{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T03:31:22Z","timestamp":1772767882287,"version":"3.50.1"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"vor","delay-in-days":302,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.cbpc.2020.108953","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:40:27Z","timestamp":1607625627000},"page":"108953","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Hexane extract from SpoSndias mombin L. (Anacardiaceae) prevents behavioral and oxidative status changes on model of Parkinson's disease in zebrafish"],"prefix":"10.1016","volume":"241","author":[{"given":"Glaucia Dal","family":"Santo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Oliveira","family":"de Veras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Rico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacir Dal","family":"Magro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jotele Fontana","family":"Agostini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leucio Duarte","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Felipe Foss\u00e1","family":"Calisto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricieri","family":"Mocelin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vit\u00f3ria","family":"de S\u00e1 Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almir Gon\u00e7alves","family":"Wanderley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2020.108953_bb0005","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/nrneurol.2017.27","article-title":"Cognitive decline in Parkinson disease","volume":"13","author":"Aarsland","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase in vitro","volume":"105","author":"Aebi","year":"1984","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0020","doi-asserted-by":"crossref","DOI":"10.17711\/SM.0185-3325.2015.066","article-title":"Anxiolytic and sedative-like effects of flavonoids from Tilia americana var. mexicana: GABAergic and serotonergic participation","volume":"39","author":"Aguirre-Hern\u00e1ndez","year":"2016","journal-title":"Salud Mental"},{"key":"10.1016\/j.cbpc.2020.108953_bb0025","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3940(01)01636-6","article-title":"Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer\u2019s disease","volume":"302","author":"Aksenov","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cbpc.2020.108953_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.ntt.2019.106822","article-title":"Weekly ethanol exposure alters dopaminergic parameters in zebrafish brain","volume":"75","author":"Alexandre","year":"2019","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0035","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jep.2005.07.019","article-title":"Sedative, antiepileptic and antipsychotic effects of Spondias mombin L. (Anacardiaceae) in mice and rats","volume":"103","author":"Ayoka","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0040","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.neuroscience.2009.09.014","article-title":"Cis-acting elements responsible for dopaminergic neuron-specific expression of zebrafish slc6a3 (dopamine transporter) in vivo are located remote from the transcriptional start site","volume":"164","author":"Bai","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbpc.2020.108953_bb0045","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/9780470110539.ch5","article-title":"Assays for superoxide dismutase","volume":"32","author":"Bannister","year":"1987","journal-title":"Methods Biochem. Anal."},{"key":"10.1016\/j.cbpc.2020.108953_bb0050","first-page":"854015","article-title":"Interactions between CYP3A4 and dietary polyphenols","volume":"2015","author":"Basheer","year":"2016","journal-title":"Oxid. Med. Cell. Long."},{"key":"10.1016\/j.cbpc.2020.108953_bb0055","doi-asserted-by":"crossref","DOI":"10.1186\/s13024-017-0225-5","article-title":"NADPH oxidases in Parkinson's disease: a systematic review","volume":"12","author":"Belarbi","year":"2017","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.cbpc.2020.108953_bb0065","doi-asserted-by":"crossref","first-page":"832","DOI":"10.12968\/bjon.1998.7.14.5636","article-title":"Role of dopamine in schizophrenia and Parkinson's disease","volume":"7","author":"Birtwistle","year":"1998","journal-title":"Br. J. Nurs."},{"key":"10.1016\/j.cbpc.2020.108953_bb0070","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbpc.2020.108953_bb0075","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.ntt.2004.06.014","article-title":"Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease","volume":"26","author":"Bretaud","year":"2004","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0080","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/1731459","article-title":"Antiulcer activity and potential mechanism of action of the leaves of Spondias mombin L","volume":"2018","author":"Brito","year":"2018","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.cbpc.2020.108953_bb0085","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nature09788","article-title":"Caspase signaling controls microglia activation and neurotoxicity","volume":"472","author":"Burguillos","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.cbpc.2020.108953_bb0090","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.bjp.2016.02.002","article-title":"Phytochemical study and anti-inflammatory and antioxidant potential of Spondias mombin leaves","volume":"26","author":"Cabral","year":"2016","journal-title":"Braz. J. Pharmacog."},{"key":"10.1016\/j.cbpc.2020.108953_bb0095","first-page":"2019","article-title":"Bioactive properties of Acacia dealbata flowers extracts","volume":"2","author":"Casas","year":"2019","journal-title":"Waste Biomass Valori."},{"key":"10.1016\/j.cbpc.2020.108953_bb0100","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3390\/md9060952","article-title":"Antioxidant and antiproliferative activities of heterofucans from the seaweed Sargassum filipendula","volume":"9","author":"Costa","year":"2011","journal-title":"Mar. Drugs."},{"key":"10.1016\/j.cbpc.2020.108953_bb0105","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3109\/13880209.2011.627347","article-title":"Chemical composition, antioxidant and antibacterial activities of two Spondias species from Northeastern Brazil","volume":"50","author":"Da Silva","year":"2012","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0115","first-page":"1","article-title":"Algrizea Minor Sobral, Faria & Proen\u00e7a (Myrteae, Myrtaceae): chemical composition, antinociceptive, antimicrobial and antioxidant activity of essential oil","volume":"23","author":"De Veras","year":"2019","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.cbpc.2020.108953_bb0120","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jep.2018.05.037","article-title":"Leaves of Spondias mombin L. a traditional anxiolytic and antidepressant: pharmacological evaluation on zebrafish (Danio rerio)","volume":"224","author":"Dos Santos Sampaio","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0125","first-page":"107","article-title":"Anticholinesterase constituents from the leaves of Spondias mombin L. (Anacardiaceae)","volume":"11","author":"Elufioye","year":"2017","journal-title":"Biologics."},{"key":"10.1016\/j.cbpc.2020.108953_bb0130","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0076-6879(90)86134-H","article-title":"Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal","volume":"186","author":"Esterbauer","year":"1990","journal-title":"Method. Enzymol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0145","doi-asserted-by":"crossref","first-page":"6181","DOI":"10.1523\/JNEUROSCI.23-15-06181.2003","article-title":"Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons","volume":"23","author":"Gao","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cbpc.2020.108953_bb0150","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/mds.26513","article-title":"Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency","volume":"31","author":"Gatt","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.cbpc.2020.108953_bb0155","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.pbb.2011.04.021","article-title":"Effects of anxiolytics in zebrafish: similarities and differences between benzodiazepines, buspirone and ethanol","volume":"99","author":"Gebauer","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.cbpc.2020.108953_bb0160","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.cell.2010.02.016","article-title":"Mechanisms underlying inflammation in neurodegeneration","volume":"140","author":"Glass","year":"2010","journal-title":"Cells"},{"key":"10.1016\/j.cbpc.2020.108953_bb0165","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.phytochem.2004.10.025","article-title":"Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: a mechanism for anti-inflammatory activity","volume":"66","author":"Gon\u00e7alves","year":"2005","journal-title":"Phytochemistry"},{"key":"10.1016\/j.cbpc.2020.108953_bb0170","first-page":"7130","article-title":"Glutathione S-transferases","volume":"249","author":"Habig","year":"1974","journal-title":"The first enzymatic step in mercapturic acid formation. J. Biol. Chem."},{"key":"10.1016\/j.cbpc.2020.108953_bb0175","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.neulet.2011.06.021","article-title":"Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum","volume":"500","author":"Haleagrahara","year":"2011","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cbpc.2020.108953_bb0180","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0925-4773(01)00287-8","article-title":"Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo","volume":"101","author":"Holzschuh","year":"2001","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cbpc.2020.108953_bb0185","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1749-8546-8-19","article-title":"Flavonoids with \u03b1-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea","volume":"18","author":"Hong","year":"2013","journal-title":"Chin. Med."},{"key":"10.1016\/j.cbpc.2020.108953_bb0190","first-page":"20","article-title":"Neuroprotective effects of thymol, a dietary monoterpene against dopaminergic neurodegeneration in rotenone-induced rat model of Parkinson\u2019s disease","volume":"1538","author":"Javed","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2020.108953_bb0195","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.neuroscience.2013.01.032","article-title":"Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats","volume":"236","author":"Karuppagounder","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.cbpc.2020.108953_bb0200","first-page":"137","article-title":"Oxidative stress-related biomarkers in Parkinson\u2019s disease: a systematic review and meta-analysis","volume":"17","author":"Khan","year":"2018","journal-title":"Iran. J. Neurol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12640-011-9295-2","article-title":"Rutin protects dopaminergic neurons from oxidative stress in an animal model of Parkinson's disease","volume":"22","author":"Khan","year":"2012","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.cbpc.2020.108953_bb0210","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.neuro.2018.11.010","article-title":"Soluble epoxide hydrolase inhibitor, APAU, protects dopaminergic neurons against rotenone induced neurotoxicity: implications for Parkinson\u2019s disease","volume":"70","author":"Lakkappaa","year":"2019","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.cbpc.2020.108953_bb0215","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3389\/fnagi.2016.00126","article-title":"Chronic inflammation links cancer and Parkinson\u2019s disease","volume":"8","author":"Li","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.cbpc.2020.108953_bb0220","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1590\/S0100-40422009000500043","article-title":"Compara\u00e7\u00e3o entre m\u00e9todos de quantifica\u00e7\u00e3o em cromatografia gasosa: um experimento para cursos de qu\u00edmica","volume":"32","author":"Ligiero","year":"2009","journal-title":"Quim Nova"},{"key":"10.1016\/j.cbpc.2020.108953_bb0230","doi-asserted-by":"crossref","first-page":"5360","DOI":"10.3390\/molecules19045360","article-title":"Antioxidant and antiproliferative activities of methanolic extract from a neglected agricultural product: corn cobs","volume":"19","author":"Melo-Silveira","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.cbpc.2020.108953_bb0235","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.pbb.2015.08.006","article-title":"N-acetylcysteine prevents stress-induced anxiety behavior in zebrafish","volume":"139","author":"Mocelin","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.cbpc.2020.108953_bb0240","doi-asserted-by":"crossref","first-page":"103","DOI":"10.5607\/en.2015.24.2.103","article-title":"Mitochondrial dysfunction in Parkinson\u2019s disease","volume":"24","author":"Moon","year":"2015","journal-title":"Exp. Neurobiol."},{"key":"10.1016\/j.cbpc.2020.108953_bb9000","series-title":"National Research Council, Guide for the Care and Use of Laboratory Animals","year":"2011"},{"key":"10.1016\/j.cbpc.2020.108953_bb0245","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3923\/pjn.2007.613.615","article-title":"Phytochemical and nutrient evaluation of Spondias mombin leaves","volume":"6","author":"Njoku","year":"2007","journal-title":"Pak. J. Nutr."},{"key":"10.1016\/j.cbpc.2020.108953_bb0250","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/S0891-5849(01)00724-9","article-title":"Reactive oxygen species, antioxidants, and the mammalian thioredoxin system","volume":"31","author":"Nordberg","year":"2001","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpc.2020.108953_bb0255","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3109\/1547691X.2010.531406","article-title":"The leaf extract of Spondias mombin L. displays an anti-inflammatory effect and suppresses inducible formation of tumor necrosis factor-alpha and nitric oxide (NO)","volume":"8","author":"Nworu","year":"2011","journal-title":"J. Immunotoxicol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0260","series-title":"Test No. 203: Fish, Acute Toxicity Test. OECD Guidelines for the Testing of Chemicals, Section 2","author":"OECD","year":"2019"},{"key":"10.1016\/j.cbpc.2020.108953_bb0265","first-page":"73","article-title":"Inhibitory effects of solvent-partitioned fractions of two Nigerian herbs (Spondias mombin Linn. and Mangifera indica L.) on alpha-amylase and alpha-glucosidase","volume":"7","author":"Ojo","year":"2018","journal-title":"Antioxidants (Basel, Switzerland)"},{"issue":"Suppl","key":"10.1016\/j.cbpc.2020.108953_bb0270","first-page":"99","article-title":"Phytochemical and antifungal activities of Uvaria chamae leaves and roots, Spondias mombin leaves and bark and Combretum racemosum leaves","volume":"41","author":"Okwuosa","year":"2012","journal-title":"Afr. J. Med. Sci."},{"key":"10.1016\/j.cbpc.2020.108953_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112265","article-title":"Chemical composition and evaluation of the antinociceptive, antioxidant and antimicrobial effects of essential oil from Hymenaea cangaceira (Pinto, Mansano & Azevedo) native to Brazil: a natural medicine","volume":"247","author":"Oliveira de Veras","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0280","doi-asserted-by":"crossref","first-page":"411","DOI":"10.5604\/12321966.1232774","article-title":"Motor assessment in Parkinson\u2019s disease","volume":"24","author":"Opara","year":"2017","journal-title":"Ann. Agric. Environ. Med."},{"key":"10.1016\/j.cbpc.2020.108953_bb0285","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s00005-007-0039-1","article-title":"Terpenes: substances useful in human healthcare","volume":"55","author":"Paduch","year":"2007","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.cbpc.2020.108953_bb0290","doi-asserted-by":"crossref","DOI":"10.1038\/srep22866","article-title":"NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson\u2019s disease","volume":"6","author":"Pal","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbpc.2020.108953_bb0295","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s11064-014-1259-5","article-title":"Rutin from Dendropanax morbifera Leveille protects human dopaminergic cells against rotenone induced cell injury through inhibiting JNK and p38 MAPK signaling","volume":"39","author":"Park","year":"2014","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.cbpc.2020.108953_bb0300","doi-asserted-by":"crossref","first-page":"3783","DOI":"10.1007\/s12035-016-9944-9","article-title":"The interaction of mitochondrial biogenesis and fission\/fusion mediated by PGC-1alpha regulates rotenone-induced dopaminergic neurotoxicity","volume":"54","author":"Peng","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0305","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s00210-019-01762-8","article-title":"Effects of N-acetylcysteine amide on anxiety and stress behavior in zebrafish","volume":"393","author":"Reis","year":"2020","journal-title":"Naunyn Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0310","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.brainresbull.2009.11.011","article-title":"Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain","volume":"81","author":"Rico","year":"2010","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.cbpc.2020.108953_bb0325","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.parkreldis.2015.09.027","article-title":"Non motor subtypes and Parkinson's disease","volume":"22","author":"Sauerbier","year":"2016","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.cbpc.2020.108953_bb0335","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1590\/S1517-83822007000100030","article-title":"Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chresta scapigera","volume":"38","author":"Schinor","year":"2007","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0340","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cbpc.2020.108953_bb0345","doi-asserted-by":"crossref","DOI":"10.1088\/0957-4484\/27\/37\/375101","article-title":"Synergistic antioxidant action of vitamin E and rutin SNEDDS in ameliorating oxidative stress in a Parkinson's disease model","volume":"27","author":"Sharma","year":"2016","journal-title":"Nanotechnology"},{"key":"10.1016\/j.cbpc.2020.108953_bb0350","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1073\/pnas.0610978104","article-title":"GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism","volume":"104","author":"Smeyne","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cbpc.2020.108953_bb0360","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00702-017-1686-y","article-title":"Epidemiology of Parkinson's disease","volume":"124","author":"Tysnes","year":"2017","journal-title":"J. Neural Transm. (Vienna)"},{"key":"10.1016\/j.cbpc.2020.108953_bb0365","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0370","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0378-8741(96)01500-0","article-title":"Evaluation of the wound-healing activity of selected traditional medicinal plants from Per\u00fa","volume":"55","author":"Villegas","year":"1997","journal-title":"J. Ethnopharmacol."},{"issue":"10","key":"10.1016\/j.cbpc.2020.108953_bb0380","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1002\/cne.23938","article-title":"Expression dynamics of NADPH oxidases during early zebrafish development","volume":"524","author":"Weaver","year":"2015","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.cbpc.2020.108953_bb0385","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.parkreldis.2006.12.014","article-title":"Non-motor dysfunction in Parkinson's disease","volume":"13","author":"Ziemssen","year":"2007","journal-title":"Parkinsonism Relat. D."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045620302532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045620302532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:26:42Z","timestamp":1761517602000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045620302532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":67,"alternative-id":["S1532045620302532"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2020.108953","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hexane extract from SpoSndias mombin L. (Anacardiaceae) prevents behavioral and oxidative status changes on model of Parkinson's disease in zebrafish","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2020.108953","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"108953"}}