{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T02:44:30Z","timestamp":1773888270080,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","theclinics.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cardiology Clinics"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ccl.2024.02.003","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T21:44:45Z","timestamp":1709415885000},"page":"559-571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patent Foramen Ovale and Coronary Artery Spasm"],"prefix":"10.1016","volume":"42","author":[{"given":"Deepak","family":"Ravi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rushi V.","family":"Parikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamil A.","family":"Aboulhosn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan M.","family":"Tobis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ccl.2024.02.003_bib1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1474-4422(17)30435-0","article-title":"The pathophysiology of migraine: implications for clinical management","volume":"17","author":"Charles","year":"2018","journal-title":"Lancet Neurol"},{"issue":"1","key":"10.1016\/j.ccl.2024.02.003_bib2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s10072-015-2163-8","article-title":"Migraine with aura and patent foramen ovale: myth or reality?","volume":"36","author":"Finocchi","year":"2015","journal-title":"Neurol Sci"},{"issue":"3","key":"10.1016\/j.ccl.2024.02.003_bib3","first-page":"e108","article-title":"How the heart whispers to the brain: serotonin as neurovascular mediator in patent foramen ovale related stroke","volume":"42","author":"Ning","year":"2011","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.ccl.2024.02.003_bib4","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/head.13044","article-title":"Hypercoagulability and migraine. Headache","volume":"58","author":"Tietjen","year":"2018","journal-title":"The Journal of Head and Face Pain"},{"key":"10.1016\/j.ccl.2024.02.003_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2020.543485","article-title":"The correlation between migraine and patent foramen ovale","volume":"11","author":"Liu","year":"2020","journal-title":"Front Neurol"},{"key":"10.1016\/j.ccl.2024.02.003_bib6","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.amjmed.2013.12.006","article-title":"Patent foramen ovale and migraine attacks: a systematic review","volume":"127","author":"Lip","year":"2014","journal-title":"Am J Med"},{"key":"10.1016\/j.ccl.2024.02.003_bib7","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1468-2982.2008.01554.x","article-title":"Patent foramen ovale and migraine: a quantitative systemic review","volume":"28","author":"Schwedt","year":"2008","journal-title":"Cephalalgia"},{"key":"10.1016\/j.ccl.2024.02.003_bib8","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1212\/01.wnl.0000179800.73706.20","article-title":"Prevalence and size of directly detected patent foramen ovale in migraine with aura","volume":"65","author":"Schwerzmann","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.ccl.2024.02.003_bib9","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1212\/01.wnl.0000201271.75157.5a","article-title":"Different degrees of right-to-left shunting predict migraine and stroke: data from 420 patients","volume":"66","author":"Anzola","year":"2006","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.ccl.2024.02.003_bib10","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1136\/jim-2020-001342","article-title":"Clopidogrel can be an effective complementary prophylactic for drug-refractory migraine with patent foramen ovale","volume":"68","author":"Guo","year":"2020","journal-title":"J\u00a0Investig Med"},{"key":"10.1016\/j.ccl.2024.02.003_bib11","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/2118740","article-title":"Platelet p2y12 inhibitor in the treatment and prevention of migraine: a systematic review and meta-analysis","volume":"2022","author":"Wang","year":"2022","journal-title":"Behav Neurol"},{"issue":"20","key":"10.1016\/j.ccl.2024.02.003_bib12","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1001\/jama.2015.13919","article-title":"Effect of clopidogrel and aspirin vs aspirin alone on migraine headaches after transcatheter atrial septal defect closure: the canoa randomized clinical trial","volume":"314","author":"Rod\u00e9s-Cabau","year":"2015","journal-title":"JAMA"},{"issue":"11","key":"10.1016\/j.ccl.2024.02.003_bib13","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1161\/CIRCULATIONAHA.107.727271","volume":"117","author":"Dowson","year":"2008","journal-title":"Circulation"},{"issue":"26","key":"10.1016\/j.ccl.2024.02.003_bib14","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1093\/eurheartj\/ehw027","article-title":"Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial","volume":"37","author":"Mattle","year":"2016","journal-title":"Eur Heart J"},{"issue":"22","key":"10.1016\/j.ccl.2024.02.003_bib15","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1016\/j.jacc.2017.09.1105","article-title":"Percutaneous closure of patent foramen ovale in patients with migraine: the PREMIUM trial","volume":"70","author":"Tobis","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.ccl.2024.02.003_bib16","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.jacc.2020.11.068","article-title":"Pooled analysis of PFO occluder device trials in patients with PFO and migraine","volume":"77","author":"Mojadidi","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"17","key":"10.1016\/j.ccl.2024.02.003_bib17","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1016\/j.jacc.2015.08.876","article-title":"Emergence of Nonobstructive coronary artery disease: a Woman\u2019s Problem and need for change in Definition on angiography","volume":"66","author":"Pepine","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"23_Part_A","key":"10.1016\/j.ccl.2024.02.003_bib18","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1016\/j.jacc.2018.09.006","article-title":"Stratified medical therapy using invasive coronary function testing in angina","volume":"72","author":"Ford Thomas","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.ccl.2024.02.003_bib19","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1212\/WNL.0b013e3182a08d59","article-title":"An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke","volume":"81","author":"Kent","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.ccl.2024.02.003_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/5894586","article-title":"Coronary artery spasm: new insights","volume":"2020","author":"Matta","year":"2020","journal-title":"J\u00a0Interv Cardiol"},{"issue":"14","key":"10.1016\/j.ccl.2024.02.003_bib21","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jacc.2021.08.028","article-title":"Assessing microvascular dysfunction in angina with Unobstructed coronary arteries: JACC review Topic of the Week","volume":"78","author":"Jansen","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ccl.2024.02.003_bib22","unstructured":"Minoca from a to z. American College of Cardiology.2022. Available at: https:\/\/www.acc.org\/Latest-in-Cardiology\/Articles\/2022\/01\/05\/17\/41\/MINOCA-from-A-to-Z."},{"issue":"45","key":"10.1016\/j.ccl.2024.02.003_bib23","doi-asserted-by":"crossref","first-page":"3134","DOI":"10.1093\/eurheartj\/ehv100","article-title":"Coronary vascular regulation, remodelling, and collateralization: mechanisms and clinical implications on behalf of the working group on coronary pathophysiology and microcirculation","volume":"36","author":"Pries","year":"2015","journal-title":"Eur Heart J"},{"issue":"15","key":"10.1016\/j.ccl.2024.02.003_bib24","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.4244\/EIJ-D-21-00402","article-title":"Principles and pitfalls in coronary vasomotor function testing","volume":"17","author":"Feenstra","year":"2022","journal-title":"EuroIntervention"},{"issue":"3","key":"10.1016\/j.ccl.2024.02.003_bib25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ccl.2024.02.003_bib26","article-title":"A\u00a0new syndrome of patent foramen ovale inducing vasospastic angina and migraine","volume":"28","author":"Ravi","year":"2023","journal-title":"JACC (J Am Coll Cardiol): Case Reports"},{"issue":"1","key":"10.1016\/j.ccl.2024.02.003_bib27","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0735-1097(01)01316-X","article-title":"Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction","volume":"38","author":"Tsuchihashi","year":"2001","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"24","key":"10.1016\/j.ccl.2024.02.003_bib28","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1161\/CIRCULATIONAHA.116.027121","article-title":"Pathophysiology of takotsubo syndrome","volume":"135","author":"Pelliccia","year":"2017","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.ccl.2024.02.003_bib29","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1067\/mhj.2002.120403","article-title":"Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction","volume":"143","author":"Kurisu","year":"2002","journal-title":"Am Heart J"},{"issue":"3","key":"10.1016\/j.ccl.2024.02.003_bib30","article-title":"Pathophysiology of takotsubo cardiomyopathy: reopened debate","volume":"48","author":"Angelini","year":"2021","journal-title":"Tex Heart Inst J"},{"issue":"3","key":"10.1016\/j.ccl.2024.02.003_bib31","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/ccd.21338","article-title":"Transient left ventricular apical ballooning: a unifying pathophysiologic theory at the edge of Prinzmetal angina","volume":"71","author":"Angelini","year":"2008","journal-title":"Cathet Cardiovasc Intervent"},{"issue":"4","key":"10.1016\/j.ccl.2024.02.003_bib32","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1253\/circj.71.565","article-title":"Chronic estrogen supplementation following ovariectomy improves the emotional stress-induced cardiovascular responses by indirect action on the nervous system and by direct action on the heart","volume":"71","author":"Ueyama","year":"2007","journal-title":"Circ J"},{"issue":"6","key":"10.1016\/j.ccl.2024.02.003_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ehjcr\/ytaa407","article-title":"Reverse takotsubo cardiomyopathy caused by patent foramen ovale-related cryptogenic stroke: a case report","volume":"4","author":"Takafuji","year":"2020","journal-title":"Eur Heart J Case Rep"}],"container-title":["Cardiology Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733865124000134?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733865124000134?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T23:18:35Z","timestamp":1727133515000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733865124000134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S0733865124000134"],"URL":"https:\/\/doi.org\/10.1016\/j.ccl.2024.02.003","relation":{},"ISSN":["0733-8651"],"issn-type":[{"value":"0733-8651","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patent Foramen Ovale and Coronary Artery Spasm","name":"articletitle","label":"Article Title"},{"value":"Cardiology Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccl.2024.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}