{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:05:21Z","timestamp":1789653921335,"version":"4.0.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1016\/j.cccn.2004.03.007","type":"journal-article","created":{"date-parts":[[2004,5,8]],"date-time":"2004-05-08T10:30:56Z","timestamp":1084012256000},"page":"89-92","source":"Crossref","is-referenced-by-count":14,"title":["Analysis of cysteinyl leukotrienes and their metabolites in bile of patients with peroxisomal or mitochondrial \u03b2-oxidation defects"],"prefix":"10.1016","volume":"345","author":[{"given":"Ertan","family":"Mayatepek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Ferdinandusse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Meissner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.A.","family":"Wanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cccn.2004.03.007_BIB1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1203\/00006450-199501000-00001","article-title":"Leukotrienes: biosynthesis, metabolism and pathophysiologic significance","volume":"37","author":"Mayatepek","year":"1995","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.cccn.2004.03.007_BIB2","doi-asserted-by":"crossref","first-page":"21771","DOI":"10.1016\/S0021-9258(18)45807-3","article-title":"Leukotrierne E4 elimination and metabolism in normal human subjects","volume":"265","author":"Sala","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cccn.2004.03.007_BIB3","doi-asserted-by":"crossref","first-page":"24763","DOI":"10.1016\/S0021-9258(18)54295-2","article-title":"Peroxisomal degradation of leukotrienes by \u03b2-oxidation from the \u03c9-end","volume":"266","author":"Jedlitschky","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cccn.2004.03.007_BIB4","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1172\/JCI116309","article-title":"Impaired degradation of leukotrienes in patients with peroxisome deficiency disorders","volume":"91","author":"Mayatepek","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cccn.2004.03.007_BIB5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0009-8981(93)90182-4","article-title":"Increased excretion of endogenous urinary leukotriene E4 in extrahepatic cholestasis","volume":"218","author":"Mayatepek","year":"1993","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.cccn.2004.03.007_BIB6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0065-2571(92)90011-N","article-title":"Transport and in vivo elimination of cysteinyl leukotrienes","volume":"32","author":"Keppler","year":"1992","journal-title":"Adv. Enzyme Regul."},{"key":"10.1016\/j.cccn.2004.03.007_BIB7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0091-6749(90)90214-O","article-title":"Leukotriene C4 elimination and metabolism in man","volume":"85","author":"Maltby","year":"1990","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.cccn.2004.03.007_BIB8","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0022-3476(05)81548-3","article-title":"Enhanced urinary excretion of leukotriene E4 in patients with mevalonate kinase deficiency","volume":"123","author":"Mayatepek","year":"1993","journal-title":"J. Pediatr."},{"key":"10.1016\/j.cccn.2004.03.007_BIB9","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1034\/j.1398-9995.2001.00973.x","article-title":"Urinary leukotriene E4, eosinophil protein X, and nasal eosinophil cationic protein are not associated with respiratory symptoms in 1-year-old children","volume":"56","author":"Wojnarowski","year":"2001","journal-title":"Allergy"},{"key":"10.1016\/j.cccn.2004.03.007_BIB10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/adc.85.2.158","article-title":"Increased urinary leukotriene E4 during febrile attacks in the hyperimmunoglobulinaemia D and periodic fever syndrome","volume":"85","author":"Frenkel","year":"2001","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.cccn.2004.03.007_BIB11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0378-4347(95)00027-G","article-title":"Chemical synthesis of dioxygen-18labelled \u03c9-\/\u03b2-oxidized cysteinyl leukotrienes: analysis by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry","volume":"667","author":"Tsikas","year":"1995","journal-title":"J. Chromatogr. B, Biomed. Appl."},{"key":"10.1016\/j.cccn.2004.03.007_BIB12","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/hep.1840050530","article-title":"The relation of leukotrienes to liver injury","volume":"5","author":"Keppler","year":"1985","journal-title":"Hepatology"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898104001226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898104001226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T11:22:35Z","timestamp":1623928955000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898104001226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":12,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["S0009898104001226"],"URL":"https:\/\/doi.org\/10.1016\/j.cccn.2004.03.007","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}