{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:12:58Z","timestamp":1790809978978,"version":"4.1.0"},"reference-count":86,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Cell"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.ccell.2026.07.001","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:36:27Z","timestamp":1785162987000},"page":"1815-1831.e11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies"],"prefix":"10.1016","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1253-2250","authenticated-orcid":false,"given":"R. Ryan","family":"Meyerhoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen M.","family":"Anadon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Uriel","family":"Lopez Bailon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayan","family":"Carrion-Estrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koravit","family":"Poysungnoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Lindenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabor","family":"Kemeny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Lyniv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaibjav","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2592-0391","authenticated-orcid":false,"given":"Ricardo","family":"Chaurio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noah","family":"Plappert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Evangelous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Soo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eziafa","family":"Oduah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Glass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent","family":"Weinhold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Gregory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W.","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0089-277X","authenticated-orcid":false,"given":"Priyamvada","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal","family":"Ready","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6431-4074","authenticated-orcid":false,"given":"Jose R.","family":"Conejo-Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilton B.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott J.","family":"Antonia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ccell.2026.07.001_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.954936","article-title":"Role of B cells as antigen presenting cells","volume":"13","author":"Rastogi","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib2","doi-asserted-by":"crossref","first-page":"4790","DOI":"10.1016\/j.cell.2024.06.038","article-title":"Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes","volume":"187","author":"Yang","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/cei\/uxac090","article-title":"Cytokine production by human B cells: role in health and autoimmune disease","volume":"210","author":"de Gruijter","year":"2022","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib4","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/j.ccell.2024.09.011","article-title":"A pan-cancer single-cell RNA-seq atlas of intratumoral B cells","volume":"42","author":"Fitzsimons","year":"2024","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib5","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.cell.2022.02.012","article-title":"Tumor-reactive antibodies evolve from non-binding and autoreactive precursors","volume":"185","author":"Mazor","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib6","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2021.1900635","article-title":"Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer","volume":"10","author":"Gunderson","year":"2021","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.ccell.2026.07.001_bib7","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1038\/s41568-022-00466-1","article-title":"Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities","volume":"22","author":"Laumont","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.canlet.2013.01.036","article-title":"The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer","volume":"333","author":"Lohr","year":"2013","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ccell.2026.07.001_bib9","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/s41586-019-1906-8","article-title":"B cells are associated with survival and immunotherapy response in sarcoma","volume":"577","author":"Petitprez","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ccell.2026.07.001_bib10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.ccell.2022.02.002","article-title":"Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer","volume":"40","author":"Patil","year":"2022","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib11","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.ccell.2023.02.017","article-title":"B cells in the tumor microenvironment: Multi-faceted organizers, regulators, and effectors of anti-tumor immunity","volume":"41","author":"Laumont","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib12","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.1038\/s41467-021-23355-x","article-title":"B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma","volume":"12","author":"Ruffin","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ccell.2026.07.001_bib13","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1038\/s41590-020-0769-3","article-title":"The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies","volume":"21","author":"Kumagai","year":"2020","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib14","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.1158\/0008-5472.CAN-22-0112","article-title":"Single-Cell Analysis Reveals a CD4+ T-cell Cluster That Correlates with PD-1 Blockade Efficacy","volume":"82","author":"Kagamu","year":"2022","journal-title":"Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2021.101480","article-title":"Emerging concepts in PD-1 checkpoint biology","volume":"52","author":"Pauken","year":"2021","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib16","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/s41586-019-1922-8","article-title":"B cells and tertiary lymphoid structures promote immunotherapy response","volume":"577","author":"Helmink","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ccell.2026.07.001_bib17","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.cell.2019.10.028","article-title":"B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer","volume":"179","author":"Hollern","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005531","article-title":"Maturation and abundance of tertiary lymphoid structures are associated with the efficacy of neoadjuvant chemoimmunotherapy in resectable non-small cell lung cancer","volume":"10","author":"Sun","year":"2022","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib19","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/s43018-021-00232-6","article-title":"Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression","volume":"2","author":"Vanhersecke","year":"2021","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib20","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2024-010395","article-title":"Perioperative pembrolizumab in early-stage non-small cell lung cancer (NSCLC): safety, efficacy, and exploratory biomarker analysis","volume":"13","author":"Wood","year":"2025","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib21","doi-asserted-by":"crossref","DOI":"10.1126\/science.adj4857","article-title":"A blueprint for tumor-infiltrating B cells across human cancers","volume":"384","author":"Ma","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.ccell.2026.07.001_bib22","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1158\/0008-5472.CAN-20-2701","article-title":"Mesothelin-Specific CAR T Cells Target Ovarian Cancer","volume":"81","author":"Schoutrop","year":"2021","journal-title":"Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib23","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jtcvs.2021.02.099","article-title":"Perioperative outcomes of pulmonary resection after neoadjuvant pembrolizumab in patients with non-small cell lung cancer","volume":"163","author":"Tong","year":"2022","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.ccell.2026.07.001_bib24","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2025-012432","article-title":"Perioperative pembrolizumab in early-stage non-small cell lung cancer (NSCLC): conventional and distribution-based immune profiling of the tumor microenvironment and peripheral circulation","volume":"13","author":"Zhang","year":"2025","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib25","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.immuni.2024.01.006","article-title":"An atlas of cells in the human tonsil","volume":"57","author":"Massoni-Badosa","year":"2024","journal-title":"Immunity"},{"key":"10.1016\/j.ccell.2026.07.001_bib26","doi-asserted-by":"crossref","first-page":"7682","DOI":"10.1038\/s41467-023-43504-8","article-title":"The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome","volume":"14","author":"Al-Aubodah","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ccell.2026.07.001_bib27","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.adj4748","article-title":"Zeb2 drives the formation of CD11c(+) atypical B cells to sustain germinal centers that control persistent infection","volume":"9","author":"Gao","year":"2024","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib28","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/s41591-025-04177-6","article-title":"Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade","volume":"32","author":"Gonzalez-Kozlova","year":"2026","journal-title":"Nat. Med."},{"key":"10.1016\/j.ccell.2026.07.001_bib29","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1158\/0008-5472.CAN-15-1085","article-title":"Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity","volume":"76","author":"Brentville","year":"2016","journal-title":"Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib30","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-002549","article-title":"Protein citrullination as a source of cancer neoantigens","volume":"9","author":"Katayama","year":"2021","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib31","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1158\/0008-5472.CAN-18-2797","article-title":"Citrullination in Cancer","volume":"79","author":"Yuzhalin","year":"2019","journal-title":"Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2022.982593","article-title":"Targeting extracellular Hsp90: A unique frontier against cancer","volume":"9","author":"Sager","year":"2022","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.ccell.2026.07.001_bib33","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.4049\/jimmunol.1600162","article-title":"Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes","volume":"197","author":"Travers","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib34","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1158\/0008-5472.CAN-15-1142","article-title":"Calreticulin Expression in Human Non-Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis","volume":"76","author":"Fucikova","year":"2016","journal-title":"Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib35","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41422-020-0383-9","article-title":"Calreticulin and cancer","volume":"31","author":"Fucikova","year":"2021","journal-title":"Cell Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib36","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.ccell.2023.04.015","article-title":"Calreticulin exposure orchestrates innate immunosurveillance","volume":"41","author":"Guilbaud","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/cells10010130","article-title":"Calreticulin-Multifunctional Chaperone in Immunogenic Cell Death: Potential Significance as a Prognostic Biomarker in Ovarian Cancer Patients","volume":"10","author":"Kielbik","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.ccell.2026.07.001_bib38","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.3899\/jrheum.131375","article-title":"Anticyclic citrullinated peptide antibodies in rheumatoid and nonrheumatoid rheumatic disorders: experience with 1162 patients","volume":"41","author":"Payet","year":"2015","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.ccell.2026.07.001_bib39","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/08916930400022707","article-title":"Multiplexed AtheNA multi-lyte immunoassay for ANA screening in autoimmune diseases","volume":"38","author":"Shovman","year":"2005","journal-title":"Autoimmunity"},{"key":"10.1016\/j.ccell.2026.07.001_bib40","doi-asserted-by":"crossref","DOI":"10.1126\/science.aab1253","article-title":"HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies","volume":"349","author":"Williams","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.ccell.2026.07.001_bib41","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1016\/j.cell.2021.04.042","article-title":"Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies","volume":"184","author":"Williams","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib42","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1006\/jmbi.1996.0425","article-title":"Structural aspects of the p53 protein in relation to gene evolution: a second look","volume":"260","author":"Soussi","year":"1996","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ccell.2026.07.001_bib43","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3389\/fcell.2017.00096","article-title":"Calreticulin: Challenges Posed by the Intrinsically Disordered Nature of Calreticulin to the Study of Its Function","volume":"5","author":"Varricchio","year":"2017","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.ccell.2026.07.001_bib44","doi-asserted-by":"crossref","first-page":"6829","DOI":"10.18632\/oncotarget.27332","article-title":"Post-translational modifications of vimentin reflect different pathological processes associated with non-small cell lung cancer and chronic obstructive pulmonary disease","volume":"10","author":"Nissen","year":"2019","journal-title":"Oncotarget"},{"key":"10.1016\/j.ccell.2026.07.001_bib45","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1158\/2159-8290.CD-24-1515","article-title":"Eradicating Drug-tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T Cellular Therapy","volume":"15","author":"Baldacci","year":"2025","journal-title":"Cancer Discov."},{"key":"10.1016\/j.ccell.2026.07.001_bib46","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.539654","article-title":"4-1BB Signaling Boosts the Anti-Tumor Activity of CD28-Incorporated 2(nd) Generation Chimeric Antigen Receptor-Modified T Cells","volume":"11","author":"Dai","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib47","doi-asserted-by":"crossref","first-page":"4014","DOI":"10.1158\/1078-0432.CCR-18-2559","article-title":"Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells","volume":"25","author":"Drent","year":"2019","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib48","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13051050","article-title":"CD28 Co-Stimulus Achieves Superior CAR T Cell Effector Function against Solid Tumors Than 4-1BB Co-Stimulus","volume":"13","author":"Textor","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.ccell.2026.07.001_bib49","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1016\/j.immuni.2023.09.013","article-title":"Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers","volume":"56","author":"Biswas","year":"2023","journal-title":"Immunity"},{"key":"10.1016\/j.ccell.2026.07.001_bib50","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/nm1097","article-title":"Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A","volume":"10","author":"Conejo-Garcia","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.ccell.2026.07.001_bib51","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1158\/1078-0432.CCR-16-0492","article-title":"Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target","volume":"23","author":"Perales-Puchalt","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib52","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.immuni.2021.12.007","article-title":"TGF-\u03b2-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures","volume":"55","author":"Chaurio","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.ccell.2026.07.001_bib53","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-004885","article-title":"Baseline circulating unswitched memory B cells and B-cell related soluble factors are associated with overall survival in patients with clear cell renal cell carcinoma treated with nivolumab within the NIVOREN GETUG-AFU 26 study","volume":"10","author":"Carril-Ajuria","year":"2022","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib54","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2018.1513440","article-title":"A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy","volume":"8","author":"Varn","year":"2019","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.ccell.2026.07.001_bib55","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.759217","article-title":"Predictable Roles of Peripheral IgM Memory B Cells for the Responses to Anti-PD-1 Monotherapy Against Advanced Non-Small Cell Lung Cancer","volume":"12","author":"Xia","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib56","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.908034","article-title":"Alternative B Cell Differentiation During Infection and Inflammation","volume":"13","author":"Courey-Ghaouzi","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib57","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13073-023-01164-9","article-title":"Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing","volume":"15","author":"Hu","year":"2023","journal-title":"Genome Med."},{"key":"10.1016\/j.ccell.2026.07.001_bib58","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/s41586-025-09188-4","article-title":"Humoral determinants of checkpoint immunotherapy","volume":"644","author":"Dai","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.ccell.2026.07.001_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2020.101393","article-title":"Post-translational modifications such as citrullination are excellent targets for cancer therapy","volume":"47","author":"Brentville","year":"2020","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib60","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2017.1390642","article-title":"Citrullinated \u03b1-enolase is an effective target for anti-cancer immunity","volume":"7","author":"Cook","year":"2018","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.ccell.2026.07.001_bib61","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1186\/1477-7819-11-260","article-title":"Investigating citrullinated proteins in tumour cell lines","volume":"11","author":"Jiang","year":"2013","journal-title":"World J. Surg. Oncol."},{"key":"10.1016\/j.ccell.2026.07.001_bib62","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1084\/jem.20110640","article-title":"Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells","volume":"208","author":"Ireland","year":"2011","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ccell.2026.07.001_bib63","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/nrc1692","article-title":"The role of autophagy in cancer development and response to therapy","volume":"5","author":"Kondo","year":"2005","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ccell.2026.07.001_bib64","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.lfs.2017.08.029","article-title":"Autophagy: The spotlight for cellular stress responses","volume":"188","author":"Ravanan","year":"2017","journal-title":"Life Sci."},{"key":"10.1016\/j.ccell.2026.07.001_bib65","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.3899\/jrheum.131375","article-title":"Anticyclic citrullinated peptide antibodies in rheumatoid and nonrheumatoid rheumatic disorders: experience with 1162 patients","volume":"41","author":"Payet","year":"2014","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.ccell.2026.07.001_bib66","article-title":"Anti-Citrullinated Protein Antibodies in Patients with Rheumatoid Arthritis: Biological Effects and Mechanisms of Immunopathogenesis","volume":"21","author":"Wu","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ccell.2026.07.001_bib67","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1038\/s41467-023-39042-y","article-title":"B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma","volume":"14","author":"Crescioli","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ccell.2026.07.001_bib68","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41587-023-01767-y","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","volume":"42","author":"Hao","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.ccell.2026.07.001_bib69","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ccell.2026.07.001_bib70","doi-asserted-by":"crossref","first-page":"47","DOI":"10.12688\/f1000research.22139.1","article-title":"scRepertoire: An R-based toolkit for single-cell immune receptor analysis","volume":"9","author":"Borcherding","year":"2020","journal-title":"F1000Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib71","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.3389\/fimmu.2017.01407","article-title":"Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies","volume":"8","author":"Ramesh","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ccell.2026.07.001_bib72","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1093\/bioinformatics\/btv359","article-title":"Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data","volume":"31","author":"Gupta","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ccell.2026.07.001_bib73","doi-asserted-by":"crossref","first-page":"W34","DOI":"10.1093\/nar\/gkt382","article-title":"IgBLAST: an immunoglobulin variable domain sequence analysis tool","volume":"41","author":"Ye","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ccell.2026.07.001_bib74","doi-asserted-by":"crossref","first-page":"6458","DOI":"10.1038\/s41467-022-34145-4","article-title":"Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications","volume":"13","author":"Ye","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ccell.2026.07.001_bib75","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0076-6879(97)76066-X","article-title":"Processing of X-ray diffraction data collected in oscillation mode","volume":"276","author":"Otwinowski","year":"1997","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.ccell.2026.07.001_bib76","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1107\/S0907444909052925","article-title":"PHENIX: a comprehensive Python-based system for macromolecular structure solution","volume":"66","author":"Adams","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.ccell.2026.07.001_bib77","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adu1823","article-title":"AbEpiTope-1.0: Improved antibody target prediction by use of AlphaFold and inverse folding","volume":"11","author":"Clifford","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ccell.2026.07.001_bib78","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ccell.2026.07.001_bib79","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ccell.2022.03.008","article-title":"Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells","volume":"40","author":"Anadon","year":"2022","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ccell.2026.07.001_bib80","doi-asserted-by":"crossref","first-page":"3802","DOI":"10.1038\/s41596-021-00556-8","article-title":"CODEX multiplexed tissue imaging with DNA-conjugated antibodies","volume":"16","author":"Black","year":"2021","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ccell.2026.07.001_bib81","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aai7521","article-title":"Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide","volume":"9","author":"Alam","year":"2017","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.ccell.2026.07.001_bib82","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1107\/S0021889807021206","article-title":"Phaser crystallographic software","volume":"40","author":"McCoy","year":"2007","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.ccell.2026.07.001_bib83","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1107\/S0907444912001308","article-title":"Towards automated crystallographic structure refinement with phenix.refine","volume":"68","author":"Afonine","year":"2012","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.ccell.2026.07.001_bib84","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1107\/S0907444910007493","article-title":"Features and development of Coot","volume":"66","author":"Emsley","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.ccell.2026.07.001_bib85","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1107\/S0907444909047337","article-title":"XDS","volume":"66","author":"Kabsch","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.ccell.2026.07.001_bib86","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/COH.0000000000000423","article-title":"Cross-reactivity of HIV vaccine responses and the microbiome","volume":"13","author":"Williams","year":"2018","journal-title":"Curr. Opin. HIV AIDS"}],"container-title":["Cancer Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535610826003107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535610826003107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:31:59Z","timestamp":1789399919000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1535610826003107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":86,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1535610826003107"],"URL":"https:\/\/doi.org\/10.1016\/j.ccell.2026.07.001","relation":{},"ISSN":["1535-6108"],"issn-type":[{"value":"1535-6108","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies","name":"articletitle","label":"Article Title"},{"value":"Cancer Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccell.2026.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.ccell.2026.06.020","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}