{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:27:43Z","timestamp":1791080863926,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.cca.2008.07.014","type":"journal-article","created":{"date-parts":[[2008,7,19]],"date-time":"2008-07-19T08:20:46Z","timestamp":1216455646000},"page":"42-47","source":"Crossref","is-referenced-by-count":19,"title":["Low-density lipoprotein (LDL), which includes apolipoprotein A-I (apoAI-LDL) as a novel marker of coronary artery disease"],"prefix":"10.1016","volume":"397","author":[{"given":"Ken","family":"Ogasawara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Mashiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiho","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Matsuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiro","family":"Takeya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Yajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2008.07.014_bib1","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cca.2008.07.014_bib2","doi-asserted-by":"crossref","first-page":"C7","DOI":"10.1016\/j.jacc.2005.09.068","article-title":"Pathogenesis of atherosclerosis","volume":"47","author":"Falk","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cca.2008.07.014_bib3","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1161\/01.ATV.0000033829.14012.18","article-title":"Oxidized LDL in carotid plaques and plasma associates with plaque instability","volume":"22","author":"Nishi","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.cca.2008.07.014_bib4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1050-1738(01)00111-6","article-title":"The oxidative modification hypothesis of atherosclerosis: does it hold for humans?","volume":"11","author":"Witzum","year":"2001","journal-title":"Trendds Cardiovasc Med"},{"key":"10.1016\/j.cca.2008.07.014_bib5","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1161\/01.CIR.103.15.1955","article-title":"Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndrome","volume":"103","author":"Ebara","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.07.014_bib6","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1056\/NEJMoa043175","article-title":"Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease","volume":"353","author":"Tsimikas","year":"2005","journal-title":"New Engl J Med"},{"key":"10.1016\/j.cca.2008.07.014_bib7","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1161\/01.CIR.98.15.1487","article-title":"Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease","volume":"98","author":"Holvoet","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.07.014_bib8","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1161\/01.CIR.103.15.1930","article-title":"Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk","volume":"103","author":"Tsimikas","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.07.014_bib9","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1161\/CIRCULATIONAHA.104.529297","article-title":"Plasma oxidized low density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population","volume":"112","author":"Meisinger","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.07.014_bib10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0021-9150(03)00053-4","article-title":"The SOLOS Study Investigators. High oxidative stress in patients with stable coronary heart disease","volume":"168","author":"Weinbrener","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.cca.2008.07.014_bib11","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.amjcard.2007.09.072","article-title":"Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein","volume":"100","author":"Ridker","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cca.2008.07.014_bib12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1080\/07853890701749225","article-title":"The connection between C-reactive protein and atherosclerosis","volume":"40","author":"Singh","year":"2008","journal-title":"Ann Med"},{"key":"10.1016\/j.cca.2008.07.014_bib13","doi-asserted-by":"crossref","first-page":"166.e17","DOI":"10.1016\/j.amjmed.2005.06.057","article-title":"What does minor elevation of C-reactive protein signify?","volume":"119","author":"Kushner","year":"2006","journal-title":"Am J Med"},{"key":"10.1016\/j.cca.2008.07.014_bib14","doi-asserted-by":"crossref","first-page":"10316","DOI":"10.1073\/pnas.89.21.10316","article-title":"High density lipoprotein is the major carrier of lipid hydroperoxides in fasted human plasma","volume":"89","author":"Bowry","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.cca.2008.07.014_bib15","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cca.2006.11.002","article-title":"Establishment and evaluation of 2 monoclonal antibodies against oxidized apolipoprotein A-I (apoA-I) and its application to determine blood oxidized apoA-I levels","volume":"378","author":"Ueda","year":"2007","journal-title":"Clinica Chimica Acta"},{"key":"10.1016\/j.cca.2008.07.014_bib16","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1161\/hq1101.098232","article-title":"In vivo complex formation of oxidized a1-antitrypsin and LDL","volume":"21","author":"Mashiba","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.cca.2008.07.014_bib17","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.atherosclerosis.2004.01.030","article-title":"A serum amyloid A and LDL complex as a new prognostic marker in stable coronary artery disease","volume":"174","author":"Ogasawara","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.cca.2008.07.014_bib18","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1161\/01.CIR.80.2.410","article-title":"Unstable angina \u2014 a classification","volume":"80","author":"Braunwald","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.07.014_bib19","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0022-2275(20)42943-8","article-title":"Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions","volume":"11","author":"Burstein","year":"1970","journal-title":"J Lipid Res"},{"key":"10.1016\/j.cca.2008.07.014_bib20","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1194\/jlr.M200256-JLR200","article-title":"Characterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoprotein","volume":"44","author":"Pankhurst","year":"2003","journal-title":"J Lipid Res"},{"key":"10.1016\/j.cca.2008.07.014_bib21","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1056\/NEJMoa042000","article-title":"Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease","volume":"352","author":"Nissen","year":"2005","journal-title":"New Engl J Med"},{"key":"10.1016\/j.cca.2008.07.014_bib22","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0002-9149(03)00897-X","article-title":"Influence of aspirin on inflammatory markers in patients after acute myocardial infarction","volume":"92","author":"Solheim","year":"2003","journal-title":"Am J Cardiol"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989810800363X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989810800363X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T11:47:14Z","timestamp":1631533634000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000989810800363X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":22,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S000989810800363X"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2008.07.014","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}