{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:30:46Z","timestamp":1760315446958,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Critical Care Nursing Clinics of North America"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.ccell.2013.02.013","type":"journal-article","created":{"date-parts":[[2013,4,6]],"date-time":"2013-04-06T05:31:11Z","timestamp":1365226271000},"page":"165-172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tick Bites and Lyme Disease"],"prefix":"10.1016","volume":"25","author":[{"given":"Maria L.","family":"Overstreet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ccell.2013.02.013_bib1","unstructured":"Centers for Disease Control and Prevention. Statistics on Lyme disease. Available at: http:\/\/www.cdc.gov\/lyme\/stats\/index.html. Accessed February 16, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib2","unstructured":"Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report. Available at: http:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm5953a1html. Accessed February 21, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib3","unstructured":"Sigal LH. Epidemiology and clinical manifestations of Lyme disease. Up to date. Available at: http:\/\/www.uptodateonline.com\/application\/topic\/print.asp?file=othr_inf\/6836&;type=A&s. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib4","unstructured":"Centers for Disease Control and Prevention. Lifecycle of blacklegged ticks. Available at: http:\/\/www.cdc.gov\/lyme\/transmission\/blacklegged.html\/. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib5","unstructured":"Sigal LH. Bacteriology and epidemiology of Lyme disease. Up to date. Available at: http:\/\/www.uptodateonline.com\/utd\/content\/topic.do?topicKey=tickflea\/7074&;view=print. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib6","unstructured":"Centers for Disease Control and Prevention. Life cycle of hard ticks that spread disease. Available at: http:\/\/www.cdc.gov\/ticks\/life_cycle_and_hosts.html. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib7","unstructured":"Massachusetts Department of Public Health, Division of Epidemiology and Immunization. Tickborne diseases in Massachusetts: a physician\u2019s reference manual. 2nd edition. Available at: http:\/\/www.mass.gov\/eohhs\/docs\/dph\/cdc\/lyme\/tickborne-diseases-physician-manual.pdf. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib8","unstructured":"Centers for Disease Control and Prevention. Reported clinical findings among Lyme disease patients. Available at: http:\/\/www.cdc.gov\/ncidod\/dvbid\/lyme\/ld_bysymptoms.htm. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib9","unstructured":"Centers for Disease Control and Prevention. Signs and symptoms of Lyme disease. Available at: http:\/\/www.cdc.gov\/lyme\/signs_symptoms\/index.html. Accessed February 16, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib10","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.idc.2007.12.011","article-title":"Chronic lyme disease: a review","volume":"22","author":"Marques","year":"2008","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.ccell.2013.02.013_bib11","unstructured":"Hu L. Immunopathogenesis of Lyme Disease. Up to date. Available at: http:\/\/www.uptodate.com.proxy.library.vanderbilt.edu\/contents\/immunopathogenesis-of-lyme-disease?source=search_result&search=Lyme+disease&selectedTitle=10%7E150. Accessed March 23, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib12","unstructured":"National Institute of Allergy and Infectious Diseases. National Institutes of Health. NIAID Research. Co-infection. Available at: http:\/\/www.nih.gov\/research\/topics\/lyme\/research\/co-infection\/. Accessed February 20, 2013."},{"issue":"Suppl 1","key":"10.1016\/j.ccell.2013.02.013_bib13","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1086\/314053","article-title":"Practice guidelines for the treatment of Lyme disease","volume":"31","author":"Wormser","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ccell.2013.02.013_bib14","doi-asserted-by":"crossref","first-page":"212149","DOI":"10.1001\/archinte.158.19.2149","article-title":"Human babesiosis in New York State: review of 139 hospitalized cases and analysis of prognostic factors","volume":"158","author":"White","year":"1998","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ccell.2013.02.013_bib15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1001\/jama.1996.03530270039029","article-title":"Clinical and laboratory characteristics of human granulocytic ehrlichiosis","volume":"275","author":"Bakken","year":"1996","journal-title":"JAMA"},{"year":"2003","series-title":"Evaluation of antibiotic treatment in patients with persistent symptoms of Lyme disease: an ILADS position paper","author":"Bransfield","key":"10.1016\/j.ccell.2013.02.013_bib16"},{"key":"10.1016\/j.ccell.2013.02.013_bib17","unstructured":"Centers for Disease Control and Prevention. Lyme disease diagnosis. Available at: http:\/\/www.cdc.gov\/ncidod\/dvbid\/lyme\/ld_humandisease_diagnosis.htm. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib18","unstructured":"Centers for Disease Control and Prevention. Other types of laboratory testing. Available at: http:\/\/www.cdc.gov\/lyme\/diagnosistesting\/LabTest\/OtherLab\/index.html. Accessed February 20, 2013."},{"key":"10.1016\/j.ccell.2013.02.013_bib19","unstructured":"Centers for Disease Control and Prevention. Tick removal. Available at: http:\/\/www.cdc.gov\/lyme\/removal\/index.html. Accessed February 20, 2013."},{"year":"2006","series-title":"The Sanford guide to antimicrobial therapy","author":"Gilbert","key":"10.1016\/j.ccell.2013.02.013_bib20"},{"key":"10.1016\/j.ccell.2013.02.013_bib21","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1093\/cid\/cis402","article-title":"Treatment of erythema migrans with doxycycline for 10 days versus 15 days","volume":"55","author":"Stupica","year":"2012","journal-title":"Clin Infect Dis"}],"container-title":["Critical Care Nursing Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089958851300021X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089958851300021X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:26:54Z","timestamp":1760268414000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089958851300021X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S089958851300021X"],"URL":"https:\/\/doi.org\/10.1016\/j.ccell.2013.02.013","relation":{},"ISSN":["0899-5885"],"issn-type":[{"type":"print","value":"0899-5885"}],"subject":[],"published":{"date-parts":[[2013,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tick Bites and Lyme Disease","name":"articletitle","label":"Article Title"},{"value":"Critical Care Nursing Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccell.2013.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}