{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T08:23:21Z","timestamp":1791620601957,"version":"4.3.4"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.cca.2023.117397","type":"journal-article","created":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T20:18:27Z","timestamp":1685391507000},"page":"117397","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Recommended reference intervals for copper and zinc in serum using the US National Health and Nutrition Examination surveys (NHANES) data"],"prefix":"10.1016","volume":"546","author":[{"given":"Duncan","family":"Andrew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robertson","family":"Gail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bramwell","family":"Morag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja","family":"Kishor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2023.117397_b0005","doi-asserted-by":"crossref","unstructured":"Recommendation for the review of biological reference intervals in medical laboratories. https:\/\/doi.org\/10.1515\/cclm-2016-0793. (2016, accessed 7th December, 2022).","DOI":"10.1515\/cclm-2016-0793"},{"key":"10.1016\/j.cca.2023.117397_b0010","unstructured":"Clinical Laboratory Standards Institute. Defining, establishing, and verifying reference intervals in the clinical laboratory: Approved guideline \u2013 third edition. https:\/\/clsi.org\/media\/1421\/ep28a3c_sample.pdf (2010, accessed 9th December, 2022)."},{"key":"10.1016\/j.cca.2023.117397_b0015","unstructured":"NHANES Questionnaires, Datasets, and Related Documentation. wwwn.cdc.gov\/nchs\/nhanes\/Default.aspx (2019, accessed 30th March, 2021)."},{"key":"10.1016\/j.cca.2023.117397_b0020","unstructured":"Desirable biological variation databases specifications. www.westgard.com\/biodatabase1.htm. (2022, accessed 4th Jan 2023)."},{"issue":"6","key":"10.1016\/j.cca.2023.117397_b0025","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1365-2230.1982.tb02488.x","article-title":"Clinical significance of diurnal variation in the estimation of plasma zinc","volume":"7","author":"McMILLAN","year":"1982","journal-title":"Clin Exp Dermatol."},{"key":"10.1016\/j.cca.2023.117397_b0030","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/ajcn\/78.4.756","article-title":"Suggested lower cutoffs of serum zinc concentrations for assessing zinc status: reanalysis of the second National Health and Nutrition Examination Survey data (1976\u20131980)","volume":"78","author":"Hotz","year":"2003","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.cca.2023.117397_b0035","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1093\/jn\/nxy105","article-title":"Serum zinc concentrations in the US population are related to sex, age, and time of blood draw but not dietary or supplemental zinc","volume":"148","author":"Hennigar","year":"2018","journal-title":"J Nutr."},{"key":"10.1016\/j.cca.2023.117397_b0040","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/ajcn\/56.2.440","article-title":"Serum copper and zinc in random samples of the population of Northern Ireland","volume":"56","author":"McMaster","year":"1992","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.cca.2023.117397_b0045","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/clinchem\/39.5.883","article-title":"Assessment of copper status: effect of age and gender on RIs in healthy adults","volume":"39","author":"Milne","year":"1993","journal-title":"Clin Chem"},{"issue":"3870","key":"10.1016\/j.cca.2023.117397_b0050","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1126\/science.163.3870.959.a","article-title":"Serum copper and oral estrogen","volume":"163","author":"Frieden","year":"1969","journal-title":"Science."},{"issue":"2","key":"10.1016\/j.cca.2023.117397_b0055","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00054725-199905000-00001","article-title":"The influence of cigarette smoking on cytokine levels in patients with inflammatory bowel disease","volume":"5","author":"Sher","year":"1999","journal-title":"Inflam Bowel Dis."},{"key":"10.1016\/j.cca.2023.117397_b0060","first-page":"19","article-title":"Heavy metals in tobacco and in tobacco smoke II: Trace metals cadmium, lead, copper, cobalt and nickel in Austrian cigarettes and in particle phase and smoke gas","volume":"15","author":"Nitsch","year":"1991","journal-title":"Beitr Tabakforsch"},{"issue":"5","key":"10.1016\/j.cca.2023.117397_b0065","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1378\/chest.129.5.1288","article-title":"Exhaled metallic elements and serum pneumoproteins in asymptomatic smokers and patients with COPD or asthma","volume":"129","author":"Mutti","year":"2006","journal-title":"Chest."},{"key":"10.1016\/j.cca.2023.117397_b0070","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s12011-014-9984-9","article-title":"The influence of the occupational exposure to heavy metals and tobacco smoke on the selected oxidative stress markers in smelters","volume":"159","author":"\u015aciskalska","year":"2014","journal-title":"Biolog Trace Elem Res"},{"key":"10.1016\/j.cca.2023.117397_b0075","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0048-9697(85)90011-7","article-title":"Trace elements and alcohol","volume":"15","author":"Dinsmore","year":"1985","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.cca.2023.117397_b0080","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1093\/ajcp\/60.6.870","article-title":"Serum copper in children (6\u201312 years old): an age-correction factor","volume":"60","author":"Tessmer","year":"1973","journal-title":"Am J Clin Pathol."},{"issue":"9","key":"10.1016\/j.cca.2023.117397_b0085","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1136\/jcp.37.9.1050","article-title":"Albumin bound and alpha 2-macroglobulin bound zinc concentrations in the sera of healthy adults","volume":"37","author":"Foote","year":"1984","journal-title":"J Clin Pathol."},{"issue":"3","key":"10.1016\/j.cca.2023.117397_b0090","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1258\/0004563001899429","article-title":"Effect of the inflammatory response on trace element and vitamin status","volume":"37","author":"Galloway","year":"2000","journal-title":"Ann Clin Biochem."},{"issue":"1","key":"10.1016\/j.cca.2023.117397_b0095","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3945\/ajcn.111.023812","article-title":"Quantitative data on the magnitude of the systemic inflammatory response and its effect on micronutrient status based on plasma measurements","volume":"95","author":"Duncan","year":"2012","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.cca.2023.117397_b0100","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/clinchem\/34.8.1622","article-title":"Age- and sex-specific pediatric reference intervals for biochemistry analytes as measured with the Ektachem-700 analyzer","volume":"34","author":"Lockitch","year":"1988","journal-title":"Clin Chem."},{"issue":"2","key":"10.1016\/j.cca.2023.117397_b0105","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1177\/0004563215595429","article-title":"The role of the clinical biochemist in detection of zinc-induced copper deficiency","volume":"53","author":"Duncan","year":"2016","journal-title":"Ann Clin Biochem."},{"key":"10.1016\/j.cca.2023.117397_b0110","doi-asserted-by":"crossref","first-page":"1029S","DOI":"10.1093\/ajcn\/67.5.1029S","article-title":"Diagnosis and therapy of Menkes syndrome, a genetic form of copper deficiency","volume":"67","author":"Kaler","year":"1998","journal-title":"Am J Clin Nutr."},{"issue":"6","key":"10.1016\/j.cca.2023.117397_b0115","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/ced.14605","article-title":"Dietary deprivation during the COVID-19 pandemic producing acquired vulval zinc-deficiency dermatitis","volume":"46","author":"James","year":"2021","journal-title":"Clin Experiment Derm."},{"key":"10.1016\/j.cca.2023.117397_b0120","unstructured":"O\u2019Kane M. Albumin-adjusted calcium: a position paper. https:\/\/www\/acb.org.uk\/resource\/adjusted-calcium-position-paper-march-2015-pdf.html. (2015, accessed 5th June, 2021)."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898123001997?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898123001997?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:09:58Z","timestamp":1757862598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898123001997"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":24,"alternative-id":["S0009898123001997"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2023.117397","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recommended reference intervals for copper and zinc in serum using the US National Health and Nutrition Examination surveys (NHANES) data","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2023.117397","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117397"}}