{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T20:34:55Z","timestamp":1790973295191,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.cca.2022.02.005","type":"journal-article","created":{"date-parts":[[2022,2,12]],"date-time":"2022-02-12T10:39:43Z","timestamp":1644662383000},"page":"21-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Large-scale retrospective analyses of the effect of iron deficiency anemia on hemoglobin A1c concentrations"],"prefix":"10.1016","volume":"529","author":[{"given":"Lokinendi V.","family":"Rao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George W.","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caixia","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin H.","family":"Kroll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2022.02.005_b0005","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4137\/BMI.S38440","article-title":"Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients","volume":"11","author":"Sherwani","year":"2016","journal-title":"Biomark Insights."},{"issue":"Suppl_1","key":"10.1016\/j.cca.2022.02.005_b0010","first-page":"S14","volume":"43","year":"2020","journal-title":"Diabetes Care."},{"key":"10.1016\/j.cca.2022.02.005_b0015","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/nyas.14092","article-title":"Anemia epidemiology, pathophysiology, and etiology in low-and middle-income countries","volume":"1450","author":"Chaparro","year":"2019","journal-title":"Ann N Y Acad Sci."},{"issue":"6","key":"10.1016\/j.cca.2022.02.005_b0020","article-title":"The Effect of Anemia and the Goal of Optimal HbA1c Control in Diabetes and Non-Diabetes","volume":"12","author":"Katwal","year":"2020","journal-title":"Cureus"},{"key":"10.1016\/j.cca.2022.02.005_b0025","unstructured":"A.L. Christy, A, P.A. Manjrekar, R.P. Babu, A. Hegde, M.S. Rukmini, Influence of iron deficiency anemia on hemoglobin A1c concentrations in diabetic individuals with controlled plasma glucose concentrations. Iran Biomed J, 2014, 18(2), 88-93. doi:10.6091\/ibj.1257.2014."},{"key":"10.1016\/j.cca.2022.02.005_b0030","doi-asserted-by":"crossref","unstructured":"W. Guo, W, Q. Zhou, Y. Jia, J. Xu, Increased Concentrations of Glycated Hemoglobin A1c and Iron Deficiency Anemia: A Review. Med Sci Monit, 2019, 25, 8371-8378. doi:10.12659\/MSM.916719.","DOI":"10.12659\/MSM.916719"},{"issue":"4","key":"10.1016\/j.cca.2022.02.005_b0035","doi-asserted-by":"crossref","first-page":"539","DOI":"10.4093\/dmj.2018.0072","article-title":"Glycosylated Hemoglobin in Subjects Affected by Iron-Deficiency Anemia","volume":"43","author":"Intra","year":"2019","journal-title":"Diabetes Metab J"},{"issue":"1\u20132","key":"10.1016\/j.cca.2022.02.005_b0040","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.clinbiochem.2015.09.004","article-title":"Effect of iron deficiency anemia on HbA1c concentrations is dependent on the degree of anemia","volume":"49","author":"Silva","year":"2016","journal-title":"Clin Biochem"},{"issue":"7","key":"10.1016\/j.cca.2022.02.005_b0045","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1007\/s00125-015-3599-3","article-title":"The effect of anemia and abnormalities of erythrocyte indices on HbA1c analysis: a systematic review","volume":"58","author":"English","year":"2015","journal-title":"Diabetologia."},{"issue":"3","key":"10.1016\/j.cca.2022.02.005_b0050","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1159\/000079722","article-title":"Effect of iron deficiency anemia on the concentrations of hemoglobin A1c in nondiabetic patients","volume":"112","author":"Coban","year":"2004","journal-title":"Acta Hematol."},{"issue":"5","key":"10.1016\/j.cca.2022.02.005_b0055","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4093\/dmj.2013.37.5.343","article-title":"Hemoglobin a1c may be an inadequate diagnostic tool for diabetes mellitus in anemic subjects","volume":"37","author":"Son","year":"2013","journal-title":"Diabetes Metab J."},{"key":"10.1016\/j.cca.2022.02.005_b0060","doi-asserted-by":"crossref","unstructured":"S.V. Madhu, A. Raj, S. Gupta, S. Giri, U. Rusia U. Effect of iron deficiency anemia and iron supplementation on HbA1c concentrations - Implications for diagnosis of prediabetes and diabetes mellitus in Asian Indians. Clin Chim Acta. 2017 May;468:225-229. doi: 10.1016\/j.cca.2016.10.003. Epub 2016 Oct 5. PMID: 27717800.","DOI":"10.1016\/j.cca.2016.10.003"},{"issue":"2","key":"10.1016\/j.cca.2022.02.005_b0065","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.dsx.2013.02.004","article-title":"HbA1c and iron deficiency: a review","volume":"7","author":"Ahmad","year":"2013","journal-title":"Diabetes Metab Syndr"},{"issue":"6","key":"10.1016\/j.cca.2022.02.005_b0070","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.dsx.2018.06.024","article-title":"Influence of iron deficiency on Hb A1c concentrations in type 2 diabetic patients","volume":"12","author":"Urrechaga","year":"2018","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.cca.2022.02.005_b0075","doi-asserted-by":"crossref","unstructured":"A. Solomon, M. Hussein, M. Negash, A. Ahmed, F. Bekele, D. Kahase, Effect of iron deficiency anemia on HbA1c in diabetic patients at Tikur Anbessa specialized teaching hospital, Addis Ababa Ethiopia. BMC Hematol, 2019, 19, 2. doi:10.1186\/s12878-018-0132-1.","DOI":"10.1186\/s12878-018-0132-1"},{"key":"10.1016\/j.cca.2022.02.005_b0080","article-title":"HbA1c concentration decreases in iron deficiency anemia","author":"Altutas","year":"2020","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.cca.2022.02.005_b0085","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.18203\/2349-3933.ijam20192586","article-title":"A study on influence of iron deficiency anemia over HbA1c concentrations","volume":"6","author":"Kalairajan","year":"2019","journal-title":"Int J Adv Med."},{"issue":"9","key":"10.1016\/j.cca.2022.02.005_b0090","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1080\/10715760802459879","article-title":"Iron-deficiency anemia enhances red blood cell oxidative stress","volume":"42","author":"Nagababu","year":"2008","journal-title":"Free Radic Res."},{"issue":"2","key":"10.1016\/j.cca.2022.02.005_b0095","first-page":"82","article-title":"Antioxidant enzymes and oxidative stress in the erythrocytes of iron deficiency anemic patients supplemented with vitamins","volume":"18","author":"Madhikarmi","year":"2014","journal-title":"Iran Biomed J."},{"issue":"10","key":"10.1016\/j.cca.2022.02.005_b0100","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.biopha.2007.06.013","article-title":"Increased plasma malondialdehyde and fructosamine in iron deficiency anemia: Effect of treatment","volume":"61","author":"Sundaram","year":"2007","journal-title":"Biomed. Pharmacother."},{"issue":"1\u20132","key":"10.1016\/j.cca.2022.02.005_b0105","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.cca.2005.10.002","article-title":"Effect of lipid peroxides and antioxidants on glycation of hemoglobin: an in vitro study on human erythrocytes","volume":"366","author":"Selvaraj","year":"2006","journal-title":"Clin Chim Acta."},{"key":"10.1016\/j.cca.2022.02.005_b0110","doi-asserted-by":"crossref","unstructured":"R.M. Cohen, R.S. Franco, P.K. Khera, E.P. Smith, C.J. Lindsell, P.J. Ciraolo, M.B. palscak, C.H. Joiner, Red cell life span heterogeneity in hematologically normal people is sufficient to alter HbA1c. Blood 112(10) (2008) 4284-4291. doi:10.1182\/blood-2008-04-154112.","DOI":"10.1182\/blood-2008-04-154112"},{"key":"10.1016\/j.cca.2022.02.005_b0115","doi-asserted-by":"crossref","unstructured":"A.P Brooks, J. Metclafe, J.L. Day, M.S. Edwards, Iron deficiency and glycosylated hemoglobin A1c, Lancer 1980: 19 (ii):141.","DOI":"10.1016\/S0140-6736(80)90019-7"},{"issue":"1","key":"10.1016\/j.cca.2022.02.005_b0120","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1753-0407.2010.00100.x","article-title":"Iron-deficiency anemia, non-iron-deficiency anemia and HbA1c among adults in the US","volume":"3","author":"Ford","year":"2011","journal-title":"J Diabetes."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898122000559?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898122000559?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:02:19Z","timestamp":1757862139000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898122000559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":24,"alternative-id":["S0009898122000559"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2022.02.005","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Large-scale retrospective analyses of the effect of iron deficiency anemia on hemoglobin A1c concentrations","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2022.02.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}