{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:00:46Z","timestamp":1785855646372,"version":"3.56.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.cbpc.2023.109675","type":"journal-article","created":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T02:30:31Z","timestamp":1685673031000},"page":"109675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS\/Nrf2 and NF-\u03baB signaling in yellow catfish (Pelteobagrus fulvidraco)"],"prefix":"10.1016","volume":"271","author":[{"given":"Siwen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongke","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2023.109675_bb0005","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.ecoenv.2017.12.001","article-title":"MicroRNAs and their role on fish oxidative stress during xenobiotic environmental exposures","volume":"148","author":"Alberto Burgos-Aceves","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2023.109675_bb0010","doi-asserted-by":"crossref","first-page":"621","DOI":"10.2119\/molmed.2016.00054","article-title":"Superoxide induces neutrophil extracellular trap formation in a TLR-4 and NOX-dependent mechanism","volume":"22","author":"Al-Khafaji","year":"2016","journal-title":"Mol. Med."},{"key":"10.1016\/j.cbpc.2023.109675_bb0015","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.freeradbiomed.2022.05.016","article-title":"Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors","volume":"187","author":"Bayo","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpc.2023.109675_bb0020","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.jnutbio.2011.10.012","article-title":"Inhibition of NF-kappaB nuclear translocation via HO-1 activation underlies alpha-tocopheryl succinate toxicity","volume":"23","author":"Bellezza","year":"2012","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.cbpc.2023.109675_bb0025","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.bbamcr.2018.02.010","article-title":"Nrf2-Keap1 signaling in oxidative and reductive stress","volume":"1865","author":"Bellezza","year":"2018","journal-title":"Biochim. Biophys. Acta, Mol. Cell Res."},{"key":"10.1016\/j.cbpc.2023.109675_bb0030","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.tcb.2015.12.002","article-title":"TNF and ROS crosstalk in inflammation","volume":"26","author":"Blaser","year":"2016","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0035","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.fsi.2022.09.067","article-title":"Cineole regulates Wnt\/\u03b2-catenin pathway through Nrf2\/keap1\/ROS to inhibit bisphenol A-induced apoptosis, autophagy inhibition and immunosuppression of grass carp hepatocytes","volume":"131","author":"Chen","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132491","article-title":"Mechanistic insights into primary biotransformation of diethyl phthalate in earthworm and significant SOD inhibitory effect of esterolytic products","volume":"288","author":"Fan","year":"2022","journal-title":"CHEMOSPHERE"},{"key":"10.1016\/j.cbpc.2023.109675_bb0045","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.taap.2015.01.012","article-title":"Genistein modulates the expression of NF-kappaB and MAPK (p-38 and ERK1\/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats","volume":"283","author":"Ganai","year":"2015","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0050","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1002\/etc.3908","article-title":"Transcriptional and cellular effects of benzotriazole UV stabilizers UV-234 and UV-328 in the freshwater invertebrates Chlamydomonas reinhardtii and Daphnia magna","volume":"36","author":"Giraudo","year":"2017","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.cbpc.2023.109675_bb0055","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.freeradbiomed.2020.07.031","article-title":"NFkappaB promotes oxidative stress-induced necrosis and ischemia\/reperfusion injury by inhibiting Nrf2-ARE pathway","volume":"159","author":"Guo","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cbpc.2023.109675_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2023.113173","article-title":"Genistein carbon dots exhibit antioxidant and anti-inflammatory effects in vitro","volume":"223","author":"Jaiswal","year":"2023","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.cbpc.2023.109675_bb0065","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2131\/jts.36.247","article-title":"Acute toxicity of benzotriazole ultraviolet stabilizers on freshwater crustacean (Daphnia pulex)","volume":"36","author":"Kim","year":"2011","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.cbpc.2023.109675_bb0070","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.chemosphere.2011.06.054","article-title":"Contamination and bioaccumulation of benzotriazole ultraviolet stabilizers in fish from Manila Bay, the Philippines using an ultra-fast liquid chromatography-tandem mass spectrometry","volume":"85","author":"Kim","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2023.109675_bb0075","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.scitotenv.2018.11.298","article-title":"Occurrence of benzotriazole ultraviolet stabilizers (BUVSs) in human breast milk from three Asian countries","volume":"655","author":"Kim","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0080","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s11356-009-0179-4","article-title":"Occurrence of benzotriazoles in the rivers Main, Hengstbach, and Hegbach (Germany)","volume":"16","author":"Kiss","year":"2009","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.cbpc.2023.109675_bb0085","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/tox.22663","article-title":"Transcriptome analysis reveals benzotriazole ultraviolet stabilizers regulate networks related to inflammation in juvenile zebrafish (Danio rerio) brain","volume":"34","author":"Li","year":"2019","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114291","article-title":"Elucidating mechanisms of immunotoxicity by benzotriazole ultraviolet stabilizers in zebrafish (Danio rerio): implication of the AHR-IL17\/IL22 immune pathway","volume":"262","author":"Li","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2023.109675_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.123933","article-title":"Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects","volume":"402","author":"Li","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2023.109675_bb0100","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.fsi.2022.06.029","article-title":"Dietary alpha-lipoic acid alleviates deltamethrin-induced immunosuppression and oxidative stress in northern snakehead (Channa argus) via Nrf2\/NF-kappaB signaling pathway","volume":"127","author":"Li","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0105","article-title":"Benzotriazole UV stabilizer-induced genotoxicity in freshwater benthic clams: a survey on apoptosis, oxidative stress, histopathology and transcriptomics","volume":"857","author":"Li","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0110","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.envpol.2018.10.130","article-title":"Biological effects of the benzotriazole ultraviolet stabilizers UV-234 and UV-320 in early-staged zebrafish (Danio rerio)","volume":"245","author":"Liang","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2023.109675_bb0115","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.scitotenv.2019.03.467","article-title":"Protective effects of genistein on cytochrome P-450 and vitellogenin expression in liver of zebrafish after PCB-126 exposure","volume":"674","author":"Licata","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114081","article-title":"Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation","volume":"244","author":"Liu","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2023.109675_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120877","article-title":"Femtosecond laser attenuates oxidative stress, inflammation, and liver fibrosis in rats: possible role of PPAR gamma and Nrf2\/HO-1 signaling","volume":"307","author":"Mohamed","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.cbpc.2023.109675_bb0130","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/cr.2010.178","article-title":"Crosstalk of reactive oxygen species and NF-kappaB signaling","volume":"21","author":"Morgan","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.cbpc.2023.109675_bb0135","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.biopha.2016.05.023","article-title":"Genistein as antioxidant and antibrowning agents in in vivo and in vitro: a review","volume":"82","author":"Rahman","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.cbpc.2023.109675_bb0140","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1021\/es203376x","article-title":"Concentrations and composition profiles of benzotriazole UV stabilizers in municipal sewage sludge in China","volume":"46","author":"Ruan","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0145","article-title":"Combined negative effects of microplastics and plasticizer DEHP: the increased release of nets delays wound healing in mice","volume":"863","author":"Shi","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0150","doi-asserted-by":"crossref","DOI":"10.1039\/c3em00483j","article-title":"Occurrence and removal of benzotriazole ultraviolet stabilizers in a wastewater treatment plant in China","volume":"16","author":"Song","year":"2014","journal-title":"Environ Sci Process Impacts"},{"key":"10.1016\/j.cbpc.2023.109675_bb0155","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.fsi.2022.05.046","article-title":"Nrf2 pathway in vegetable oil-induced inflammation of large yellow croaker (Larimichthys crocea)","volume":"127","author":"Tan","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117865","article-title":"Berberine improves intestinal barrier function and reduces inflammation, immunosuppression, and oxidative stress by regulating the NF-kappaB\/MAPK signaling pathway in deoxynivalenol-challenged piglets","volume":"289","author":"Tang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2023.109675_bb0165","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.scitotenv.2018.01.042","article-title":"Occurrence of triclocarban and benzotriazole ultraviolet stabilizers in water, sediment, and fish from Indian rivers","volume":"625","author":"Vimalkumar","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101530","article-title":"The aryl hydrocarbon receptor as a target of environmental stressors-implications for pollution mediated stress and inflammatory responses","volume":"34","author":"Vogel","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0175","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.bbrc.2020.04.100","article-title":"Genistein protects against acetaminophen-induced liver toxicity through augmentation of SIRT1 with induction of Nrf2 signalling","volume":"527","author":"Wang","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cbpc.2023.109675_bb0185","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/BST20150014","article-title":"Dissecting molecular cross-talk between Nrf2 and NF-kappaB response pathways","volume":"43","author":"Wardyn","year":"2015","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.cbpc.2023.109675_bb0190","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.fsi.2022.10.022","article-title":"Atrazine exposure induces necroptosis through the P450\/ROS pathway and causes inflammation in the gill of common carp (Cyprinus carpio. L.)","volume":"131","author":"Xu","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737822","article-title":"Evaluation of dietary genistein on the antioxidant capacity, non-specific immune status, and fatty acid composition of common carp (Cyprinus carpio.L)","volume":"550","author":"Yang","year":"2022","journal-title":"AQUACULTURE"},{"key":"10.1016\/j.cbpc.2023.109675_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149390","article-title":"Microplastics pollution and risk assessment in water bodies of two nature reserves in Jilin Province: correlation analysis with the degree of human activity","volume":"799","author":"Yin","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2023.109675_bb0205","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1021\/es2004057","article-title":"Determination of benzotriazole and benzophenone UV filters in sediment and sewage sludge","volume":"45","author":"Zhang","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2023.109675_bb0210","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1007\/s10753-017-0588-3","article-title":"Genistein protects against ox-LDL-induced inflammation through microRNA-155\/SOCS1-mediated repression of NF-kB signaling pathway in HUVECs","volume":"40","author":"Zhang","year":"2017","journal-title":"Inflammation"},{"key":"10.1016\/j.cbpc.2023.109675_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.130811","article-title":"Comparative toxicogenomics of benzotriazole ultraviolet stabilizers at environmental concentrations in Asian clam (Corbicula fluminea): insight into molecular networks and behavior","volume":"447","author":"Zhang","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2023.109675_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120745","article-title":"TBBPA induces inflammation, apoptosis, and necrosis of skeletal muscle in mice through the ROS\/Nrf2\/TNF-alpha signaling pathway","volume":"317","author":"Zhang","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2023.109675_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113121","article-title":"Effect of copper on bioconcentration of benzotriazole ultraviolet stabilizers (BUVSs) in common carp (Cyprinus carpio)","volume":"211","author":"Zhao","year":"2022","journal-title":"Environ. Res."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045623001308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045623001308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T13:25:11Z","timestamp":1736429111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045623001308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":44,"alternative-id":["S1532045623001308"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2023.109675","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS\/Nrf2 and NF-\u03baB signaling in yellow catfish (Pelteobagrus fulvidraco)","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2023.109675","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109675"}}