{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:26:18Z","timestamp":1790637978481,"version":"4.1.0"},"reference-count":115,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"African Research Excellence Fund","award":["MRF-157-0023-F-IBOR"],"award-info":[{"award-number":["MRF-157-0023-F-IBOR"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.cbpc.2019.108584","type":"journal-article","created":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T19:26:28Z","timestamp":1565033188000},"page":"108584","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Biochemical and endocrine-disrupting effects in Clarias gariepinus exposed to the synthetic pyrethroids, cypermethrin and deltamethrin"],"prefix":"10.1016","volume":"225","author":[{"given":"George","family":"Eni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oju R.","family":"Ibor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andem B.","family":"Andem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ene E.","family":"Oku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azubuike V.","family":"Chukwuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aina O.","family":"Adeogun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustine","family":"Arukwe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2019.108584_bb0005","first-page":"17","article-title":"Variations in plasma biochemical parameters of Clarias gariepinus exposed to sub-lethal concentrations of the methanolic extracts of Raphia Hookeri","volume":"30","author":"Adeogun","year":"2013","journal-title":"Trop. Vet."},{"key":"10.1016\/j.cbpc.2019.108584_bb0010","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.scitotenv.2015.09.061","article-title":"Intersex and alterations in reproductive development of a cichlid, Tilapia guineensis, from a municipal domestic water supply lake (Eleyele) in Southwestern Nigeria","volume":"541","author":"Adeogun","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2019.108584_bb0015","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.aquatox.2016.02.002","article-title":"Endocrine-disruptor molecular responses, occurrence of intersex and gonado-histopathological changes in tilapia species from a tropical freshwater dam (Awba Dam) in Ibadan","volume":"174","author":"Adeogun","year":"2016","journal-title":"Nigeria. Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0020","first-page":"7","article-title":"Endocrine disruptor responses in African sharptooth catfish (Clarias gariepinus) exposed to di-(\u22122-ethylhexyl)-phthalate","volume":"213","author":"Adeogun","year":"2018","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.cbpc.2019.108584_bb0025","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.etp.2009.11.008","article-title":"Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity","volume":"63","author":"Adesiyan","year":"2011","journal-title":"Experim. Toxicol. Pathol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0030","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.scitotenv.2014.11.047","article-title":"Assessment of the health status of wild fish inhabiting a cotton basin heavily impacted by pesticides in Benin (West Africa)","volume":"506-507","author":"Agbohessi","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2019.108584_bb0035","first-page":"157","article-title":"Pesticides used in cotton production affect reproductive development, endocrine regulation, liver status and offspring fitness in African catfish Clarias gariepinus (Burchell, 1822). Comp. Biochem. Physiol","volume":"167","author":"Agbohessi","year":"2015","journal-title":"Part C"},{"key":"10.1016\/j.cbpc.2019.108584_bb0040","first-page":"164","article-title":"Organichlorine, organophosphorus and pyrethroid pesticides residues in water and sediment samples from River Benue in Vinikilanf, Yola, Adamawa State, Nigeria using gas chromatography mass spectrometry equipped with electron capture detector","volume":"3","author":"Akan","year":"2015","journal-title":"Amer. J. Environ. Protect."},{"key":"10.1016\/j.cbpc.2019.108584_bb0045","first-page":"72","article-title":"Sensitive spectrophotometric determination of deltamethrin insecticides in its formulation and environmental samples","volume":"2","author":"Amin","year":"2015","journal-title":"Int. J. Adv Res. Chem. Scc."},{"key":"10.1016\/j.cbpc.2019.108584_bb0050","series-title":"Toxicological Profile for Pyrethrins and Pyrethroids","author":"ATSDR","year":"2001"},{"key":"10.1016\/j.cbpc.2019.108584_bb0055","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s10499-005-0615-5","article-title":"Acute tocixty of synthetic pyrethroid cypermethrin on the common carp (Cyprinus carpi L) embroys and larva","volume":"13","author":"Aydin","year":"2005","journal-title":"Aqua. Inter."},{"key":"10.1016\/j.cbpc.2019.108584_bb0060","first-page":"1","article-title":"Histopathological effects of cypermethrin on juvenile Nile tilapia (Oreochromis niloticus)","volume":"5","author":"Ayoola","year":"2007","journal-title":"Afri. J. Livestock Ext."},{"issue":"5","key":"10.1016\/j.cbpc.2019.108584_bb1000","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1080\/03601234.2012.648545","article-title":"Toxic effects of\u00a0deltamethrin\u00a0and \u03bb-cyhalothrin on Xenopus laevis tadpoles","volume":"47","author":"Aydin-Sinan","year":"2012","journal-title":"J. Environ. Sci. Health, Part B."},{"key":"10.1016\/j.cbpc.2019.108584_bb0065","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.aquatox.2014.11.022","article-title":"Molecular pathways associated with the intersex condition in rainbow darter (Etheostoma caeruleum) following exposures to municipal wastewater in the Grand River basin, ON","volume":"159","author":"Bahamonde","year":"2015","journal-title":"Canada. Part B. Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1023\/A:1013923308125","article-title":"Steroids in the control of reproductive function in fish","volume":"32","author":"Barannikova","year":"2002","journal-title":"Neurosci. Behav. Physiol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0075","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0278-6915(00)00152-6","article-title":"Risk assessment of the use of deltamethrin on bednets for the prevention of malaria","volume":"39","author":"Barlow","year":"2001","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0080","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/tox.20068","article-title":"Histological evidence of intersex in feral sharptooth catfish (Clarias gariepinus) from an estrogen polluted water source in Gauteng, South Africa","volume":"19","author":"Barnhoorn","year":"2004","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0085","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/j.ecoenv.2010.07.026","article-title":"Intersex in feral indigenous freshwater Oreochromis mossambicus, from various parts in the Luvuvhu River, Limpopo Province","volume":"73","author":"Barnhoorn","year":"2010","journal-title":"South Africa. Ecotoxicol. Environ. Safety"},{"key":"10.1016\/j.cbpc.2019.108584_bb0090","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.aquatox.2011.06.004","article-title":"Changes in gene transcription and whole organism responses in larval fathead minnow (Pimephales promelas) following short-term exposure to the synthetic pyrethroid bifenthrin","volume":"105","author":"Beggel","year":"2011","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0095","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.aquatox.2003.08.002","article-title":"Carbofuran insecticide induced biochemical alterations in liver and muscle tissues of the fish Clarias batrachus (linn) and recovery response","volume":"66","author":"Begum","year":"2004","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0100","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1023\/B:RUSE.0000025972.29638.46","article-title":"Comparative sensitivity to the insecticides deltamethrin and esfenvalerate of some aquatic insect larvae (Ephemeroptera and Odonata) and Daphnia magna","volume":"35","author":"Beketov","year":"2004","journal-title":"Russ. J. Ecol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0105","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3126\/on.v3i1.330","article-title":"Biochemical effects to toxicity of CCl 4 on rosy barbs (Puntius conchonius)","volume":"3","author":"Bhattacharya","year":"2005","journal-title":"Our Nature"},{"key":"10.1016\/j.cbpc.2019.108584_bb0110","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.forsciint.2017.10.040","article-title":"Fisrt report of a fish kill episode caused by pyrethroids in ITalaina freshwater","volume":"281","author":"Bille","year":"2017","journal-title":"Foren. Sci. Int."},{"key":"10.1016\/j.cbpc.2019.108584_bb0115","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/978-1-4613-8850-0_4","article-title":"Comparative toxicology of the pyrethroid insecticides","volume":"108","author":"Bradbury","year":"1989","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0120","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/etc.2019","article-title":"The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin","volume":"31","author":"Brander","year":"2012","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2019.108584_bb0125","doi-asserted-by":"crossref","first-page":"8977","DOI":"10.1021\/acs.est.6b02253","article-title":"Pyrethroid pesticides as endocrine disruptors: molecular mechanisms in vertebrates with a focus on fishes","volume":"50","author":"Brander","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0130","doi-asserted-by":"crossref","first-page":"382","DOI":"10.2460\/javma.1972.161.04.382","article-title":"Needle biopsy of the canine liver and correlation of laboratory data with histopathologic observations","volume":"161","author":"Brobst","year":"1972","journal-title":"Amer. Vet. Med. Ass. J."},{"key":"10.1016\/j.cbpc.2019.108584_bb0135","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.aquatox.2015.03.005","article-title":"The effect of bifenthrin on the dopaminergic pathway in juvenile rainbow trout (Oncorhynchus mykiss)","volume":"162","author":"Cargo","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0140","doi-asserted-by":"crossref","unstructured":"Chanon, K.E., Mendez-Galvan, J.F., Galindo-Jaramillo, J.M, Olguin-Bernal, H., Borja-Aburto, V.H., 2003. Cooperative actions to achieve malaria control without the use of DDT. Int. J. Hyg. Environ. Health 206, 387\u2013394.","DOI":"10.1078\/1438-4639-00235"},{"key":"10.1016\/j.cbpc.2019.108584_bb0145","first-page":"605","article-title":"Persistence of four pyrethroid insecticides in a mineral and organic soil. J. Environ. Sci","volume":"16","author":"Chapman","year":"1981","journal-title":"Health B"},{"key":"10.1016\/j.cbpc.2019.108584_bb0150","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/BF01622129","article-title":"Persistence of five pyrethroid insecticides in sterile, and natural, mineral and organic soil","volume":"26","author":"Chapman","year":"1981","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0155","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.taap.2005.06.022","article-title":"Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Nav 1.8 sodium channels expressed in Xenopus oocytes","volume":"211","author":"Choi","year":"2006","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0160","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1289\/ehp.9087255","article-title":"Mechanisms of toxic action and structure-activity relationships for Organochhorine and synthetic pyrethroids insecticides","volume":"87","author":"Coats","year":"1990","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.cbpc.2019.108584_bb0165","series-title":"Handbook of Histochemical Histopathological Techniques","first-page":"29","author":"Culling","year":"1974"},{"key":"10.1016\/j.cbpc.2019.108584_bb0170","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.aquatox.2014.07.007","article-title":"The role of P450 metabolism in the estrogenic activity of bifenthrin in fish","volume":"156","author":"DeGroot","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0175","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0269-7491(99)00263-8","article-title":"Biomarkers assessment in juvenile Cyprinus carpio exposed to waterborne cadmium","volume":"109","author":"Della Torre","year":"2000","journal-title":"Environ. Poll."},{"key":"10.1016\/j.cbpc.2019.108584_bb0180","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1006\/eesa.1999.1829","article-title":"Concentration effects of selected insecticides on brain acetylcholinesterase in the common carp (Cyprinus carpio L.). Ecotoxicol","volume":"45","author":"Demb\u00e9l\u00e8","year":"2000","journal-title":"Environ Saf."},{"key":"10.1016\/j.cbpc.2019.108584_bb0185","first-page":"91","article-title":"Effects of cypermethrin on some haematological, biochemical and histopathological parameters of common carp (Cyprinus carpio L.). Neuroendocrinol","volume":"27","author":"Dobsikova","year":"2006","journal-title":"Letters"},{"key":"10.1016\/j.cbpc.2019.108584_bb0190","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1006\/taap.1993.1227","article-title":"Differences in the neuroexcitatory actions of pyrethroid insecticides and sodium channel-spesific neurotoxins in rat and trout brain synaptosomes","volume":"123","author":"Eells","year":"1993","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0195","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1002\/ps.1616","article-title":"Applied aspects of neonicotinoid uses in crop protection","volume":"64","author":"Elbert","year":"2008","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.cbpc.2019.108584_bb0200","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.tiv.2006.09.019","article-title":"Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicol","volume":"21","author":"El-Demerdash","year":"2007","journal-title":"In Vitro"},{"key":"10.1016\/j.cbpc.2019.108584_bb0205","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/246169a0","article-title":"A photostable pyrethroid","volume":"246","author":"Elliott","year":"1973","journal-title":"Nature."},{"key":"10.1016\/j.cbpc.2019.108584_bb0210","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.etap.2013.04.019","article-title":"Effects of deltamethrin on biometric parameters and liver biomarkers in common carp (Cyprinus carpio L.)","volume":"38","author":"Ensibi","year":"2013","journal-title":"Environ. Toxicol. Pharmcol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0215","series-title":"Impact of Agricultural Pyrethroid Pesticides on Aquatic Fauna. Proceedings: Recent Research on the Environmental Chemistry and the Environmental Toxicology of Synthetic Pyrethroid Insecticides. Ottawa: Environment Canada","first-page":"7","author":"Ernst","year":"1987"},{"key":"10.1016\/j.cbpc.2019.108584_bb0220","series-title":"Deltamethrin","author":"EXTOXNET","year":"2003"},{"key":"10.1016\/j.cbpc.2019.108584_bb0225","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jhydrol.2010.08.012","article-title":"Presence of pyrethroid pesticides in water and sediments of Ebro River Delta","volume":"393","author":"Feo","year":"2010","journal-title":"J. Hydrol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0230","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/aja.2009.2","article-title":"Green tea polyphenols inhibit testosterone production in rat Leydig cells","volume":"11","author":"Figueiroa","year":"2009","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.cbpc.2019.108584_bb0235","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s10695-011-9466-3","article-title":"A comparative study on the effects of a pesticide (cypermethrin) and two metals (copper, lead) to serum biochemistry of Nile tilapia","volume":"37","author":"F\u0131rat","year":"2011","journal-title":"Oreochromis niloticus. Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2019.108584_bb0240","doi-asserted-by":"crossref","unstructured":"Forsgren, K.L., Riar,N., Schlenk,D. 2013. The effects of the pyrethroid insectice, bifenthrin, on steroid hormone levels and gonadal development on steelhead (Oncorhynchus mykiss) under hypersaline conditions. Gen. Comp. Endocrinol. 186, 101\u2013107.","DOI":"10.1016\/j.ygcen.2013.02.047"},{"key":"10.1016\/j.cbpc.2019.108584_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.marenvres.2012.08.012","article-title":"Liver histopathology on Baltic eelpout (Zoarces viviparous) \u2013 a baseline study for use in marine environmental monitoring","volume":"82","author":"Fricke","year":"2012","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.cbpc.2019.108584_bb0250","series-title":"Hepatology, a Textbook of Liver Disease","first-page":"833","article-title":"Liver function tests and the objective evaluation of the patient with liver disease","author":"Friedman","year":"1996"},{"key":"10.1016\/j.cbpc.2019.108584_bb0255","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0300-483X(02)00058-6","article-title":"Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: reduction of fluidity in the hydrophobic core and in glutathione peroxidase activity","volume":"175","author":"Gabbianelli","year":"2002","journal-title":"Toxicology"},{"key":"10.1016\/j.cbpc.2019.108584_bb0260","doi-asserted-by":"crossref","unstructured":"Garey, J., Wolff, M.S., 1998. Estrogenic and antoprogestagenic activities of pyrethroid insecticides. Biochem. Biophys. Re. Commun. 251, 855-859.","DOI":"10.1006\/bbrc.1998.9569"},{"key":"10.1016\/j.cbpc.2019.108584_bb0265","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1289\/ehp.99107173","article-title":"Estrogenic potential pf certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line","volume":"107","author":"Go","year":"1999","journal-title":"Environ. Health Prespect."},{"key":"10.1016\/j.cbpc.2019.108584_bb0270","series-title":"Harper's Illustrated Biochemistry (Harper's Biochemistry)","author":"Granner","year":"2006"},{"key":"10.1016\/j.cbpc.2019.108584_bb0275","first-page":"684","article-title":"The effects of propolis on gill, liver, muscle tissues of rainbow trout (Oncorhynchus mykiss) exposed to various concentrations of cypermethrin","volume":"13","author":"Gulhan","year":"2014","journal-title":"Iran. J. Fish. Sciences"},{"issue":"95","key":"10.1016\/j.cbpc.2019.108584_bb0280","first-page":"71","article-title":"Environmental chemistry, ecotoxicity, and fate of lambda-cyhalothrin","volume":"2008","author":"He","year":"2008","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0285","doi-asserted-by":"crossref","first-page":"4976","DOI":"10.1016\/j.scitotenv.2010.07.044","article-title":"Brain acetylcholinestrase, malondialdehyde and reduced glutathione as biomarkers of continuous exposure to tench, Tinca tinca, to carbofuran or deltamethrin","volume":"408","author":"Hernandez-Moreno","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2019.108584_bb0290","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.chemosphere.2016.08.087","article-title":"Gonado-histopathological changes, intersex and endocrine disruptor responses in relation to contaminant burden in Tilapia species from Ogun River, Nigeria","volume":"164","author":"Ibor","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2019.108584_bb0295","unstructured":"IPCS. 1990. Deltamethrin. In: environmental health criteria 97. Vol. 6. Geneva: International Programme on Chemical Safety, World Health Organization, 31\u201359."},{"key":"10.1016\/j.cbpc.2019.108584_bb0300","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s10661-015-4273-4","article-title":"Examining pyrethroids, carbamates and neonicotenoids in fish, water and sediments from the Indus River from potential health risks","volume":"187","author":"Jabeen","year":"2015","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.cbpc.2019.108584_bb0305","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.chemosphere.2010.09.072","article-title":"Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio)","volume":"82","author":"Jin","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2019.108584_bb0310","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1289\/ehp.8050","article-title":"Predicted exposures to steroid estrogens in U.K. Rivers correlate with widespread sexual disruption in wild fish populations. Environ","volume":"114","author":"Jobling","year":"2006","journal-title":"Health Perspect."},{"key":"10.1016\/j.cbpc.2019.108584_bb0315","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3923\/ijbc.2011.207.211","article-title":"Effect of Curacron toxicity on aminotransferases (ALT and AST) in the serum of the fish Cyprinus carpio","volume":"5","author":"Joseph","year":"2011","journal-title":"Int. J. Biol. Chem."},{"key":"10.1016\/j.cbpc.2019.108584_bb0320","doi-asserted-by":"crossref","unstructured":"Kale, M., Rathore, N., John, S., Bhatnagar, D., 1999. Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxicology letters 105, 197\u2013205.Kim, I,Y., Shin, J.H., Kim, H.S., Lee, S.J. Kang, I.H., Kim, T.S., Moon, H.J., Choi, K.S., Moon, A. and Han, S. Y., 2004. Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assay. J. Reprod. Develop. 50, 245\u2013255.","DOI":"10.1016\/S0378-4274(98)00399-3"},{"key":"10.1016\/j.cbpc.2019.108584_bb0325","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1262\/jrd.50.245","article-title":"Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assay","volume":"50","author":"Kim","year":"2004","journal-title":"J. Reprod. Develop."},{"key":"10.1016\/j.cbpc.2019.108584_bb0335","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1006\/pest.1999.2440","article-title":"In vivo effects of deltamethrin on dopamine neurochemistry and the role of augmented neurotransmitter release","volume":"65","author":"Kirby","year":"1999","journal-title":"Pest. Biochem. Physiol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0340","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0048-3575(88)90108-3","article-title":"Properties of Na channels in identified snail (Helix pomatia L.) neurones modified by deltamethrin","volume":"32","author":"Kiss","year":"1988","journal-title":"Pestic. Biochem. Phsiol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0345","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/(SICI)1099-1263(200001\/02)20:1<61::AID-JAT628>3.0.CO;2-3","article-title":"Disorders of male rat reproductive tract under the influence of atrazine","volume":"20","author":"Kniewald","year":"2000","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0350","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00128-008-9474-x","article-title":"Effects of deltamethrin on antioxidant status and oxidative stress biomarkers in freshwater mussel Unio elongatulus euchres","volume":"81","author":"K\u00f6pr\u00fcc\u00fc","year":"2008","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0355","doi-asserted-by":"crossref","unstructured":"Korkmaz, N., Cengiz, E.I., Unlu, E., Uysal,E. and Yanar M., 2009. Cypermethrin-induced histopatholigcal and biochemical changes in Nile tilapia (Oreochromis niloticus), and the protective and recupaerative effect of ascorbic acid. Environ, Toxicol. Pharmacol. 28, 198\u2013205.","DOI":"10.1016\/j.etap.2009.04.004"},{"key":"10.1016\/j.cbpc.2019.108584_bb0360","first-page":"679","article-title":"Histopathological changes in testis of the freshwater fish, Heteropneustes fossilis (Bloch) exposed to linear alkyl benzene sulphonate (LAS)","volume":"28","author":"Kumar","year":"2007","journal-title":"J. Environ. Biol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0365","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.chemosphere.2010.12.062","article-title":"Cypermethrin induced alterations in nitrogen metabolism in freshwater fishes","volume":"83","author":"Kumar","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2019.108584_bb0370","first-page":"3","article-title":"Experimental cypermethrin toxicity in rabbits-a clinical and patho-anatomical study","volume":"48","author":"Lakkawar","year":"2004","journal-title":"Folia Veterinaria"},{"key":"10.1016\/j.cbpc.2019.108584_bb0375","doi-asserted-by":"crossref","unstructured":"Laskowski, D.A. 2002. Physical and chemical properties of pyrethroids. In reviews of environmental contamination and toxicology (pp. 49-170). Springer, New York, NY.","DOI":"10.1007\/978-1-4757-4260-2_3"},{"key":"10.1016\/j.cbpc.2019.108584_bb0380","doi-asserted-by":"crossref","first-page":"20699","DOI":"10.1007\/s11356-017-9727-5","article-title":"Toxicity of cypermethrin and deltamethrin insecticides on embryos and larvae of Physalaemus gracilis (Anura: Leptodactylidae)","volume":"24","author":"Macagnan","year":"2017","journal-title":"Environ. Sci. Poll. Res."},{"key":"10.1016\/j.cbpc.2019.108584_bb0385","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s40071-017-0161-6","article-title":"Cypermethrin induced stress and changes in growth of freshwater fish Oreochromis niloticus","volume":"9","author":"Majumder","year":"2017","journal-title":"Int. Aquat. Res."},{"key":"10.1016\/j.cbpc.2019.108584_bb0390","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0048-9697(03)00445-5","article-title":"Direct and interacting toxicological effects on the waterflea (Daphnia magna) by natural organic matter, synthetic humic substances and cypermethrin","volume":"319","author":"Meems","year":"2004","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2019.108584_bb0395","first-page":"2489","article-title":"Ameliorative property of Delonix elata supplementary feed against cypermethrin induced serum biochemical changes in freshwater fish Cyprinus carpio (Linn)","volume":"5","author":"Meenambal","year":"2012","journal-title":"J. Pharm. Res."},{"key":"10.1016\/j.cbpc.2019.108584_bb0400","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/jes.2016.69","article-title":"Pyrtehtoid insecticides and their environmental degradates in repeated duplicate-diet solid food samples of 50 adults","volume":"28","author":"Morgan","year":"2018","journal-title":"J. Exp. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0405","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0300-483X(03)00207-5","article-title":"Different effects of type I and type II pyrethroids on erythrocyte plasma membrane properties and enzymatic activity in rats","volume":"191","author":"Nasuti","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.cbpc.2019.108584_bb0410","doi-asserted-by":"crossref","unstructured":"Naumann, K., 1990. Synthetic Pyrethroid insecticides: structures and properties. Chemistry of plant protection, Vol. 4, Springer-Verlag, NY.","DOI":"10.1007\/978-3-642-74849-3"},{"key":"10.1016\/j.cbpc.2019.108584_bb0415","author":"OECD"},{"key":"10.1016\/j.cbpc.2019.108584_bb0420","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1289\/ehp.7652","article-title":"Environmental health assessment of deltamethrin in a malarious area of Mexico: environmental persistence, toxicokinetics and genotoxicity in exposed children","volume":"113","author":"Ortiz-Perez","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.cbpc.2019.108584_bb0425","first-page":"34","article-title":"Vitellogenin induction and gonad abnormalities in male common carp (Cyprinus carpio linnaeus) introduced to Laguna De Bay","volume":"38","author":"Paraso","year":"2012","journal-title":"Philippines. Philipp. J. Vet. Anim. Sci."},{"key":"10.1016\/j.cbpc.2019.108584_bb0430","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.aquatox.2010.04.014","article-title":"Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator","volume":"99","author":"Pavlikova","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0435","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/jee\/tox343","article-title":"The effects of an ultra-low-volume application of etofenprox for mosquito management on Megachile rotundata (Hymenoptera: Megachilidae) larvae and adults in an agricultural setting","volume":"111","author":"Piccolomini","year":"2017","journal-title":"J. Econ. Entomol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0440","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ijheh.2015.01.002","article-title":"Pyrethroids: exposure and health effects \u2013 an update","volume":"218","author":"Saillenfait","year":"2015","journal-title":"Int J Hyg Envir Health"},{"key":"10.1016\/j.cbpc.2019.108584_bb0445","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1093\/toxsci\/57.1.54","article-title":"Lack of significant estrogenic or anti-estrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms","volume":"57","author":"Saito","year":"2000","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.cbpc.2019.108584_bb0450","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.pestbp.2014.08.004","article-title":"Sublethal toxicity of commercial formulations of deltamethrin and permethrin on selected biochemical constituents and enzyme activities in liver and muscle tissues of Anabas testudineus","volume":"115","author":"Sapana","year":"2014","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0455","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ecoenv.2011.11.041","article-title":"Reproductive biomarkers to identify endocrine disruption in Clarias gariepinus exposed to 4-nonylphenol","volume":"78","author":"Sayed Ael","year":"2012","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2019.108584_bb0460","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0147-6513(03)00009-5","article-title":"Oxidative stress biomarkers of exposure to deltamethrin in freshwater fish, Channa punctatus Bloch","volume":"56","author":"Sayeed","year":"2003","journal-title":"Ecotoxicol. Environ. Safety."},{"key":"10.1016\/j.cbpc.2019.108584_bb0465","series-title":"Green Trends in Insect Control","first-page":"94","article-title":"Pyrethrins and pyrethroid insecticides","volume":"vol. 11","author":"Schleier","year":"2011"},{"key":"10.1016\/j.cbpc.2019.108584_bb0470","first-page":"21","article-title":"Histomorphology of atretic follicles in rainbow trout (Oncorhynchus mykiss) from Kashmir","volume":"2","author":"Sharma","year":"2014","journal-title":"J. Entomol. Zool. Stud."},{"key":"10.1016\/j.cbpc.2019.108584_bb0475","unstructured":"Shaw, L. M., 1983. In: A Methods of Enzymatic Analysis (Bergmeyer, V., J. Bergmeyer and M. Grabl, Eds.) 3rd ed. Vol. 4, pp349\u2013364. Verlag Chemie, Deerfield Beach, Florida."},{"key":"10.1016\/j.cbpc.2019.108584_bb0480","first-page":"763","article-title":"A study on histopathological changes in the gonads of a freshwater teleost fish","volume":"3","author":"Shelke","year":"2014","journal-title":"A. mola exposed to the heavy metals. J. Glob. Biosci."},{"key":"10.1016\/j.cbpc.2019.108584_bb0485","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/tox.21920","article-title":"Early exposure to 17\u03b1-ethynylestradiol and diethylstilbestrol induces morphological changes and alters ovarian sterodogenic pathway enzyme gene expression in catfish, Clarias gariepinus","volume":"30","author":"Sridevi","year":"2013","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0490","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/tox.21920","article-title":"Early exposure to 17\u03b1-ethynylestradiol and diethylstilbestrol induces morphological changes and alters ovarian sterodogenic pathway enzyme gene expression in catfish, Clarias gariepinus","volume":"30","author":"Sridevi","year":"2013","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0495","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1177\/146642408610600510","article-title":"Pesticide usage and poisoning in Nigeria","volume":"106","author":"Sridhar","year":"1986","journal-title":"J. Royal Soci. Health"},{"key":"10.1016\/j.cbpc.2019.108584_bb0500","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s001289900558","article-title":"Impact of deltamethrin on serum calcium and inorganic phosphate of freshwater catfish, Heteropneustes fossilis","volume":"59","author":"Srivastava","year":"1997","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0505","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.chemosphere.2006.05.059","article-title":"Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay","volume":"66","author":"Sun","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2019.108584_bb0510","first-page":"58","article-title":"Acute and sublethal intoxification of deltamethrin in an Indian major carp, Labeo rohita","volume":"72","author":"Suvetha","year":"2015","journal-title":"Hormonal and enzymological responses. J. Basic Appl. Zool."},{"key":"10.1016\/j.cbpc.2019.108584_bb0515","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/j.1939-4640.2001.tb02164.x","article-title":"Atrazine effects on testosterone levels and androgen-dependent reproductive organs in peripubertal male rats","volume":"22","author":"Trentacoste","year":"2001","journal-title":"J. Androl."},{"key":"10.1016\/j.cbpc.2019.108584_bb0520","first-page":"193","article-title":"Toxic effects of cypermethrin in female rabbits","volume":"26","author":"Ullah","year":"2006","journal-title":"Pakist. Veterin. J."},{"key":"10.1016\/j.cbpc.2019.108584_bb0525","unstructured":"USEPA (United States Environmental Protection Agency).2022. Pyrethrins\/ Pyrethroids Cumulative Risk Assessment. Available at: http:\/\/epa.gov\/pesticides\/cumulative\/common mechgroups\/htm#pyrethrins. (2015)."},{"key":"10.1016\/j.cbpc.2019.108584_bb0530","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1080\/09593330903207194","article-title":"Histopathological effects of cypermethrin on gill, liver and kidney of fresh water fish Clarias gariepinus (Burchell, 1822), and recovery after exposure","volume":"30","author":"Velmurugan","year":"2009","journal-title":"Environ. Technol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0535","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0300-483X(98)00097-3","article-title":"In vitro genotoxic effects of the insecticide deltamethrin in human peripheral blood leukocytes: DNA damage (\u2018comet\u2019 assay) in relation to the induction of sister-chromatid exchanges and micronuclei","volume":"130","author":"Villarini","year":"1998","journal-title":"Toxicology"},{"key":"10.1016\/j.cbpc.2019.108584_bb0540","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.theriogenology.2009.04.016","article-title":"Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress","volume":"72","author":"Wang","year":"2009","journal-title":"Theriogenology"},{"key":"10.1016\/j.cbpc.2019.108584_bb0545","series-title":"Environmental Health Criteria 97","author":"World Health Organization (WHO)","year":"1990"},{"key":"10.1016\/j.cbpc.2019.108584_bb0550","series-title":"WHO Recommended Insecticides for Indoor Residual Spraying against Malaria Vectors","author":"World Health Organization (WHO)","year":"2001"},{"key":"10.1016\/j.cbpc.2019.108584_bb0555","series-title":"Insecticide-Treated Mosquito Net Intervention","author":"World Health Organization W(HO)","year":"2003"},{"key":"10.1016\/j.cbpc.2019.108584_bb0560","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0041-008X(02)00032-7","article-title":"Deltamethrin induces apoptotic cell death in cultured cerebral cortical neurons","volume":"187","author":"Wu","year":"2003","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0565","first-page":"2014","article-title":"Involvement of oxidative stress and inflammation in liver injury caused by perfluorooctanoic acid exposure in mice","author":"Yang","year":"2014","journal-title":"BioMed Res. Internat."},{"key":"10.1016\/j.cbpc.2019.108584_bb0570","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/tox.20225","article-title":"Acute toxicity, behavioral changes, and histopathological effects of deltamethrin on tissues (gills, liver, brain, spleen, kidney, muscle skin) of Nile tilapia (Oreochromis niloticus L) fingerlings","volume":"21","author":"Yildirim","year":"2006","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbpc.2019.108584_bb0575","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/0253-7613.33434","article-title":"Chlorpyrifos-induced oxidative stress and tissue damage in the liver, kidney, brain and fetus in pregnant rats: the protective role of the butanolic extract of Paronychia argentea L","volume":"39","author":"Zama","year":"2007","journal-title":"Indian J. Pharmacol."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153204561930300X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153204561930300X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:23:42Z","timestamp":1761517422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153204561930300X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":115,"alternative-id":["S153204561930300X"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2019.108584","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biochemical and endocrine-disrupting effects in Clarias gariepinus exposed to the synthetic pyrethroids, cypermethrin and deltamethrin","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2019.108584","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108584"}}