-title":"Molecular aspects of juvenile hormone action in insect metamorphosis","author":"Riddiford","year":"1996"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0275","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.ygcen.2012.06.001","article-title":"How does juvenile hormone control metamorphosis and reproduction?","volume":"179","author":"Riddiford","year":"2012","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0280","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.ibmb.2003.06.001","article-title":"Insights into the molecular basis of the hormonal control of molting and metamorphosis from Manduca sexta and Drosophila melanogaster","volume":"33","author":"Riddiford","year":"2003","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0285","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/arch.940180103","article-title":"Ecdysteroid synthesis and molting by the tobacco hornworm, Manduca sexta, in the absence of prothoracic glands","volume":"18","author":"Sakurai","year":"1991","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0290","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1303\/aez.3.49","article-title":"Ecdysone activity of plant-originated moulting hormones applied on the body surface of lepidopterous larvae","volume":"3","author":"Sato","year":"1968","journal-title":"Appl. Entomol. Zool."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0295","first-page":"142","article-title":"Action of ecdysone on ligated larvae of Galleria mellonella L. (Lepidoptera): induction of development","volume":"69","author":"Sehnal","year":"1972","journal-title":"Acta Entomol. Bohemoslov."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0300","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/0022-1910(66)90022-9","article-title":"The effect of corpus allatum hormone on respiratory metabolism during larval development and metamorphosis of Galleria mellonella L","volume":"12","author":"Sehnal","year":"1966","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0305","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0022-1910(88)90067-4","article-title":"Prothoracic glands and ecdysteroid titre in Galleria mellonella larvae","volume":"34","author":"Sehnal","year":"1988","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0310","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/0022-1910(81)90041-X","article-title":"Regulation and significance of of edysteroid titre fluctuation in lepidopterous larvae","volume":"27","author":"Sehnal","year":"1981","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0315","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1570-7458.1969.tb02565.x","article-title":"Plants as a source of materials with insect hormone activity","volume":"12","author":"Sl\u00e1ma","year":"1969","journal-title":"Entomol. Exp. Appl."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0325","series-title":"Herbivores, Their Interaction with Secondary Plant Metabolites","first-page":"673","article-title":"Insect hormones and antihormones in plants","author":"Sl\u00e1ma","year":"1979"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0330","first-page":"145","article-title":"Homeostatic function of ecdysteroids in ecdysis and oviposition","volume":"77","author":"Sl\u00e1ma","year":"1980","journal-title":"Acta Entomol. Bohemoslov."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0335","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0015-3796(80)80035-7","article-title":"Animal hormones and antihormones in plants","volume":"175","author":"Sl\u00e1ma","year":"1980","journal-title":"Biochem. Physiol. Pflanz."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0340","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1515\/znc-1982-0917","article-title":"Inverse relationships between ecdysteroid titres and total body metabolism in insects","volume":"37","author":"Sl\u00e1ma","year":"1982","journal-title":"Z. Naturforsch. C: Biochem. Biophys. Biol. Virol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0345","first-page":"161","article-title":"Illusive functions of the prothoracic gland in Galleria","volume":"80","author":"Sl\u00e1ma","year":"1983","journal-title":"Acta Entomol. Bohemoslov."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0350","first-page":"357","article-title":"Pharmacology of insect juvenile hormones","volume":"11","author":"Sl\u00e1ma","year":"1985","journal-title":"Compr. Insect Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0355","series-title":"Endocrinological Frontiers in Physiological Insect Ecology","first-page":"663","article-title":"The mysterious thoracic hormonal centre in insects","author":"Sl\u00e1ma","year":"1988"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0360","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF02980867","article-title":"Ecdysteroids: insect hormones, plant defensive factors or human medicine?","volume":"21","author":"Sl\u00e1ma","year":"1993","journal-title":"Phytoparasitica"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0365","first-page":"317","article-title":"Hormonal status of RH-5849 and RH-5992 synthetic ecdysone agonists (ecdysteroids) examined on several standard bioassay for ecdysteroids","volume":"92","author":"Sl\u00e1ma","year":"1995","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0370","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1093\/aesa\/91.2.168","article-title":"The prothoracic gland revisited","volume":"91","author":"Sl\u00e1ma","year":"1998","journal-title":"Ann. Entomol. Soc. Am."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0375","series-title":"Proc. 3rd Internat. Conf. on Urban Pests, Hronov, Czech Rep.","first-page":"9","article-title":"The history and present status of juvenoids","author":"Sl\u00e1ma","year":"1999"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0380","doi-asserted-by":"crossref","first-page":"141","DOI":"10.14411\/eje.2000.026","article-title":"Correlation between metabolic depression and ecdysteroid peak during embryogenesis of the desert locust, Schistocerca greagaria (Orthoptera:Acrididae)","volume":"97","author":"Sl\u00e1ma","year":"2000","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0385","first-page":"93","article-title":"The autonomic neuroendocrine system of insects (coelopulse)","volume":"56","author":"Sl\u00e1ma","year":"2004","journal-title":"Ups. J. Med. Sci. Suppl."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0390","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1163\/18749836-06041073","article-title":"Insect hormones: 50years after discovery of juvenile hormone analogues (juvenoids)","volume":"6","author":"Sl\u00e1ma","year":"2013","journal-title":"Terr. Arthropod Rev."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0395","first-page":"117","article-title":"What are ecdysteroids: insect hormones, essential mammalian D-vitamins or polar sterol used for growth in plants?","volume":"108","author":"Sl\u00e1ma","year":"2014","journal-title":"Chem. List."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0400","doi-asserted-by":"crossref","first-page":"567","DOI":"10.14411\/eje.2015.073","article-title":"A new look at the nature of insect juvenile hormone with particular reference to studies carried out in the Czech Republic","volume":"112","author":"Sl\u00e1ma","year":"2015","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0405","first-page":"355","article-title":"Insect hormones \u2014 ecdysteroids: their presence and actions in vertebrates","volume":"92","author":"Sl\u00e1ma","year":"1995","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0410","doi-asserted-by":"crossref","first-page":"221","DOI":"10.14411\/eje.2013.032","article-title":"Role of juvenile hormone in the hypermetabolic production of water revealed by the O2 consumption and thermovision images of larvae of insects fed a diet of dry food","volume":"110","author":"Sl\u00e1ma","year":"2013","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0415","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/0022-1910(84)90062-3","article-title":"Growth and respiratory enzyme activity in the prothoracic glands of Galleria","volume":"30","author":"Sl\u00e1ma","year":"1984","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0420","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0020-1790(76)90004-4","article-title":"Juvenogens, biochemically activated juvenoid complexes","volume":"6","author":"Sl\u00e1ma","year":"1976","journal-title":"Insect Biochem."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0425","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2307\/1539700","article-title":"The juvenile hormone V. The sensitivity of the bug, Pyrrhocoris apterus, to a hormonally active factor in American paperpulp","volume":"130","author":"Sl\u00e1ma","year":"1966","journal-title":"Biol. Bull."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0430","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0965-1748(93)90099-E","article-title":"Hormonal activityof ecdysteroids from certain asiatic plants","volume":"23","author":"Sl\u00e1ma","year":"1993","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0435","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/BF01925578","article-title":"Insect hormones in vertebrates; anabolic effects of 20-hydroxyecdysone in Japanese quail","volume":"52","author":"Sl\u00e1ma","year":"1996","journal-title":"Experientia"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0440","series-title":"Insect Hormones and Bioanalogues","first-page":"477","author":"Sl\u00e1ma","year":"1974"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0445","first-page":"367","article-title":"Effect of insect hormone, 20-hydroxyecdysone on growth and reproduction in mice","volume":"63","author":"Stopka","year":"1999","journal-title":"Acta Soc. Zool. Bohemoslov."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0450","first-page":"333","article-title":"Lipid composition of the seeds of an ecdysteroid-containing plant, Leuzea cathamoides (Willd.) DC (Asteraceae)","volume":"45","author":"Str\u00e1nsk\u00fd","year":"1998","journal-title":"Russ. J. Plant Physiol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0455","first-page":"137","article-title":"Steroids","volume":"10","author":"Svoboda","year":"1985","journal-title":"Compr. Insect Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0460","first-page":"16","article-title":"Mechanism of the anabolic action of phytoecdysteroids in mammals","volume":"11","author":"Syrov","year":"1984","journal-title":"Biol. Nauki (Moscow)"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0465","first-page":"107","article-title":"Anabolic properties of the phytoecdysone turkesterone and turkesterone tetraacetate in experiments on male rats","volume":"22","author":"Syrov","year":"1975","journal-title":"Probl. Endocrinol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0470","first-page":"32","article-title":"Anabolic effects of turkesterone and turkesteone tetraacetate","volume":"32","author":"Syrov","year":"1975","journal-title":"Dokl. Akad. Nauk Uzbek SSR"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0475","first-page":"466","article-title":"Phytoecdysones of Ajuga turkestanica, III. The structure of turkesterone","volume":"1975","author":"Usmanov","year":"1975","journal-title":"Khim. Prir. Soedin."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0480","series-title":"Modern Applied Statistics","author":"Venables","year":"2002"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0485","series-title":"Phytoecdysteroids","volume":"2003","author":"Volodin","year":"2003"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0490","series-title":"The Principles of Insect Physiology","author":"Wigglesworth","year":"1965"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0495","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/scientificamerican0767-13","article-title":"Third-generation pesticides","volume":"217","author":"Williams","year":"1967","journal-title":"Sci. Am."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0500","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/B978-0-12-654750-4.50012-8","article-title":"Hormonal interactions between plants and insects","volume":"1970","author":"Williams","year":"1970","journal-title":"Chem. Ecol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0505","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1590\/S0074-02761987000700010","article-title":"Midgut of lepidopteran pupae is a major depot of sequestered, mobilizable, ecdysteroids","volume":"82","author":"Williams","year":"1987","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.cbpc.2016.01.001_bb0510","first-page":"791","article-title":"Conference on insect plant interactions","volume":"18","author":"Williams","year":"1968","journal-title":"Biomed. Sci."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0515","doi-asserted-by":"crossref","first-page":"120","DOI":"10.2307\/1538411","article-title":"Physiology of insect diapause. IV. The brain and prothoracic glands as an endocrine system in the cecropia silkworm","volume":"103","author":"Williams","year":"1952","journal-title":"Biol. Bull."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0520","doi-asserted-by":"crossref","first-page":"344","DOI":"10.2307\/1539610","article-title":"Ecdysone and ecdysone analogues: their assay and action on pupae of Cynthia silkworms","volume":"134","author":"Williams","year":"1968","journal-title":"Biol. Bull."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0525","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1146\/annurev-ento-120811-153608","article-title":"Ecdysone control of developmental transitions: lessons from Drosophila research","volume":"58","author":"Yamanaka","year":"2013","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0530","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1016\/0006-2952(71)90431-X","article-title":"Effect of ecdysterone on hyperglycaemia in experimental animals","volume":"20","author":"Yoshida","year":"1971","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0535","first-page":"183","article-title":"Hormonally mediated insect-plant relationships: arthropod populations associated with ecdysteroid containing plant, Leuzea carthamoides (Asteraceae)","volume":"94","author":"Zelen\u00fd","year":"1997","journal-title":"Eur. J. Entomol."},{"key":"10.1016\/j.cbpc.2016.01.001_bb0540","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.steroids.2012.07.005","article-title":"Design and studies of novel polyoxysterol-based porphyrin conjugates","volume":"77","author":"Zhylitskaya","year":"2012","journal-title":"Steroids"}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045616300011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045616300011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T22:07:06Z","timestamp":1567548426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045616300011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":105,"alternative-id":["S1532045616300011"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2016.01.001","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comprehensive physiology and toxicology of ecdysogens \u2014 The metabolically activated porphyrin-ecdysteroid complexes in insects","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2016.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}