{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:05:49Z","timestamp":1783742749560,"version":"3.55.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009997","name":"Earmarked Fund for Modern Agro-industry Technology Research System","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009997","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.cbpc.2025.110157","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T17:00:53Z","timestamp":1740416453000},"page":"110157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Chronic fluoride induces neurotoxicity in zebrafish through the gut-brain axis"],"prefix":"10.1016","volume":"292","author":[{"given":"Jianjie","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongju","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinling","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2025.110157_bb0005","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1080\/10408444.2020.1722061","article-title":"Inorganic fluoride and functions of brain","volume":"50","author":"Agalakova","year":"2020","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0010","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.2903\/j.efsa.2013.3332","article-title":"Scientific opinion on dietary reference values for fluoride","volume":"11","author":"Agostoni","year":"2013","journal-title":"EFSA J."},{"key":"10.1016\/j.cbpc.2025.110157_bb0015","doi-asserted-by":"crossref","first-page":"15460","DOI":"10.1038\/s41598-024-65061-w","article-title":"A neurotherapeutic approach with Lacticaseibacillus rhamnosus E9 on gut microbiota and intestinal barrier in MPTP-induced mouse model of Parkinson\u2019s disease","volume":"4","author":"Aktas","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbpc.2025.110157_bb0020","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.neuro.2019.11.008","article-title":"Exploring interactions between xenobiotics, microbiota, and neurotoxicity in zebrafish","volume":"76","author":"Bertotto","year":"2020","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.cbpc.2025.110157_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12876-014-0189-7","article-title":"Intestinal permeability a new target for disease prevention and therapy","volume":"14","author":"Bischoff","year":"2014","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0030","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1601-183X.2006.00243.x","article-title":"D4 dopamine receptor genes of zebrafish and effects of the antipsychotic clozapine on larval swimming behaviour","volume":"6","author":"Boehmler","year":"2007","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.cbpc.2025.110157_bb0035","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.3390\/ijms20071639","article-title":"The olfactory system of zebrafish as a model for the study of neurotoxicity and injury: implications for neuroplasticity and disease","volume":"20","author":"Calvo-Ochoa","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0040","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.fsi.2020.08.039","article-title":"Sesamin attenuates histological alterations, oxidative stress and expressions of immune-related genes in liver of zebrafish (Danio rerio) exposed to fluoride","volume":"106","author":"Cao","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0045","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3390\/ijms21010294","article-title":"L-DOPA in parkinson\u2019s disease: looking at the \u201cfalse\u201d neurotransmitters and their meaning","volume":"21","author":"Chagraoui","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0050","doi-asserted-by":"crossref","first-page":"414","DOI":"10.4103\/ijdr.IJDR_653_16","article-title":"Fluoride in fish flesh, fish bone and regular diet in south-coastal area of Karnataka state of India","volume":"29","author":"Chowdhury","year":"2018","journal-title":"Indian J. Dent. Res."},{"key":"10.1016\/j.cbpc.2025.110157_bb0055","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.chom.2022.09.014","article-title":"Gut colonization by proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses","volume":"30","author":"Cuesta","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.cbpc.2025.110157_bb0060","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ecoenv.2018.11.035","article-title":"Role of fluoride induced epigenetic alterations in the development of skeletal fluorosis","volume":"169","author":"Daiwile","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2025.110157_bb0065","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.4103\/1673-5374.373673","article-title":"Gut-microbiome-brain axis: the crosstalk between the vagus nerve, alpha-synuclein and the brain in Parkinson\u2019s disease","volume":"18","author":"dos Santos","year":"2023","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.cbpc.2025.110157_bb0070","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.721126","article-title":"The relationship between the gut microbiome-immune system-brain axis and major depressive disorder","volume":"12","author":"Foster","year":"2021","journal-title":"Front. Neurol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0075","first-page":"13","article-title":"Impact of fluoride toxicity on fresh water fishes: a mini review","volume":"6","author":"Ghosh","year":"2019","journal-title":"Int. J. Adv. Innov. Res."},{"key":"10.1016\/j.cbpc.2025.110157_bb0080","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S1474-4422(13)70278-3","article-title":"Neurobehavioural effects of developmental toxicity","volume":"13","author":"Grandjean","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130082","article-title":"Effects of thiacloprid exposure on microbiota-gut-liver axis: multiomics mechanistic analysis in Japanese quails","volume":"442","author":"Han","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2025.110157_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126830","article-title":"Micro\/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): insight from brain-gut-microbiota axis","volume":"421","author":"Huang","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2025.110157_bb0095","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/nature13085","article-title":"Nucleotide signalling during inflammation","volume":"509","author":"Idzko","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.cbpc.2025.110157_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envpol.2016.11.045","article-title":"Effects of environmental pollutants on gut microbiota","volume":"222","author":"Jin","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2025.110157_bb0105","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nri.2016.88","article-title":"Immunological aspects of intestinal mucus and mucins","volume":"16","author":"Johansson","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0110","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.3390\/ijms21072361","article-title":"Fluoride affects dopamine metabolism and causes changes in the expression of dopamine receptors (D1R and D2R) in chosen brain structures of morphine-dependent rats","volume":"21","author":"Kupnicka","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127105","article-title":"Fluoride impairs ovary development by affecting oogenesis and inducing oxidative stress and apoptosis in female zebrafish (danio rerio)","volume":"256","author":"Li","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2025.110157_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105293","article-title":"Early-life exposure to the organophosphorus flame-retardant tris (1, 3-dichloro-2-propyl) phosphate induces delayed neurotoxicity associated with DNA methylation in adult zebrafish","volume":"134","author":"Li","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.cbpc.2025.110157_bb0125","doi-asserted-by":"crossref","first-page":"11894","DOI":"10.1021\/acs.est.1c03457","article-title":"Dietary seleno-l-methionine causes alterations in neurotransmitters, ultrastructure of the brain, and behaviors in zebrafish (Danio rerio)","volume":"55","author":"Li","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165974","article-title":"Flunitrazepam induces neurotoxicity in zebrafish through microbiota-gut-brain axis","volume":"901","author":"Lin","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.cbpc.2025.110157_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124923","article-title":"Towards screening the neurotoxicity of chemicals through guts after exposure to methylmercury or inorganic mercury in rats: a combined study using gut microbiome, metabolomics and metallomics","volume":"409","author":"Lin","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2025.110157_bb0140","doi-asserted-by":"crossref","first-page":"16515","DOI":"10.1021\/acs.est.1c04533","article-title":"Dietary Seleno-l-methionine alters the microbial communities and causes damage in the gastrointestinal tract of Japanese Medaka Oryzias latipes","volume":"55","author":"Liu","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0145","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.chemosphere.2019.06.080","article-title":"Intestinal barrier damage involved in intestinal microflora changes in fluoride-induced mice","volume":"234","author":"Liu","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2025.110157_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.129109","article-title":"Involvement of dopamine signaling pathway in neurodevelopmental toxicity induced by isoniazid in zebrafish","volume":"265","author":"Liu","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2025.110157_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114832","article-title":"Dietary administration of probiotic Lactobacillus rhamnosus modulates the neurological toxicities of perfluorobutanesulfonate in zebrafish","volume":"265","author":"Liu","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2025.110157_bb0160","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.toxlet.2009.11.002","article-title":"Alterations of nAChRs and ERK1\/2 in the brains of rats with chronic fluorosis and their connections with the decreased capacity of learning and memory","volume":"192","author":"Liu","year":"2010","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.cbpc.2025.110157_bb0165","article-title":"Sex-specific effects of fluoride and lead on thyroid endocrine function in zebrafish (Danio rerio)","volume":"367","author":"Lu","year":"2002","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.cbpc.2025.110157_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2022.114115","article-title":"BDNF loss affects activity, sociability, and anxiety-like behaviour in zebrafish","volume":"436","author":"Lucon-Xiccato","year":"2023","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cbpc.2025.110157_bb0175","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.170122","article-title":"ZC4H2 stabilizes Smads to enhance BMP signaling, which is involved in neural development in Xenopus","volume":"7","author":"Ma","year":"2017","journal-title":"Open Biol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2021.100294","article-title":"Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota","volume":"14","author":"Ma","year":"2021","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.cbpc.2025.110157_bb0185","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1093\/hmg\/ddv208","article-title":"ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons","volume":"24","author":"May","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cbpc.2025.110157_bb0190","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1749-6632.1998.tb08230.x","article-title":"The impact of gender and estrogen on striatal dopaminergic neurotoxicity","volume":"844","author":"Miller","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0195","unstructured":"Ministry of Agriculture. Water Quality of Fresh Water Aquaculture for Pollution Free Food. NY 5051\u20132001."},{"key":"10.1016\/j.cbpc.2025.110157_bb0200","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1002\/jcp.25518","article-title":"Neurotransmitters: the critical modulators regulating gut-brain axis","volume":"232","author":"Mittal","year":"2017","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105420","article-title":"Alteration of gut microbiota composition and function of Indian major carp, rohu (Labeo rohita) infected with Argulus siamensis","volume":"164","author":"Mondal","year":"2022","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.cbpc.2025.110157_bb0210","doi-asserted-by":"crossref","first-page":"364","DOI":"10.3109\/15376516.2015.1025348","article-title":"Sodium fluoride generates ROS and alters transcription of genes for xenobiotic metabolizing enzymes in adult zebrafish (Danio rerio) liver: expression pattern of Nrf2\/Keap1 (INrf2)","volume":"25","author":"Mukhopadhyay","year":"2015","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.cbpc.2025.110157_bb0215","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.envpol.2018.02.033","article-title":"Dopaminergic dysregulation and impaired associative learning behavior in zebrafish during chronic dietary exposure to selenium[J]","volume":"237","author":"Naderi","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.cbpc.2025.110157_bb0220","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.chemosphere.2017.12.027","article-title":"Effects of fluoride on synapse morphology and myelin damage in mouse hippocampus","volume":"194","author":"Niu","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2025.110157_bb0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-56132-4","article-title":"Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome","volume":"9","author":"Nozu","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbpc.2025.110157_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.ntt.2020.106902","article-title":"Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function","volume":"81","author":"Oliveri","year":"2020","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0235","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S1684-1182(10)60053-9","article-title":"Plesiomonas shigelloides sepsis and meningoencephalitis in a surviving neonate","volume":"43","author":"Ozdemir","year":"2010","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"10.1016\/j.cbpc.2025.110157_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129443","article-title":"Mice brain metabolomics after the exposure to a \u201cchemical cocktail\u201d and selenium supplementation through the gut-brain axis","volume":"438","author":"Parra-Mart\u00ednez","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2025.110157_bb0245","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s12640-009-9139-5","article-title":"Memory impairment induced by sodium fluoride is associated with changes in brain monoamine levels","volume":"19","author":"Pereira","year":"2011","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.cbpc.2025.110157_bb0250","first-page":"155","article-title":"Determination of fluoride content in drinking water and tea infusions using fluoride ion selective electrode","volume":"52","author":"Rajkovic","year":"2007","journal-title":"J. Agric. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0255","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.3390\/ijms22062973","article-title":"Tryptophan metabolism and gut-brain homeostasis","volume":"22","author":"Roth","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0260","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.neuron.2004.12.056","article-title":"An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission","volume":"45","author":"Sara","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.cbpc.2025.110157_bb0265","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.fct.2014.01.020","article-title":"Ameliorative effects of oleanolic acid on fluoride induced metabolic and oxidative dysfunctions in rat brain: experimental and biochemical studies","volume":"66","author":"Sarkar","year":"2014","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0270","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/s41586-018-0634-9","article-title":"A gut microbial factor modulates locomotor behaviour in Drosophila","volume":"563","author":"Schretter","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.cbpc.2025.110157_bb0275","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/appe.2000.0370","article-title":"Post-ingestive positive controls of ingestive behavior","volume":"36","author":"Sclafani","year":"2001","journal-title":"Appetite"},{"key":"10.1016\/j.cbpc.2025.110157_bb0280","doi-asserted-by":"crossref","first-page":"13916","DOI":"10.1021\/acs.jafc.0c05834","article-title":"Exposure to perfluorooctanoic acid induces cognitive deficits via altering gut microbiota composition, impairing intestinal barrier integrity, and causing inflammation in gut and brain","volume":"68","author":"Shi","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cbpc.2025.110157_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112108","article-title":"Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice","volume":"215","author":"Xin","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2025.110157_bb0290","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.chemosphere.2018.10.147","article-title":"Effects of hexavalent chromium on intestinal histology and microbiota in Bufo gargarizans tadpoles","volume":"216","author":"Yao","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2025.110157_bb0295","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.fsi.2018.11.007","article-title":"Dietary lactobacillus plantarum ST-III alleviates the toxic effects of triclosan on zebrafish (Danio rerio) via gut microbiota modulation","volume":"84","author":"Zang","year":"2019","journal-title":"Fish & Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0300","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.fsi.2022.07.006","article-title":"Interactive effects of fluoride and seleno-l-methionine at environmental related concentrations on zebrafish (Danio rerio) liver via the gut-liver axis","volume":"127","author":"Zhang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.cbpc.2025.110157_bb0305","first-page":"253","article-title":"Mechanism of learning and memory impairment in rats exposed to arsenic and\/or fluoride based on microbiome and metabolome","volume":"36","author":"Zhang","year":"2023","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.cbpc.2025.110157_bb0310","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00213-012-2896-5","article-title":"Cariprazine, a dopamine D3-receptor-preferring partial agonist, blocks phencyclidine-induced impairments of working memory, attention set-shifting, and recognition memory in the mouse","volume":"226","author":"Zimnisky","year":"2013","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.cbpc.2025.110157_bb0315","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/pr.2016.91","article-title":"Postnatal development of the dopaminergic signaling involved in the modulation of intestinal motility in mice","volume":"80","author":"Zizzo","year":"2016","journal-title":"Pediatr. Res."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045625000389?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045625000389?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T07:20:46Z","timestamp":1741504846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045625000389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":63,"alternative-id":["S1532045625000389"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2025.110157","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic fluoride induces neurotoxicity in zebrafish through the gut-brain axis","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2025.110157","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110157"}}