{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:15:24Z","timestamp":1785147324591,"version":"3.55.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T00:00:00Z","timestamp":1563494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.cca.2019.07.015","type":"journal-article","created":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T06:55:38Z","timestamp":1563173738000},"page":"48-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Hybrid panel of biomarkers can be useful in the diagnosis of pleural and peritoneal effusions"],"prefix":"10.1016","volume":"497","author":[{"given":"Daniel K.","family":"Faria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S.","family":"Faria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitria","family":"Doi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena M.P.","family":"Acencio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8634-5100","authenticated-orcid":false,"given":"Leila","family":"Antonangelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2019.07.015_bb0005","first-page":"17","article-title":"New biochemical parameters in the differential diagnosis of ascitic fluids","volume":"9","author":"Angeleri","year":"2016","journal-title":"Gastroenterology."},{"key":"10.1016\/j.cca.2019.07.015_bb0010","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.clinbiochem.2013.02.010","article-title":"CEA, AFP and CA 19-9 analysis in peritoneal fluid to differentiate causes of ascites formation","volume":"46","author":"Kaleta","year":"2013","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.cca.2019.07.015_bb0015","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1159\/000112221","article-title":"Diagnostic work-up of pleural effusions","volume":"75","author":"Froudarakis","year":"2008","journal-title":"Respiration."},{"key":"10.1016\/j.cca.2019.07.015_bb0020","article-title":"Live-single-cell phenotypic cancer biomarkers-future role in precision oncology?","volume":"21","author":"Sant","year":"2017","journal-title":"Nature Partiness Jornal Precision Oncology."},{"key":"10.1016\/j.cca.2019.07.015_bb0025","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s13277-011-0275-1","article-title":"Utility of serum tumor markers as an aid in the differential diagnosis of patients with clinical suspicion of cancer and in patients with cancer of unknown primary site","volume":"33","author":"Molina","year":"2012","journal-title":"Tumour Biol."},{"key":"10.1016\/j.cca.2019.07.015_bb0030","first-page":"27","article-title":"Differentiating tuberculous from malignant pleural effusions: a scoring model","volume":"5","author":"Porcel","year":"2003","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.cca.2019.07.015_bb0035","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/abbs\/gmx147","article-title":"Correlation between circulating endothelial progenitor cells and serum carcinoembryonic antigen concentration in colorectal cancer","volume":"50","author":"Li","year":"2018","journal-title":"Acta Biochim. Biophys. Sin."},{"key":"10.1016\/j.cca.2019.07.015_bb0040","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3747\/co.22.2563","article-title":"Pleural fluid tumour markers in malignant pleural effusion with inconclusive cytologic results","volume":"22","author":"Antonangelo","year":"2015","journal-title":"Curr. Oncol."},{"key":"10.1016\/j.cca.2019.07.015_bb0045","doi-asserted-by":"crossref","first-page":"363","DOI":"10.7314\/APJCP.2014.15.1.363","article-title":"CA125, CA153 and CA199 in malignant pleural effusions predict the cause","volume":"61","author":"Wang","year":"2014","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"10.1016\/j.cca.2019.07.015_bb0050","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1080\/00325481.2017.1331112","article-title":"Diagnostic performance of CTLA-4, carcinoembryonic antigen and CYFRA 21-1 for malignant pleural effusion","volume":"129","author":"Chen","year":"2017","journal-title":"Postgrad. Med."},{"key":"10.1016\/j.cca.2019.07.015_bb0055","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ccell.2017.10.003","article-title":"An HIF-1\u03b1\/VEGF-A axis in cytotoxic T cells regulates tumor progression","volume":"13","author":"Palazon","year":"2017","journal-title":"Cancer Cell"},{"key":"10.1016\/j.cca.2019.07.015_bb0060","first-page":"1","article-title":"Systematic review and meta-analysis of vascular endothelial growth factor as a biomarker for malignant pleural effusions","author":"Fafliora","year":"2016","journal-title":"Phys. Rep."},{"key":"10.1016\/j.cca.2019.07.015_bb0065","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/nri2326","article-title":"Inhibitory B7-family molecules in the tumour microenvironment","volume":"8","author":"Zou","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cca.2019.07.015_bb0070","doi-asserted-by":"crossref","first-page":"4156","DOI":"10.4049\/jimmunol.171.8.4156","article-title":"Blockade of B7-H1 suppresses the development of chronic intestinal inflammation","volume":"171","author":"Kanai","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.cca.2019.07.015_bb0075","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/2049-6958-9-49","article-title":"A novel biomarker in the diagnosis of parapneumonic effusion: neutrophil gelatinase-associated lipocalin","volume":"9","author":"G\u00fcm\u00fcs","year":"2014","journal-title":"Multidiscip Respir Med."},{"key":"10.1016\/j.cca.2019.07.015_bb0080","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1053\/j.ajkd.2008.01.020","article-title":"Neutrophil gelatinase-associated lipocalin (NGAL) as a marker of kidney damage","volume":"52","author":"Bolignano","year":"2008","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.cca.2019.07.015_bb0085","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.18632\/oncotarget.1738","article-title":"Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer","volume":"5","author":"Candido","year":"2014","journal-title":"Oncotarget."},{"key":"10.1016\/j.cca.2019.07.015_bb0090","doi-asserted-by":"crossref","first-page":"4026","DOI":"10.1038\/s41598-017-04189-4","article-title":"Proteome profiling reveals novel biomarkers to identify complicated parapneumonic effusions","volume":"7","author":"Wu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cca.2019.07.015_bb0095","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jbior.2018.05.002","article-title":"Roles of p53, NF-\u03baB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines","volume":"69","author":"Chappell","year":"2018","journal-title":"Adv Biol Regul."},{"key":"10.1016\/j.cca.2019.07.015_bb0100","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cca.2012.12.020","article-title":"Assessment of neutrophil gelatinase-associated lipocalin and lactate dehydrogenase in peritoneal fluids for the screening of bacterial peritonitis","volume":"418","author":"Lippi","year":"2013","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cca.2019.07.015_bb0105","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1038\/bjc.2012.478","article-title":"Calprotectin: a novel biomarker for the diagnosis of pleural effusion","volume":"107","author":"S\u00e1nchez-Otero","year":"2012","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.cca.2019.07.015_bb0110","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1177\/0022034518756330","article-title":"Calprotectin and the initiation and progression of head and neck cancer","volume":"97","author":"Argyris","year":"2018","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.cca.2019.07.015_bb0115","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s00005-017-0499-x","article-title":"Soluble TREM-1 serum concentration can early predict mortality of patients with sepsis, severe sepsis and septic shock","volume":"66","author":"Jedynak","year":"2018","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.cca.2019.07.015_bb0120","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ccc.2010.12.006","article-title":"Triggering receptor expressed on myeloid cell 1","volume":"27","author":"Barraud","year":"2011","journal-title":"Crit. Care Clin."},{"issue":"12","key":"10.1016\/j.cca.2019.07.015_bb0125","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1517\/13543776.2014.977865","article-title":"Triggering receptor expressed on myeloid cells receptor family modulators: a patent review","author":"Pelham","year":"2014","journal-title":"Expert Opin Ther Pat."},{"key":"10.1016\/j.cca.2019.07.015_bb0130","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1378\/chest.99.3.623","article-title":"Serum adenosine deaminase in viral and bacterial pneumonia","volume":"99","author":"Klockars","year":"1991","journal-title":"Chest."},{"key":"10.1016\/j.cca.2019.07.015_bb0135","first-page":"81128","article-title":"Predictive models for diagnosis of pleural effusions secondary to tuberculosis or cancer","volume":"8","author":"Sales","year":"2009","journal-title":"Respirology."},{"issue":"3","key":"10.1016\/j.cca.2019.07.015_bb0140","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0192-0561(92)90171-G","article-title":"The structure and function of interferon-gamma receptors","author":"Schreiber","year":"1992","journal-title":"Int. J. Immunopharmacol."},{"key":"10.1016\/j.cca.2019.07.015_bb0145","first-page":"475","article-title":"IFN\u03b3\/TNF\u03b1 specific-cells and effector memory phenotype associate with active tuberculosis","volume":"66","author":"Petruccioli","year":"2013","journal-title":"J. Inf. Secur."},{"issue":"9","key":"10.1016\/j.cca.2019.07.015_bb0150","doi-asserted-by":"crossref","first-page":"E336","DOI":"10.3390\/cancers10090336","article-title":"Revisiting Neutrophil Gelatinase-Associated Lipocalin (NGAL) in cancer: saint or sinner?","volume":"10","author":"Bauvois","year":"2018","journal-title":"Cancers (Basel)"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898119319527?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898119319527?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T14:48:44Z","timestamp":1757861324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898119319527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":30,"alternative-id":["S0009898119319527"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2019.07.015","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hybrid panel of biomarkers can be useful in the diagnosis of pleural and peritoneal effusions","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2019.07.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}