{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:28:03Z","timestamp":1787502483441,"version":"build-2736575974"},"reference-count":41,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","criticalcare.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Critical Care Clinics"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.ccc.2017.06.005","type":"journal-article","created":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T13:00:56Z","timestamp":1501333256000},"page":"825-841","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"title":["Pediatric Extracorporeal Membrane Oxygenation"],"prefix":"10.1016","volume":"33","author":[{"given":"Christopher Loren","family":"Jenks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi","family":"Raman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi J.","family":"Dalton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ccc.2017.06.005_bib1","series-title":"ECMO specialist training manual","first-page":"1","author":"Short","year":"2010"},{"issue":"4","key":"10.1016\/j.ccc.2017.06.005_bib2","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1542\/peds.76.4.479","article-title":"Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study","volume":"76","author":"Bartlett","year":"1985","journal-title":"Pediatrics"},{"key":"10.1016\/j.ccc.2017.06.005_bib3","series-title":"Pediatric critical care","author":"Fuhrman","year":"2017"},{"key":"10.1016\/j.ccc.2017.06.005_bib4","series-title":"ECMO: extracorporeal cardiopulmonary support in critical care","author":"Annich","year":"2012"},{"issue":"2","key":"10.1016\/j.ccc.2017.06.005_bib5","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/MAT.0000000000000173","article-title":"Circuit oxygenator contributes to extracorporeal membrane oxygenation-induced hemolysis","volume":"61","author":"Williams","year":"2015","journal-title":"ASAIO J"},{"issue":"3","key":"10.1016\/j.ccc.2017.06.005_bib6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/01.PCC.0000075321.45152.B8","article-title":"Venovenous extracorporeal membrane oxygenation: an underutilized technique?","volume":"4","author":"Dalton","year":"2003","journal-title":"Pediatr Crit Care Med"},{"issue":"4","key":"10.1016\/j.ccc.2017.06.005_bib7","first-page":"724","article-title":"Hypertension during extracorporeal membrane oxygenation: cause, effect, and management","volume":"102","author":"Sell","year":"1987","journal-title":"Surgery"},{"issue":"7","key":"10.1016\/j.ccc.2017.06.005_bib8","first-page":"E166","article-title":"Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology","volume":"7","author":"Makdisi","year":"2015","journal-title":"J\u00a0Thorac Dis"},{"issue":"5","key":"10.1016\/j.ccc.2017.06.005_bib9","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/CCM.0000000000000128","article-title":"Hemolysis in pediatric patients receiving centrifugal-pump extracorporeal membrane oxygenation: prevalence, risk factors, and outcomes","volume":"42","author":"Lou","year":"2014","journal-title":"Crit Care Med"},{"issue":"2","key":"10.1016\/j.ccc.2017.06.005_bib10","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/CCM.0b013e3181fb7b35","article-title":"Extracorporeal membrane oxygenation for pediatric respiratory failure: survival and predictors of mortality","volume":"39","author":"Zabrocki","year":"2011","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/PCC.0b013e3182604896","article-title":"Critical appraisal of Zabrocki et\u00a0al: extracorporeal membrane oxygenation for pediatric respiratory failure: survival and predictors of mortality. Crit Care Med 2011; 39:364-370","volume":"14","author":"Musick","year":"2013","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.ccc.2017.06.005_bib12","doi-asserted-by":"crossref","unstructured":"ELSO: Extracorporeal life support organization, Version 1.3. 2013.","DOI":"10.1007\/978-88-470-5427-1_1"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/CCM.0000000000001383","article-title":"Open lung approach for the acute respiratory distress syndrome: a pilot, randomized controlled trial","volume":"44","author":"Kacmarek","year":"2016","journal-title":"Crit Care Med"},{"issue":"12","key":"10.1016\/j.ccc.2017.06.005_bib14","first-page":"1304","article-title":"Open lung in ARDS","volume":"24","author":"Haitsma","year":"2003","journal-title":"Acta Pharmacol Sin"},{"issue":"4","key":"10.1016\/j.ccc.2017.06.005_bib15","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000069482","article-title":"Application of the open-lung concept during positive-pressure ventilation reduces pulmonary inflammation in newborn piglets","volume":"83","author":"van Kaam","year":"2003","journal-title":"Biol Neonate"},{"issue":"11","key":"10.1016\/j.ccc.2017.06.005_bib16","first-page":"1170","article-title":"International survey on the management of mechanical ventilation during ECMO in adults with severe respiratory failure","volume":"81","author":"Camporota","year":"2015","journal-title":"Minerva Anestesiol"},{"issue":"2","key":"10.1016\/j.ccc.2017.06.005_bib17","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/TA.0000000000000518","article-title":"Lung protective ventilation (ARDSNet) versus airway pressure release ventilation: ventilatory management in a combined model of acute lung and brain injury","volume":"78","author":"Davies","year":"2015","journal-title":"J\u00a0Trauma Acute Care Surg"},{"issue":"9","key":"10.1016\/j.ccc.2017.06.005_bib18","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1097\/PCC.0000000000000235","article-title":"Extubation during pediatric extracorporeal membrane oxygenation: a single-center experience","volume":"15","author":"Anton-Martin","year":"2014","journal-title":"Pediatr Crit Care Med"},{"issue":"6","key":"10.1016\/j.ccc.2017.06.005_bib19","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1513\/AnnalsATS.201403-100BC","article-title":"Mechanical ventilation during extracorporeal membrane oxygenation. An international survey","volume":"11","author":"Marhong","year":"2014","journal-title":"Ann Am Thorac Soc"},{"issue":"5","key":"10.1016\/j.ccc.2017.06.005_bib20","first-page":"312","article-title":"A\u00a0systematic review on pharmacokinetic changes in critically ill patients: role of extracorporeal membrane oxygenation","volume":"19","author":"Mousavi","year":"2011","journal-title":"Daru"},{"issue":"3","key":"10.1016\/j.ccc.2017.06.005_bib21","doi-asserted-by":"crossref","first-page":"218","DOI":"10.4103\/0971-9784.84030","article-title":"Extracorporeal membrane oxygenation, an anesthesiologist's perspective: physiology and principles. Part 1","volume":"14","author":"Chauhan","year":"2011","journal-title":"Ann Card Anaesth"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib22","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/0267659112456894","article-title":"In\u00a0vitro clearance of dexmedetomidine in extracorporeal membrane oxygenation","volume":"28","author":"Wagner","year":"2013","journal-title":"Perfusion"},{"issue":"5","key":"10.1016\/j.ccc.2017.06.005_bib23","first-page":"407","article-title":"Three-year experience of using venovenous extracorporeal membrane oxygenation for patients with severe respiratory failure","volume":"20","author":"Ng","year":"2014","journal-title":"Hong Kong Med J"},{"issue":"2","key":"10.1016\/j.ccc.2017.06.005_bib24","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/MAT.0000000000000461","article-title":"Safety of propofol for oxygenator exchange in extracorporeal membrane oxygenation","volume":"63","author":"Hohlfelder","year":"2017","journal-title":"ASAIO J"},{"issue":"12","key":"10.1016\/j.ccc.2017.06.005_bib25","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1097\/PCC.0000000000000955","article-title":"Antithrombin concentrate use in pediatric extracorporeal membrane oxygenation: a multicenter cohort study","volume":"17","author":"Wong","year":"2016","journal-title":"Pediatr Crit Care Med"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/MAT.0000000000000010","article-title":"Antithrombin III supplementation on extracorporeal membrane oxygenation: impact on heparin dose and circuit life","volume":"60","author":"Byrnes","year":"2014","journal-title":"ASAIO J"},{"issue":"5","key":"10.1016\/j.ccc.2017.06.005_bib27","first-page":"513","article-title":"Use of a novel anticoagulation strategy during ECMO in a pediatric population: single-center experience","volume":"52","author":"Agati","year":"2006","journal-title":"ASAIO J"},{"issue":"12","key":"10.1016\/j.ccc.2017.06.005_bib28","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1097\/PCC.0000000000000970","article-title":"The incidence of acute kidney injury and its effect on neonatal and pediatric extracorporeal membrane oxygenation outcomes: a Multicenter Report from the Kidney Intervention during Extracorporeal Membrane Oxygenation Study Group","volume":"17","author":"Fleming","year":"2016","journal-title":"Pediatr Crit Care Med"},{"issue":"4","key":"10.1016\/j.ccc.2017.06.005_bib29","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/PCC.0000000000000659","article-title":"Fluid overload is associated with higher mortality and morbidity in pediatric patients undergoing cardiac surgery","volume":"17","author":"Lex","year":"2016","journal-title":"Pediatr Crit Care Med"},{"issue":"6","key":"10.1016\/j.ccc.2017.06.005_bib30","first-page":"378","article-title":"Enhanced hemolysis in pediatric patients requiring extracorporeal membrane oxygenation and continuous renal replacement therapy","volume":"13","author":"Betrus","year":"2007","journal-title":"Ann Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib31","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/0267659110396015","article-title":"Hemolysis and ECMO pumps in the 21st century","volume":"26","author":"Toomasian","year":"2011","journal-title":"Perfusion"},{"issue":"4","key":"10.1016\/j.ccc.2017.06.005_bib32","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1681\/ASN.V104846","article-title":"Cytokine removal during continuous hemofiltration in septic patients","volume":"10","author":"De Vriese","year":"1999","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.ccc.2017.06.005_bib33","doi-asserted-by":"crossref","DOI":"10.1177\/0148607116673185","article-title":"Underweight status is an independent predictor of in-hospital mortality in pediatric patients on extracorporeal membrane oxygenation","author":"Anton-Martin","year":"2016","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"11","key":"10.1016\/j.ccc.2017.06.005_bib34","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1007\/s00134-013-3053-2","article-title":"Nutrition support during extracorporeal membrane oxygenation (ECMO) in adults: a retrospective audit of 86 patients","volume":"39","author":"Ferrie","year":"2013","journal-title":"Intensive Care Med"},{"issue":"3","key":"10.1016\/j.ccc.2017.06.005_bib35","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1177\/0148607110369225","article-title":"Clinical guidelines: nutrition support of neonates supported with extracorporeal membrane oxygenation","volume":"34","author":"Jaksic","year":"2010","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"12 Suppl 1","key":"10.1016\/j.ccc.2017.06.005_bib36","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/01.ccm.0000474228.17116.32","article-title":"400: risk factors for hemolysis on ECMO: a comparison between centrifugal and roller pumps","volume":"43","author":"Jenks","year":"2015","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.ccc.2017.06.005_bib37","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1097\/MAT.0b013e31819099f8","article-title":"Plasma exchange during cardiopulmonary bypass in patients with severe hemolysis in cardiac surgery","volume":"55","author":"Hei","year":"2009","journal-title":"ASAIO J"},{"issue":"2","key":"10.1016\/j.ccc.2017.06.005_bib38","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/0267659112464096","article-title":"Successful management of bleeding complications in patients supported with extracorporeal membrane oxygenation with primary respiratory failure","volume":"28","author":"Lamb","year":"2013","journal-title":"Perfusion"},{"key":"10.1016\/j.ccc.2017.06.005_bib39","article-title":"Regional cerebral abnormalities measured by frequency-domain near-infrared spectroscopy in pediatric patients during extracorporeal membrane oxygenation","author":"Tian","year":"2016","journal-title":"ASAIO J"},{"issue":"5","key":"10.1016\/j.ccc.2017.06.005_bib40","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/ejcts\/ezs524","article-title":"Diagnosis of infection in paediatric veno-arterial cardiac extracorporeal membrane oxygenation: role of procalcitonin and C-reactive protein","volume":"43","author":"Rungatscher","year":"2013","journal-title":"Eur J Cardiothorac Surg"},{"issue":"10","key":"10.1016\/j.ccc.2017.06.005_bib41","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1097\/CCM.0000000000001145","article-title":"Plasma biomarkers of brain injury as diagnostic tools and outcome predictors after extracorporeal membrane oxygenation","volume":"43","author":"Bembea","year":"2015","journal-title":"Crit Care Med"}],"container-title":["Critical Care Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749070417300477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749070417300477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T12:21:23Z","timestamp":1659270083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749070417300477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0749070417300477"],"URL":"https:\/\/doi.org\/10.1016\/j.ccc.2017.06.005","relation":{},"ISSN":["0749-0704"],"issn-type":[{"value":"0749-0704","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pediatric Extracorporeal Membrane Oxygenation","name":"articletitle","label":"Article Title"},{"value":"Critical Care Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccc.2017.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}