{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:12:05Z","timestamp":1788901925238,"version":"build-2803163510"},"reference-count":232,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005713","name":"Technical University of Munich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005713","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.cca.2026.121171","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:24:09Z","timestamp":1781076249000},"page":"121171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["In-vitro diagnostics of adult immune thrombocytopenia - status quo and new developments"],"prefix":"10.1016","volume":"592","author":[{"given":"Susanne","family":"Weber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Luppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus A.","family":"Thaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Ruland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich J.","family":"Sachs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cca.2026.121171_bb0005","article-title":"Current concepts in the diagnosis and Management of Adult Primary Immune Thrombocytopenia: our personal view","volume":"59","author":"Gonz\u00e1lez-L\u00f3pez","year":"2023","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.cca.2026.121171_bb0010","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.hoc.2013.03.001","article-title":"Immune thrombocytopenia","volume":"27","author":"Kistangari","year":"2013","journal-title":"Hematol. Oncol. Clin. North Am."},{"key":"10.1016\/j.cca.2026.121171_bb0015","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1182\/asheducation-2015.1.237","article-title":"Bleeding complications in immune thrombocytopenia","volume":"2015","author":"Arnold","year":"2015","journal-title":"Hematology"},{"key":"10.1016\/j.cca.2026.121171_bb0020","article-title":"When platelets fail: a case of active gastrointestinal bleeding in immune thrombocytopenia","volume":"17","author":"Malik","year":"2025","journal-title":"Cureus"},{"key":"10.1016\/j.cca.2026.121171_bb0025","doi-asserted-by":"crossref","DOI":"10.3390\/jcm6020016","article-title":"Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)","volume":"6","author":"Zufferey","year":"2017","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0030","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMra010501","article-title":"Medical progress: immune thrombocytopenic purpura","volume":"346","author":"Cines","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0035","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1056\/NEJMcp1810479","article-title":"Immune thrombocytopenia","volume":"381","author":"Cooper","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0040","author":"Medicine"},{"key":"10.1016\/j.cca.2026.121171_bb0045","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/jth.14227","article-title":"Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults","volume":"16","author":"Piel-Julian","year":"2018","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0050","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1182\/blood-2018-99-118403","article-title":"Antiplatelet antibody testing in immune thrombocytopenia and Evans syndrome: longitudinal serologic evolution and relation to clinical features","volume":"132","author":"Al-Samkari","year":"2018","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jcm9123851","article-title":"Evans' syndrome: from diagnosis to treatment","volume":"9","author":"Audia","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2025.101322","article-title":"Evans syndrome revisited","volume":"74","author":"Jiang","year":"2025","journal-title":"Blood Rev."},{"key":"10.1016\/j.cca.2026.121171_bb0065","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1182\/blood.V94.3.909.415k02_909_913","article-title":"The incidence of idiopathic thrombocytopenic Purpura in adults increases with age","volume":"94","author":"Frederiksen","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0070","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1016\/j.hoc.2009.08.004","article-title":"Chronic immune thrombocytopenia in adults: epidemiology and clinical presentation","volume":"23","author":"Fogarty","year":"2009","journal-title":"Hematol. Oncol. Clin. North Am."},{"key":"10.1016\/j.cca.2026.121171_bb0075","series-title":"Immune Thrombocytopenia (ITP): Comprehensive Insights into Pathophysiology, Diagnosis, and Management, E-book","author":"Eugenia","year":"2024"},{"key":"10.1016\/j.cca.2026.121171_bb0080","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.3324\/haematol.2021.279513","article-title":"Diagnosis of immune thrombocytopenia, including secondary forms, and selection of second-line treatment","volume":"107","author":"Bussel","year":"2022","journal-title":"Haematologica"},{"key":"10.1016\/j.cca.2026.121171_bb0085","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1182\/blood.V98.6.1760","article-title":"Antiphospholipid antibodies and antiphospholipid syndrome in patients presenting with immune thrombocytopenic purpura: a prospective cohort study","volume":"98","author":"Diz-K\u00fc\u00e7\u00fckkaya","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0090","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/MOH.0b013e3282ab9904","article-title":"Secondary immune thrombocytopenic purpura","volume":"14","author":"Liebman","year":"2007","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0095","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ejim.2022.11.022","article-title":"Current approaches for the diagnosis and management of immune thrombocytopenia","volume":"108","author":"Anat","year":"2023","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0100","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1080\/09537100500438057","article-title":"Helicobacter pylori-associated immune thrombocytopenia","volume":"17","author":"Franchini","year":"2006","journal-title":"Platelets"},{"key":"10.1016\/j.cca.2026.121171_bb0105","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.hoc.2009.09.003","article-title":"The immune thrombocytopenia syndrome: a disorder of diverse pathogenesis and clinical presentation","volume":"23","author":"Cines","year":"2009","journal-title":"Hematol. Oncol. Clin. North Am."},{"key":"10.1016\/j.cca.2026.121171_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jcm9072212","article-title":"Pathophysiology and diagnosis of drug-induced immune thrombocytopenia","volume":"9","author":"Vayne","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25042163","article-title":"Current understanding of immune thrombocytopenia: a review of pathogenesis and treatment options","volume":"25","author":"Mititelu","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cca.2026.121171_bb0120","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1055\/s-0039-1678732","article-title":"Pathophysiology of autoimmune thrombocytopenia: current insight with a focus on thrombopoiesis","volume":"39","author":"Marini","year":"2019","journal-title":"Hamostaseologie"},{"key":"10.1016\/j.cca.2026.121171_bb0125","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/MOH.0000000000000612","article-title":"An update on the pathophysiology of immune thrombocytopenia","volume":"27","author":"Semple","year":"2020","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0130","doi-asserted-by":"crossref","DOI":"10.1186\/s13045-017-0413-3","article-title":"Platelet desialylation correlates with efficacy of first-line therapies for immune thrombocytopenia","volume":"10","author":"Tao","year":"2017","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.cca.2026.121171_bb0135","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/bjh.15404","article-title":"Detection of platelet autoantibodies to identify immune thrombocytopenia: state of the art","volume":"182","author":"Porcelijn","year":"2018","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0140","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3390\/hematolrep16020021","article-title":"Pathophysiology, clinical manifestations and diagnosis of immune thrombocytopenia: contextualization from a historical perspective","volume":"16","author":"Mart\u00ednez-Carballeira","year":"2024","journal-title":"Hematol. Rep."},{"key":"10.1016\/j.cca.2026.121171_bb0145","article-title":"Desialylation is a mechanism of fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia","volume":"6","author":"Li","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cca.2026.121171_bb0150","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1016\/j.jtha.2025.05.024","article-title":"Clinical evidence for antiglycoprotein IIbIIIa antibody-induced platelet desialylation in primary immune thrombocytopenia","volume":"23","author":"Schramm","year":"2025","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0155","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1600-0609.2011.01718.x","article-title":"Autoantibody-mediated complement activation on platelets is a common finding in patients with immune thrombocytopenic purpura (ITP)","volume":"88","author":"Najaoui","year":"2012","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0160","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1182\/bloodadvances.2021004822","article-title":"Anti-glycoprotein antibodies and sequestration pattern of indium-labeled platelets in immune thrombocytopenia","volume":"6","author":"Amini","year":"2022","journal-title":"Blood Adv."},{"key":"10.1016\/j.cca.2026.121171_bb0165","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/bjh.12480","article-title":"Cellular immune dysfunction in immune thrombocytopenia (ITP)","volume":"163","author":"Mckenzie","year":"2013","journal-title":"Br. J. Haematol."},{"issue":"1","key":"10.1016\/j.cca.2026.121171_bb0170","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s44337-024-00040-8","article-title":"Immune thrombocytopenia: a review of pathogenesis and current treatment","volume":"1","author":"Yan","year":"2024","journal-title":"Discov. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtauto.2025.100309","article-title":"When the victim becomes the villain: platelets as drivers of immune dysregulation in ITP","volume":"11","author":"Farhid","year":"2025","journal-title":"J. Transl. Autoimmun."},{"key":"10.1016\/j.cca.2026.121171_bb0180","doi-asserted-by":"crossref","first-page":"E574","DOI":"10.1097\/HS9.0000000000000574","article-title":"Immune thrombocytopenia: recent advances in pathogenesis and treatments","volume":"5","author":"Audia","year":"2021","journal-title":"HemaSphere"},{"key":"10.1016\/j.cca.2026.121171_bb0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050909","article-title":"The ratio of Treg\/Th17 cells correlates with the disease activity of primary immune thrombocytopenia","volume":"7","author":"Ji","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.cca.2026.121171_bb0190","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1600-0609.2006.00780.x","article-title":"Abnormality of CD4(+)CD25(+) regulatory T cells in idiopathic thrombocytopenic purpura","volume":"78","author":"Liu","year":"2007","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103820","article-title":"Recent advances in the mechanisms and treatment of immune thrombocytopenia","volume":"76","author":"Provan","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.cca.2026.121171_bb0200","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1182\/blood-2002-05-1475","article-title":"Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro","volume":"102","author":"Chang","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0205","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.autrev.2017.04.012","article-title":"Pathogenesis of immune thrombocytopenia","volume":"16","author":"Audia","year":"2017","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.cca.2026.121171_bb0210","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1499014","article-title":"The function of T cells in immune thrombocytopenia","volume":"16","author":"Bu","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cca.2026.121171_bb0215","doi-asserted-by":"crossref","DOI":"10.1007\/s11033-025-10363-z","article-title":"The intersection of epigenetics and immune thrombocytopenia: new insights into disease mechanisms and treatments","volume":"52","author":"Zhou","year":"2025","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.cca.2026.121171_bb0220","first-page":"152","article-title":"In vitro generated megakaryocytes for the detection of human platelet antigen-specific alloantibodies","volume":"52","author":"Uzun","year":"2025","journal-title":"Transfus. Med. Hemotherapy"},{"key":"10.1016\/j.cca.2026.121171_bb0225","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1016\/j.htct.2024.06.004","article-title":"Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-lx","volume":"46","author":"Costa","year":"2024","journal-title":"Hematol. Transfus. Cell Ther."},{"key":"10.1016\/j.cca.2026.121171_bb0230","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.htct.2020.12.008","article-title":"Platelet antibodies identification: comparison between two laboratory tests","volume":"44","author":"Dutra","year":"2022","journal-title":"Hematol. Transfus. Cell Ther."},{"key":"10.1016\/j.cca.2026.121171_bb0235","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1034\/j.1600-0609.2003.00033.x","article-title":"Pseudothrombocytopenia as a pitfall in the treatment of essential thrombocythemia","volume":"70","author":"Braester","year":"2003","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0240","first-page":"1","article-title":"Idiopathic thrombocytopenia with Iron deficiency Anemia","volume":"6","author":"Ibrahim","year":"2013","journal-title":"Clin. Med. Insights"},{"key":"10.1016\/j.cca.2026.121171_bb0245","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00003246-197907000-00002","article-title":"Severe thrombocytopenia probably due to acute folic acid deficiency","volume":"7","author":"Mant","year":"1979","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.cca.2026.121171_bb0250","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/2249-4863.152276","article-title":"Vitamin B12 and vitamin D deficiencies: an unusual cause of fever, severe Hemolytic Anemia and thrombocytopenia","volume":"4","author":"Mishra","year":"2015","journal-title":"J. Fam. Med. Prim. Care"},{"key":"10.1016\/j.cca.2026.121171_bb0255","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1365-2141.2009.07600.x","article-title":"Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in haematology","volume":"145","author":"Levi","year":"2009","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0260","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1182\/blood.V88.1.3.3","article-title":"Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology","volume":"88","author":"George","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0265","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1046\/j.1365-2257.2000.00340.x","article-title":"The management of isolated thrombocytopenia in Chinese adults: does bone marrow examination have a role at presentation?","volume":"22","author":"Mak","year":"2000","journal-title":"Clin. Lab. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0270","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/107602960200800110","article-title":"The role of the bone marrow examination in the diagnosis of immune thrombocytopenic purpura: case series and literature review","volume":"8","author":"Jubelirer","year":"2002","journal-title":"Clin. Appl. Thromb. Hemost."},{"key":"10.1016\/j.cca.2026.121171_bb0275","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1046\/j.1365-2141.2003.04131.x","article-title":"British Committee for Standards in haematology general haematology task force, guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy","volume":"120","year":"2003","journal-title":"Br. J. Haematol."},{"issue":"Suppl. 5","key":"10.1016\/j.cca.2026.121171_bb0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000492187","article-title":"Immune thrombocytopenia - current diagnostics and therapy: recommendations of a joint working group of DGHO, \u00d6GHO, SGH, GPOH, and DGTI","volume":"41","author":"Matzdorff","year":"2018","journal-title":"Oncol. Res. Treat."},{"issue":"Suppl. 2","key":"10.1016\/j.cca.2026.121171_bb0285","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1159\/000529662","article-title":"Expert report on immune thrombocytopenia: current diagnostics and treatment - recommendations from an expert group from Austria, Germany, and Switzerland","volume":"46","author":"Matzdorff","year":"2023","journal-title":"Oncol. Res. Treat."},{"key":"10.1016\/j.cca.2026.121171_bb0290","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1182\/asheducation-2008.1.212","article-title":"Viral-associated immune thrombocytopenic Purpura","volume":"2008","author":"Liebman","year":"2008","journal-title":"Hematology"},{"key":"10.1016\/j.cca.2026.121171_bb0295","doi-asserted-by":"crossref","first-page":"3780","DOI":"10.1182\/bloodadvances.2019000812","article-title":"Updated international consensus report on the investigation and management of primary immune thrombocytopenia","volume":"3","author":"Provan","year":"2019","journal-title":"Blood Adv."},{"key":"10.1016\/j.cca.2026.121171_bb0300","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1182\/blood-2008-07-167155","article-title":"Effects of eradication of helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review","volume":"113","author":"Stasi","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0305","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1365-2141.2008.07228.x","article-title":"Antiphospholipid antibodies in adults with immune thrombocytopenic purpura","volume":"142","author":"Pierrot-Deseilligny Despujol","year":"2008","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0310","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/bjh.12318","article-title":"Thrombotic risk in patients with immune thrombocytopenia and its association with antiphospholipid antibodies","volume":"161","author":"Kim","year":"2013","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0315","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/ajh.24702","article-title":"Newly diagnosed immune thrombocytopenia adults: clinical epidemiology, exposure to treatments, and evolution. Results of the CARMEN multicenter prospective cohort","volume":"92","author":"Moulis","year":"2017","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0320","doi-asserted-by":"crossref","DOI":"10.1080\/16078454.2025.2551454","article-title":"Antinuclear antibody positive in patients with primary immune thrombocytopenia: incidence and risk prediction of developing autoimmune diseases","volume":"30","author":"Liang","year":"2025","journal-title":"Hematology"},{"key":"10.1016\/j.cca.2026.121171_bb0325","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.hoc.2009.08.003","article-title":"Thyroid disease in patients with immune thrombocytopenia","volume":"23","author":"Cheung","year":"2009","journal-title":"Hematol. Oncol. Clin. North Am."},{"key":"10.1016\/j.cca.2026.121171_bb0330","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/MBC.0000000000001144","article-title":"Primary immune thrombocytopenia: a \u2018diagnosis of exclusion\u2019?","volume":"33","author":"Visweshwar","year":"2022","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.cca.2026.121171_bb0335","first-page":"288","article-title":"Thrombocytopenia: evaluation and management","volume":"106","author":"Gauer","year":"2022","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.cca.2026.121171_bb0340","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16081462","article-title":"The challenge for a correct diagnosis of refractory thrombocytopenia: ITP or MDS with isolated thrombocytopenia?","volume":"16","author":"Kosmidou","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cca.2026.121171_bb0345","first-page":"588","article-title":"The differential diagnosis of Thromobocytopenia","volume":"122","author":"Miesbach","year":"2025","journal-title":"Dtsch. Arztebl. Int."},{"key":"10.1016\/j.cca.2026.121171_bb0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12185-023-03672-1","article-title":"Reference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 Edition","volume":"119","author":"Kashiwagi","year":"2024","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0355","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0295011","article-title":"The diagnostic accuracy of mean platelet volume in differentiating immune thrombocytopenic purpura from hypo-productive thrombocytopenia: a systematic review and meta-analysis","volume":"18","author":"Walle","year":"2023","journal-title":"PloS One"},{"key":"10.1016\/j.cca.2026.121171_bb0360","doi-asserted-by":"crossref","DOI":"10.1080\/09537104.2025.2467383","article-title":"From reticulated platelets to immature platelet fraction: structure, function, and clinical applications","volume":"36","author":"Zhang","year":"2025","journal-title":"Platelets"},{"key":"10.1016\/j.cca.2026.121171_bb0365","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/jth.14419","article-title":"The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test","volume":"17","author":"Vrbensky","year":"2019","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0370","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1182\/asheducation-2018.1.561","article-title":"How do we diagnose immune thrombocytopenia in 2018?","volume":"2018","author":"Kelton","year":"2018","journal-title":"Hematol. Am. Soc. Hematol. Educ. Progr."},{"key":"10.1016\/j.cca.2026.121171_bb0375","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1055\/s-0039-1678739","article-title":"Diagnosing immune thrombocytopenia","volume":"39","author":"Sachs","year":"2019","journal-title":"Hamostaseologie"},{"key":"10.1016\/j.cca.2026.121171_bb0380","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1515\/labmed-2020-0012","article-title":"Platelet antibodies in immune thrombocytopenia and related conditions","volume":"44","author":"Kiefel","year":"2020","journal-title":"J. Lab. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0385","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.jtha.2023.12.030","article-title":"Recombinantly expressed tagged SUrface protein (RETSUP) assay: a new diagnostic system for the detection of antibodies to platelets","volume":"22","author":"Weber","year":"2024","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0390","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1182\/blood.V59.1.23.23","article-title":"Specificity of autoantibodies in autoimmune thrombocytopenia","volume":"59","author":"van Leeuwen","year":"1982","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0395","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1182\/blood.V83.4.1024.1024","article-title":"Spectrum of Ig classes, specificities, and titers of serum antiglycoproteins in chronic idiopathic thrombocytopenic purpura","volume":"83","author":"He","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0400","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/vox.12085","article-title":"Human platelet antigens - 2013","volume":"106","author":"Curtis","year":"2014","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0405","first-page":"186","article-title":"The molecular biology of platelet membrane proteins","volume":"27","author":"Bennett","year":"1990","journal-title":"Semin. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0410","doi-asserted-by":"crossref","first-page":"891","DOI":"10.12669\/pjms.293.3497","article-title":"Moinuddin, platelet receptors; an instrumental of platelet physiology","volume":"29","author":"Saboor","year":"2013","journal-title":"Pak. J. Med. Sci."},{"key":"10.1016\/j.cca.2026.121171_bb0415","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0092-8674(00)80983-6","article-title":"Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor","volume":"84","author":"Savage","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.cca.2026.121171_bb0420","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1182\/blood.V66.3.724.724","article-title":"Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets","volume":"66","author":"Plow","year":"1985","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0425","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1182\/blood.V98.6.1819","article-title":"Platelet-associated anti-GPIIb-IIIa autoantibodies in chronic immune thrombocytopenic purpura recognizing epitopes close to the ligand-binding site of glycoprotein (GP) IIb","volume":"98","author":"Kosugi","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0430","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1182\/blood-2012-02-409995","article-title":"Recognition of highly restricted regions in the \u03b2-propeller domain of \u03b1IIb by platelet-associated anti-\u03b1IIb\u03b23 autoantibodies in primary immune thrombocytopenia","volume":"120","author":"Kiyomizu","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0435","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0301-4622(03)00111-X","article-title":"The disulfide-rich region of platelet glycoprotein (GP) IIIa contains hydrophilic peptide sequences that bind anti-GPIIIa autoantibodies from patients with immune thrombocytopenic purpura (ITP)","volume":"105","author":"Beardsley","year":"2003","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.cca.2026.121171_bb0440","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1172\/JCI111587","article-title":"Platelet membrane glycoprotein IIIa contains target antigens that bind anti-platelet antibodies in immune thrombocytopenias","volume":"74","author":"Beardsley","year":"1984","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cca.2026.121171_bb0445","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1182\/blood-2006-05-024091","article-title":"Glycoprotein Ib\u03b1 forms disulfide bonds with 2 glycoprotein Ib\u03b2 subunits in the resting platelet","volume":"109","author":"Luo","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0450","doi-asserted-by":"crossref","DOI":"10.1182\/blood-2012-04-416594","article-title":"The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways","volume":"120","author":"Burkhart","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0455","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1055\/s-0037-1616216","article-title":"The vascular biology of the glycoprotein Ib-IX-V complex","volume":"86","author":"Berndt","year":"2001","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0460","doi-asserted-by":"crossref","first-page":"3789","DOI":"10.1182\/blood.V86.10.3789.bloodjournal86103789","article-title":"Extracellular epitopes of platelet glycoprotein Ib alpha reactive with serum antibodies from patients with chronic idiopathic thrombocytopenic purpura","volume":"86","author":"He","year":"1995","journal-title":"Blood"},{"issue":"Suppl. 2","key":"10.1016\/j.cca.2026.121171_bb0465","article-title":"Platelet adhesion to collagen","volume":"127","author":"Nuyttens","year":"2011","journal-title":"Thromb. Res."},{"key":"10.1016\/j.cca.2026.121171_bb0470","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1182\/blood.V89.6.1939","article-title":"Hereditary variation in platelet integrin \u03b12\u03b21 density is associated with two silent polymorphisms in the \u03b12 gene coding sequence","volume":"89","author":"Kunicki","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0475","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/s-0043-1768935","article-title":"The role of CD36\/GPIV in platelet biology","volume":"50","author":"Bendas","year":"2024","journal-title":"Semin. Thromb. Hemost."},{"key":"10.1016\/j.cca.2026.121171_bb0480","doi-asserted-by":"crossref","first-page":"18244","DOI":"10.1016\/S0021-9258(19)37179-0","article-title":"CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction","volume":"267","author":"Leung","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cca.2026.121171_bb0485","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.272re3","article-title":"CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior","volume":"2","author":"Silverstein","year":"2009","journal-title":"Sci. Signal."},{"key":"10.1016\/j.cca.2026.121171_bb0490","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1182\/blood-2002-12-3882","article-title":"Platelet-collagen interaction: is GPVI the central receptor?","volume":"102","author":"Nieswandt","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0495","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.thromres.2004.06.046","article-title":"Platelet glycoprotein VI: its structure and function","volume":"114","author":"Moroi","year":"2004","journal-title":"Thromb. Res."},{"key":"10.1016\/j.cca.2026.121171_bb0500","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0037-1963(00)90102-1","article-title":"Autoantibodies and autoantigens in chronic immune thrombocytopenic purpura","volume":"37","author":"McMillan","year":"2000","journal-title":"Semin. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0505","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1532\/IJH97.04193","article-title":"Autoantigenic epitopes on platelet glycoproteins","volume":"81","author":"Tomiyama","year":"2005","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0510","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1182\/bloodadvances.2019000868","article-title":"A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia","volume":"4","author":"Al-Samkari","year":"2020","journal-title":"Blood Adv."},{"key":"10.1016\/j.cca.2026.121171_bb0515","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1016\/j.jtha.2025.02.016","article-title":"Platelet autoantibodies have an impact on the platelet count in patients","volume":"23","author":"Sachs","year":"2025","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0520","first-page":"17","article-title":"Anti-platelet autoantibodies from ITP patients recognize an epitope in GPIIb\/IIIa deduced by complementary hydropathy","volume":"75","author":"De Souza","year":"1992","journal-title":"Immunology"},{"key":"10.1016\/j.cca.2026.121171_bb0525","series-title":"[Glykoprotein V-spezifische Thrombozytenantik\u00f6rper bei Patienten mit Immunthrombozytopenie (ITP)], Justus-Liebig-Universit\u00e4t Gie\u00dfen","author":"Stoy","year":"2013"},{"key":"10.1016\/j.cca.2026.121171_bb0530","first-page":"2129","article-title":"Comparative studies on an autoantigen in ITP and the baka alloantigen on platelet membrane glycoprotein IIb","volume":"30","author":"Take","year":"1989","journal-title":"Rinsho Ketsueki"},{"issue":"2025","key":"10.1016\/j.cca.2026.121171_bb0535","first-page":"1","article-title":"Diagnosis and Management of Fetal and Neonatal Alloimmune Thrombocytopenia: An Update","volume":"52","author":"Sachs","year":"2025","journal-title":"Transfus. Med. Hemother."},{"key":"10.1016\/j.cca.2026.121171_bb0540","doi-asserted-by":"crossref","DOI":"10.3390\/genes16060705","article-title":"Human CD36: gene regulation, protein function, and its role in atherosclerosis pathogenesis","volume":"16","author":"Rac","year":"2025","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.cca.2026.121171_bb0545","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1046\/j.1365-2141.1999.01218.x","article-title":"A prospective study of protein-specific assays used to investigate idiopathic thrombocytopenic purpura","volume":"104","author":"Warner","year":"1999","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0550","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1182\/blood.V70.4.1040.1040","article-title":"Platelet-associated and plasma anti-glycoprotein autoantibodies in chronic ITP","volume":"70","author":"McMillan","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0555","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1007\/s002770050173","article-title":"Platelet autoantibodies (IgG, IgM, IgA) against glycoproteins IIb\/IIIa and Ib\/IX in patients with thrombocytopenia","volume":"72","author":"Kiefel","year":"1996","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0560","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1423-0410.1982.tb00012.x","article-title":"Elution of granulocyte and platelet antibodies","volume":"43","author":"Helmerhorst","year":"1982","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0565","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1423-0410.1990.tb05004.x","article-title":"New method for the elution of platelet antibodies","volume":"58","author":"Pujol","year":"1990","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0570","doi-asserted-by":"crossref","DOI":"10.21769\/BioProtoc.4562","article-title":"Human auto-IgG purification from high volume serum sample by protein G affinity purification","volume":"12","author":"Sensi","year":"2022","journal-title":"Bio-Protocol"},{"key":"10.1016\/j.cca.2026.121171_bb0575","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1182\/blood.V50.2.317.317","article-title":"Platelet-associated IgG in immune thrombocytopenic Purpura","volume":"50","author":"Luiken","year":"1977","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0580","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1055\/s-0038-1642682","article-title":"The serological investigation of patients with autoimmune thrombocytopenia","volume":"74","author":"Kelton","year":"1995","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0585","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1182\/blood.V37.3.316.316","article-title":"Immunoglobulins associated with human platelets","volume":"37","author":"McMillan","year":"1971","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0590","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1056\/NEJM197501302920503","article-title":"Quantitative determination of antibody in idiopathic thrombocytopenic purpura","volume":"292","author":"Dixon","year":"1975","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0595","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajh.2830180102","article-title":"Comparison of the measurement of surface or total platelet-associated IgG in the diagnosis of immune thrombocytopenia","volume":"18","author":"Kelton","year":"1985","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0600","first-page":"639","article-title":"A solid-phase radioimmunoassay for bound anti-platelet antibody: studies on 45 patients with autoimmune platelet disorders","volume":"94","author":"Hymes","year":"1979","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0605","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1182\/blood.V76.5.859.859","article-title":"Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the origin of \u03b1-granule proteins","volume":"76","author":"George","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0610","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-2141.1980.tb05942.x","article-title":"The clinical significance of platelet-associated IgG: a study on 298 patients with various disorders","volume":"46","author":"Mueller-Eckhardt","year":"1980","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0615","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1365-2141.1978.tb01089.x","article-title":"A simple immunofluorescence test for the detection of platelet antibodies","volume":"39","author":"von dem Borne","year":"1978","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0620","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1423-0410.1981.tb00667.x","article-title":"Modification of the platelet suspension immunofluorescence test","volume":"40","author":"Andersen","year":"1981","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0625","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1055\/s-0037-1614115","article-title":"Quantification of platelet-associated IgG for differential diagnosis of patients with thrombocytopenia","volume":"84","author":"Hagenstrom","year":"2000","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0630","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/BF00320318","article-title":"The platelet adhesion immunofluorescence test: a modification of the platelet suspension immunofluorescence test","volume":"43","author":"Schneider","year":"1981","journal-title":"Blut"},{"key":"10.1016\/j.cca.2026.121171_bb0635","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/bjh.15187","article-title":"Detection of anti-platelet antibodies in immune thrombocytopenia by flow cytometry","volume":"184","author":"Teraz-Orosz","year":"2019","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0640","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1515\/cclm-2014-1037","article-title":"Comparison of the bead-based simultaneous analysis of specific platelet antibodies assay (SASPA) and Pak lx Luminex technology with the monoclonal antibody immobilization of platelet antigens assay (MAIPA) to detect platelet alloantibodies","volume":"53","author":"Rockenbauer","year":"2015","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.transci.2019.102705","article-title":"Progress and development of platelet antibody detection","volume":"59","author":"Porcelijn","year":"2020","journal-title":"Transfus. Apher. Sci."},{"key":"10.1016\/j.cca.2026.121171_bb0650","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1182\/blood.V64.1.156.156","article-title":"Autoantibodies against platelet glycoprotein Ib in patients with chronic immune thrombocytopenic Purpura","volume":"64","author":"Woods","year":"1984","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0655","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1182\/blood.V63.2.368.368","article-title":"Autoantibodies against the platelet glycoprotein Ilb\/IIIa complex in patients with chronic ITP","volume":"63","author":"Woods","year":"1984","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0660","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1182\/blood.V73.6.1561.1561","article-title":"Cyclic thrombocytopenia of apparent autoimmune etiology","volume":"73","author":"Menitove","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0665","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1423-0410.2006.00839.x","article-title":"A novel antigen-specific capture assay for the detection of platelet antibodies and HPA-1a phenotyping","volume":"91","author":"Meyer","year":"2006","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0670","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.4049\/jimmunol.168.7.3675","article-title":"Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura","volume":"168","author":"Kuwana","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.cca.2026.121171_bb0675","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S0002-9343(02)01522-X","article-title":"Detection of circulating B cells secreting platelet-specific autoantibody is useful in the diagnosis of autoimmune thrombocytopenia","volume":"114","author":"Kuwana","year":"2003","journal-title":"Am. J. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0680","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086943","article-title":"Detection of circulating B cells producing anti-GPIb autoantibodies in patients with immune thrombocytopenia","volume":"9","author":"Kuwana","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.cca.2026.121171_bb0685","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1179\/1607845412Y.0000000014","article-title":"The clinical significance of circulating B cells secreting anti-glycoprotein IIb\/IIIa antibody and platelet glycoprotein IIb\/IIIa in patients with primary immune thrombocytopenia","volume":"17","author":"Chen","year":"2012","journal-title":"Hematology"},{"key":"10.1016\/j.cca.2026.121171_bb0690","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1182\/blood.V70.6.1722.1722","article-title":"Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies","volume":"70","author":"Kiefel","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0695","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1365-3148.1992.tb00153.x","article-title":"The MAIPA assay and its applications in immunohaematology","volume":"2","author":"Kiefel","year":"1992","journal-title":"Transfus. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0700","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1423-0410.2007.00989.x","article-title":"A modified rapid monoclonal antibody-specific immobilization of platelet antigen assay for the detection of human platelet antigen (HPA) antibodies: a multicentre evaluation","volume":"93","author":"Campbell","year":"2007","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0705","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.cca.2012.10.035","article-title":"Detection of autoantibodies against platelet glycoproteins in patients with immune thrombocytopenic purpura by flow cytometric immunobead array","volume":"415","author":"He","year":"2013","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cca.2026.121171_bb0710","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/j.1365-2141.2004.05233.x","article-title":"A novel method for simultaneous analysis of specific platelet antibodies: SASPA","volume":"127","author":"Nguyen","year":"2004","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0715","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1111\/trf.14122","article-title":"Detection and identification of platelet antibodies using a sensitive multiplex assay system-platelet antibody bead array","volume":"57","author":"Metzner","year":"2017","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0720","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1172\/JCI110780","article-title":"Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood","volume":"71","author":"Montgomery","year":"1983","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cca.2026.121171_bb0725","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/j.1537-2995.2008.02065.x","article-title":"Low-avidity HPA-1a alloantibodies in severe neonatal alloimmune thrombocytopenia are detectable with surface plasmon resonance technology","volume":"49","author":"Santoso","year":"2009","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0730","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.tmrv.2020.09.003","article-title":"Evolution and utility of antiplatelet autoantibody testing in patients with immune thrombocytopenia","volume":"34","author":"Porcelijn","year":"2020","journal-title":"Transfus. Med. Rev."},{"key":"10.1016\/j.cca.2026.121171_bb0735","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/vox.12118","article-title":"A new transfectant panel cell line-based MoAb-independent antigen capture assay system for detection of CD36 antibody","volume":"106","author":"Amakishi","year":"2014","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0740","doi-asserted-by":"crossref","DOI":"10.21037\/aob-21-48","article-title":"A narrative review on progress and development of anti-CD36 antibody detection","volume":"6","author":"Xu","year":"2021","journal-title":"Ann. Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0745","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/01.mbc.0000233371.26228.44","article-title":"Identification of human platelet glycoprotein VI-specific IgG autoantibody and its fragments","volume":"17","author":"Chu","year":"2006","journal-title":"Blood Coagul. Fibrinolysis"},{"key":"10.1016\/j.cca.2026.121171_bb0750","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1538-7836.2012.04664.x","article-title":"Recommendations for the implementation of platelet autoantibody testing in clinical trials of immune thrombocytopenia","volume":"10","author":"Arnold","year":"2012","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0755","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1111\/j.1537-2995.2011.03171.x","article-title":"Low-avidity anti-HPA-1a alloantibodies are capable of antigen-positive platelet destruction in the NOD\/SCID mouse model of alloimmune thrombocytopenia","volume":"51","author":"Bakchoul","year":"2011","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0760","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.cca.2016.04.031","article-title":"Simultaneous detection of platelet-specific antibodies based on a photonic crystal-encoded suspension array","volume":"458","author":"Kong","year":"2016","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cca.2026.121171_bb0765","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1537-2995.2008.02000.x","article-title":"Establishment of a novel method for detecting nak antibodies by using a panel cell line","volume":"49","author":"Hayashi","year":"2009","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0770","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-3148.2010.01064.x","article-title":"Establishment of a cell line panel as an alternative source of platelet antigens for a screening assay of anti-human platelet antibodies","volume":"21","author":"Hayashi","year":"2011","journal-title":"Transfus. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0775","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/s12185-011-0772-4","article-title":"Establishment of a cell line panel for the detection of antibodies against human platelet antigen 4b","volume":"93","author":"Hayashi","year":"2011","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0780","article-title":"Detection of anti-human platelet antibodies against integrin \u03b12\u03b21 using cell lines","volume":"12","author":"Hayashi","year":"2014","journal-title":"Blood Transfus."},{"key":"10.1016\/j.cca.2026.121171_bb0785","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1182\/blood.2019002225","article-title":"Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies","volume":"134","author":"Zhang","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0790","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.cca.2020.09.029","article-title":"A novel method to detect autoantibodies against platelets in patients with immune thrombocytopenia","volume":"511","author":"He","year":"2020","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cca.2026.121171_bb0795","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1182\/blood.V92.6.2053","article-title":"A recombinant soluble form of the integrin \u03b1IIb\u03b23 (GPIIb-IIIa) assumes an active, ligand-binding conformation and is recognized by GPIIb-IIIa\u2013specific monoclonal, Allo-, auto-, and drug-dependent platelet antibodies","volume":"92","author":"Peterson","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0800","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.3324\/haematol.2018.211086","article-title":"Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia","volume":"104","author":"Vollenberg","year":"2019","journal-title":"Haematologica"},{"key":"10.1016\/j.cca.2026.121171_bb0805","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/trf.14369","article-title":"Fetal\/neonatal alloimmune thrombocytopenia due to anti-CD36 antibodies: antibody evaluations by CD36-transfected cell lines","volume":"58","author":"Lin","year":"2018","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0810","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1365-3148.1991.tb00026.x","article-title":"Evaluation of a solid phase red cell adherence technique for platelet antibody screening","volume":"1","author":"Lown","year":"1991","journal-title":"Transfus. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0815","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1182\/blood.V89.3.1112","article-title":"Platelet antibody testing in idiopathic thrombocytopenic Purpura","volume":"89","author":"Raife","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0820","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1046\/j.1365-3148.1999.009001063.x","article-title":"Evaluation of an enzyme-linked immunosorbent assay kit (GTI PakPlus\u00ae) for the detection of antibodies against human platelet antigens","volume":"9","author":"Lucas","year":"1999","journal-title":"Transfus. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0825","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/ajh.20309","article-title":"Prospective evaluation of a new platelet glycoprotein (GP)-specific assay (PakAuto) in the diagnosis of autoimmune thrombocytopenia (AITP)","volume":"78","author":"Davoren","year":"2005","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0830","doi-asserted-by":"crossref","DOI":"10.1007\/s10238-025-01831-8","article-title":"Comparative analysis of MAIPA assay and PakAuto assay for the diagnosis of primary immune thrombocytopenia","volume":"25","author":"Chen","year":"2025","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0835","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1111\/trf.12509","article-title":"A new bead-based human platelet antigen antibodies detection assay versus the monoclonal antibody immobilization of platelet antigens assay","volume":"54","author":"Porcelijn","year":"2014","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0840","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1423-0410.1981.tb01007.x","article-title":"Detection of platelet antibodies by a newly developed mixed agglutination with platelets","volume":"41","author":"Shibata","year":"1981","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0845","first-page":"1046","article-title":"Attempt to improve the diagnosis of immune thrombocytopenia by combined use of two different platelet autoantibodies assays (PAIgG and MACE)","volume":"87","author":"Fabris","year":"2002","journal-title":"Haematologica"},{"key":"10.1016\/j.cca.2026.121171_bb0850","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1365-2141.1991.tb04530.x","article-title":"Autoantibodies against platelet glycoprotein Ib\/IX: a frequent finding in autoimmune thrombocytopenic purpura","volume":"79","author":"Kiefel","year":"1991","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0855","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1182\/blood.V88.1.194.194","article-title":"Prospective evaluation of the clinical usefulness of an antigen-specific assay (MAIPA) in idiopathic thrombocytopenic purpura and other immune thrombocytopenias","volume":"88","author":"Brighton","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb0860","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1046\/j.1538-7836.2003.00091.x","article-title":"Prospective evaluation of the immunobead assay for the diagnosis of adult chronic immune thrombocytopenic purpura (ITP)","volume":"1","author":"McMillan","year":"2003","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0865","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1111\/j.1537-2995.2010.02610.x","article-title":"The detection of platelet antibodies by simultaneous analysis of specific platelet antibodies and the monoclonal antibody-specific immobilization of platelet antigens: an interlaboratory comparison","volume":"50","author":"Nguyen","year":"2010","journal-title":"Transfusion"},{"key":"10.1016\/j.cca.2026.121171_bb0870","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1111\/j.1538-7836.2006.02091.x","article-title":"Preliminary laboratory based diagnostic criteria for immune thrombocytopenic purpura: evaluation by multi-center prospective study","volume":"4","author":"Kuwana","year":"2006","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0875","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1365-2141.1997.d01-1995.x","article-title":"Comparison of the direct platelet immunofluorescence test (direct PIFT) with a modified direct monoclonal antibody-specific immobilization of platelet antigens (direct MAIPA) in detection of platelet-associated IgG","volume":"96","author":"Joutsi","year":"1997","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0880","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/bjh.17566","article-title":"Performance characteristics of platelet autoantibody testing for the diagnosis of immune thrombocytopenia using strict clinical criteria","volume":"194","author":"Gabe","year":"2021","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0885","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-3148.1997.d01-15.x","article-title":"A comparison of monoclonal antibody immobilization of platelet antigen (MAIPA) and immunobead methods for detection of GPIIb\/IIIa antiplatelet antibodies in immune thrombocytopenic purpura","volume":"7","author":"Crossley","year":"1997","journal-title":"Transfus. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0890","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1423-0410.2007.00943.x","article-title":"Monoclonal platelet antigen capture assays (MAIPA) and reagents: a statement","volume":"93","author":"Kaplan","year":"2007","journal-title":"Vox Sang."},{"key":"10.1016\/j.cca.2026.121171_bb0895","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.pathol.2020.12.006","article-title":"Indirect detection of anti-platelet antibodies in immune thrombocytopenia","volume":"53","author":"Zheng","year":"2021","journal-title":"Pathology"},{"key":"10.1016\/j.cca.2026.121171_bb0900","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1309\/1QWTQFMF0Q9JEAGR","article-title":"Modification of solid phase red cell adherence assay for the detection of platelet antibodies in patients with thrombocytopenia","volume":"130","author":"Vongchan","year":"2008","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.cca.2026.121171_bb0905","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1055\/s-0038-1650702","article-title":"PAICA: a method for characterizing platelet-associated antibodies - its application to the study of idiopathic thrombocytopenic purpura and to the detection of platelet-bound c7E3","volume":"76","author":"Macchi","year":"1996","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb0910","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1093\/clinchem\/46.8.1037","article-title":"Interferences in immunoassay\u2014still a threat","volume":"46","author":"Kricka","year":"2000","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cca.2026.121171_bb0915","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1093\/clinchem\/48.11.2023","article-title":"Wrong biochemistry results: two case reports and observational study in 5310 patients on potentially misleading thyroid-stimulating hormone and gonadotropin immunoassay results","volume":"48","author":"Ismail","year":"2002","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cca.2026.121171_bb0920","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1097\/01.HS9.0000849444.77142.db","article-title":"P1647: contribution of next generation flow (NGF) cytometry in primary immune thrombocytopenia (ITP): utility for the differential diagnosis with myelodysplastic syndromes","volume":"6","author":"Gonzalez-Lopez","year":"2022","journal-title":"HemaSphere"},{"key":"10.1016\/j.cca.2026.121171_bb0925","first-page":"575","article-title":"Importance of immature platelet fraction as predictor of immune thrombocytopenic purpura, Pakistan","volume":"32","author":"Naz","year":"2016","journal-title":"J. Med. Sci."},{"key":"10.1016\/j.cca.2026.121171_bb0930","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.ejim.2006.03.006","article-title":"Measurement of reticulated platelets by simple flow cytometry: an indirect thrombocytopoietic marker","volume":"17","author":"Jim\u00e9nez","year":"2006","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0935","first-page":"451","article-title":"Immature platelet fraction: establishment of a reference interval and diagnostic measure for thrombocytopenia","volume":"30","author":"Jung","year":"2010","journal-title":"Korean J. Lab. Med."},{"key":"10.1016\/j.cca.2026.121171_bb0940","article-title":"Reticulated platelet count as a diagnostic tool in immune thrombocytopenia (ITP)","volume":"15","author":"Butt","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.cca.2026.121171_bb0945","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s12185-018-2445-z","article-title":"Chinese guidelines for treatment of adult primary immune thrombocytopenia","volume":"107","author":"Liu","year":"2018","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0950","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1080\/09537104.2019.1678118","article-title":"Immature platelet fraction related parameters in the differential diagnosis of thrombocytopenia","volume":"31","author":"Li","year":"2020","journal-title":"Platelets"},{"key":"10.1016\/j.cca.2026.121171_bb0955","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.thromres.2021.03.023","article-title":"Diagnostic characteristics of immature platelet fraction for the assessment of immune thrombocytopenia","volume":"202","author":"Pereira","year":"2021","journal-title":"Thromb. Res."},{"key":"10.1016\/j.cca.2026.121171_bb0960","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000019096","article-title":"Immature platelet fraction: a useful marker for identifying the cause of thrombocytopenia and predicting platelet recovery","volume":"99","author":"Jeon","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.cca.2026.121171_bb0965","first-page":"760","article-title":"Diagnostic Accuracy of Immature Platelet Fraction (IPF) to Differentiate Between Thrombocytopenia due to Peripheral Destruction <em>versus<\/em> Bone Marrow Failure","volume":"33","author":"Asghar","year":"2023","journal-title":"J. Coll. Physicians Surg. Pak."},{"key":"10.1016\/j.cca.2026.121171_bb0970","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1600-0609.2008.01156.x","article-title":"Aberrant increase in the immature platelet fraction in patients with myelodysplastic syndrome: a marker of karyotypic abnormalities associated with poor prognosis","volume":"82","author":"Sugimori","year":"2009","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb0975","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-03668-y","article-title":"Evaluation of the immature platelet fraction contribute to the differential diagnosis of hereditary, immune and other acquired thrombocytopenias","volume":"7","author":"Ferreira","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cca.2026.121171_bb0980","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1002\/ajh.23562","article-title":"Thrombopoietin levels in patients with disorders of platelet production: diagnostic potential and utility in predicting response to TPO receptor agonists","volume":"88","author":"Makar","year":"2013","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb0985","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/clinchem\/47.9.1660","article-title":"Is the thrombopoietin assay useful for differential diagnosis of thrombocytopenia? Analysis of a cohort of 160 patients with thrombocytopenia and defined platelet life span","volume":"47","author":"Gouin-Thibault","year":"2001","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cca.2026.121171_bb0990","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3109\/09537104.2010.494743","article-title":"Platelet distribution width and the extent of coronary artery disease: results from a large prospective study","volume":"21","author":"De Luca","year":"2010","journal-title":"Platelets"},{"key":"10.1016\/j.cca.2026.121171_bb0995","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/(SICI)1096-8652(199901)60:1<19::AID-AJH4>3.0.CO;2-1","article-title":"Use of the platelet histogram maximum in evaluating thrombocytopenia","volume":"60","author":"Niethammer","year":"1999","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb1000","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1111\/j.1365-2141.2004.05357.x","article-title":"Platelet size deviation width, platelet large cell ratio, and mean platelet volume have sufficient sensitivity and specificity in the diagnosis of immune thrombocytopenia","volume":"128","author":"Kaito","year":"2005","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb1005","doi-asserted-by":"crossref","DOI":"10.1097\/j.pbj.0000000000000094","article-title":"Diagnostic importance of mean platelet volume, platelet distribution width and platelet large cell ratio as screening tool in immune thrombocytopenia","volume":"5","author":"Khan","year":"2020","journal-title":"Porto Biomed. J."},{"key":"10.1016\/j.cca.2026.121171_bb1010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24054438","article-title":"Novel biomarkers for diagnosis and monitoring of immune thrombocytopenia","volume":"24","author":"Allegra","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cca.2026.121171_bb1015","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1055\/s-0039-1700512","article-title":"Immune thrombocytopenia in adults: modern approaches to diagnosis and treatment","volume":"46","author":"Al-Samkari","year":"2020","journal-title":"Semin. Thromb. Hemost."},{"key":"10.1016\/j.cca.2026.121171_bb1020","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1007\/s00277-022-04786-y","article-title":"Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives","volume":"101","author":"Vianelli","year":"2022","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb1025","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nrm.2017.125","article-title":"Shedding light on the cell biology of extracellular vesicles","volume":"19","author":"Van Niel","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cca.2026.121171_bb1030","doi-asserted-by":"crossref","DOI":"10.3390\/cells10112865","article-title":"Multiple myeloma cell-derived exosomes: implications on tumorigenesis, diagnosis, prognosis and therapeutic strategies","volume":"10","author":"Allegra","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.cca.2026.121171_bb1035","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1182\/blood-2008-06-163832","article-title":"Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles","volume":"113","author":"Flaumenhaft","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb1040","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/08880011003663390","article-title":"Platelet microparticles in immune thrombocytopenic purpura in pediatrics","volume":"27","author":"Tantawy","year":"2010","journal-title":"Pediatr. Hematol. Oncol."},{"key":"10.1016\/j.cca.2026.121171_bb1045","doi-asserted-by":"crossref","DOI":"10.1016\/j.thromres.2012.11.021","article-title":"Increased circulating red cell microparticles (RMP) and platelet microparticles (PMP) in immune thrombocytopenic purpura","volume":"131","author":"Sewify","year":"2013","journal-title":"Thromb. Res."},{"key":"10.1016\/j.cca.2026.121171_bb1050","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1111\/ijlh.14136","article-title":"Platelet genetic testing by next-generation sequencing: a practical update","volume":"45","author":"Chen","year":"2023","journal-title":"Int. J. Lab. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb1055","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/bjh.14471","article-title":"Dawning of the age of genomics for platelet granule disorders: improving insight, diagnosis and management","volume":"176","author":"Bariana","year":"2017","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb1060","doi-asserted-by":"crossref","DOI":"10.3390\/genes14030555","article-title":"Scoping Review on Epigenetic Mechanisms in Primary Immune Thrombocytopenia","volume":"14","author":"Tan","year":"2023","journal-title":"Genes (Basel)."},{"key":"10.1016\/j.cca.2026.121171_bb1065","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1111\/bjh.19987","article-title":"MicroRNA-199a-5p may be a diagnostic biomarker of primary ITP","volume":"206","author":"Garabet","year":"2025","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb1070","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1111\/bjh.20001","article-title":"The ITP diagnostic challenge","volume":"206","author":"Gonz\u00e1lez-L\u00f3pez","year":"2025","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb1075","first-page":"1","article-title":"Immune thrombocytopenia (ITP): current limitations in patient management","volume":"56","author":"Terrell","year":"2020","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.cca.2026.121171_bb1080","doi-asserted-by":"crossref","DOI":"10.1080\/14728214.2025.2590155","article-title":"Emerging therapeutic strategies in immune thrombocytopenia: an expert evaluation of the evolving treatment landscape","volume":"30","author":"Charbel","year":"2025","journal-title":"Expert Opin. Emerg. Drugs"},{"key":"10.1016\/j.cca.2026.121171_bb1085","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2025.101300","article-title":"The new era of primary immune thrombocytopenia management in adults: a narrative review of current and emerging treatments","volume":"73","author":"Gonz\u00e1lez-L\u00f3pez","year":"2025","journal-title":"Blood Rev."},{"key":"10.1016\/j.cca.2026.121171_bb1090","first-page":"e73","article-title":"Efficacy of dexamethasone for acute primary immune thrombocytopenia compared to prednisolone: a systematic review and Meta-analysis","volume":"1","author":"Arai","year":"2017","journal-title":"TH open companion J. To Thromb. Haemost."},{"key":"10.1016\/j.cca.2026.121171_bb1095","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1182\/bloodadvances.2019000966","article-title":"American Society of Hematology 2019 Guidelines for immune thrombocytopenia","volume":"3","author":"Neunert","year":"2019","journal-title":"Blood Adv."},{"key":"10.1016\/j.cca.2026.121171_bb1100","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.1182\/bloodadvances.2023012541","article-title":"The 2022 Review of the 2019 American Society of Hematology guidelines on immune thrombocytopenia","volume":"8","author":"Neunert","year":"2024","journal-title":"Blood Adv."},{"key":"10.1016\/j.cca.2026.121171_bb1105","doi-asserted-by":"crossref","first-page":"087","DOI":"10.1055\/s-0043-1769087","article-title":"Efficacy and safety analysis of combination therapy consisting of intravenous immunoglobulin and corticosteroids versus respective monotherapies in the treatment of relapsed ITP in adults","volume":"10","author":"Fang","year":"2023","journal-title":"Glob. Med. Genet."},{"key":"10.1016\/j.cca.2026.121171_bb1110","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3324\/haematol.10667","article-title":"The association between platelet autoantibody specificity and response to intravenous immunoglobulin G in the treatment of patients with immune thrombocytopenia","volume":"92","author":"Go","year":"2007","journal-title":"Haematologica"},{"key":"10.1016\/j.cca.2026.121171_bb1115","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.3324\/haematol.2018.212845","article-title":"Thrombopoietin receptor agonists: ten years later","volume":"104","author":"Ghanima","year":"2019","journal-title":"Haematologica"},{"key":"10.1016\/j.cca.2026.121171_bb1120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2040620719837906","article-title":"Switching thrombopoietin receptor agonist treatments in patients with primary immune thrombocytopenia","volume":"10","author":"Gonz\u00e1lez-Porras","year":"2019","journal-title":"Ther. Adv. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb1125","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2019.100647","article-title":"Tapering and discontinuation of thrombopoietin receptor agonists in immune thrombocytopenia: real-world recommendations","volume":"41","author":"Zaja","year":"2020","journal-title":"Blood Rev."},{"key":"10.1016\/j.cca.2026.121171_bb1130","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1111\/bjh.70069","article-title":"Real-world efficacy and safety of fostamatinib in ITP patients: Italian multicentre experience. GIMEMA ITP1122 study","volume":"207","author":"Lucchini","year":"2025","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.cca.2026.121171_bb1135","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/ajh.21501","article-title":"Short-term and long-term failure of laparoscopic splenectomy in adult immune thrombocytopenic purpura patients: a systematic review","volume":"84","author":"Mikhael","year":"2009","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.cca.2026.121171_bb1140","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1182\/blood-2012-09-455691","article-title":"Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia","volume":"121","author":"Gudbrandsdottir","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb1145","series-title":"Rituximab as Second-Line Treatment for Adult Immune Thrombocytopenia (the RITP Trial): A Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial, Lancet, London, England","first-page":"1653","volume":"vol. 385","author":"Ghanima","year":"2015"},{"key":"10.1016\/j.cca.2026.121171_bb1150","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1182\/blood.2019003599","article-title":"Identifying and treating refractory ITP: difficulty in diagnosis and role of combination treatment","volume":"135","author":"Miltiadous","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb1155","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1182\/blood.2024027336","article-title":"Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study","volume":"145","author":"Kuter","year":"2025","journal-title":"Blood"},{"key":"10.1016\/j.cca.2026.121171_bb1160","doi-asserted-by":"crossref","DOI":"10.1016\/j.coi.2026.102775","article-title":"Hot topics in the antiphospholipid syndrome","volume":"100","author":"Fujieda","year":"2026","journal-title":"Curr. Opin. Immunol."}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898126003530?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898126003530?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:49:01Z","timestamp":1788900541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898126003530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":232,"alternative-id":["S0009898126003530"],"URL":"https:\/\/doi.org\/10.1016\/j.cca.2026.121171","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In-vitro diagnostics of adult immune thrombocytopenia - status quo and new developments","name":"articletitle","label":"Article Title"},{"value":"Clinica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cca.2026.121171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"121171"}}