{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T13:09:47Z","timestamp":1771420187002,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013254","name":"National College Students Innovation and Entrepreneurship Training Program","doi-asserted-by":"publisher","award":["202210418011"],"award-info":[{"award-number":["202210418011"]}],"id":[{"id":"10.13039\/501100013254","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011989","name":"Gannan Normal University","doi-asserted-by":"publisher","award":["YCXJ25- A19"],"award-info":[{"award-number":["YCXJ25- A19"]}],"id":[{"id":"10.13039\/501100011989","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009102","name":"Education Department of Jiangxi Province","doi-asserted-by":"publisher","award":["GJJ2501103"],"award-info":[{"award-number":["GJJ2501103"]}],"id":[{"id":"10.13039\/501100009102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.cbpc.2026.110476","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:17:32Z","timestamp":1770016652000},"page":"110476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Rare earth element erbium induces hepatotoxicity in zebrafish"],"prefix":"10.1016","volume":"303","author":[{"given":"Xinhao","family":"Ye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mijia","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimei","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyuan","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6426","key":"10.1016\/j.cbpc.2026.110476_bb0005","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1126\/science.aau7628","article-title":"Rare earth elements: Mendeleev's bane, modern marvels","volume":"363","author":"Cheisson","year":"2019","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.cbpc.2026.110476_bb0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18051098","article-title":"How ketamine affects livers of pregnant mice and developing mice?","volume":"18","author":"Cheung","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2026.110476_bb0015","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.scitotenv.2018.04.235","article-title":"Sources, behaviour, and environmental and human health risks of high-technology rare earth elements as emerging contaminants","volume":"636","author":"Gwenzi","year":"2018","journal-title":"Sci. Total Environ."},{"issue":"25","key":"10.1016\/j.cbpc.2026.110476_bb0020","doi-asserted-by":"crossref","first-page":"37125","DOI":"10.1007\/s11356-024-33633-y","article-title":"Toxicity of two heavy rare earth elements to freshwater mussels Dreissena polymorpha","volume":"31","author":"Hanana","year":"2024","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.cbpc.2026.110476_bb0025","doi-asserted-by":"crossref","first-page":"142951","DOI":"10.1016\/j.chemosphere.2024.142951","article-title":"A systematic review and meta-analysis on the root effects and toxic mechanisms of rare earth elements","volume":"363","author":"He","year":"2024","journal-title":"Chemosphere"},{"issue":"PT A","key":"10.1016\/j.cbpc.2026.110476_bb0030","article-title":"Exposure to oxadiazon-butachlor causes cardiac toxicity in zebrafish embryos","volume":"265","author":"Huang","year":"2020","journal-title":"Environ. Pollut."},{"issue":"4","key":"10.1016\/j.cbpc.2026.110476_bb0035","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1080\/01635581.2023.2183546","article-title":"Cancer protective role of selected dietary polyphenols via modulating Keap1\/Nrf2\/ARE and interconnected signaling pathways","volume":"75","author":"Islam","year":"2023","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.cbpc.2026.110476_bb0040","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.chemosphere.2019.04.026","article-title":"Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway","volume":"227","author":"Jia","year":"2019","journal-title":"Chemosphere"},{"issue":"13","key":"10.1016\/j.cbpc.2026.110476_bb0045","doi-asserted-by":"crossref","first-page":"14318","DOI":"10.1007\/s11356-020-08138-z","article-title":"Trend of the research on rare earth elements in environmental science","volume":"27","author":"Kang","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"1","key":"10.1016\/j.cbpc.2026.110476_bb0050","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/jgh.14005","article-title":"Environmental contributions to gastrointestinal and liver cancer in the Asia-Pacific region","volume":"33","author":"Ko","year":"2018","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"17","key":"10.1016\/j.cbpc.2026.110476_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22179511","article-title":"Comparison of the effects of resveratrol and its derivatives on the radiation response of MCF-7 breast cancer cells","volume":"22","author":"Komorowska","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.cbpc.2026.110476_bb0060","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/j.jre.2018.12.016","article-title":"Rare earth elements in flotation products of coals from East Kootenay coalfields, British Columbia","volume":"37","author":"Kuppusamy","year":"2019","journal-title":"J. Rare Earths"},{"issue":"4","key":"10.1016\/j.cbpc.2026.110476_bb0065","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1007\/s12598-023-02584-7","article-title":"Rare earth element-modified MOF materials: synthesis and photocatalytic applications in environmental remediation","volume":"43","author":"Le","year":"2024","journal-title":"Rare Metals"},{"issue":"6","key":"10.1016\/j.cbpc.2026.110476_bb0070","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/j.chemosphere.2013.06.085","article-title":"A human health risk assessment of rare earth elements in soil and vegetables from a mining area in Fujian Province, Southeast China","volume":"93","author":"Li","year":"2013","journal-title":"Chemosphere"},{"issue":"3","key":"10.1016\/j.cbpc.2026.110476_bb0080","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s10661-013-3469-8","article-title":"State of rare earth elements in different environmental components in mining areas of China","volume":"186","author":"Liang","year":"2014","journal-title":"Environ. Monit. Assess."},{"issue":"11","key":"10.1016\/j.cbpc.2026.110476_bb0085","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19113516","article-title":"Toxicity evaluation and biomarker selection with validated reference gene in embryonic zebrafish exposed to Mitoxantrone","volume":"19","author":"Liu","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cbpc.2026.110476_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2021.105994","article-title":"Effect of rare earth element lanthanum on lipid deposition and Wnt10b signaling in the liver of male zebrafish","volume":"240","author":"Liu","year":"2021","journal-title":"Aquat. Toxicol."},{"issue":"12","key":"10.1016\/j.cbpc.2026.110476_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143911","article-title":"The mammalian \u201cObesogen\u201d tributyltin targets hepatic triglyceride accumulation and the transcriptional regulation of lipid metabolism in the liver and brain of zebrafish","volume":"10","author":"Lyssimachou","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.cbpc.2026.110476_bb0100","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1021\/acs.est.8b05547","article-title":"Environmental drivers of rare earth element bioaccumulation in freshwater zooplankton","volume":"53","author":"MacMillan Gwyneth","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2026.110476_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.126889","article-title":"Exposure to pyrimethanil induces developmental toxicity and cardiotoxicity in zebrafish","volume":"255","author":"Meng","year":"2020","journal-title":"Chemosphere"},{"issue":"8","key":"10.1016\/j.cbpc.2026.110476_bb0110","first-page":"689","article-title":"Resveratrol inhibits NF-\u03baB signaling through suppression of p65 and I\u03baB kinase activities","volume":"68","author":"Ren","year":"2013","journal-title":"Pharmazie"},{"issue":"14","key":"10.1016\/j.cbpc.2026.110476_bb0115","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1089\/ars.2015.6393","article-title":"Antioxidants in translational medicine","volume":"23","author":"Schmidt","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.cbpc.2026.110476_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131518","article-title":"Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues","volume":"285","author":"Stojsavljevic","year":"2021","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.cbpc.2026.110476_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0192404","article-title":"Euglena extract suppresses adipocyte-differentiation in human adipose-derived stem cells","volume":"13","author":"Sugimoto","year":"2018","journal-title":"PLoS One"},{"issue":"18","key":"10.1016\/j.cbpc.2026.110476_bb0130","doi-asserted-by":"crossref","DOI":"10.3390\/molecules29184283","article-title":"The aryl hydrocarbon receptor and its crosstalk: a chemopreventive target of naturally occurring and modified phytochemicals","volume":"29","author":"Szaefer","year":"2024","journal-title":"Molecules"},{"key":"10.1016\/j.cbpc.2026.110476_bb0135","article-title":"Rare earth elements in tropical soils, Cameroon soils (Central Africa)","volume":"25","author":"Temga","year":"2021","journal-title":"Geoderma Reg."},{"issue":"21","key":"10.1016\/j.cbpc.2026.110476_bb0140","doi-asserted-by":"crossref","first-page":"R1147","DOI":"10.1016\/j.cub.2017.09.019","article-title":"The liver","volume":"27","author":"Trefts","year":"2017","journal-title":"Curr. Biol."},{"issue":"8","key":"10.1016\/j.cbpc.2026.110476_bb0145","doi-asserted-by":"crossref","DOI":"10.5812\/hepatmon.12074","article-title":"Resveratrol: is it really good for liver health?","volume":"17","author":"Weiskirchen","year":"2017","journal-title":"Hepat. Mon."},{"key":"10.1016\/j.cbpc.2026.110476_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124423","article-title":"Immunotoxicity and transcriptome analysis of zebrafish embryos in response to glufosinate-ammonium exposure","volume":"236","author":"Xiong","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2026.110476_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.137213","article-title":"Toxicity of rare earth elements europium and samarium on zebrafish development and locomotor performance","volume":"487","author":"Yang","year":"2025","journal-title":"J. Hazard. Mater."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110476_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/toxins12020107","article-title":"Chronic microcystin-LR exposure induces abnormal lipid metabolism via endoplasmic reticulum stress in male zebrafish","volume":"12","author":"Zhang","year":"2020","journal-title":"Toxins"},{"issue":"1","key":"10.1016\/j.cbpc.2026.110476_bb0165","article-title":"Effects of rare earth elements on bacteria in rhizosphere, root, phyllosphere and leaf of soil-rice ecosystem","volume":"12","author":"Zhang","year":"2022","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110476_bb0170","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1021\/acs.est.0c06632","article-title":"Rare earth elements lanthanum and praseodymium adversely affect neural and cardiovascular development in zebrafish (Danio rerio)","volume":"55","author":"Zhao","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.cbpc.2026.110476_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132621","article-title":"The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius)","volume":"461","author":"Zhao","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2026.110476_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117323","article-title":"Effect of flupyradifurone on zebrafish embryonic development","volume":"285","author":"Zhong","year":"2021","journal-title":"Environ. Pollut."},{"issue":"11","key":"10.1016\/j.cbpc.2026.110476_bb0185","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.6023\/A23070323","article-title":"Rare earth biological manufacturing and high value-added material application","volume":"81","author":"Zhong","year":"2023","journal-title":"Acta Chim. Sin."}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045626000347?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045626000347?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T12:32:20Z","timestamp":1771417940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045626000347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":36,"alternative-id":["S1532045626000347"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2026.110476","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rare earth element erbium induces hepatotoxicity in zebrafish","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2026.110476","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110476"}}