{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T01:13:58Z","timestamp":1783646038427,"version":"3.55.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82400819"],"award-info":[{"award-number":["82400819"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515220047"],"award-info":[{"award-number":["2023A1515220047"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.cca.2026.121104","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T06:51:59Z","timestamp":1779432719000},"page":"121104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Urinary N-glycoproteins from the PRM-SSS discrepancy: a novel diagnostic tool for tubular injury"],"prefix":"10.1016","volume":"590","author":[{"given":"Jingjing","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youlin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10518","key":"10.1016\/j.cca.2026.121104_bb0005","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1016\/S0140-6736(25)01853-7","article-title":"Global, regional, and national burden of chronic kidney disease in adults, 1990\u20132023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023","volume":"406","year":"2025","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.cca.2026.121104_bb0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/s41581-024-00922-1","article-title":"Insights into the mechanisms of fibrosis and progressive kidney injury","volume":"21","author":"Lamas","year":"2025","journal-title":"Nat. Rev. Nephrol."},{"issue":"3","key":"10.1016\/j.cca.2026.121104_bb0015","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.kint.2017.09.033","article-title":"Renal tubule injury: a driving force toward chronic kidney disease","volume":"93","author":"Liu","year":"2018","journal-title":"Kidney Int."},{"issue":"8","key":"10.1016\/j.cca.2026.121104_bb0020","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1681\/ASN.2015060647","article-title":"Severity and frequency of proximal tubule injury determines renal prognosis","volume":"27","author":"Takaori","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.cca.2026.121104_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2024.1478697","article-title":"Tubulointerstitial injury in proteinuric chronic kidney diseases","volume":"11","author":"Cortinovis","year":"2024","journal-title":"Front. Med."},{"issue":"6","key":"10.1016\/j.cca.2026.121104_bb0030","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1681\/ASN.0000000705","article-title":"Toward assessment of tubular function in kidney disease","volume":"36","author":"Beckmann","year":"2025","journal-title":"J. Am. Soc. Nephrol."},{"issue":"5","key":"10.1016\/j.cca.2026.121104_bb0035","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1053\/j.ajkd.2021.03.026","article-title":"The promise of tubule biomarkers in kidney disease: a review","volume":"78","author":"Ix","year":"2021","journal-title":"Am. J. Kidney Dis."},{"issue":"4","key":"10.1016\/j.cca.2026.121104_bb0040","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/ndt\/gfad215","article-title":"Tubular toxicity of proteinuria and the progression of chronic kidney disease","volume":"39","author":"Makhammajanov","year":"2024","journal-title":"Nephrol. Dial. Transplant."},{"issue":"9","key":"10.1016\/j.cca.2026.121104_bb0045","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2006-7-9-r80","article-title":"The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins","volume":"7","author":"Adachi","year":"2006","journal-title":"Genome Biol."},{"issue":"8","key":"10.1016\/j.cca.2026.121104_bb0050","doi-asserted-by":"crossref","first-page":"R72","DOI":"10.1186\/gb-2006-7-8-r72","article-title":"Identification of 491 proteins in the tear fluid proteome reveals a large number of proteases and protease inhibitors","volume":"7","author":"de Souza","year":"2006","journal-title":"Genome Biol."},{"issue":"6","key":"10.1016\/j.cca.2026.121104_bb0055","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1021\/pr2003038","article-title":"A comprehensive map of the human urinary proteome","volume":"10","author":"Marimuthu","year":"2011","journal-title":"J. Proteome Res."},{"issue":"8","key":"10.1016\/j.cca.2026.121104_bb0060","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1093\/clinchem\/32.8.1551","article-title":"Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer","volume":"32","author":"Watanabe","year":"1986","journal-title":"Clin. Chem."},{"issue":"4","key":"10.1016\/j.cca.2026.121104_bb0065","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s12291-016-0551-3","article-title":"Comparison of urinary total proteins by four different methods","volume":"31","author":"Yalamati","year":"2016","journal-title":"Indian J. Clin. Biochem."},{"issue":"12","key":"10.1016\/j.cca.2026.121104_bb0070","article-title":"Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of proteins","volume":"2021","author":"Kielkopf","year":"2021","journal-title":"Cold Spring Harb. Protoc."},{"issue":"8","key":"10.1016\/j.cca.2026.121104_bb0075","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/ki.2009.550","article-title":"Tamm-Horsfall protein and urinary exosome isolation","volume":"77","author":"Fern\u00e1ndez-Llama","year":"2010","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.cca.2026.121104_bb0080","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1093\/ndt\/gfr708","article-title":"The value of simultaneous measurements of urinary albumin and total protein in proteinuric patients","volume":"27","author":"Smith","year":"2012","journal-title":"Nephrol. Dial. Transplant."},{"issue":"6","key":"10.1016\/j.cca.2026.121104_bb0085","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1016\/j.ekir.2024.03.013","article-title":"Systematic review of kidney injury biomarkers for the evaluation of CKD of uncertain etiology","volume":"9","author":"Claudel","year":"2024","journal-title":"Kidney. Int. Rep."},{"issue":"8","key":"10.1016\/j.cca.2026.121104_bb0090","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41569-024-00998-z","article-title":"Protein glycosylation in cardiovascular health and disease","volume":"21","author":"Chatham","year":"2024","journal-title":"Nat. Rev. Cardiol."},{"issue":"3","key":"10.1016\/j.cca.2026.121104_bb0095","doi-asserted-by":"crossref","DOI":"10.1093\/pcmedi\/pbaf017","article-title":"Glycosylation in kidney diseases","volume":"8","author":"Ling","year":"2025","journal-title":"Precis Clin. Med."},{"key":"10.1016\/j.cca.2026.121104_bb0100","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/214715","article-title":"Urine glycoprotein profile reveals novel markers for chronic kidney disease","volume":"2011","author":"Vivekanandan-Giri","year":"2011","journal-title":"Int. J. Proteomics."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989812600286X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000989812600286X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:30:19Z","timestamp":1783643419000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000989812600286X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":20,"alternative-id":["S000989812600286X"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2026.121104","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary N-glycoproteins from the PRM-SSS discrepancy: a novel diagnostic tool for tubular injury","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2026.121104","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121104"}}