{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T21:03:13Z","timestamp":1762549393838,"version":"build-2065373602"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["301809\/2022-4","173842\/2024-0"],"award-info":[{"award-number":["301809\/2022-4","173842\/2024-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003545","name":"Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o","doi-asserted-by":"publisher","award":["405706\/2022-7"],"award-info":[{"award-number":["405706\/2022-7"]}],"id":[{"id":"10.13039\/501100003545","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.cbpc.2025.110299","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T06:52:32Z","timestamp":1753253552000},"page":"110299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A mechanistic investigation of the effects of lactic acidosis on myocardial contractility in the Neotropical fast-swimming freshwater fish Brycon amazonicus"],"prefix":"10.1016","volume":"297","author":[{"given":"Andr\u00e9 Guelli","family":"Lopes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscila Rodrigues","family":"de Siqueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Tadeu","family":"Rantin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia","family":"Kalinin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Amaral","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cbpc.2025.110299_bb0005","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1590\/S0103-90162010000300001","article-title":"Optimization of sustaining swimming speed of matrinx\u00e3 Brycon amazonicus: performance and adaptive aspects","volume":"67","author":"Arbel\u00e1ez-Rojas","year":"2010","journal-title":"Sci. Agric."},{"key":"10.1016\/j.cbpc.2025.110299_bb0010","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1161\/01.RES.55.3.382","article-title":"Inhibition of the activation and troponin calcium binding of dog cardiac myofibrils by acidic pH","volume":"55","author":"Blanchard","year":"1984","journal-title":"Circ. Res."},{"key":"10.1016\/j.cbpc.2025.110299_bb0015","doi-asserted-by":"crossref","first-page":"jeb242503","DOI":"10.1242\/jeb.242503","article-title":"Physiological and behavioural strategies of aquatic animals living in fluctuating environments","volume":"225","author":"Blewett","year":"2022","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-201X.2002.01001.x","article-title":"Lithium and KB-R7943 effects on mechanics and energetics of rat heart muscle","volume":"176","author":"Bonazzola","year":"2002","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.cbpc.2025.110299_bb0025","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S0022-3565(24)37437-3","article-title":"Effects of angiotensin II on intracellular calcium and contracture in metabolically inhibited cardiomyocytes","volume":"285","author":"Boston","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.cbpc.2025.110299_bb0030","series-title":"Cardio-Respiratory Control in Vertebrates","first-page":"43","article-title":"Patterns of acid\u2013base regulation during exposure to hypercarbia in fishes","author":"Brauner","year":"2009"},{"key":"10.1016\/j.cbpc.2025.110299_bb0035","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1242\/jeb.01144","article-title":"Limited extracellular but complete intracellular acid-base regulation during short-term environmental hypercapnia in the armoured catfish, Liposarcus pardalis","volume":"207","author":"Brauner","year":"2004","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0040","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.cbpc.2025.110299_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2016.00562","article-title":"Myofilament calcium sensitivity: role in regulation of in vivo cardiac contraction and relaxation","volume":"7","author":"Chung","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0050","doi-asserted-by":"crossref","first-page":"H843","DOI":"10.1152\/ajpheart.1990.259.3.H843","article-title":"Recovery of contractility and pHi during respiratory acidosis in ferret hearts: role of Na(+)-H+ exchange","volume":"259","author":"Cingolani","year":"1990","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0055","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cmet.2016.07.003","article-title":"Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation","volume":"24","author":"Corbet","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.cbpc.2025.110299_bb0060","first-page":"R1493","article-title":"The calcium stored in the sarcoplasmic reticulum acts as a safety mechanism in rainbow trout heart","volume":"307","author":"Cros","year":"2014","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.cbpc.2025.110299_bb0065","first-page":"1290","article-title":"High capacity for extracellular acid-base regulation in the air-breathing fish Pangasianodon hypophthalmus","volume":"218","author":"Damsgaard","year":"2015","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0070","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1152\/physrev.1994.74.1.221","article-title":"Energy metabolism and contractility in ectothermic vertebrate hearts: hypoxia, acidosis, and low temperature","volume":"74","author":"Driedzic","year":"1994","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cbpc.2025.110299_bb0075","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1113\/jphysiol.1978.sp012231","article-title":"Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiac and skeletal muscles","volume":"276","author":"Fabiato","year":"1978","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0080","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1590\/S1679-62252013000200013","article-title":"Intermittent sustained swimming in \u201cmatrinx\u00e3\u201d Brycon amazonicus (Bryconidae: Bryconinae): hematological and metabolic responses","volume":"11","author":"Fabrizzi","year":"2013","journal-title":"Neotropical Ichthyology"},{"key":"10.1016\/j.cbpc.2025.110299_bb0085","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1242\/jeb.125.1.347","article-title":"Myocardial intracellular pH in a perfused rainbow trout heart during extracellular acidosis in the presence and absence of adrenaline","volume":"125","author":"Farrell","year":"1986","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0090","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1242\/jeb.107.1.415","article-title":"Cardiac performance in the in situ perfused fish heart during extracellular acidosis: interactive effects of adrenaline","volume":"107","author":"Farrell","year":"1983","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0095","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1590\/S0044-59672010000400009","article-title":"Velocidade cr\u00edtica de nata\u00e7\u00e3o (Ucrit) de matrinx\u00e3 (Brycon amazonicus) ap\u00f3s exposi\u00e7\u00e3o \u00e0 hipoxia","volume":"40","author":"Ferreira","year":"2010","journal-title":"Acta Amaz"},{"key":"10.1016\/j.cbpc.2025.110299_bb0100","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.5719","article-title":"Could resistance to lactate accumulation contribute to the better swimming performance of Brycon amazonicus when compared to Colossoma macropomum?","volume":"6","author":"Ferreira","year":"2018","journal-title":"PeerJ"},{"key":"10.1016\/j.cbpc.2025.110299_bb0105","series-title":"New advances and contributions to fish biology. InTech","article-title":"Functional and structural differences in atria versus ventricles in teleost hearts","author":"Genge","year":"2012"},{"key":"10.1016\/j.cbpc.2025.110299_bb0110","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00688803","article-title":"Effects of different types of acidosis and Ca2+ on cardiac contractility in the flounder (Pleuronectes flesus)","volume":"131","author":"Gesser","year":"1979","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0115","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/0300-9629(83)90458-9","article-title":"Acidosis and cardiac muscle contractility: comparative aspects","volume":"76","author":"Gesser","year":"1983","journal-title":"Comp. Biochem. Physiol. A Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0125","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1242\/jeb.022764","article-title":"Intrinsic mechanical properties of the perfused armored catfish heart with special reference to the effects of hypercapnic acidosis on maximum cardiac performance","volume":"212","author":"Hanson","year":"2009","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0130","doi-asserted-by":"crossref","first-page":"C348","DOI":"10.1152\/ajpcell.1992.262.2.C348","article-title":"Contraction and intracellular Ca2+, Na+, and H+ during acidosis in rat ventricular myocytes","volume":"262","author":"Harrison","year":"1992","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0140","article-title":"Dual effect of polyaromatic hydrocarbons on sarco(endo)plasmic reticulum calcium ATPase (SERCA) activity of a teleost fish (Oncorhynchus mykiss)","volume":"276","author":"Haverinen","year":"2024","journal-title":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"},{"key":"10.1016\/j.cbpc.2025.110299_bb0145","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1161\/01.RES.0000055904.21974.BE","article-title":"Sarcoplasmic reticulum Ca2+ release is not a dominating factor in sinoatrial node pacemaker activity","volume":"92","author":"Honjo","year":"2003","journal-title":"Circ. Res."},{"key":"10.1016\/j.cbpc.2025.110299_bb0150","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1590\/S0044-59672009000200025","article-title":"Respostas fisiol\u00f3gicas de estresse no matrinx\u00e3 (Brycon amazonicus) ap\u00f3s exerc\u00edcio f\u00edsico intenso durante a captura","volume":"39","author":"Hoshiba","year":"2009","journal-title":"Acta Amazon."},{"key":"10.1016\/j.cbpc.2025.110299_bb0155","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s004240000470","article-title":"Characterization of the relationship between Na+\/Ca2+ exchange rate and cytosolic calcium in trout cardiac myocytes","volume":"441","author":"Hove-Madsen","year":"2001","journal-title":"Pfl\u00fcgers Archiv European Journal of Physiology"},{"key":"10.1016\/j.cbpc.2025.110299_bb0160","first-page":"R1856","article-title":"Na(+)\/ca(2+)-exchange activity regulates contraction and SR ca(2+) content in rainbow trout atrial myocytes","volume":"279","author":"Hove-Madsen","year":"2000","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.cbpc.2025.110299_bb0165","doi-asserted-by":"crossref","first-page":"H977","DOI":"10.1152\/ajpheart.1998.275.3.H977","article-title":"Effect of acidosis on Ca2+ uptake and release by sarcoplasmic reticulum of intact rat ventricular myocytes","volume":"275","author":"Hulme","year":"1998","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0170","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s004240050423","article-title":"Acidosis alters the phosphorylation of Ser 16 and Thr 17 of phospholamban in rat cardiac muscle","volume":"434","author":"Hulme","year":"1997","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.cbpc.2025.110299_bb0175","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1113\/JP282168","article-title":"Interaction of background Ca2+ influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca2+ waves in sheep heart","volume":"600","author":"Hutchings","year":"2022","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0180","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1086\/682701","article-title":"Anoxia and acidosis tolerance of the heart in an air-breathing fish (Pangasianodon hypophthalmus)","volume":"88","author":"Joyce","year":"2015","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.cbpc.2025.110299_bb0185","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1113\/jphysiol.2003.045872","article-title":"Acidosis inhibits oxidative phosphorylation in contracting human skeletal muscle in vivo","volume":"553","author":"Jubrias","year":"2003","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0190","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s00360-001-0237-9","article-title":"Oxygen consumption and force development in turtle and trout cardiac muscle during acidosis and high extracellular potassium","volume":"172","author":"Kalinin","year":"2002","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0195","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1095-6433(00)00202-6","article-title":"Limits to exhaustive exercise in fish","volume":"126","author":"Kieffer","year":"2000","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0200","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1242\/jeb.194.1.299","article-title":"Effects of environmental temperature on the metabolic and acid\u2013base responses of rainbow trout to exhaustive exercise","volume":"194","author":"Kieffer","year":"1994","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0205","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s10974-020-09593-4","article-title":"Acidosis modifies effects of phosphorylated tropomyosin on the actin-myosin interaction in the myocardium","volume":"42","author":"Kopylova","year":"2021","journal-title":"J. Muscle Res. Cell Motil."},{"key":"10.1016\/j.cbpc.2025.110299_bb2205","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1242\/jeb.198.4.1035","article-title":"The effect of cycle frequency on the power output of rat papillary muscles in vitro","volume":"198","author":"Layland","year":"1995","journal-title":"J. Exp. Biol."},{"issue":"1","key":"10.1016\/j.cbpc.2025.110299_bb0215","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00360-020-01324-y","article-title":"Differential effects of bicarbonate on severe hypoxia- and hypercapnia-induced cardiac malfunctions in diverse fish species","volume":"191","author":"Lo","year":"2021","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0220","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1113\/JP282126","article-title":"The HVCN1 voltage-gated proton channel contributes to pH regulation in canine ventricular myocytes","volume":"600","author":"Ma","year":"2022","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0225","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S1095-6433(02)00315-X","article-title":"Mitochondrial KATP channels and sarcoplasmic reticulum influence cardiac force development under anoxia in the Amazonian armored catfish Liposarcus pardalis","volume":"134","author":"MacCormack","year":"2003","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.56946\/jzs.v1i2.198","article-title":"Effect of temperature, pH, salinity and dissolved oxygen on fishes","volume":"1","author":"Mariu","year":"2023","journal-title":"Journal of Zoology and Systematics"},{"issue":"5","key":"10.1016\/j.cbpc.2025.110299_bb0235","first-page":"5","article-title":"The role of CaMKII regulation of phospholamban activity in heart disease","volume":"27","author":"Mattiazzi","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0240","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.cardiores.2006.12.002","article-title":"Ca2+ \/calmodulin-dependent protein kinase: a key component in the contractile recovery from acidosis","volume":"73","author":"Mattiazzi","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cbpc.2025.110299_bb0245","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1242\/jeb.123.1.123","article-title":"Tissue intracellular acid-base status and the fate of lactate after exhaustive exercise in the rainbow trout","volume":"123","author":"Milligan","year":"1986","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxicon.2015.11.012","article-title":"Alternagin-C (ALT-C), a disintegrin-like protein from Rhinocerophis alternatus snake venom promotes positive inotropism and chronotropism in fish heart","volume":"110","author":"Monteiro","year":"2016","journal-title":"Toxicon"},{"key":"10.1016\/j.cbpc.2025.110299_bb0255","first-page":"26","article-title":"Impact of waterborne and trophic mercury exposures on cardiac function of two ecologically distinct Neotropical freshwater fish Brycon amazonicus and Hoplias malabaricus","volume":"201","author":"Monteiro","year":"2017","journal-title":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"},{"key":"10.1016\/j.cbpc.2025.110299_bb0260","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1007\/s10695-021-01023-7","article-title":"Cardiac contractility of the African sharptooth catfish, Clarias gariepinus: role of extracellular Ca2+, sarcoplasmic reticulum, and \u03b2-adrenergic stimulation","volume":"47","author":"Monteiro","year":"2021","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2025.110299_bb0265","first-page":"C107","article-title":"Effects of acidosis on phosphorylation of phospholamban and troponin I in rat cardiac muscle","volume":"270","author":"Mundina-Weilenmann","year":"1996","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.cbpc.2025.110299_bb0270","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cardiores.2004.12.028","article-title":"Role of phosphorylation of Thr residue of phospholamban in mechanical recovery during hypercapnic acidosis","volume":"66","author":"Mundi\u00f1a-Weilenmann","year":"2005","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cbpc.2025.110299_bb0275","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1590\/1519-6984.13914","article-title":"Embryonic and larval development of Brycon amazonicus (SPIX & AGASSIZ, 1829)","volume":"76","author":"Nakauth","year":"2016","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0280","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.yjmcc.2013.02.014","article-title":"While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKII\u03b4-KO mice","volume":"59","author":"Neef","year":"2013","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0285","doi-asserted-by":"crossref","first-page":"H193","DOI":"10.1152\/ajpheart.00026.2001","article-title":"CaMKII-dependent reactivation of SR Ca2+ uptake and contractile recovery during intracellular acidosis","volume":"283","author":"Nomura","year":"2002","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0290","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1113\/jphysiol.1987.sp016462","article-title":"The role of the sarcoplasmic reticulum in the response of ferret and rat heart muscle to acidosis","volume":"384","author":"Orchard","year":"1987","journal-title":"J. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0295","first-page":"C967","article-title":"Effects of changes of pH on the contractile function of cardiac muscle","volume":"258","author":"Orchard","year":"1990","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.cbpc.2025.110299_bb0300","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.yjmcc.2013.06.001","article-title":"Na\/ca exchange and contraction of the heart","volume":"61","author":"Ottolia","year":"2013","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0305","first-page":"107","article-title":"Role of Na+ \/H+ exchange in the recovery of contractility during hypercapnia in cat papillary muscles","volume":"101","author":"P\u00e9rez","year":"1993","journal-title":"Arch. Int. Physiol. Biochim. Biophys."},{"key":"10.1016\/j.cbpc.2025.110299_bb0310","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S1095-6433(01)00462-7","article-title":"Critical swimming speed: its ecological relevance","volume":"131","author":"Plaut","year":"2001","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0315","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1242\/jeb.160.1.113","article-title":"Effects of environmental factors on exercise in fish","volume":"160","author":"Randall","year":"1991","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0320","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1006\/jmcc.2001.1521","article-title":"Effects of Na+\/Ca2+-exchanger overexpression on excitation\u2013contraction coupling in adult rabbit ventricular myocytes","volume":"34","author":"Ranu","year":"2002","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0325","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.cbpa.2017.09.016","article-title":"Effects of exercise training on excitation-contraction coupling, calcium dynamics and protein expression in the heart of the Neotropical fish Brycon amazonicus","volume":"214","author":"Rissoli","year":"2017","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0335","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1007\/s00360-007-0166-3","article-title":"Importance of the sarcoplasmic reticulum and adrenergic stimulation on the cardiac contractility of the neotropical teleost Synbranchus marmoratus under different thermal conditions","volume":"177","author":"Rocha","year":"2007","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0340","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1242\/jeb.02087","article-title":"Contractile recovery from acidosis in toad ventricle is independent of intracellular pH and relies upon Ca2+ influx","volume":"209","author":"Salas","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0345","doi-asserted-by":"crossref","first-page":"H613","DOI":"10.1152\/ajpheart.01219.2004","article-title":"Effects of caffeine, verapamil, lithium, and KB-R7943 on mechanics and energetics of rat myocardial bigeminies","volume":"290","author":"Savio-Galimberti","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0350","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10695-009-9305-y","article-title":"Effect of temperature on muscle lactate metabolic recovery in sea bass (Dicentrarchus labrax, L.) juveniles exposed to exhaustive exercise","volume":"36","author":"Sfakianakis","year":"2010","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2025.110299_bb0355","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00360-017-1065-x","article-title":"White sturgeon (Acipenser transmontanus) acid\u2013base regulation differs in response to different types of acidoses","volume":"187","author":"Shartau","year":"2017","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0360","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S1095-6433(00)00161-6","article-title":"The effect of ryanodine on isometric tension development in isolated ventricular trabeculae from Pacific mackerel (Scomber japonicus)","volume":"125","author":"Shiels","year":"2000","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0365","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1242\/jeb.205.23.3631","article-title":"Temperature dependence of cardiac sarcoplasmic reticulum function in rainbow trout myocytes","volume":"205","author":"Shiels","year":"2002","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0370","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1242\/jeb.02321","article-title":"Sarcolemmal ion currents and sarcoplasmic reticulum Ca2+ content in ventricular myocytes from the cold stenothermic fish, the burbot (Lota lota)","volume":"209","author":"Shiels","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0375","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1086\/644759","article-title":"Hypercapnic acidosis reduces contractile function in the ventricle of the armored catfish, Pterygoplichthys pardalis","volume":"83","author":"Shiels","year":"2010","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.cbpc.2025.110299_bb0380","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1124\/jpet.115.227173","article-title":"Inhibition of plasma membrane Na\/ca-exchanger by KB-R7943 or lithium reveals its role in ca-dependent n-methyl-d-aspartate receptor inactivation","volume":"355","author":"Sibarov","year":"2015","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.cbpc.2025.110299_bb0385","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1023\/A:1007154412805","article-title":"Na+\/K+-ATPase inhibition during cardiac myocyte swelling: involvement of intracellular pH and Ca2+","volume":"210","author":"Souza","year":"2000","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.cbpc.2025.110299_bb2385","series-title":"Selecta genera et species piscium quos in itinere per Brasiliam annos MDCCCXVII-MDCCCXX jussu et auspiciis Maximiliani Josephi I.... colleget et pingendso curavit Dr. J.B. de Spix... Monachii","first-page":"82","author":"Spix","year":"1829"},{"key":"10.1016\/j.cbpc.2025.110299_bb0390","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF03186004","article-title":"pH regulation during long-term swimming in the mullet, Rhinomugil corsula (Hamilton)","volume":"90","author":"Sukumaran","year":"1981","journal-title":"Proc. Anim. Sci."},{"key":"10.1016\/j.cbpc.2025.110299_bb0395","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0034-5687(87)90079-X","article-title":"Effects of graded exercise on blood gas tensions and acid-base characteristics of rainbow trout","volume":"68","author":"Thomas","year":"1987","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0400","doi-asserted-by":"crossref","first-page":"21830","DOI":"10.1038\/s41598-022-25574-8","article-title":"The reverse mode of the Na+\/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells","volume":"12","author":"T\u00f3th","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cbpc.2025.110299_bb0405","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/jez.2367","article-title":"Evolutionary links between intra- and extracellular acid\u2013base regulation in fish and other aquatic animals","volume":"333","author":"Tresguerres","year":"2020","journal-title":"Journal of Experimental Zoology, Part A: Ecological and Integrative Physiology"},{"key":"10.1016\/j.cbpc.2025.110299_bb0410","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s10695-011-9501-4","article-title":"An opinion paper: emphasis on white muscle development and growth to improve farmed fish flesh quality","volume":"37","author":"Videler","year":"2011","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.cbpc.2025.110299_bb0415","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.cardiores.2006.12.003","article-title":"CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury","volume":"73","author":"Vila-Petroff","year":"2007","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cbpc.2025.110299_bb0420","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S1095-6433(02)00051-X","article-title":"Plasticity of excitation\u2013contraction coupling in fish cardiac myocytes","volume":"132","author":"Vornanen","year":"2002","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0425","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.yjmcc.2013.02.007","article-title":"Regulation of the cardiac Na+\/H+ exchanger in health and disease","volume":"61","author":"Wakabayashi","year":"2013","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0430","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1242\/jeb.195.1.227","article-title":"Integrated responses to exhaustive exercise and recovery in rainbow trout white muscle: acid\u2013base, phosphogen, carbohydrate, lipid, ammonia, fluid volume and electrolyte metabolism","volume":"195","author":"Wang","year":"1994","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0435","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1111\/j.1095-8649.1994.tb00950.x","article-title":"The analysis of metabolites in rainbow trout white muscle: a comparison of different sampling and processing methods","volume":"45","author":"Wang","year":"1994","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.cbpc.2025.110299_bb0440","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/BF00684445","article-title":"The effects of different types of acidosis and extracellular calcium on the mechanical activity of turtle atria","volume":"154","author":"Yee","year":"1984","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.cbpc.2025.110299_bb0445","doi-asserted-by":"crossref","first-page":"663","DOI":"10.3892\/ijmm.2020.4631","article-title":"TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening","volume":"46","author":"Zhang","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.cbpc.2025.110299_bb0450","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41420-021-00786-5","article-title":"TRAP1 inhibits MIC60 ubiquitination to mitigate the injury of cardiomyocytes and protect mitochondria in extracellular acidosis","volume":"7","author":"Zhang","year":"2021","journal-title":"Cell Death Discovery"}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045625001802?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045625001802?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T20:59:01Z","timestamp":1762549141000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045625001802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":88,"alternative-id":["S1532045625001802"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2025.110299","relation":{},"ISSN":["1532-0456"],"issn-type":[{"type":"print","value":"1532-0456"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A mechanistic investigation of the effects of lactic acidosis on myocardial contractility in the Neotropical fast-swimming freshwater fish Brycon amazonicus","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2025.110299","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110299"}}