{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:26:35Z","timestamp":1777937195270,"version":"3.51.4"},"reference-count":35,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.cca.2008.09.025","type":"journal-article","created":{"date-parts":[[2008,10,3]],"date-time":"2008-10-03T08:09:03Z","timestamp":1223021343000},"page":"102-108","source":"Crossref","is-referenced-by-count":71,"title":["Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy"],"prefix":"10.1016","volume":"399","author":[{"given":"Cong","family":"Lei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2008.09.025_bib1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.yjmcc.2004.04.010","article-title":"Cellular and molecular mechanisms of systolic and diastolic dysfunction in an avian model of dilated cardiomyopathy","volume":"37","author":"Wu","year":"2004","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.cca.2008.09.025_bib2","doi-asserted-by":"crossref","first-page":"9C","DOI":"10.1016\/0002-9149(89)90677-2","article-title":"Pathologic anatomy of the dilated cardiomyopathies","volume":"64","author":"Ferrans","year":"1989","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cca.2008.09.025_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.hlc.2006.07.013","article-title":"Nutritional deficiency of selenium secondary to weight loss (bariatric) surgery associated with life-threatening cardiomyopathy","volume":"16","author":"Boldery","year":"2007","journal-title":"Heart Lung Circ"},{"key":"10.1016\/j.cca.2008.09.025_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00644785","article-title":"Keshan disease\u2014an endemic cardiomyopathy in China","volume":"401","author":"Ge","year":"1983","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"10.1016\/j.cca.2008.09.025_bib5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0048-9697(01)00889-0","article-title":"Selenium in soil and endemic diseases in China","volume":"284","author":"Tan","year":"2002","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.cca.2008.09.025_bib6","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0046-8177(85)80110-6","article-title":"Keshan disease: an endemic cardiomyopathy in China","volume":"16","author":"Li","year":"1985","journal-title":"Human Pathol"},{"key":"10.1016\/j.cca.2008.09.025_bib7","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0046-8177(88)80275-2","article-title":"Keshan disease: an entity or not","volume":"19","author":"Yu","year":"1988","journal-title":"Human Pathol"},{"key":"10.1016\/j.cca.2008.09.025_bib8","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1161\/01.CIR.0000091084.46500.BB","article-title":"Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment","volume":"108","author":"Maack","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.09.025_bib9","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tox.2006.06.008","article-title":"Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress","volume":"226","author":"Yang","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.cca.2008.09.025_bib10","first-page":"34","article-title":"The relationship between metabolic control and the plasma total homocysteine in type 2 diabetes treated with insulin","volume":"45","author":"Yang","year":"2006","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"10.1016\/j.cca.2008.09.025_bib11","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1056\/NEJMoa030535","article-title":"Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease","volume":"349","author":"Blankenberg","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cca.2008.09.025_bib12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0009-8981(83)90062-1","article-title":"Congestive cardiomyopathy and the selenium content of serum","volume":"128","author":"Oster","year":"1983","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.cca.2008.09.025_bib13","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1096\/fasebj.12.12.1143","article-title":"Glutathione peroxidase protects mice from viral-induced myocarditis","volume":"12","author":"Beck","year":"1998","journal-title":"FASEB J"},{"key":"10.1016\/j.cca.2008.09.025_bib14","doi-asserted-by":"crossref","first-page":"22528","DOI":"10.1074\/jbc.273.35.22528","article-title":"Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide","volume":"273","author":"de Haan","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cca.2008.09.025_bib15","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1161\/01.CIR.0000109701.77059.E9","article-title":"Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice","volume":"109","author":"Shiomi","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.09.025_bib16","doi-asserted-by":"crossref","first-page":"H2237","DOI":"10.1152\/ajpheart.00427.2006","article-title":"Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart","volume":"291","author":"Matsushima","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.cca.2008.09.025_bib17","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1093\/carcin\/15.12.2769","article-title":"Loss of heterozygosity of the human cytosolic glutathione peroxidase I gene in lung cancer","volume":"15","author":"Moscow","year":"1994","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cca.2008.09.025_bib18","first-page":"3347","article-title":"Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium","volume":"63","author":"Hu","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2008.09.025_bib19","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1161\/01.CIR.0000026820.87824.6A","article-title":"Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure","volume":"106","author":"Forgione","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2008.09.025_bib20","first-page":"313","article-title":"The relationship between selenium and etiology of Keshan disease","volume":"14","author":"Yang","year":"1983","journal-title":"Sheng Li Ke Xue Jin Zhan"},{"key":"10.1016\/j.cca.2008.09.025_bib21","first-page":"1090","article-title":"Determination of arsenic and selenium in environmental and agricultural samples by hydride generation atomic absorption spectrometry","volume":"71","author":"Hershey","year":"1988","journal-title":"J Assoc Off Anal Chem"},{"key":"10.1016\/j.cca.2008.09.025_bib22","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1093\/carcin\/bgh203","article-title":"Glutathione pathway genes and lung cancer risk in young and old populations","volume":"25","author":"Yang","year":"2004","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cca.2008.09.025_bib23","doi-asserted-by":"crossref","first-page":"9535","DOI":"10.1074\/jbc.271.16.9535","article-title":"Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130\/leukemia inhibitory factor receptor-dependent pathways","volume":"271","author":"Wollert","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cca.2008.09.025_bib24","doi-asserted-by":"crossref","first-page":"11058","DOI":"10.1074\/jbc.275.15.11058","article-title":"Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells","volume":"275","author":"Faure","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cca.2008.09.025_bib25","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00019501-200304000-00007","article-title":"Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease","volume":"14","author":"Winter","year":"2003","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.cca.2008.09.025_bib26","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.2337\/diabetes.53.9.2455","article-title":"Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients","volume":"53","author":"Hamanishi","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.cca.2008.09.025_bib27","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1006\/pmed.1996.0117","article-title":"Gene\u2013environment interaction: definitions and study designs","volume":"25","author":"Ottman","year":"1996","journal-title":"Prev Med"},{"key":"10.1016\/j.cca.2008.09.025_bib28","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.freeradbiomed.2006.02.024","article-title":"Attenuation of doxorubicin-induced contractile and mitochondrial dysfunction in mouse heart by cellular glutathione peroxidase","volume":"41","author":"Xiong","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.cca.2008.09.025_bib29","first-page":"130","article-title":"Effects of oxidative DNA damage and genetic polymorphism of the glutathione peroxidase 1 (GPX1) and 8-oxoguanine glycosylase 1 (hOGG1) on lung cancer","volume":"39","author":"Lee","year":"2006","journal-title":"J Prev Med Pub Health"},{"key":"10.1016\/j.cca.2008.09.025_bib30","first-page":"6381","article-title":"Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk","volume":"60","author":"Ratnasinghe","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.cca.2008.09.025_bib31","first-page":"624","article-title":"Selenium and cardiovascular disease: selected issues","volume":"60","author":"Zagrodzki","year":"2006","journal-title":"Postepy Hig Med Dosw (Online)"},{"key":"10.1016\/j.cca.2008.09.025_bib32","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/carcin\/bgi267","article-title":"Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study","volume":"27","author":"Ravn-Haren","year":"2006","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cca.2008.09.025_bib33","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1006\/bcmd.2000.0325","article-title":"Phenotype determination of a common Pro-Leu polymorphism in human glutathione peroxidase 1","volume":"26","author":"Forsberg","year":"2000","journal-title":"Blood Cells Mol Diseases"},{"key":"10.1016\/j.cca.2008.09.025_bib34","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1158\/1055-9965.391.13.3","article-title":"DNA stability and serum selenium concentrations in a high-risk group for prostate cancer","volume":"13","author":"Karunasinghe","year":"2004","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"10.1016\/j.cca.2008.09.025_bib35","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1096\/fj.02-0752rev","article-title":"Oxidative DNA damage: mechanisms, mutation, and disease","volume":"17","author":"Cooke","year":"2003","journal-title":"FASEB J"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898108004762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898108004762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T06:25:53Z","timestamp":1684563953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898108004762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":35,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0009898108004762"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2008.09.025","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}