{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:31:16Z","timestamp":1760315476831,"version":"build-2065373602"},"reference-count":48,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Critical Care Nursing Clinics of North America"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.ccell.2011.08.007","type":"journal-article","created":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T12:28:37Z","timestamp":1322051317000},"page":"617-634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pulmonary Issues in Acute and Critical Care: Pulmonary Embolism and Ventilator-induced Lung Injury"],"prefix":"10.1016","volume":"23","author":[{"given":"Sonya","family":"Flanders","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Gunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2006","series-title":"The Merck manual of diagnosis and therapy","key":"10.1016\/j.ccell.2011.08.007_bib1"},{"key":"10.1016\/j.ccell.2011.08.007_bib2","series-title":"Pathophysiology: the biologic basis for disease in adults and children","article-title":"Alterations of pulmonary function","author":"Brashers","year":"2006"},{"key":"10.1016\/j.ccell.2011.08.007_bib3","doi-asserted-by":"crossref","first-page":"I4","DOI":"10.1161\/01.CIR.0000078468.11849.66","article-title":"The epidemiology of venous thromboembolism","volume":"107","author":"White","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ccell.2011.08.007_bib4","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1161\/ATVBAHA.108.162545","article-title":"The epidemiology of venous thromboembolism in the community","volume":"28","author":"Heit","year":"2008","journal-title":"Arterioscler Thromb Vac Biol"},{"key":"10.1016\/j.ccell.2011.08.007_bib5","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1160\/TH03-03-0152","article-title":"Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures","volume":"90","author":"White","year":"2003","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.ccell.2011.08.007_bib6","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.ccm.2010.06.007","article-title":"Mortality risk assessment and the role of thrombolysis in pulmonary embolism","volume":"31","author":"Lankeit","year":"2010","journal-title":"Clin Chest Med"},{"year":"2009","series-title":"Venouos thromboembolism","key":"10.1016\/j.ccell.2011.08.007_bib7"},{"key":"10.1016\/j.ccell.2011.08.007_bib8","doi-asserted-by":"crossref","first-page":"I9","DOI":"10.1161\/01.CIR.0000078469.07362.E6","article-title":"Risk factors for venous thromboembolism","volume":"107","author":"Anderson","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ccell.2011.08.007_bib9","series-title":"AACN advanced critical care","first-page":"347","article-title":"Vascular emergencies","author":"Dirks","year":"2009"},{"key":"10.1016\/j.ccell.2011.08.007_bib10","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.amjmed.2008.05.045","article-title":"Epidemiology of venous thromboembolism in cardiorespiratory and infectious disease","volume":"121","author":"Alikhan","year":"2008","journal-title":"Am J Med"},{"key":"10.1016\/j.ccell.2011.08.007_bib11","doi-asserted-by":"crossref","first-page":"381S","DOI":"10.1378\/chest.08-0656","article-title":"Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"133","author":"Geerts","year":"2008","journal-title":"Chest"},{"year":"2011","series-title":"Fondaparinux","author":"Deglin","key":"10.1016\/j.ccell.2011.08.007_bib12"},{"key":"10.1016\/j.ccell.2011.08.007_bib13","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1001\/archinte.167.14.1476","article-title":"Pharmacological venous thromboembolism prophylaxis in hospitalized medical patients: a meta-analysis of randomized controlled trials","volume":"167","author":"Wein","year":"2007","journal-title":"Arch Intern Med"},{"year":"2011","series-title":"Dalteparin","author":"Deglin","key":"10.1016\/j.ccell.2011.08.007_bib14"},{"year":"2011","series-title":"Enoxaparin","author":"Deglin","key":"10.1016\/j.ccell.2011.08.007_bib15"},{"key":"10.1016\/j.ccell.2011.08.007_bib16","doi-asserted-by":"crossref","first-page":"454S","DOI":"10.1378\/chest.08-0658","article-title":"Antithrombotic therapy for venous thromboembolic disease","volume":"133","author":"Kearon","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.ccell.2011.08.007_bib17","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1378\/chest.09-0608","article-title":"Troponin-based risk stratification of patients with acute nonmassive pulmonary embolism: systematic review and metaanalysis","volume":"136","author":"Jim\u00e9nez","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.ccell.2011.08.007_bib18","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra0907731","article-title":"Acute pulmonary embolism","volume":"363","author":"Agnelli","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ccell.2011.08.007_bib19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/00002727-200501000-00007","article-title":"Prevention and treatment of deep vein thrombosis and pulmonary embolism in critically ill patients","volume":"28","author":"Yang","year":"2005","journal-title":"Crit Care Nurs Q"},{"year":"2011","series-title":"Tinzaparin","author":"Deglin","key":"10.1016\/j.ccell.2011.08.007_bib20"},{"key":"10.1016\/j.ccell.2011.08.007_bib21","doi-asserted-by":"crossref","first-page":"27S","DOI":"10.3928\/01477447-20100722-64","article-title":"New oral antithrombotic agents for the prevention of deep venous thrombosis and pulmonary embolism in orthopedic surgery","volume":"33","author":"Merli","year":"2010","journal-title":"Orthopedics"},{"key":"10.1016\/j.ccell.2011.08.007_bib22","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1378\/chest.08-2125","article-title":"Thrombolytic therapy for acute pulmonary embolism","volume":"135","author":"Todd","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.ccell.2011.08.007_bib23","doi-asserted-by":"crossref","first-page":"785","DOI":"10.4065\/mcp.2010.0250","article-title":"A more aggressive approach to emergency embolectomy for acute pulmonary embolism","volume":"85","author":"Sareyyupoglu","year":"2010","journal-title":"Mayo Clin Proc"},{"year":"2011","series-title":"Accreditation manual: hospital","key":"10.1016\/j.ccell.2011.08.007_bib24"},{"year":"2010","series-title":"Specifications manual for national hospital inpatient quality measures","key":"10.1016\/j.ccell.2011.08.007_bib25"},{"key":"10.1016\/j.ccell.2011.08.007_bib26","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4037\/ajcc2009724","article-title":"Not-so-trivial pursuit: mechanical ventilation risk reduction","volume":"18","author":"Grap","year":"2009","journal-title":"Am J Crit Care"},{"key":"10.1016\/j.ccell.2011.08.007_bib27","series-title":"AACN protocols for practice: care of mechanically ventilated patients","first-page":"59","article-title":"Invasive and noninvasive modes and methods of mechanical ventilation","author":"Pierce","year":"2007"},{"key":"10.1016\/j.ccell.2011.08.007_bib28","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.suc.2006.08.005","article-title":"Basic ventilator management: lung protective strategies","volume":"86","author":"Donahoe","year":"2006","journal-title":"Surg Clin North Am"},{"key":"10.1016\/j.ccell.2011.08.007_bib29","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1097\/01.CCM.0000133019.52531.30","article-title":"Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation","volume":"32","author":"Gajic","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccell.2011.08.007_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1136\/thx.2008.102228","article-title":"Intraoperative ventilator settings and acute lung injury after elective surgery: a nested case control study","volume":"64","author":"Fern\u00e1ndez-P\u00e9rez","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.ccell.2011.08.007_bib31","doi-asserted-by":"crossref","first-page":"915","DOI":"10.12968\/bjon.2009.18.15.43560","article-title":"Principles of mechanical ventilation\u2014a critical review","volume":"18","author":"Pertab","year":"2009","journal-title":"Br J Nurs"},{"key":"10.1016\/j.ccell.2011.08.007_bib32","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/00002727-200407000-00006","article-title":"Mechanical ventilation: what have we learned?","volume":"27","author":"Fenstermacher","year":"2004","journal-title":"Crit Care Nurs Q"},{"key":"10.1016\/j.ccell.2011.08.007_bib33","first-page":"55","article-title":"Caring for the mechanically ventilated patient: part one","volume":"20","author":"Newmarch","year":"2006","journal-title":"Nurs Stand"},{"key":"10.1016\/j.ccell.2011.08.007_bib34","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0140-6736(03)12329-X","article-title":"Ventilator-associated lung injury","volume":"361","author":"Pinhu","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ccell.2011.08.007_bib35","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1097\/01.anes.0000267607.25011.e8","article-title":"What tidal volumes should be used in patients without acute lung injury?","volume":"106","author":"Schultz","year":"2007","journal-title":"Anesthesiology"},{"year":"2000","series-title":"ARMA Study","key":"10.1016\/j.ccell.2011.08.007_bib36"},{"key":"10.1016\/j.ccell.2011.08.007_bib37","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1097\/ALN.0b013e3181b76545","article-title":"Ventilator-induced lung injury: less ventilation, less injury","volume":"111","author":"Bigatello","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ccell.2011.08.007_bib38","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1093\/bjaceaccp\/mkp028","article-title":"Acute lung injury and acute respiratory distress syndrome","volume":"9","author":"Mackay","year":"2009","journal-title":"Continuing Education in Anaesthesia, Critical Care & Pain"},{"key":"10.1016\/j.ccell.2011.08.007_bib39","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.iccn.2004.07.004","article-title":"Methods to prevent ventilator-associated lung injury: a summary","volume":"20","author":"Cooper","year":"2004","journal-title":"Int Crit Care Nurs"},{"year":"2011","series-title":"Barotrauma, pulmonary: mechanical ventilation","author":"Schub","key":"10.1016\/j.ccell.2011.08.007_bib40"},{"key":"10.1016\/j.ccell.2011.08.007_bib41","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1378\/chest.113.6.1698","article-title":"Radiographic assessment of hyperinflation: correlation with objective chest radiographic measurements and mechanical ventilator parameters","volume":"113","author":"Johnson","year":"1998","journal-title":"Chest"},{"year":"2011","series-title":"Atelectasis: mechanical ventilation","author":"Lewis","key":"10.1016\/j.ccell.2011.08.007_bib42"},{"key":"10.1016\/j.ccell.2011.08.007_bib43","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.aucc.2009.06.004","article-title":"Lung recruitment\u2014a guide for clinicians","volume":"22","author":"Jauncey-Cooke","year":"2009","journal-title":"Aust Crit Care"},{"key":"10.1016\/j.ccell.2011.08.007_bib44","first-page":"33","article-title":"Lung recruitment: a role in mechanical ventilation","volume":"46","author":"Papadakos","year":"2010","journal-title":"Canadian Journal of Respiratory Therapy"},{"key":"10.1016\/j.ccell.2011.08.007_bib45","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/01.anes.0000358753.29528.fb","article-title":"Mechanical ventilation: taking its toll on the lung","volume":"111","author":"Curley","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ccell.2011.08.007_bib46","doi-asserted-by":"crossref","first-page":"R182","DOI":"10.1186\/cc8168","article-title":"Ventilator-induced endothelial activation and inflammation in the lung and distal organs","volume":"13","author":"Hegeman","year":"2009","journal-title":"Crit Care"},{"key":"10.1016\/j.ccell.2011.08.007_bib47","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1478-5153.2007.00224.x","article-title":"Using pressure-volume curves to set proper PEEP in acute lung injury","volume":"12","author":"LaFollette","year":"2007","journal-title":"Nurs Crit Care"},{"key":"10.1016\/j.ccell.2011.08.007_bib48","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.trsl.2010.01.006","article-title":"From a distance: ventilation-dependent extra-pulmonary injury","volume":"155","author":"Kuebler","year":"2010","journal-title":"Transl Res"}],"container-title":["Critical Care Nursing Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899588511000359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899588511000359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:26:06Z","timestamp":1760268366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899588511000359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0899588511000359"],"URL":"https:\/\/doi.org\/10.1016\/j.ccell.2011.08.007","relation":{},"ISSN":["0899-5885"],"issn-type":[{"type":"print","value":"0899-5885"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pulmonary Issues in Acute and Critical Care: Pulmonary Embolism and Ventilator-induced Lung Injury","name":"articletitle","label":"Article Title"},{"value":"Critical Care Nursing Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccell.2011.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}