{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:56:55Z","timestamp":1786985815229,"version":"build-2736575974"},"reference-count":121,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004697","name":"Hamadan University of Medical Sciences","doi-asserted-by":"publisher","award":["1403U-1867"],"award-info":[{"award-number":["1403U-1867"]}],"id":[{"id":"10.13039\/501100004697","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.cca.2024.120041","type":"journal-article","created":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T10:05:43Z","timestamp":1731837943000},"page":"120041","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Non-coding RNA biosensors for early detection of brain cancer"],"prefix":"10.1016","volume":"566","author":[{"given":"Yousof","family":"karami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajad","family":"Ehtiati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maedeh","family":"Rafiee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Zamani Sani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Edris","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Moradi Kazerouni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Movahedpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Aiiashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyyed Hossein","family":"Khatami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0005","first-page":"270","article-title":"Cancers of the brain and CNS: global patterns and trends in incidence","volume":"19","author":"Miranda-Filho","year":"2017","journal-title":"Neuro-Oncology."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0010","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S1474-4422(18)30468-X","article-title":"Global, regional, and national burden of brain and other CNS cancer, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Patel","year":"2019","journal-title":"The Lancet Neurology."},{"key":"10.1016\/j.cca.2024.120041_b0015","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s00428-017-2181-4","article-title":"Characterization of gliomas: from morphology to molecules","volume":"471","author":"Ferris","year":"2017","journal-title":"Virchows Archiv."},{"issue":"10","key":"10.1016\/j.cca.2024.120041_b0020","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa043330","article-title":"Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma","volume":"352","author":"Stupp","year":"2005","journal-title":"New England Journal of Medicine."},{"issue":"12","key":"10.1016\/j.cca.2024.120041_b0025","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1200\/JCO.2015.62.2589","article-title":"Long-term neurocognitive functioning and social attainment in adult survivors of pediatric CNS tumors: results from the St Jude Lifetime Cohort Study","volume":"34","author":"Brinkman","year":"2016","journal-title":"Journal of Clinical Oncology."},{"issue":"3","key":"10.1016\/j.cca.2024.120041_b0030","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.ccell.2017.02.009","article-title":"The microenvironmental landscape of brain tumors","volume":"31","author":"Quail","year":"2017","journal-title":"Cancer Cell."},{"issue":"39","key":"10.1016\/j.cca.2024.120041_b0035","doi-asserted-by":"crossref","first-page":"5003","DOI":"10.1038\/onc.2014.456","article-title":"Junk DNA and the long non-coding RNA twist in cancer genetics","volume":"34","author":"Ling","year":"2015","journal-title":"Oncogene."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0040","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3892\/or.2016.5236","article-title":"Non-coding RNAs as regulators in epigenetics","volume":"37","author":"Wei","year":"2017","journal-title":"Oncology Reports."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0045","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/nrc.2017.99","article-title":"Non-coding RNA networks in cancer","volume":"18","author":"Anastasiadou","year":"2018","journal-title":"Nature Reviews Cancer."},{"key":"10.1016\/j.cca.2024.120041_b0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cca.2021.03.009","article-title":"Biosensors in Parkinson\u2019s disease","volume":"518","author":"Mobed","year":"2021","journal-title":"Clinica Chimica Acta."},{"key":"10.1016\/j.cca.2024.120041_b0055","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1007\/s00216-004-3024-0","article-title":"Trends in the development of nucleic acid biosensors for medical diagnostics","volume":"381","author":"Piunno","year":"2005","journal-title":"Analytical and Bioanalytical Chemistry."},{"issue":"7\u20138","key":"10.1016\/j.cca.2024.120041_b0060","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1080\/13547500802645905","article-title":"Biosensors for biomarkers in medical diagnostics","volume":"13","author":"Mascini","year":"2008","journal-title":"Biomarkers."},{"key":"10.1016\/j.cca.2024.120041_b0065","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1146\/annurev-anchem-061417-010007","article-title":"DNA nanotechnology-enabled interfacial engineering for biosensor development","volume":"11","author":"Ye","year":"2018","journal-title":"Annual Review of Analytical Chemistry."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0070","doi-asserted-by":"crossref","first-page":"86","DOI":"10.4068\/cmj.2019.55.2.86","article-title":"Recent advances in biosensors for nucleic acid and exosome detection","volume":"55","author":"Fu","year":"2019","journal-title":"Chonnam Medical Journal."},{"issue":"11","key":"10.1016\/j.cca.2024.120041_b0075","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3390\/bios10110186","article-title":"Electrochemical biosensors for detection of microRNA as a cancer biomarker: Pros and cons","volume":"10","author":"El Aamri","year":"2020","journal-title":"Biosensors."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0080","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1021\/ac8024653","article-title":"Disposable nucleic acid biosensors based on gold nanoparticle probes and lateral flow strip","volume":"81","author":"Mao","year":"2009","journal-title":"Analytical Chemistry."},{"issue":"7","key":"10.1016\/j.cca.2024.120041_b0085","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1039\/c3an01677c","article-title":"Biosensor-based microRNA detection: techniques, design, performance, and challenges","volume":"139","author":"Johnson","year":"2014","journal-title":"Analyst."},{"key":"10.1016\/j.cca.2024.120041_b0090","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.snb.2018.03.045","article-title":"A new DNA sensor design for the simultaneous detection of HPV type 16 and 18 DNA","volume":"265","author":"Jampasa","year":"2018","journal-title":"Sensors and Actuators B: Chemical."},{"key":"10.1016\/j.cca.2024.120041_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1479-7364-5-2-90","article-title":"Naming'junk': human non-protein coding RNA (ncRNA) gene nomenclature","volume":"5","author":"Wright","year":"2011","journal-title":"Human Genomics."},{"issue":"9","key":"10.1016\/j.cca.2024.120041_b0100","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1101\/gr.132159.111","article-title":"The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression","volume":"22","author":"Derrien","year":"2012","journal-title":"Genome Research."},{"issue":"8","key":"10.1016\/j.cca.2024.120041_b0105","doi-asserted-by":"crossref","first-page":"4659","DOI":"10.1007\/s12035-023-03365-0","article-title":"Exosomes: promising delivery tools for overcoming blood-brain barrier and glioblastoma therapy","volume":"60","author":"Khatami","year":"2023","journal-title":"Molecular Neurobiology."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0110","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1002\/jcp.30697","article-title":"Exosomal microRNAs and long noncoding RNAs: Novel mediators of drug resistance in lung cancer","volume":"237","author":"Taghvimi","year":"2022","journal-title":"Journal of Cellular Physiology."},{"key":"10.1016\/j.cca.2024.120041_b0115","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.cca.2022.10.018","article-title":"Exosomal noncoding RNAs in prostate cancer","volume":"537","author":"Movahedpour","year":"2022","journal-title":"Clinica Chimica Acta."},{"issue":"18","key":"10.1016\/j.cca.2024.120041_b0120","first-page":"1965","article-title":"Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis","volume":"130","author":"Alvarez-Dominguez","year":"2017","journal-title":"Blood, the Journal of the American Society of Hematology."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0125","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.cell.2011.03.014","article-title":"No-nonsense functions for long noncoding RNAs","volume":"145","author":"Nagano","year":"2011","journal-title":"Cell."},{"key":"10.1016\/j.cca.2024.120041_b0130","first-page":"83","article-title":"Long non-coding RNA. Genomic Elements in Health, Disease and Evolution: Junk","author":"Gullerova","year":"2015","journal-title":"DNA."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0135","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/15476286.2015.1020271","article-title":"Regulation of circRNA biogenesis","volume":"12","author":"Chen","year":"2015","journal-title":"RNA Biology."},{"key":"10.1016\/j.cca.2024.120041_b0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12943-020-01298-z","article-title":"Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies","volume":"20","author":"Wang","year":"2021","journal-title":"Molecular Cancer."},{"key":"10.1016\/j.cca.2024.120041_b0145","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.gde.2017.11.007","article-title":"circRNAs in cancer","volume":"48","author":"Patop","year":"2018","journal-title":"Current Opinion in Genetics & Development."},{"issue":"6","key":"10.1016\/j.cca.2024.120041_b0150","first-page":"1167","article-title":"Circular RNAs as potential biomarkers for cancer diagnosis and therapy","volume":"6","author":"Wang","year":"2016","journal-title":"American Journal of Cancer Research."},{"issue":"12","key":"10.1016\/j.cca.2024.120041_b0155","doi-asserted-by":"crossref","first-page":"6147","DOI":"10.1002\/cam4.1613","article-title":"Dysregulated circular RNA s in medulloblastoma regulate proliferation and growth of tumor cells via host genes","volume":"7","author":"Lv","year":"2018","journal-title":"Cancer Medicine."},{"key":"10.1016\/j.cca.2024.120041_b0160","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jocn.2021.01.020","article-title":"Circ-SKA3 upregulates ID3 expression by decoying miR-326 to accelerate the development of medulloblastoma","volume":"86","author":"Zhao","year":"2021","journal-title":"Journal of Clinical Neuroscience."},{"key":"10.1016\/j.cca.2024.120041_b0165","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3389\/fnagi.2018.00305","article-title":"Recent advances in biomarkers for Parkinson\u2019s disease","volume":"10","author":"He","year":"2018","journal-title":"Frontiers in Aging Neuroscience."},{"key":"10.1016\/j.cca.2024.120041_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147108","article-title":"Knockdown of circ0082374 inhibits cell viability, migration, invasion and glycolysis in glioma cells by miR-326\/SIRT1","volume":"1748","author":"Wang","year":"2020","journal-title":"Brain Research."},{"issue":"21","key":"10.1016\/j.cca.2024.120041_b0175","doi-asserted-by":"crossref","first-page":"21114","DOI":"10.18632\/aging.103603","article-title":"Hsa_circ_0043278 functions as competitive endogenous RNA to enhance glioblastoma multiforme progression by sponging miR-638","volume":"12","author":"Wu","year":"2020","journal-title":"Aging (Albany NY)."},{"issue":"9","key":"10.1016\/j.cca.2024.120041_b0180","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1089\/dna.2018.4294","article-title":"hsa_circ_0000177-miR-638-FZD7-Wnt Signaling Cascade Contributes to the Malignant Behaviors in Glioma","volume":"37","author":"Chen","year":"2018","journal-title":"DNA and Cell Biology."},{"key":"10.1016\/j.cca.2024.120041_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12943-020-01271-w","article-title":"Correction to: EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis","volume":"19","author":"Wang","year":"2020","journal-title":"Molecular Cancer."},{"key":"10.1016\/j.cca.2024.120041_b0190","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.757260","article-title":"A novel circular RNA CircRFX3 serves as a sponge for MicroRNA-587 in promoting glioblastoma progression via regulating PDIA3","volume":"9","author":"Li","year":"2021","journal-title":"Frontiers in Cell and Developmental Biology."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13046-020-01625-8","article-title":"SRSF10 inhibits biogenesis of circ-ATXN1 to regulate glioma angiogenesis via miR-526b-3p\/MMP2 pathway","volume":"39","author":"Liu","year":"2020","journal-title":"Journal of Experimental & Clinical Cancer Research."},{"key":"10.1016\/j.cca.2024.120041_b0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13046-020-01691-y","article-title":"The U2AF2\/circRNA ARF1\/miR-342\u20133p\/ISL2 feedback loop regulates angiogenesis in glioma stem cells","volume":"39","author":"Jiang","year":"2020","journal-title":"Journal of Experimental & Clinical Cancer Research."},{"key":"10.1016\/j.cca.2024.120041_b0205","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.801776","article-title":"CircPIK3C2A facilitates the progression of glioblastoma via targeting miR-877-5p\/FOXM1 axis","volume":"11","author":"Yang","year":"2021","journal-title":"Frontiers in Oncology."},{"issue":"13","key":"10.1016\/j.cca.2024.120041_b0210","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1038\/s41388-017-0019-9","article-title":"A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis","volume":"37","author":"Zhang","year":"2018","journal-title":"Oncogene."},{"issue":"3","key":"10.1016\/j.cca.2024.120041_b0215","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/jnci\/djx166","article-title":"Novel role of FBXW7 circular RNA in repressing glioma tumorigenesis","volume":"110","author":"Yang","year":"2018","journal-title":"JNCI: Journal of the National Cancer Institute."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12943-020-01253-y","article-title":"Circular RNA CDR1as disrupts the p53\/MDM2 complex to inhibit Gliomagenesis","volume":"19","author":"Lou","year":"2020","journal-title":"Molecular Cancer."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0225","doi-asserted-by":"crossref","first-page":"318","DOI":"10.18632\/aging.102617","article-title":"Circ-EPB41L5 regulates the host gene EPB41L5 via sponging miR-19a to repress glioblastoma tumorigenesis","volume":"12","author":"Lv","year":"2020","journal-title":"Aging (Albany NY)."},{"key":"10.1016\/j.cca.2024.120041_b0230","first-page":"1","article-title":"A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1","volume":"18","author":"Xia","year":"2019","journal-title":"Molecular Cancer."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0235","first-page":"1373","article-title":"Identification of the tumor-suppressive function of circular RNA ITCH in glioma cells through sponging miR-214 and promoting linear ITCH expression","volume":"10","author":"Li","year":"2018","journal-title":"American Journal of Translational Research."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0240","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3390\/ijms19020480","article-title":"CircSMARCA5 inhibits migration of glioblastoma multiforme cells by regulating a molecular axis involving splicing factors SRSF1\/SRSF3\/PTB","volume":"19","author":"Barbagallo","year":"2018","journal-title":"International Journal of Molecular Sciences."},{"issue":"8","key":"10.1016\/j.cca.2024.120041_b0245","doi-asserted-by":"crossref","first-page":"13807","DOI":"10.1002\/jcp.28061","article-title":"Circular RNA circ_0001946 acts as a competing endogenous RNA to inhibit glioblastoma progression by modulating miR-671-5p and CDR1","volume":"234","author":"Li","year":"2019","journal-title":"Journal of Cellular Physiology."},{"key":"10.1016\/j.cca.2024.120041_b0250","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.omtn.2021.08.026","article-title":"LRRC4 mediates the formation of circular RNA CD44 to inhibit GBM cell proliferation","volume":"26","author":"Feng","year":"2021","journal-title":"Molecular Therapy-Nucleic Acids."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0255","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/carcin\/bgx026","article-title":"Small non-coding RNA and cancer","volume":"38","author":"Romano","year":"2017","journal-title":"Carcinogenesis."},{"issue":"8","key":"10.1016\/j.cca.2024.120041_b0260","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/nrg3495","article-title":"PIWI-interacting RNAs: from generation to transgenerational epigenetics","volume":"14","author":"Luteijn","year":"2013","journal-title":"Nature Reviews Genetics."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000484541","article-title":"PIWI Proteins and PIWI-Interacting RNA: Emerging Roles in Cancer","volume":"44","author":"Han","year":"2017","journal-title":"Cellular Physiology and Biochemistry: International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology."},{"issue":"7483","key":"10.1016\/j.cca.2024.120041_b0270","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nature12987","article-title":"PIWI proteins and PIWI-interacting RNAs in the soma","volume":"505","author":"Ross","year":"2014","journal-title":"Nature."},{"key":"10.1016\/j.cca.2024.120041_b0275","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/978-94-017-7417-8_4","article-title":"The piRNA pathway guards the germline genome against transposable elements","volume":"886","author":"T\u00f3th","year":"2016","journal-title":"Advances in Experimental Medicine and Biology."},{"key":"10.1016\/j.cca.2024.120041_b0280","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s13045-015-0133-5","article-title":"piRNA involvement in genome stability and human cancer","volume":"8","author":"Moyano","year":"2015","journal-title":"Journal of Hematology & Oncology."},{"issue":"6","key":"10.1016\/j.cca.2024.120041_b0285","doi-asserted-by":"crossref","first-page":"975","DOI":"10.2217\/epi.15.37","article-title":"The role of piRNA and its potential clinical implications in cancer","volume":"7","author":"Assump\u00e7\u00e3o","year":"2015","journal-title":"Epigenomics."},{"issue":"102","key":"10.1016\/j.cca.2024.120041_b0290","doi-asserted-by":"crossref","first-page":"37616","DOI":"10.18632\/oncotarget.26331","article-title":"piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo","volume":"9","author":"Jacobs","year":"2018","journal-title":"Oncotarget."},{"key":"10.1016\/j.cca.2024.120041_b0295","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.omtn.2017.12.020","article-title":"PIWIL1\/piRNA-DQ593109 regulates the permeability of the blood-tumor barrier via the MEG3\/miR-330-5p\/RUNX3 axis","volume":"10","author":"Shen","year":"2018","journal-title":"Molecular Therapy-Nucleic Acids."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0300","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.7150\/thno.21740","article-title":"PIWIL3\/OIP5-AS1\/miR-367-3p\/CEBPA feedback loop regulates the biological behavior of glioma cells","volume":"8","author":"Liu","year":"2018","journal-title":"Theranostics."},{"issue":"7","key":"10.1016\/j.cca.2024.120041_b0305","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1158\/1055-9965.EPI-16-0047","article-title":"PIWI-interacting RNAs in gliomagenesis: evidence from post-GWAS and functional analyses","volume":"25","author":"Jacobs","year":"2016","journal-title":"Cancer Epidemiology, Biomarkers & Prevention."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0310","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/s41580-020-00315-9","article-title":"Gene regulation by long non-coding RNAs and its biological functions","volume":"22","author":"Statello","year":"2021","journal-title":"Nature Reviews Molecular Cell Biology."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0315","doi-asserted-by":"crossref","first-page":"367","DOI":"10.14348\/molcells.2016.0039","article-title":"Incredible RNA: dual functions of coding and noncoding","volume":"39","author":"Nam","year":"2016","journal-title":"Molecules and Cells."},{"issue":"8","key":"10.1016\/j.cca.2024.120041_b0320","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1002\/cbf.3671","article-title":"microRNAs in female infertility: An overview","volume":"39","author":"Bahmyari","year":"2021","journal-title":"Cell Biochemistry and Function."},{"key":"10.1016\/j.cca.2024.120041_b0325","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.853180","article-title":"The emerging roles of the \u03b2-secretase BACE1 and the long non-coding RNA BACE1-AS in human diseases: a focus on neurodegenerative diseases and cancer","volume":"14","author":"Sayad","year":"2022","journal-title":"Frontiers in Aging Neuroscience."},{"key":"10.1016\/j.cca.2024.120041_b0330","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00109-014-1131-8","article-title":"Long non-coding RNA in health and disease","volume":"92","author":"Maass","year":"2014","journal-title":"Journal of Molecular Medicine."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0335","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.gpb.2015.09.006","article-title":"Roles, functions, and mechanisms of long non-coding RNAs in cancer","volume":"14","author":"Fang","year":"2016","journal-title":"Genomics, Proteomics & Bioinformatics."},{"key":"10.1016\/j.cca.2024.120041_b0340","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.molimm.2019.04.011","article-title":"Long non-coding RNA: Classification, biogenesis and functions in blood cells","volume":"112","author":"Dahariya","year":"2019","journal-title":"Molecular Immunology."},{"issue":"18","key":"10.1016\/j.cca.2024.120041_b0345","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1101\/gad.17446611","article-title":"Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses","volume":"25","author":"Cabili","year":"2011","journal-title":"Genes & Development."},{"issue":"12","key":"10.1016\/j.cca.2024.120041_b0350","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1002\/ijc.32400","article-title":"The long noncoding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells","volume":"145","author":"Varon","year":"2019","journal-title":"International Journal of Cancer."},{"issue":"6","key":"10.1016\/j.cca.2024.120041_b0355","doi-asserted-by":"crossref","first-page":"591","DOI":"10.3727\/096504020X15982623243955","article-title":"Long noncoding RNA WEE2-AS1 plays an oncogenic role in glioblastoma by functioning as a molecular sponge for microRNA-520f-3p","volume":"28","author":"Lin","year":"2021","journal-title":"Oncology Research."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0360","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13046-018-0941-x","article-title":"Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a\/EZH2\/Dnmts away from the HOXA1 gene in glioblastoma multiforme","volume":"37","author":"Li","year":"2018","journal-title":"Journal of Experimental & Clinical Cancer Research."},{"key":"10.1016\/j.cca.2024.120041_b0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12885-020-07280-8","article-title":"SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p\/ERLIN2 axis","volume":"20","author":"Du","year":"2020","journal-title":"BMC Cancer."},{"issue":"6","key":"10.1016\/j.cca.2024.120041_b0370","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20170871","article-title":"Long non-coding RNA PVT1 indicates a poor prognosis of glioma and promotes cell proliferation and invasion via target EZH2","volume":"37","author":"Yang","year":"2017","journal-title":"Bioscience Reports."},{"key":"10.1016\/j.cca.2024.120041_b0375","article-title":"Long noncoding RNA HOTAIR promotes medulloblastoma growth, migration and invasion by sponging miR-1\/miR-206 and targeting YY1","volume":"124","author":"Zhang","year":"2020","journal-title":"Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie."},{"issue":"14","key":"10.1016\/j.cca.2024.120041_b0380","doi-asserted-by":"crossref","first-page":"886","DOI":"10.21037\/atm-20-5006","article-title":"Medulloblastoma malignant biological behaviors are associated with HOTAIR\/miR-483-3p\/CDK4 axis","volume":"8","author":"Zhao","year":"2020","journal-title":"Annals of Translational Medicine."},{"issue":"12","key":"10.1016\/j.cca.2024.120041_b0385","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1038\/mt.2015.170","article-title":"Gas5 Exerts Tumor-suppressive Functions in Human Glioma Cells by Targeting miR-222","volume":"23","author":"Zhao","year":"2015","journal-title":"Molecular Therapy : the Journal of the American Society of Gene Therapy."},{"key":"10.1016\/j.cca.2024.120041_b0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2019.113349","article-title":"Electrochemical-based biosensors for microRNA detection: Nanotechnology comes into view","volume":"581","author":"Shabaninejad","year":"2019","journal-title":"Analytical Biochemistry."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0395","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41580-018-0045-7","article-title":"Regulation of microRNA function in animals","volume":"20","author":"Gebert","year":"2019","journal-title":"Nature Reviews Molecular Cell Biology."},{"key":"10.1016\/j.cca.2024.120041_b0400","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3389\/fendo.2018.00402","article-title":"Overview of microRNA biogenesis, mechanisms of actions, and circulation","volume":"9","author":"O'Brien","year":"2018","journal-title":"Frontiers in Endocrinology."},{"key":"10.1016\/j.cca.2024.120041_b0405","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12885-017-3198-4","article-title":"Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c","volume":"17","author":"Dalan","year":"2017","journal-title":"BMC Cancer."},{"issue":"9","key":"10.1016\/j.cca.2024.120041_b0410","doi-asserted-by":"crossref","first-page":"e0137845","DOI":"10.1371\/journal.pone.0137845","article-title":"microRNA-10b is overexpressed and critical for cell survival and proliferation in medulloblastoma","volume":"10","author":"Pal","year":"2015","journal-title":"Plos One."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0415","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1158\/0008-5472.CAN-13-1449","article-title":"microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma","volume":"74","author":"Kim","year":"2014","journal-title":"Cancer Research."},{"issue":"7","key":"10.1016\/j.cca.2024.120041_b0420","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/cas.12946","article-title":"MicroRNA-124-3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma","volume":"107","author":"Deng","year":"2016","journal-title":"Cancer Science."},{"issue":"3","key":"10.1016\/j.cca.2024.120041_b0425","doi-asserted-by":"crossref","first-page":"932","DOI":"10.18632\/aging.101201","article-title":"MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2","volume":"9","author":"Werner","year":"2017","journal-title":"Aging (Albany NY)."},{"issue":"10","key":"10.1016\/j.cca.2024.120041_b0430","doi-asserted-by":"crossref","first-page":"e109124","DOI":"10.1371\/journal.pone.0109124","article-title":"MiR-181b-5p downregulates NOVA1 to suppress proliferation, migration and invasion and promote apoptosis in astrocytoma","volume":"9","author":"Zhi","year":"2014","journal-title":"PLoS One."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0435","first-page":"1957","article-title":"miR-378a-3p inhibits cellular proliferation and migration in glioblastoma multiforme by targeting tetraspanin 17","volume":"42","author":"Guo","year":"2019","journal-title":"Oncology Reports."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0440","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.3892\/or.2017.5939","article-title":"Regulation of UHRF1 by microRNA-378 modulates medulloblastoma cell proliferation and apoptosis","volume":"38","author":"Zhang","year":"2017","journal-title":"Oncology Reports."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0445","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s12920-019-0538-z","article-title":"Defining housekeeping genes suitable for RNA-seq analysis of the human allograft kidney biopsy tissue","volume":"12","author":"Wang","year":"2019","journal-title":"BMC Medical Genomics."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0450","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/nrg.2015.3","article-title":"RNA mis-splicing in disease","volume":"17","author":"Scotti","year":"2016","journal-title":"Nature Reviews Genetics."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0455","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.molcel.2012.07.033","article-title":"Long noncoding RNAs with snoRNA ends","volume":"48","author":"Yin","year":"2012","journal-title":"Molecular Cell."},{"issue":"3","key":"10.1016\/j.cca.2024.120041_b0460","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0955-0674(02)00334-4","article-title":"Biogenesis of small nucleolar ribonucleoproteins","volume":"14","author":"Filipowicz","year":"2002","journal-title":"Current Opinion in Cell Biology."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0465","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/bies.201200117","article-title":"Processing of snoRNAs as a new source of regulatory non-coding RNAs: snoRNA fragments form a new class of functional RNAs","volume":"35","author":"Falaleeva","year":"2013","journal-title":"BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0470","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nsmb.2939","article-title":"Noncoding RNAs in eukaryotic ribosome biogenesis and function","volume":"22","author":"Lafontaine","year":"2015","journal-title":"Nature Structural & Molecular Biology."},{"key":"10.1016\/j.cca.2024.120041_b0475","doi-asserted-by":"crossref","first-page":"10966","DOI":"10.1038\/ncomms10966","article-title":"Cajal bodies are linked to genome conformation","volume":"7","author":"Wang","year":"2016","journal-title":"Nature Communications."},{"key":"10.1016\/j.cca.2024.120041_b0480","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.biochi.2019.05.006","article-title":"SnoRNAs and the emerging class of sdRNAs: Multifaceted players in oncogenesis","volume":"164","author":"Abel","year":"2019","journal-title":"Biochimie."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0485","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.molcel.2008.10.017","article-title":"A human snoRNA with microRNA-like functions","volume":"32","author":"Ender","year":"2008","journal-title":"Molecular Cell."},{"issue":"9","key":"10.1016\/j.cca.2024.120041_b0490","doi-asserted-by":"crossref","first-page":"e1000507","DOI":"10.1371\/journal.pcbi.1000507","article-title":"Human miRNA precursors with box H\/ACA snoRNA features","volume":"5","author":"Scott","year":"2009","journal-title":"PLoS Computational Biology."},{"issue":"27","key":"10.1016\/j.cca.2024.120041_b0495","doi-asserted-by":"crossref","first-page":"43953","DOI":"10.18632\/oncotarget.16693","article-title":"SNORD47, a box C\/D snoRNA, suppresses tumorigenesis in glioblastoma","volume":"8","author":"Xu","year":"2017","journal-title":"Oncotarget."},{"key":"10.1016\/j.cca.2024.120041_b0500","series-title":"Chemical sensors and biosensors for medical and biological applications","author":"Spichiger-Keller","year":"2008"},{"issue":"7","key":"10.1016\/j.cca.2024.120041_b0505","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1002\/elan.201501174","article-title":"Electrochemical biosensors for cancer biomarkers detection: Recent advances and challenges","volume":"28","author":"Topkaya","year":"2016","journal-title":"Electroanalysis."},{"issue":"21","key":"10.1016\/j.cca.2024.120041_b0510","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27217327","article-title":"Recent Progress in Biosensors for Detection of Tumor Biomarkers","volume":"27","author":"Li","year":"2022","journal-title":"Molecules."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0515","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4103\/japtr.japtr_106_22","article-title":"Cancer and disease diagnosis - biosensor as potential diagnostic tool for biomarker detection","volume":"13","author":"Chaudhry","year":"2022","journal-title":"Journal of Advanced Pharmaceutical Technology & Research"},{"issue":"19","key":"10.1016\/j.cca.2024.120041_b0520","doi-asserted-by":"crossref","first-page":"5605","DOI":"10.3390\/s20195605","article-title":"Biosensors based on mechanical and electrical detection techniques","volume":"20","author":"Chalklen","year":"2020","journal-title":"Sensors."},{"issue":"21","key":"10.1016\/j.cca.2024.120041_b0525","doi-asserted-by":"crossref","first-page":"7327","DOI":"10.3390\/molecules27217327","article-title":"Recent progress in biosensors for detection of tumor biomarkers","volume":"27","author":"Li","year":"2022","journal-title":"Molecules."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0530","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/s44222-023-00032-w","article-title":"Device integration of electrochemical biosensors","volume":"1","author":"Wu","year":"2023","journal-title":"Nature Reviews Bioengineering."},{"key":"10.1016\/j.cca.2024.120041_b0535","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/3130469","article-title":"Biosensors in health care: the milestones achieved in their development towards lab-on-chip-analysis","author":"Patel","year":"2016","journal-title":"Biochemistry Research International."},{"key":"10.1016\/j.cca.2024.120041_b0540","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.aej.2022.09.020","article-title":"Brain tumors biomedical sensor with high-quality factor and ultra-compact size based on nanocavity 2D photonic crystal","volume":"64","author":"Mohammed","year":"2023","journal-title":"Alexandria Engineering Journal."},{"issue":"1","key":"10.1016\/j.cca.2024.120041_b0545","doi-asserted-by":"crossref","first-page":"8115","DOI":"10.1038\/s41598-023-34601-1","article-title":"Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa2Cu3O7\/dielectric material as a 1D defective photonic crystal","volume":"13","author":"Malek","year":"2023","journal-title":"Scientific Reports."},{"issue":"11","key":"10.1016\/j.cca.2024.120041_b0550","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1002\/jrs.6224","article-title":"Rapid diagnosis of lung cancer and glioma based on serum Raman spectroscopy combined with deep learning","volume":"52","author":"Chen","year":"2021","journal-title":"Journal of Raman Spectroscopy."},{"issue":"5","key":"10.1016\/j.cca.2024.120041_b0555","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.1021\/acs.analchem.9b05241","article-title":"An electrochemical biosensor designed by using Zr-based metal\u2013organic frameworks for the detection of glioblastoma-derived exosomes with practical application","volume":"92","author":"Sun","year":"2020","journal-title":"Analytical Chemistry."},{"issue":"35","key":"10.1016\/j.cca.2024.120041_b0560","doi-asserted-by":"crossref","first-page":"10471","DOI":"10.1002\/anie.201705615","article-title":"An electrochemical biosensor with dual signal outputs: toward simultaneous quantification of pH and O2 in the brain upon ischemia and in a tumor during cancer starvation therapy","volume":"56","author":"Liu","year":"2017","journal-title":"Angewandte Chemie International Edition."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0565","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3390\/cryst12040540","article-title":"Employing the defective photonic crystal composed of nanocomposite superconducting material in detection of cancerous brain tumors biosensor: computational study","volume":"12","author":"Malek","year":"2022","journal-title":"Crystals."},{"issue":"6","key":"10.1016\/j.cca.2024.120041_b0570","doi-asserted-by":"crossref","first-page":"5548","DOI":"10.1109\/JSEN.2022.3150516","article-title":"Graphene\/Si-based biosensor for glioblastoma cancer cell detection","volume":"22","author":"Khamsavi","year":"2022","journal-title":"IEEE Sensors Journal."},{"key":"10.1016\/j.cca.2024.120041_b0575","first-page":"1","article-title":"Photonic crystal-based nanoscale multipurpose biosensor for detection of brain tumours, HIV, and anaemia with high sensitivity","author":"Britto","year":"2024","journal-title":"Plasmonics."},{"issue":"4","key":"10.1016\/j.cca.2024.120041_b0580","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.3390\/s21041333","article-title":"Raman spectroscopy-based quality control of \u201cSilicon-On-Insulator\u201d nanowire chips for the detection of brain cancer-associated microrna in plasma","volume":"21","author":"Malsagova","year":"2021","journal-title":"Sensors."},{"issue":"2","key":"10.1016\/j.cca.2024.120041_b0585","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/bab.2374","article-title":"Evaluating glioma-associated microRNA by complementation on a biological nanosensor","volume":"70","author":"Li","year":"2023","journal-title":"Biotechnology and Applied Biochemistry."},{"issue":"3","key":"10.1016\/j.cca.2024.120041_b0590","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00604-022-05210-y","article-title":"Electrochemical biosensing of circulating microRNA-21 in cerebrospinal fluid of medulloblastoma patients through target-induced redox signal amplification","volume":"189","author":"Wang","year":"2022","journal-title":"Microchimica Acta."},{"key":"10.1016\/j.cca.2024.120041_b0595","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bioactmat.2021.11.033","article-title":"Magnetic covalent organic framework nanospheres-based miRNA biosensor for sensitive glioma detection","volume":"14","author":"Liang","year":"2022","journal-title":"Bioactive Materials."},{"issue":"7","key":"10.1016\/j.cca.2024.120041_b0600","doi-asserted-by":"crossref","first-page":"237","DOI":"10.3390\/bios11070237","article-title":"Nanoribbon-based electronic detection of a glioma-associated circular miRNA","volume":"11","author":"Ivanov","year":"2021","journal-title":"Biosensors."},{"issue":"12","key":"10.1016\/j.cca.2024.120041_b0605","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.3390\/molecules26123715","article-title":"Micro-Raman characterization of structural features of high-k stack layer of SOI nanowire chip, designed to detect circular RNA associated with the development of glioma","volume":"26","author":"Ivanov","year":"2021","journal-title":"Molecules."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898124022940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898124022940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T12:01:05Z","timestamp":1733572865000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898124022940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":121,"alternative-id":["S0009898124022940"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2024.120041","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-coding RNA biosensors for early detection of brain cancer","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2024.120041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120041"}}