{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T16:01:53Z","timestamp":1771862513035,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"23-24","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Ministerio de Educaci\u00f3n y Ciencia","award":["SAF2007-61863"],"award-info":[{"award-number":["SAF2007-61863"]}]},{"name":"Plan Andaluz de Investigaci\u00f3n, Junta de Andaluc\u00eda"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.cca.2011.08.024","type":"journal-article","created":{"date-parts":[[2011,8,25]],"date-time":"2011-08-25T16:08:24Z","timestamp":1314288504000},"page":"2267-2271","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases"],"prefix":"10.1016","volume":"412","author":[{"given":"Khaoula","family":"Hamdouch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"P\u00e9rez-Venegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Astola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim J.","family":"Yen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohcine","family":"Bennani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel M.","family":"Valdivia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2011.08.024_bb0005","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1073\/pnas.77.3.1627","article-title":"Autoantibody to centromere (kinetochore) in scleroderma sera","volume":"77","author":"Moroi","year":"1980","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.cca.2011.08.024_bb0010","first-page":"27","article-title":"The clinical significance of antinuclear antibodies in connective tissue diseases","volume":"2","author":"Van Venrooij","year":"1991","journal-title":"Semin Clin Immunol"},{"key":"10.1016\/j.cca.2011.08.024_bb0015","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0889-857X(21)00738-9","article-title":"Autoantibodies in scleroderma","volume":"18","author":"Rothfield","year":"1992","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.cca.2011.08.024_bb0020","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/BF00328227","article-title":"Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma","volume":"91","author":"Earnshaw","year":"1985","journal-title":"Chromosoma"},{"key":"10.1016\/j.cca.2011.08.024_bb0025","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/cm.970260305","article-title":"CENPF is a ca 400kDa kinetochore protein that exhibits a cell-cycle dependent localization","volume":"26","author":"Rattner","year":"1993","journal-title":"Cell Motil Cytoskeleton"},{"key":"10.1016\/j.cca.2011.08.024_bb0030","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1002\/art.1780390813","article-title":"The centromere kinesin-like protein CENPE. An autoantigen in systemic sclerosis","volume":"39","author":"Rattner","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.cca.2011.08.024_bb0035","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s00296-004-0568-4","article-title":"Anti CENPH antibodies in patients with Sjogren's syndrome","volume":"26","author":"Hsu","year":"2006","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.cca.2011.08.024_bb0040","doi-asserted-by":"crossref","first-page":"781","DOI":"10.3899\/jrheum.080726","article-title":"CENPO a protein localized at the centromere throughout the cell cycle is a novel target antigen in systemic sclerosis","volume":"36","author":"Saito","year":"2009","journal-title":"J Rheumatol"},{"key":"10.1016\/j.cca.2011.08.024_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1740-2557-4-1","article-title":"Autoantibodies against the chromosomal passenger protein INCENP found in a patient with Graham Little-Piccardi-Lassueur syndrome","volume":"4","author":"Rodr\u00edguez-Bayona","year":"2007","journal-title":"J Autoimmun Dis"},{"key":"10.1016\/j.cca.2011.08.024_bb0050","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev.iy.11.040193.000455","article-title":"The role of autoantibodies in autoimmune disease","volume":"11","author":"Naparstek","year":"1993","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.cca.2011.08.024_bb0055","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/ncb1396","article-title":"The CENPH-I complex is required for the efficient incorporation of newly synthesized CENPA into centromeres","volume":"5","author":"Okada","year":"2006","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.cca.2011.08.024_bb0060","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/ng0497-345","article-title":"Formation of de novo centromeres and construction of first-generation human artificial microchromosomes","volume":"15","author":"Harrington","year":"1997","journal-title":"Nat Genet"},{"key":"10.1016\/j.cca.2011.08.024_bb0065","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/ncb953","article-title":"Human CENPI specifies localization of CENPF, MAD1, and MAD2 to kinetochores and is essential for mitosis","volume":"5","author":"Liu","year":"2003","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.cca.2011.08.024_bb0070","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000133502","article-title":"Anticentromere antibody specific to human cells directed against the CENPB autoantigen","volume":"63","author":"Bejarano","year":"1993","journal-title":"Cytogenet Cell Genet"},{"key":"10.1016\/j.cca.2011.08.024_bb0075","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/art.1780370214","article-title":"Anticentromere autoantibodies: evaluation of an ELISA using recombinant fusion protein CENPB as antigen","volume":"37","author":"Vazquez-Abad","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.cca.2011.08.024_bb0080","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/rheumatology\/34.5.407","article-title":"Frequency of autoantibodies to a major epitope on the carboxyl terminal fragment of CENPB in patients with autoimmune disease","volume":"34","author":"Whyte","year":"1995","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.cca.2011.08.024_bb0085","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/j.cgh.2009.07.012","article-title":"Value of autoantibody analysis in the differential diagnosis of chronic cholestatic liver disease","volume":"7","author":"Milkiewicz","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cca.2011.08.024_bb0090","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/art.1780340111","article-title":"Prognostic significance of anticentromere antibodies and anti-topoisomerase I antibodies in Raynaud's disease: a prospective study","volume":"34","author":"Weiner","year":"1991","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.cca.2011.08.024_bb0095","doi-asserted-by":"crossref","first-page":"4979","DOI":"10.1073\/pnas.84.14.4979","article-title":"Analysis of anticentromere autoantibodies using cloned autoantigen CENPB","volume":"84","author":"Earnshaw","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.cca.2011.08.024_bb0100","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/1529-0131(199904)42:3<455::AID-ANR10>3.0.CO;2-3","article-title":"A critical evaluation of enzyme immuno-assays for detection of antinuclear autoantibodies of defined specificities. I Precision, sensitivity and specificity","volume":"42","author":"Tan","year":"1999","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.cca.2011.08.024_bb0105","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.dld.2009.01.014","article-title":"Is prevalence of PBC underestimated in patients with systemic sclerosis?","volume":"41","author":"Norman","year":"2009","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.cca.2011.08.024_bb0110","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10354-007-0451-5","article-title":"Autoantibodies in systemic sclerosis (scleroderma): clues for clinical evaluation prognosis and pathogenesis","volume":"158","author":"Grassegger","year":"2008","journal-title":"Wien Med Wochenschr"},{"key":"10.1016\/j.cca.2011.08.024_bb0115","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1136\/gut.2003.023937","article-title":"Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort","volume":"53","author":"Prince","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.cca.2011.08.024_bb0120","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.3899\/jrheum.090340","article-title":"Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abnormalities in a large population of systemic sclerosis patients","volume":"36","author":"Assassi","year":"2009","journal-title":"J Rheumatol"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898111004724?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898111004724?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T20:00:58Z","timestamp":1762113658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898111004724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":24,"journal-issue":{"issue":"23-24","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0009898111004724"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2011.08.024","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2011.08.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}