{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T20:18:25Z","timestamp":1789330705479,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.cca.2024.117801","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T02:19:14Z","timestamp":1706494754000},"page":"117801","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Performance of the digital cell morphology analyzer MC-100i in a multicenter study in tertiary hospitals in China"],"prefix":"10.1016","volume":"555","author":[{"given":"Hong","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoqin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mianyang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuling","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxue","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dehua","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2024.117801_b0005","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1532\/LH96.05019","article-title":"The international consensus group for hematology review: suggested criteria for action following automated CBC and WBC differential analysis","volume":"11","author":"Barnes","year":"2005","journal-title":"Lab. Hematol."},{"key":"10.1016\/j.cca.2024.117801_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3343\/alm.2013.33.1.1","article-title":"Purpose and criteria for blood smear scan, blood smear examination, and blood smear review","volume":"33","author":"Gulati","year":"2013","journal-title":"Ann. Lab. Med."},{"issue":"5","key":"10.1016\/j.cca.2024.117801_b0015","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1056\/NEJMra043442","article-title":"Diagnosis from the Blood Smear","volume":"353","author":"Bain","year":"2005","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0020","first-page":"137","article-title":"The imprecision of the ratio of two percentages observed in differential white blood cell counts: a warning","volume":"11","author":"R\u00fcmke","year":"1985","journal-title":"Blood Cells"},{"issue":"4","key":"10.1016\/j.cca.2024.117801_b0025","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/ijlh.13042","article-title":"Digital morphology analyzers in hematology: ICSH review and recommendations","volume":"41","author":"Kratz","year":"2019","journal-title":"Int. J. Lab. Hematol."},{"issue":"4","key":"10.1016\/j.cca.2024.117801_b0030","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12040797","article-title":"Artificial intelligence and digital microscopy applications in diagnostic hematopathology","volume":"12","author":"El Achi","year":"2020","journal-title":"Cancers (basel)"},{"key":"10.1016\/j.cca.2024.117801_b0035","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1309\/XMB9K0J41LHLATAY","article-title":"Performance evaluation of the CellaVision DM96 system: WBC differentials by automated digital image analysis supported by an artificial neural network","volume":"124","author":"Kratz","year":"2005","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.cca.2024.117801_b0040","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1111\/ijlh.13681","article-title":"Evaluation of Scopio Labs X100 Full Field PBS: The first high-resolution full field viewing of peripheral blood specimens combined with artificial intelligence-based morphological analysis","volume":"43","author":"Katz","year":"2021","journal-title":"Int. J. Lab. Hematol."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0045","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12911-023-02153-z","article-title":"Artificial intelligence of digital morphology analyzers improves the efficiency of manual leukocyte differentiation of peripheral blood","volume":"23","author":"Xing","year":"2023","journal-title":"BMC Med. Inform. Decis. Mak."},{"key":"10.1016\/j.cca.2024.117801_b0050","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1111\/ijlh.14145","article-title":"Comparison of the performance of two automatic cell morphology analyzers for peripheral-blood leukocyte morphology analysis: Mindray MC-100i and Sysmex DI-60","author":"Zhang","year":"2023","journal-title":"Int. J. Lab Hematol."},{"issue":"8","key":"10.1016\/j.cca.2024.117801_b0055","doi-asserted-by":"crossref","first-page":"e249","DOI":"10.2196\/jmir.9607","article-title":"Social media landscape of the tertiary referral hospitals in china: observational descriptive study","volume":"20","author":"Zhang","year":"2018","journal-title":"J. Med. Internet Res."},{"issue":"3","key":"10.1016\/j.cca.2024.117801_b0060","doi-asserted-by":"crossref","first-page":"276","DOI":"10.11613\/BM.2012.031","article-title":"Interrater reliability: the kappa statistic","volume":"22","author":"McHugh","year":"2012","journal-title":"Biochemia Medica"},{"key":"10.1016\/j.cca.2024.117801_b0065","unstructured":"Clinical and Laboratory Standards Institute (CLSI) 2nd ed. CLSI, Reference leukocyte (WBC) differential count (proportional) and evaluation of instrument methods: approved standard, Document H20-A2, 2007."},{"issue":"3","key":"10.1016\/j.cca.2024.117801_b0070","first-page":"69","article-title":"Statistics corner: A guide to appropriate use of correlation coefficient in medical research","volume":"24","author":"Mukaka","year":"2012","journal-title":"Malawi Med. J. Med. Assoc. Malawi"},{"key":"10.1016\/j.cca.2024.117801_b0075","unstructured":"G. International Consensus, Consensus Guidelines: Positive Smear Findings."},{"key":"10.1016\/j.cca.2024.117801_b0080","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/ijlh.12327","article-title":"ICSH recommendations for the standardization of nomenclature and grading of peripheral blood cell morphological features","volume":"37","author":"Palmer","year":"2015","journal-title":"Int. J. Lab. Hematol."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/bmsp.12167","article-title":"Hubert's multi-rater kappa revisited","volume":"73","author":"Mart\u00edn Andr\u00e9s","year":"2020","journal-title":"Br. J. Math. Stat. Psychol."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0090","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1515\/cclm-2017-0132","article-title":"Performance of automated digital cell imaging analyzer Sysmex DI-60","volume":"56","author":"Kim","year":"2017","journal-title":"Clin. Chem. Lab Med."},{"issue":"6","key":"10.1016\/j.cca.2024.117801_b0095","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1515\/cclm-2020-1701","article-title":"Performance of digital morphology analyzer Vision Pro on white blood cell differentials","volume":"59","author":"Yoon","year":"2021","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.cca.2024.117801_b0100","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1751-553X.2007.01002.x","article-title":"Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system","volume":"31","author":"Briggs","year":"2009","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.cca.2024.117801_b0105","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/ijlh.12044","article-title":"Automated digital cell morphology identification system (CellaVision DM96) is very useful for leukocyte differentials in specimens with qualitative or quantitative abnormalities","volume":"35","author":"Park","year":"2013","journal-title":"Int. J. Lab. Hematol."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0110","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1515\/cclm-2022-0829","article-title":"Performance of digital morphology analyzer CellaVision DC-1","volume":"61","author":"Lee","year":"2023","journal-title":"Clin. Chem. Labor. Med. (CCLM)"},{"key":"10.1016\/j.cca.2024.117801_b0115","first-page":"514","article-title":"The biology of acute promyelocytic leukemia and its impact on diagnosis and treatment","volume":"156\u201361","author":"Lo-Coco","year":"2006","journal-title":"Hematol. Am. Soc. Hematol. Educ. Program"},{"issue":"7","key":"10.1016\/j.cca.2024.117801_b0120","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1136\/jcp.2005.033787","article-title":"The divergent morphological classification of variant lymphocytes in blood smears","volume":"60","author":"van der Meer","year":"2007","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.cca.2024.117801_b0125","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4103\/2153-3539.151922","article-title":"Performance of the CellaVision(\u00ae) DM96 system for detecting red blood cell morphologic abnormalities","volume":"6","author":"Horn","year":"2015","journal-title":"J. Pathol. Informat."},{"key":"10.1016\/j.cca.2024.117801_b0130","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/ijlh.12497","article-title":"Evaluation of the red blood cell advanced software application on the cellavision DM96","volume":"38","author":"Criel","year":"2016","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.cca.2024.117801_b0135","doi-asserted-by":"crossref","first-page":"e98","DOI":"10.1111\/ijlh.12530","article-title":"Classification of several morphological red blood cell abnormalities by DM96 digital imaging","volume":"38","author":"Egel\u00e9","year":"2016","journal-title":"Int. J. Lab. Hematol."},{"issue":"1","key":"10.1016\/j.cca.2024.117801_b0140","doi-asserted-by":"crossref","first-page":"32","DOI":"10.29074\/ascls.27.1.32","article-title":"A survey study of benefits and limitations of using CellaVision DM96 for peripheral blood differentials","volume":"27","author":"VanVranken","year":"2014","journal-title":"Clin. Laborat. Sci."},{"issue":"4","key":"10.1016\/j.cca.2024.117801_b0145","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1309\/LM604RQVKVLRFXOR","article-title":"Detection of platelet clumps on peripheral blood smears by cellavision DM96 system and microscopic review","volume":"45","author":"Gulati","year":"2014","journal-title":"Lab. Med."},{"key":"10.1016\/j.cca.2024.117801_b0150","first-page":"194","article-title":"Performance of the CellaVision DC-1 digital cell imaging analyser for differential counting and morphological classification of blood cells","author":"van der Vorm","year":"2021","journal-title":"J. Clin. Pathol."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898124000421?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898124000421?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T15:12:12Z","timestamp":1757862732000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898124000421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":30,"alternative-id":["S0009898124000421"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2024.117801","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Performance of the digital cell morphology analyzer MC-100i in a multicenter study in tertiary hospitals in China","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2024.117801","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117801"}}