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Gastroenterol."},{"issue":"6","key":"10.1016\/j.cca.2021.03.002_b0690","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1002\/hep.25930","article-title":"Liver vitamin D receptor, CYP2R1, and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with nonalcoholic steatohepatitis or hepatitis C virus","volume":"56","author":"Barchetta","year":"2012","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.cca.2021.03.002_b0695","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/liv.12106","article-title":"Vitamin D in chronic liver disease","volume":"33","author":"Stokes","year":"2013","journal-title":"Liver Int"},{"issue":"1","key":"10.1016\/j.cca.2021.03.002_b0700","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S1665-2681(19)30806-3","article-title":"Factors associated with 25-hydroxyvitamin D levels in patients with liver cirrhosis","volume":"14","author":"Costa Silva","year":"2015","journal-title":"Ann. 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Chem."},{"issue":"7","key":"10.1016\/j.cca.2021.03.002_b0735","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/ki.2010.543","article-title":"Defective renal maintenance of the vitamin D endocrine system impairs vitamin D renoprotection: a downward spiral in kidney disease","volume":"79","author":"Dusso","year":"2011","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.cca.2021.03.002_b0740","doi-asserted-by":"crossref","DOI":"10.3390\/nu9040328","article-title":"Vitamin D in chronic kidney disease and dialysis patients","volume":"9","author":"Jean","year":"2017","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.cca.2021.03.002_b0745","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1053\/j.jrn.2014.04.005","article-title":"G. 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Nutr."},{"issue":"7","key":"10.1016\/j.cca.2021.03.002_b1465","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1017\/S0007114514001883","article-title":"Impact of pregnancy on vitamin D status: a longitudinal study","volume":"112","author":"Zhang","year":"2014","journal-title":"Br. J. Nutr."},{"issue":"9","key":"10.1016\/j.cca.2021.03.002_b1470","doi-asserted-by":"crossref","first-page":"3470","DOI":"10.3390\/nu5093470","article-title":"Increased plasma concentrations of vitamin D metabolites and vitamin D binding protein in women using hormonal contraceptives: a cross-sectional study","volume":"5","author":"Moller","year":"2013","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.cca.2021.03.002_b1475","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4158\/EP161604.RA","article-title":"Vitamin D binding protein and 25-hydroxyvitamin D levels: emerging clinical applications","volume":"23","author":"Jassil","year":"2017","journal-title":"Endocr. 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Significance of the free 1,25-dihydroxyvitamin D3 concentration","volume":"67","author":"Bouillon","year":"1981","journal-title":"J. Clin. Invest."},{"issue":"6","key":"10.1016\/j.cca.2021.03.002_b1505","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1002\/jbmr.2871","article-title":"Free or Total 25OHD as marker for vitamin D status?","volume":"31","author":"Bouillon","year":"2016","journal-title":"J. Bone Miner. Res."},{"issue":"3","key":"10.1016\/j.cca.2021.03.002_b1510","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/clinchem\/40.3.435","article-title":"Simple method for determining specific binding capacity of vitamin D-binding protein and its use to calculate the concentration of \u201cfree\u201d 1,25-dihydroxyvitamin D","volume":"40","author":"Vieth","year":"1994","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cca.2021.03.002_b1515","unstructured":"R.F. Chun, C.M. Nielson, Free vitamin D: concepts, assays, outcomes and prospects, in: D. Feldman, J. 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