{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T17:13:23Z","timestamp":1784394803461,"version":"3.55.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.cca.2005.10.029","type":"journal-article","created":{"date-parts":[[2006,2,10]],"date-time":"2006-02-10T12:29:39Z","timestamp":1139574579000},"page":"28-35","source":"Crossref","is-referenced-by-count":55,"title":["Novel biomarkers in malignant melanoma"],"prefix":"10.1016","volume":"367","author":[{"given":"Anja K.","family":"Bosserhoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2005.10.029_bib1","first-page":"51","article-title":"Expression of CD44s and CD44 splice variants in human melanoma","volume":"9","author":"Ranuncolo","year":"2002","journal-title":"Oncol Rep"},{"key":"10.1016\/j.cca.2005.10.029_bib2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1054\/bjps.2002.3964","article-title":"The c-myc oncogene: use of a biological prognostic marker as a potential target for gene therapy in melanoma","volume":"55","author":"Chana","year":"2002","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.cca.2005.10.029_bib3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00008390-200402000-00004","article-title":"Cytoplasmic expression of nm23 predicts the potential for cerebral metastasis in patients with primary cutaneous melanoma","volume":"14","author":"Sarris","year":"2004","journal-title":"Melanoma Res"},{"key":"10.1016\/j.cca.2005.10.029_bib4","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1046\/j.1365-2133.2001.04336.x","article-title":"Loss of beta-catenin expression associated with disease progression in malignant melanoma","volume":"145","author":"Kageshita","year":"2001","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.cca.2005.10.029_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1097\/01.SAP.0000032308.89737.EA","article-title":"Use of oncogene expression as an independent prognostic marker for primary melanoma","volume":"50","author":"Grover","year":"2003","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.cca.2005.10.029_bib6","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1034\/j.1600-0463.2003.t01-1-1110207.x","article-title":"ICAM-1 and beta(3) integrin immunoexpression in malignant melanoma cells: can they be used as additional predictors?","volume":"111","author":"Haritopoulos","year":"2003","journal-title":"APMIS"},{"key":"10.1016\/j.cca.2005.10.029_bib7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00008390-200402000-00005","article-title":"Integrin chains beta1 and alphav as prognostic factors in human metastatic melanoma","volume":"14","author":"Nikkola","year":"2004","journal-title":"Melanoma Res"},{"key":"10.1016\/j.cca.2005.10.029_bib8","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s10555-005-1574-z","article-title":"A Wnt-er Wonderland\u2014The complexity of Wnt signaling in melanoma","volume":"24","author":"Weeraratna","year":"2005","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.cca.2005.10.029_bib9","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10555-005-5865-1","article-title":"The role of B-RAF in melanoma","volume":"24","author":"Gray-Schopfer","year":"2005","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.cca.2005.10.029_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s10555-005-1577-9","article-title":"Functional and therapeutic significance of Akt deregulation in malignant melanoma","volume":"24","author":"Robertson","year":"2005","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.cca.2005.10.029_bib11","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1200\/JCO.2005.07.168","article-title":"Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases","volume":"23","author":"Dai","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cca.2005.10.029_bib12","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0002-9440(10)64922-X","article-title":"Importance of vascular phenotype by basic fibroblast growth factor, and influence of the angiogenic factors basic fibroblast growth factor\/fibroblast growth factor receptor-1 and ephrin-A1\/EphA2 on melanoma progression","volume":"160","author":"Straume","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib13","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/(SICI)1097-0215(19991022)84:5<494::AID-IJC8>3.0.CO;2-O","article-title":"Up-regulation of ephrin-A1 during melanoma progression","volume":"84","author":"Easty","year":"1999","journal-title":"Int J Cancer"},{"key":"10.1016\/j.cca.2005.10.029_bib14","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/path.1300","article-title":"Apoptosis and melanoma: molecular mechanisms","volume":"199","author":"Hussein","year":"2003","journal-title":"J Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1083\/jcb.200409171","article-title":"Cell differentiation: reciprocal regulation of Apaf-1 and the inhibitor of apoptosis proteins","volume":"167","author":"Lindholm","year":"2004","journal-title":"J Cell Biol"},{"key":"10.1016\/j.cca.2005.10.029_bib16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0300-9084(02)01376-7","article-title":"The Apaf-1 apoptosome: a large caspase-activating complex","volume":"84","author":"Cain","year":"2002","journal-title":"Biochimie"},{"key":"10.1016\/j.cca.2005.10.029_bib17","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/35051606","article-title":"Inactivation of the apoptosis effector Apaf-1 in malignant melanoma","volume":"409","author":"Soengas","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.cca.2005.10.029_bib18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0749.2004.00205.x","article-title":"Decreased expression of Apaf-1 with progression of melanoma","volume":"18","author":"Mustika","year":"2005","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.cca.2005.10.029_bib19","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/sj.bjc.6602092","article-title":"Reduced Apaf-1 expression in human cutaneous melanomas","volume":"91","author":"Dai","year":"2004","journal-title":"Br J Cancer"},{"key":"10.1016\/j.cca.2005.10.029_bib20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.0906-6705.2004.00136.x","article-title":"Analysis of APAF-1 expression in human cutaneous melanoma progression","volume":"13","author":"Baldi","year":"2004","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.cca.2005.10.029_bib21","doi-asserted-by":"crossref","first-page":"8590","DOI":"10.1038\/sj.onc.1207102","article-title":"The Bcl-2 family: roles in cell survival and oncogenesis","volume":"22","author":"Cory","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.cca.2005.10.029_bib22","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00000372-199502000-00002","article-title":"Bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi","volume":"17","author":"Cerroni","year":"1995","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.cca.2005.10.029_bib23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000059574","article-title":"Immunohistochemically detectable bcl-2 expression in metastatic melanoma: association with survival and treatment response","volume":"62","author":"Vlaykova","year":"2002","journal-title":"Oncology"},{"key":"10.1016\/j.cca.2005.10.029_bib24","doi-asserted-by":"crossref","first-page":"8773","DOI":"10.1158\/0008-5472.CAN-04-1387","article-title":"Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma","volume":"64","author":"Divito","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2005.10.029_bib25","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1126\/science.1071549","article-title":"The promise and perils of Wnt signaling through beta-catenin","volume":"296","author":"Moon","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.cca.2005.10.029_bib26","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/(SICI)1521-1878(199912)22:1<1021::AID-BIES6>3.0.CO;2-P","article-title":"Beta-catenin signaling and cancer","volume":"21","author":"Morin","year":"1999","journal-title":"Bioessays"},{"issue":"103","key":"10.1016\/j.cca.2005.10.029_bib27","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/ijc.10893","article-title":"Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome","volume":"%20","author":"Kielhorn","year":"2003","journal-title":"Int J Cancer"},{"key":"10.1016\/j.cca.2005.10.029_bib28","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10555-005-1572-1","article-title":"Integrin signaling in malignant melanoma","volume":"24","author":"Kuphal","year":"2005","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.cca.2005.10.029_bib29","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1600-0749.2005.00235.x","article-title":"Adhesion, migration and communication in melanocytes and melanoma","volume":"18","author":"Haass","year":"2005","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.cca.2005.10.029_bib30","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/01.PRS.0000148417.86768.C9","article-title":"Development of a tissue array for primary melanoma with long-term follow-up: discovering melanoma cell adhesion molecule as an important prognostic marker","volume":"115","author":"Pacifico","year":"2005","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.cca.2005.10.029_bib31","doi-asserted-by":"crossref","first-page":"35696","DOI":"10.1074\/jbc.M205319200","article-title":"Inhibition of prostate tumor angiogenesis by the tumor suppressor CEACAM1","volume":"277","author":"Volpert","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cca.2005.10.029_bib32","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1053\/hupa.2002.32218","article-title":"Down-regulation of CEACAM1 in human prostate cancer: correlation with loss of cell polarity, increased proliferation rate, and Gleason grade 3 to 4 transition","volume":"33","author":"Busch","year":"2002","journal-title":"Hum Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib33","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1200\/JCO.2002.05.033","article-title":"CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease","volume":"20","author":"Thies","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cca.2005.10.029_bib34","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/S0002-9440(10)63433-5","article-title":"CEACAM1 enhances invasion and migration of melanocytic and melanoma cells","volume":"165","author":"Ebrahimnejad","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib35","doi-asserted-by":"crossref","first-page":"5270","DOI":"10.1158\/0008-5472.CAN-04-0731","article-title":"Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas","volume":"64","author":"Hoek","year":"2004","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2005.10.029_bib36","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.yexcr.2005.01.024","article-title":"A secreted form of P-cadherin is expressed in malignant melanoma","volume":"305","author":"Bauer","year":"2005","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.cca.2005.10.029_bib37","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/01.sap.0000171429.19320.ce","article-title":"Identification of P-cadherin in primary melanoma using a tissue microarrayer: prognostic implications in a patient cohort with long-term follow up","volume":"55","author":"Pacifico","year":"2005","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.cca.2005.10.029_bib38","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jdermsci.2004.03.002","article-title":"Chemokine receptors and melanoma metastasis","volume":"36","author":"Murakami","year":"2004","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.cca.2005.10.029_bib39","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1046\/j.1523-1747.2002.01725.x","article-title":"The role of chemokines in melanoma tumor growth and metastasis","volume":"118","author":"Payne","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.cca.2005.10.029_bib40","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1158\/1078-0432.CCR-04-1887","article-title":"Expression of CXCR4 predicts poor prognosis in patients with malignant melanoma","volume":"11","author":"Scala","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.cca.2005.10.029_bib41","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/ijc.21269","article-title":"Clinical significance of CXCR3 and CXCR4 expression in primary melanoma","volume":"117","author":"Longo-Imedio","year":"2005","journal-title":"Int J Cancer"},{"key":"10.1016\/j.cca.2005.10.029_bib42","doi-asserted-by":"crossref","first-page":"37S","DOI":"10.1016\/S0002-9343(99)00115-1","article-title":"Role and regulation of cyclooxygenase-2 during inflammation","volume":"106","author":"Simon","year":"1999","journal-title":"Am J Med"},{"key":"10.1016\/j.cca.2005.10.029_bib43","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/0470856734.ch16","article-title":"Cyclooxygenase 2: from inflammation to carcinogenesis","volume":"256","author":"Ristimaki","year":"2004","journal-title":"Novartis Found Symp"},{"key":"10.1016\/j.cca.2005.10.029_bib44","first-page":"303","article-title":"Expression of cyclooxygenase 2 in human malignant melanoma","volume":"61","author":"Denkert","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2005.10.029_bib45","doi-asserted-by":"crossref","first-page":"713","DOI":"10.4161\/cbt.2.6.627","article-title":"Analysis of cyclooxygenase 2 (COX-2) expression during malignant melanoma progression","volume":"2","author":"Goulet","year":"2003","journal-title":"Cancer Biol Ther"},{"key":"10.1016\/j.cca.2005.10.029_bib46","first-page":"173","article-title":"Transcription factors involved in development and progression of malignant melanoma","volume":"19","author":"Poser","year":"2004","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.cca.2005.10.029_bib47","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1247\/csf.26.19","article-title":"Role of ETS family transcription factors in vascular development and angiogenesis","volume":"26","author":"Sato","year":"2001","journal-title":"Cell Struct Funct"},{"key":"10.1016\/j.cca.2005.10.029_bib48","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0968-0004(92)90404-W","article-title":"The ets gene family","volume":"17","author":"Macleod","year":"1992","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.cca.2005.10.029_bib49","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s00018-003-3337-8","article-title":"The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma","volume":"61","author":"Rothhammer","year":"2004","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.cca.2005.10.029_bib50","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1038\/modpathol.3800206","article-title":"Ets-1 transcription factor is widely expressed in benign and malignant melanocytes and its expression has no significant association with prognosis","volume":"17","author":"Torlakovic","year":"2004","journal-title":"Mod Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib51","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1097\/01.MP.0000082395.59356.4F","article-title":"Expression of the ets-1 proto-oncogene in melanocytic lesions","volume":"16","author":"Keehn","year":"2003","journal-title":"Mod Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib52","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.biocel.2004.08.012","article-title":"Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators","volume":"37","author":"Dery","year":"2005","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.cca.2005.10.029_bib53","doi-asserted-by":"crossref","first-page":"4991","DOI":"10.1200\/JCO.2004.05.061","article-title":"Role of VHL gene mutation in human cancer","volume":"22","author":"Kim","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.cca.2005.10.029_bib54","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0074-7696(04)42004-X","article-title":"The hypoxia-inducible factor and tumor progression along the angiogenic pathway","volume":"242","author":"Brahimi-Horn","year":"2005","journal-title":"Int Rev Cytol"},{"key":"10.1016\/j.cca.2005.10.029_bib55","doi-asserted-by":"crossref","first-page":"492","DOI":"10.4161\/cbt.3.6.1010","article-title":"Regulation of transcription and translation by hypoxia","volume":"3","author":"Liu","year":"2004","journal-title":"Cancer Biol Ther"},{"key":"10.1016\/j.cca.2005.10.029_bib56","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/00008390-200310000-00008","article-title":"Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin","volume":"13","author":"Giatromanolaki","year":"2003","journal-title":"Melanoma Res"},{"key":"10.1016\/j.cca.2005.10.029_bib57","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev.genet.38.072902.092717","article-title":"Melanocytes and the microphthalmia transcription factor network","volume":"38","author":"Steingrimsson","year":"2004","journal-title":"Annu Rev Genet"},{"key":"10.1016\/j.cca.2005.10.029_bib58","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1038\/sj.onc.1206443","article-title":"Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival","volume":"22","author":"Widlund","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.cca.2005.10.029_bib59","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1101\/gad.14.14.1712","article-title":"Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage","volume":"14","author":"Goding","year":"2000","journal-title":"Genes Dev"},{"key":"10.1016\/j.cca.2005.10.029_bib60","first-page":"318","article-title":"Microphthalmia transcription factor: a specific marker for malignant melanoma","volume":"105","author":"Vachtenheim","year":"2004","journal-title":"Prague Med Rep"},{"key":"10.1016\/j.cca.2005.10.029_bib61","first-page":"5012","article-title":"Micropthalmia transcription factor: a new prognostic marker in intermediate-thickness cutaneous malignant melanoma","volume":"60","author":"Salti","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2005.10.029_bib62","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/cncr.9049","article-title":"Microphthalmia transcription factor: a sensitive and specific marker for malignant melanoma in cytologic specimens","volume":"93","author":"Dorvault","year":"2001","journal-title":"Cancer"},{"key":"10.1016\/j.cca.2005.10.029_bib63","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00022744-200203000-00008","article-title":"Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma","volume":"10","author":"Granter","year":"2002","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.cca.2005.10.029_bib64","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00000478-200101000-00005","article-title":"Microphthalmia transcription factor expression in cutaneous benign, malignant melanocytic, and nonmelanocytic tumors","volume":"25","author":"King","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib65","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0002-9440(10)63695-4","article-title":"Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma","volume":"163","author":"Behrmann","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib66","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/00000372-200302000-00002","article-title":"Gene expression profiling of melanocytic lesions","volume":"25","author":"Seykora","year":"2003","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.cca.2005.10.029_bib67","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00062752-199901000-00008","article-title":"Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors","volume":"6","author":"Zhang","year":"1999","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.cca.2005.10.029_bib68","first-page":"151","article-title":"Pleiotrophin and midkine in normal development and tumor biology","volume":"6","author":"Kurtz","year":"1995","journal-title":"Crit Rev Oncog"},{"key":"10.1016\/j.cca.2005.10.029_bib69","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.0303-6987.2005.00282.x","article-title":"Pleiotrophin expression correlates with melanocytic tumor progression and metastatic potential","volume":"32","author":"Wu","year":"2005","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib70","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/35065617","article-title":"Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase","volume":"410","author":"Toyoshima-Morimoto","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.cca.2005.10.029_bib71","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1006\/bbrc.1997.6633","article-title":"Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase","volume":"234","author":"Smith","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.cca.2005.10.029_bib72","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1034\/j.1600-0560.2002.290605.x","article-title":"Expression of polo-like kinase (PLK1) in thin melanomas: a novel marker of metastatic disease","volume":"29","author":"Kneisel","year":"2002","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib73","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S1535-6108(03)00249-6","article-title":"No PUMA, no death: implications for p53-dependent apoptosis","volume":"4","author":"Yu","year":"2003","journal-title":"Cancer Cell"},{"key":"10.1016\/j.cca.2005.10.029_bib74","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/sj.cdd.4400998","article-title":"Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins","volume":"9","author":"Puthalakath","year":"2002","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.cca.2005.10.029_bib75","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1038\/sj.onc.1208374","article-title":"PUMA expression is significantly reduced in human cutaneous melanomas","volume":"24","author":"Karst","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.cca.2005.10.029_bib76","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s00467-004-1766-8","article-title":"Suppressors of cytokine signaling in health and disease","volume":"20","author":"Tan","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.cca.2005.10.029_bib77","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1172\/JCI24228","article-title":"Knock your SOCS off!","volume":"115","author":"Leroith","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.cca.2005.10.029_bib78","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.it.2003.10.008","article-title":"Regulation of cytokine signaling by SOCS family molecules","volume":"24","author":"Fujimoto","year":"2003","journal-title":"Trends Immunol"},{"key":"10.1016\/j.cca.2005.10.029_bib79","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.0022-202X.2004.23408.x","article-title":"Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma","volume":"123","author":"Li","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.cca.2005.10.029_bib80","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1136\/mp.56.5.280","article-title":"Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features","volume":"56","author":"Pham","year":"2003","journal-title":"Mol Pathol"},{"key":"10.1016\/j.cca.2005.10.029_bib81","doi-asserted-by":"crossref","first-page":"D1005","DOI":"10.2741\/A341","article-title":"Molecular events in melanoma development and progression","volume":"3","author":"Meier","year":"1998","journal-title":"Front Biosci"},{"key":"10.1016\/j.cca.2005.10.029_bib82","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/BF00046337","article-title":"Human melanoma: development and progression","volume":"9","author":"Herlyn","year":"1990","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.cca.2005.10.029_bib83","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/35020115","article-title":"Molecular classification of cutaneous malignant melanoma by gene expression profiling","volume":"406","author":"Bittner","year":"2000","journal-title":"Nature"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898106000179?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898106000179?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T21:38:26Z","timestamp":1706909906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898106000179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":83,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0009898106000179"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2005.10.029","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}