{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T03:55:37Z","timestamp":1788062137031,"version":"build-2784847793"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100017962","name":"Jiangsu Commission of Health","doi-asserted-by":"publisher","award":["H2018076"],"award-info":[{"award-number":["H2018076"]}],"id":[{"id":"10.13039\/100017962","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.cca.2020.05.003","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T22:12:44Z","timestamp":1588630364000},"page":"224-227","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Is testing of aspartate aminotransferase necessary along with every alanine aminotransferase for health check in elderly individuals?"],"prefix":"10.1016","volume":"507","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0662-1302","authenticated-orcid":false,"given":"Guo-Ming","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao-Ming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Fan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2020.05.003_b0005","unstructured":"http:\/\/www.nhfpc.gov.cn\/jws\/s3578\/201703\/d20c37e23e1f4c7db7b8e25f34473e1b.shtml\/. Accessed Jan 20, 2019."},{"key":"10.1016\/j.cca.2020.05.003_b0010","first-page":"2223","article-title":"Special considerations in interpreting liver function tests","volume":"59","author":"Johnston","year":"1999","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.cca.2020.05.003_b0015","unstructured":"http:\/\/www.nhc.gov.cn\/ewebeditor\/uploadfile\/2013\/01\/20130109170719547.pdf\/. Accessed Jan 20, 2019."},{"key":"10.1016\/j.cca.2020.05.003_b0020","unstructured":"https:\/\/www.medcalc.org\/. Accessed Jan 20, 2019."},{"key":"10.1016\/j.cca.2020.05.003_b0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.clinbiochem.2018.11.012","article-title":"RDW, NLR and RLR in predicting liver failure and prognosis in patients with hepatitis E virus infection","volume":"63","author":"Jian","year":"2019","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.cca.2020.05.003_b0030","unstructured":"https:\/\/www.medcalc.org\/manual\/testsfornormaldistribution.php\/. Accessed Jan 20, 2019."},{"key":"10.1016\/j.cca.2020.05.003_b0035","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1093\/clinchem\/46.12.2027","article-title":"Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests","volume":"46","author":"Dufour","year":"2000","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cca.2020.05.003_b0040","unstructured":"Chinese Society of Hepatology of Chinese Medical Association Chinese Society of Gastroenterology of Chinese Medical Association. Consensus on the clinical significance and evaluation of common liver biochemistry tests. Chinese J. Hepatol., 18 (5) (201) 387\u2013393."},{"issue":"3","key":"10.1016\/j.cca.2020.05.003_b0045","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1309\/AJCPO47VAWYRIDHG","article-title":"Limiting the testing of AST: a diagnostically nonspecific enzyme","volume":"144","author":"Xu","year":"2015","journal-title":"Am. J. Clin. Pathol."},{"issue":"4","key":"10.1016\/j.cca.2020.05.003_b0050","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/ajcp\/aqw069","article-title":"Limiting the Testing of Aspartate Aminotransferase: Using the Proper Upper Limit of the Reference Interval of Alanine Aminotransferase","volume":"145","author":"Zhang","year":"2016","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.cca.2020.05.003_b0055","first-page":"166","article-title":"Prediction and analysis of the number of the elderly population in China","volume":"24","author":"Wei","year":"2019","journal-title":"Co-Operative Econ. Sci."},{"key":"10.1016\/j.cca.2020.05.003_b0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.clinbiochem.2018.12.003","article-title":"The potential of reducing AST testing in hospital settings","volume":"64","author":"Josko","year":"2019","journal-title":"Clin. Biochem."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989812030200X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989812030200X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T14:55:10Z","timestamp":1757861710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000989812030200X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":12,"alternative-id":["S000989812030200X"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2020.05.003","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is testing of aspartate aminotransferase necessary along with every alanine aminotransferase for health check in elderly individuals?","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2020.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}