{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:51:50Z","timestamp":1791345110789,"version":"4.3.1"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.cbpc.2026.110665","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:41:25Z","timestamp":1787614885000},"page":"110665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Astaxanthin alleviates dibutyl phthalate-induced cardiotoxicity in zebrafish larvae by regulating mitophagy"],"prefix":"10.1016","volume":"310","author":[{"given":"Jing","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"38","key":"10.1016\/j.cbpc.2026.110665_bb0005","doi-asserted-by":"crossref","first-page":"42887","DOI":"10.1021\/acsami.2c10506","article-title":"Astaxanthin activated the Nrf2\/HO-1 pathway to enhance autophagy and inhibit Ferroptosis, ameliorating acetaminophen-induced liver injury","volume":"14","author":"Cai","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"20","key":"10.1016\/j.cbpc.2026.110665_bb0010","doi-asserted-by":"crossref","DOI":"10.3390\/cells11203187","article-title":"Shikonin inhibits fin regeneration in zebrafish larvae","volume":"11","author":"Cao","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.cbpc.2026.110665_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124496","article-title":"Remediation strategies for mitigation of phthalate pollution: challenges and future perspectives","volume":"409","author":"Das","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.cbpc.2026.110665_bb0020","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.chemosphere.2017.11.042","article-title":"Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels","volume":"193","author":"Dong","year":"2018","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.cbpc.2026.110665_bb0025","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17010103","article-title":"Free radical scavenging and cellular antioxidant properties of astaxanthin","volume":"17","author":"Dose","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.cbpc.2026.110665_bb0030","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1038\/nm.4222","article-title":"Cardioprotection and lifespan extension by the natural polyamine spermidine","volume":"22","author":"Eisenberg","year":"2016","journal-title":"Nat. Med."},{"issue":"13","key":"10.1016\/j.cbpc.2026.110665_bb0035","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.70714","article-title":"Astaxanthin prevented acute alcoholic cardiomyopathy by maintenance of mitophagy-mediated mitochondrial homeostasis","volume":"29","author":"Fan","year":"2025","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.cbpc.2026.110665_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2022.105430","article-title":"A preliminary cumulative risk assessment of diethylhexyl phthalate and dibutyl phthalate based on the inhibition of embryonic development via the PPAR\u03b3 pathway","volume":"84","author":"Fang","year":"2022","journal-title":"Toxicol. in Vitro"},{"issue":"7708","key":"10.1016\/j.cbpc.2026.110665_bb0045","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/s41586-018-0162-7","article-title":"Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice","volume":"558","author":"Fern\u00e1ndez","year":"2018","journal-title":"Nature"},{"issue":"14","key":"10.1016\/j.cbpc.2026.110665_bb0050","first-page":"7722","article-title":"Astaxanthin protecting myocardial cells from hypoxia\/reoxygenation injury by regulating miR-138\/HIF-1\u03b1 axis","volume":"24","author":"Gai","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0055","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s10616-019-00300-x","article-title":"Phthalates affect the in vitro expansion of human hematopoietic stem cell","volume":"71","author":"Guti\u00e9rrez-Garc\u00eda","year":"2019","journal-title":"Cytotechnology"},{"issue":"1","key":"10.1016\/j.cbpc.2026.110665_bb0060","article-title":"Astaxanthin mitigates cardiac toxicity induced via doxorubicin by alleviating mitochondrial fission and autophagy in rats","volume":"15","author":"He","year":"2025","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0065","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/10408690590957188","article-title":"Astaxanthin: a review of its chemistry and applications","volume":"46","author":"Higuera-Ciapara","year":"2006","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.cbpc.2026.110665_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115911","article-title":"Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway","volume":"270","author":"Hu","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2026.110665_bb0075","article-title":"Autophagy at the synapse, an early site of dysfunction in neurodegeneration","volume":"32","author":"Jasutkar","year":"2023","journal-title":"Curr. Opin. Physiol."},{"issue":"Pt D","key":"10.1016\/j.cbpc.2026.110665_bb0080","article-title":"Dibutyl phthalate induced oxidative stress and genotoxicity on adult zebrafish (Danio rerio) brain","volume":"424","author":"Jiang","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"6","key":"10.1016\/j.cbpc.2026.110665_bb0085","doi-asserted-by":"crossref","DOI":"10.3390\/nu12061896","article-title":"Effects of 3-month astaxanthin supplementation on cardiac function in heart failure patients with left ventricular systolic dysfunction-a pilot study","volume":"12","author":"Kato","year":"2020","journal-title":"Nutrients"},{"issue":"15","key":"10.1016\/j.cbpc.2026.110665_bb0090","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22157964","article-title":"Mitochondrion as a target of Astaxanthin therapy in heart failure","volume":"22","author":"Krestinina","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.cbpc.2026.110665_bb0095","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1007\/s10741-021-10109-6","article-title":"Mitochondrial abnormalities: a hub in metabolic syndrome-related cardiac dysfunction caused by oxidative stress","volume":"27","author":"Li","year":"2022","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.cbpc.2026.110665_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.164620","article-title":"Dibutyl phthalate causes heart damage by disrupting Ca2+ transfer from endoplasmic reticulum to mitochondria and triggering subsequent pyroptosis","volume":"892","author":"Li","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"8","key":"10.1016\/j.cbpc.2026.110665_bb0105","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13187","article-title":"Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart","volume":"19","author":"Liang","year":"2020","journal-title":"Aging Cell"},{"issue":"10","key":"10.1016\/j.cbpc.2026.110665_bb0110","doi-asserted-by":"crossref","DOI":"10.3390\/toxics13100815","article-title":"Probing the cardiovascular toxic effects of long-term exposure to dibutyl phthalate in Sprague-Dawley rats based on oxidative inflammation and metabolic pathways: implications for the heart and blood vessel","volume":"13","author":"Liang","year":"2025","journal-title":"Toxics"},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0115","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10741-007-9079-1","article-title":"Mitochondrial centrality in heart failure","volume":"13","author":"Mar\u00edn-Garc\u00eda","year":"2008","journal-title":"Heart Fail. Rev."},{"issue":"48","key":"10.1016\/j.cbpc.2026.110665_bb0120","doi-asserted-by":"crossref","first-page":"19202","DOI":"10.1021\/acs.est.3c03401","article-title":"Longitudinal associations between prenatal exposure to phthalates and steroid hormones in maternal hair samples from the SEPAGES cohort","volume":"57","author":"Mustieles","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"6","key":"10.1016\/j.cbpc.2026.110665_bb0125","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1021\/acs.jafc.7b05493","article-title":"Astaxanthin induces the Nrf2\/HO-1 antioxidant pathway in human umbilical vein endothelial cells by generating trace amounts of ROS","volume":"66","author":"Niu","year":"2018","journal-title":"J. Agric. Food Chem."},{"issue":"8","key":"10.1016\/j.cbpc.2026.110665_bb0130","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1002\/1873-3468.14060","article-title":"Mitochondrial clearance: mechanisms and roles in cellular fitness","volume":"595","author":"Onishi","year":"2021","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cbpc.2026.110665_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.mrgentox.2023.503702","article-title":"Evidence of genotoxicity, neurotoxicity, and antioxidant imbalance in silver catfish Rhamdia quelen after subchronic exposure to diisopentyl phthalate","volume":"892","author":"Oya-Silva","year":"2023","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"key":"10.1016\/j.cbpc.2026.110665_bb0140","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-94-007-2869-1_1","article-title":"The oxidative phosphorylation system in mammalian mitochondria","volume":"942","author":"Papa","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"issue":"4","key":"10.1016\/j.cbpc.2026.110665_bb0145","doi-asserted-by":"crossref","first-page":"R170","DOI":"10.1016\/j.cub.2018.01.004","article-title":"Mitophagy and quality control mechanisms in mitochondrial maintenance","volume":"28","author":"Pickles","year":"2018","journal-title":"Curr. Biol."},{"issue":"10","key":"10.1016\/j.cbpc.2026.110665_bb0150","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201601077","article-title":"\u03b2-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice","volume":"61","author":"Pongkan","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.cbpc.2026.110665_bb0155","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1038\/ncomms3300","article-title":"Overexpression of Atg5 in mice activates autophagy and extends lifespan","volume":"4","author":"Pyo","year":"2013","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0160","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1172\/JCI122035","article-title":"An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia","volume":"129","author":"Saito","year":"2019","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.cbpc.2026.110665_bb0165","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tibs.2010.07.007","article-title":"Regulation of autophagy by ROS: physiology and pathology","volume":"36","author":"Scherz-Shouval","year":"2011","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cbpc.2026.110665_bb0170","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.6584","article-title":"Acute toxicity and responses of antioxidant systems to dibutyl phthalate in neonate and adult Daphnia magna","volume":"7","author":"Shen","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.cbpc.2026.110665_bb0175","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0045-6535(97)00195-1","article-title":"The environmental fate of phthalate esters: a literature review","volume":"35","author":"Staples","year":"1997","journal-title":"Chemosphere"},{"issue":"9","key":"10.1016\/j.cbpc.2026.110665_bb0180","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1080\/15548627.2020.1822097","article-title":"Mitophagy in degenerative joint diseases","volume":"17","author":"Sun","year":"2021","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.cbpc.2026.110665_bb0185","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4161\/auto.5618","article-title":"Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans","volume":"4","author":"T\u00f3th","year":"2008","journal-title":"Autophagy"},{"issue":"5","key":"10.1016\/j.cbpc.2026.110665_bb0190","doi-asserted-by":"crossref","DOI":"10.3390\/healthcare9050603","article-title":"Phthalates and their impacts on human health","volume":"9","author":"Wang","year":"2021","journal-title":"Healthcare"},{"key":"10.1016\/j.cbpc.2026.110665_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.130256","article-title":"A review on efficient removal of phthalic acid esters via biochars and transition metals-activated persulfate systems","volume":"277","author":"Xiong","year":"2021","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0200","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.fsi.2015.04.033","article-title":"Assessment of immunotoxicity of dibutyl phthalate using live zebrafish embryos","volume":"45","author":"Xu","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"5","key":"10.1016\/j.cbpc.2026.110665_bb0205","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/tox.23084","article-title":"Nimodipine attenuates dibutyl phthalate-induced learning and memory impairment in kun ming mice: an in vivo study based on bioinformatics analysis","volume":"36","author":"Yan","year":"2021","journal-title":"Environ. Toxicol."},{"issue":"9","key":"10.1016\/j.cbpc.2026.110665_bb0210","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.bbadis.2019.05.007","article-title":"Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury","volume":"1865","author":"Yang","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.cbpc.2026.110665_bb0215","article-title":"Synergies of dibutyl phthalate on high-fat diet can aggravate cardiac fibrosis\/dysfunction and the protective effects of vitamin E and salidroside: a molecular toxicological study in Sprague-Dawley rats","volume":"302","author":"Yang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.cbpc.2026.110665_bb0220","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/mnfr.201000414","article-title":"Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae","volume":"55","author":"Yuan","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"issue":"11","key":"10.1016\/j.cbpc.2026.110665_bb0225","first-page":"4099","article-title":"The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4\/NF-\u03baB signaling pathway","volume":"25","author":"Zaafan","year":"2021","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"9","key":"10.1016\/j.cbpc.2026.110665_bb0230","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1111\/jcmm.12609","article-title":"Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission","volume":"19","author":"Zhang","year":"2015","journal-title":"J. Cell. Mol. Med."},{"issue":"Pt 1","key":"10.1016\/j.cbpc.2026.110665_bb0235","article-title":"Gut microbiota may contribute to the postnatal male reproductive abnormalities induced by prenatal dibutyl phthalate exposure","volume":"287","author":"Zhang","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.cbpc.2026.110665_bb0240","article-title":"MCOLN1 is a ROS sensor in lysosomes that regulates autophagy","volume":"7","author":"Zhang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cbpc.2026.110665_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2020.122845","article-title":"Anthraquinone-2,6-disulfonate enhanced biodegradation of dibutyl phthalate: reducing membrane damage and oxidative stress in bacterial degradation","volume":"302","author":"Zhang","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.cbpc.2026.110665_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110740","article-title":"Dibutyl phthalate aggravated asthma-like symptoms through oxidative stress and increasing calcitonin gene-related peptide release","volume":"199","author":"Zhou","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.cbpc.2026.110665_bb0255","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jhazmat.2015.06.024","article-title":"Chromophoric dissolved organic matter of black waters in a highly eutrophic Chinese lake: freshly produced from algal scums?","volume":"299","author":"Zhou","year":"2015","journal-title":"J. Hazard. Mater."},{"issue":"2","key":"10.1016\/j.cbpc.2026.110665_bb0260","doi-asserted-by":"crossref","DOI":"10.3390\/toxins16020068","article-title":"Protective effects of astaxanthin on ochratoxin A-induced liver injury: effects of endoplasmic reticulum stress and mitochondrial fission-fusion balance","volume":"16","author":"Zou","year":"2024","journal-title":"Toxins (Basel)"}],"container-title":["Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045626002231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1532045626002231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:29:09Z","timestamp":1791343749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1532045626002231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":52,"alternative-id":["S1532045626002231"],"URL":"https:\/\/doi.org\/10.1016\/j.cbpc.2026.110665","relation":{},"ISSN":["1532-0456"],"issn-type":[{"value":"1532-0456","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Astaxanthin alleviates dibutyl phthalate-induced cardiotoxicity in zebrafish larvae by regulating mitophagy","name":"articletitle","label":"Article Title"},{"value":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cbpc.2026.110665","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110665"}}