{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T16:36:20Z","timestamp":1770914180213,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.cca.2014.07.018","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T13:01:15Z","timestamp":1406120475000},"page":"136-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Matrix metalloproteinases and left ventricular function and structure in spinal cord injured subjects"],"prefix":"10.1016","volume":"437","author":[{"given":"Roberto","family":"Schreiber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Layde R.","family":"Paim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme","family":"de Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 R.","family":"Matos-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anselmo de A.","family":"Costa e Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane M.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariane","family":"Borges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliza R.","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina C.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 I.","family":"Gorla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Alberto","family":"Cliquet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Wilson","family":"Nadruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2014.07.018_bb0005","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1093\/eurheartj\/ehm037","article-title":"How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology","volume":"28","author":"Paulus","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cca.2014.07.018_bb0010","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.atherosclerosis.2008.04.013","article-title":"Carotid intima\u2013media thickness is increased in patients with spinal cord injury independent of traditional cardiovascular risk factors","volume":"202","author":"Matos-Souza","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.cca.2014.07.018_bb0015","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/sc.2010.88","article-title":"Altered left ventricular diastolic function in spinal cord injury subjects","volume":"49","author":"Matos-Souza","year":"2011","journal-title":"Spinal Cord"},{"key":"10.1016\/j.cca.2014.07.018_bb0020","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1212\/WNL.0b013e3182a1aa68","article-title":"Cardiovascular disease and spinal cord injury: results from a national population health survey","volume":"81","author":"Cragg","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.cca.2014.07.018_bb0025","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1179\/2045772313Y.0000000161","article-title":"Structural and functional left ventricular impairment in subjects with chronic spinal cord injury and no overt cardiovascular disease","volume":"37","author":"Driussi","year":"2014","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.cca.2014.07.018_bb0030","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1249\/MSS.0000000000000187","article-title":"Physical activity and improved diastolic function in spinal cord-injured subjects","volume":"46","author":"de Rossi","year":"2014","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.cca.2014.07.018_bb0035","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0002-9440(10)62228-6","article-title":"Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice","volume":"166","author":"Heymans","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1016\/j.cca.2014.07.018_bb0040","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1161\/01.HYP.0000208840.30778.00","article-title":"Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload","volume":"47","author":"Matsusaka","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.cca.2014.07.018_bb0045","first-page":"335","article-title":"Inhibition of matrix metalloproteinases (MMPs) as a potential strategy to ameliorate hypertension-induced cardiovascular alterations","volume":"14","author":"Castro","year":"2013","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.cca.2014.07.018_bb0050","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1161\/01.CIR.0000129318.79570.84","article-title":"Relations of plasma matrix metalloproteinase-9 to clinical cardiovascular risk factors and echocardiographic left ventricular measures: the Framingham Heart Study","volume":"109","author":"Sundstr\u00f6m","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2014.07.018_bb0055","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1161\/CIRCULATIONAHA.105.573865","article-title":"Matrix metalloproteinases\/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease","volume":"113","author":"Ahmed","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2014.07.018_bb0060","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1161\/CIRCHEARTFAILURE.110.958199","article-title":"Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure","volume":"4","author":"Zile","year":"2011","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.cca.2014.07.018_bb0065","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1042\/CS20080278","article-title":"Role of matrix metalloproteinases and their tissue inhibitors as potential biomarkers of left ventricular remodelling in the athlete's heart","volume":"117","author":"Vianello","year":"2009","journal-title":"Clin Sci"},{"key":"10.1016\/j.cca.2014.07.018_bb0070","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.cca.2014.07.018_bb0075","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1152\/physrev.00012.2007","article-title":"Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function","volume":"87","author":"Spinale","year":"2007","journal-title":"Physiol Rev"},{"key":"10.1016\/j.cca.2014.07.018_bb0080","doi-asserted-by":"crossref","first-page":"877","DOI":"10.3945\/jn.110.135921","article-title":"Sodium intake is associated with carotid artery structure alterations and plasma matrix metalloproteinase-9 upregulation in hypertensive adults","volume":"141","author":"Ferreira-Sae","year":"2011","journal-title":"J Nutr"},{"key":"10.1016\/j.cca.2014.07.018_bb0085","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.cca.2008.04.008","article-title":"Inverse relationship between markers of nitric oxide formation and plasma matrix metalloproteinase-9 levels in healthy volunteers","volume":"394","author":"Demacq","year":"2008","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.cca.2014.07.018_bb0090","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1016\/j.cca.2010.08.008","article-title":"Matrix metalloproteinase 9 gene haplotypes affect left ventricular hypertrophy in hypertensive patients","volume":"411","author":"Lacchini","year":"2010","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.cca.2014.07.018_bb0095","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.euje.2005.12.014","article-title":"Recommendations for chamber quantification","volume":"7","author":"Lang","year":"2006","journal-title":"Eur J Echocardiogr"},{"key":"10.1016\/j.cca.2014.07.018_bb0100","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.cca.2011.12.021","article-title":"Circulating matrix metalloproteinases and their inhibitors in hypertension","volume":"413","author":"Fontana","year":"2012","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.cca.2014.07.018_bb0105","doi-asserted-by":"crossref","first-page":"e71280","DOI":"10.1371\/journal.pone.0071280","article-title":"Serum MMP-8: a novel indicator of left ventricular remodeling and cardiac outcome in patients after acute myocardial infarction","volume":"8","author":"Fertin","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cca.2014.07.018_bb0110","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1139\/y2012-097","article-title":"Endurance exercise in a rat model of metabolic syndrome","volume":"90","author":"Cameron","year":"2012","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.cca.2014.07.018_bb0115","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1186\/1479-5876-11-283","article-title":"The involvement of MMP-2 and MMP-9 in heart exercise-related angiogenesis","volume":"11","author":"Bellafiore","year":"2013","journal-title":"J Transl Med"},{"key":"10.1016\/j.cca.2014.07.018_bb0120","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1161\/CIRCULATIONAHA.106.638569","article-title":"Diastolic heart failure. evidence of increased myocardial collagen turnover linked to diastolic dysfunction","volume":"115","author":"Martos","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.cca.2014.07.018_bb0125","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.jacc.2004.07.023","article-title":"Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression","volume":"44","author":"Polyakova","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cca.2014.07.018_bb0130","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1476-5381.2012.01917.x","article-title":"The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases","volume":"166","author":"Rietz","year":"2012","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.cca.2014.07.018_bb0135","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/PHM.0b013e31802f0247","article-title":"Cardiovascular disease in spinal cord injury: an overview of prevalence, risk, evaluation, and management","volume":"86","author":"Myers","year":"2007","journal-title":"Am J Phys Med Rehabil"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898114003052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898114003052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T14:45:42Z","timestamp":1757861142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898114003052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":27,"alternative-id":["S0009898114003052"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2014.07.018","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Matrix metalloproteinases and left ventricular function and structure in spinal cord injured subjects","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2014.07.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}