{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T01:10:07Z","timestamp":1759453807174,"version":"build-2065373602"},"reference-count":70,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Chest Medicine"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.ccm.2015.05.011","type":"journal-article","created":{"date-parts":[[2015,7,8]],"date-time":"2015-07-08T09:10:41Z","timestamp":1436346641000},"page":"385-400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Novel Uses of Targeted Temperature Management"],"prefix":"10.1016","volume":"36","author":[{"given":"John","family":"McGinniss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyoko","family":"Honiden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ccm.2015.05.011_bib1","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1378\/chest.07-2190","article-title":"Therapeutic hypothermia: past, present, and future","volume":"133","author":"Varon","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.ccm.2015.05.011_bib2","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1097\/CCM.0b013e318206bab2","article-title":"Targeted temperature management in critical care: a report and recommendations from five professional societies","volume":"39","author":"Nunnally","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib3","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1213\/00000539-195911000-00010","article-title":"The use of hypothermia after cardiac arrest","volume":"38","author":"Benson","year":"1959","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ccm.2015.05.011_bib4","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJMoa012689","article-title":"Mild hypothermia to improve the neurological outcome after cardiac arrest","volume":"346","author":"The Hypothermia After Cardiac Arrest Study Group","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib5","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/NRL.0b013e318224ee0e","article-title":"Neurological prognosis in cardiac arrest patients treated with therapeutic hypothermia","volume":"17","author":"Blondin","year":"2011","journal-title":"Neurologist"},{"key":"10.1016\/j.ccm.2015.05.011_bib6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa003289","article-title":"Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia","volume":"346","author":"Bernard","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib7","doi-asserted-by":"crossref","first-page":"S768","DOI":"10.1161\/CIRCULATIONAHA.110.971002","article-title":"Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","volume":"122","author":"Peberdy","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ccm.2015.05.011_bib8","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1161\/CIRCULATIONAHA.114.009711","article-title":"Recent trends in survival from out-of-hospital cardiac arrest in the United States","volume":"130","author":"Chan","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.ccm.2015.05.011_bib9","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1378\/chest.12-3025","article-title":"Clinical applications of targeted temperature management","volume":"145","author":"Perman","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.ccm.2015.05.011_bib10","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1161\/CIRCULATIONAHA.111.076851","article-title":"Therapeutic hypothermia","volume":"127","author":"Scirica","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.ccm.2015.05.011_bib11","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jacc.2011.06.077","article-title":"Hypothermia therapy: neurological and cardiac benefits","volume":"59","author":"Delhaye","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib12","doi-asserted-by":"crossref","first-page":"S186","DOI":"10.1097\/CCM.0b013e3181aa5241","article-title":"Mechanisms of action, physiological effects, and complications of hypothermia","volume":"37","author":"Poldermann","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib13","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1186\/s13054-014-0546-5","article-title":"Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study","volume":"18","author":"Bisschops","year":"2014","journal-title":"Crit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib14","doi-asserted-by":"crossref","first-page":"e67476","DOI":"10.1371\/journal.pone.0067476","article-title":"Effect of mild hypothermia on the coagulation-fibrinolysis system and physiological anticoagulants after cardiopulmonary resuscitation in a porcine model","volume":"8","author":"Gong","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ccm.2015.05.011_bib15","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1161\/CIRCULATIONAHA.110.987347","article-title":"Is hypothermia after cardiac arrest effective in both shockable and nonshockable patients?: Insights from a large registry","volume":"123","author":"Dumas","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ccm.2015.05.011_bib16","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.resuscitation.2011.07.031","article-title":"Does therapeutic hypothermia benefit adult cardiac arrest patients presenting with non-shockable rhythms?: A systematic review and meta-analysis of randomized and non-randomized studies","volume":"83","author":"Kim","year":"2012","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib17","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1097\/CCM.0000000000000543","article-title":"Safety, feasibility, and outcomes of induced hypothermia therapy following in-hospital cardiac arrest\u2014evaluation of a large prospective registry","volume":"42","author":"Dankiewicz","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib18","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/S0140-6736(98)12440-6","article-title":"Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure","volume":"354","author":"Jalan","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ccm.2015.05.011_bib19","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1053\/j.gastro.2004.08.005","article-title":"Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension","volume":"127","author":"Jalan","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ccm.2015.05.011_bib20","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1097\/CCM.0b013e31818029a3","article-title":"Results of a protocol for the management of patients with fulminant liver failure","volume":"36","author":"Raschke","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib21","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0140-6736(96)90008-2","article-title":"Body temperature in acute stroke: relation to stroke severity, infarct size, mortality and outcome","volume":"347","author":"Reith","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.ccm.2015.05.011_bib22","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.06.017","article-title":"Therapeutic hypothermia (different depths, durations, and rewarming speeds) for acute ischemic stroke: a meta-analysis","volume":"23","author":"Wan","year":"2014","journal-title":"J\u00a0Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.ccm.2015.05.011_bib23","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1227\/01.NEU.0000336312.32773.A0","article-title":"Therapeutic hypothermia in patients with aneurysmal subarachnoid hemorrhage, refractory intracranial hypertension, or cerebral vasospasm","volume":"64","author":"Seule","year":"2009","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ccm.2015.05.011_bib24","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s12028-012-9762-5","article-title":"Mild prolonged hypothermia for large intracerebral hemorrhage","volume":"18","author":"Staykov","year":"2013","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib25","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1056\/NEJM199702203360803","article-title":"Treatment of traumatic brain injury with moderate hypothermia","volume":"20","author":"Marion","year":"1997","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib26","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1056\/NEJM200102223440803","article-title":"Lack of effect of induction of hypothermia after acute brain injury","volume":"344","author":"Clifton","year":"2001","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1474-4422(10)70300-8","article-title":"Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial","volume":"10","author":"Clifton","year":"2011","journal-title":"Lancet Neurol"},{"issue":"2","key":"10.1016\/j.ccm.2015.05.011_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001048.pub3","article-title":"Hypothermia for traumatic head injury","author":"Sydenham","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ccm.2015.05.011_bib29","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.4244\/EIJV8I12A217","article-title":"A\u00a0pooled analysis of the effect of endovascular cooling on infarct size in patients with ST-elevation myocardial infarction","volume":"8","author":"Erlinge","year":"2013","journal-title":"EuroIntervention"},{"key":"10.1016\/j.ccm.2015.05.011_bib30","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1016\/j.jacc.2013.12.027","article-title":"Rapid endovascular catheter core cooling combined with cold saline as an adjunct to percutaneous coronary intervention for the treatment of acute myocardial infarction [CHILL-MI]","volume":"63","author":"Erlinge","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib31","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1097\/CCM.0b013e3182373174","article-title":"Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover","volume":"40","author":"Beurskens","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib32","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/CCM.0b013e3182373134","article-title":"Oxygen transport during experimental sepsis: effect of hypothermia","volume":"40","author":"L\u00e9on","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib33","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1164\/rccm.201110-1820OC","article-title":"Fever control using external cooling in septic shock: a randomized controlled trial","volume":"185","author":"Schortgen","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib34","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.trsl.2011.10.005","article-title":"Mild hypothermia reduces ventilator-induced lung injury, irrespective of reducing respiratory rate","volume":"159","author":"Aslami","year":"2012","journal-title":"Transl Res"},{"key":"10.1016\/j.ccm.2015.05.011_bib35","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0300-9572(93)90178-S","article-title":"Effects of induced hypothermia in patients with septic adult respiratory distress syndrome","volume":"26","author":"Villar","year":"1993","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib36","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1089\/ther.2014.0004","article-title":"Effect of therapeutic hypothermia on gas exchange and respiratory mechanics: a retrospective cohort study","volume":"4","author":"Karnatovskaia","year":"2014","journal-title":"Ther Hypothermia Temp Manag"},{"key":"10.1016\/j.ccm.2015.05.011_bib37","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1001\/jama.2013.280506","article-title":"Induced hypothermia in severe bacterial meningitis","volume":"310","author":"Mourvillier","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.ccm.2015.05.011_bib38","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/CCM.0b013e3182377038","article-title":"Induction of prehospital therapeutic hypothermia after resuscitation from nonventricular fibrillation cardiac arrest","volume":"40","author":"Bernard","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib39","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1056\/NEJMoa040975","article-title":"Mild intraoperative hypothermia during surgery for intracranial aneurysm","volume":"352","author":"Todd","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib40","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.amjcard.2011.04.026","article-title":"Systemic hypothermia to prevent radiocontrast nephropathy (from the COOL-RCN randomized trial)","volume":"108","author":"Stone","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib41","first-page":"594","article-title":"Salvage techniques in traumatic cardiac arrest: thoracotomy, extracorporeal life support, and therapeutic hypothermia","volume":"19","author":"Tisherman","year":"2013","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib42","doi-asserted-by":"crossref","first-page":"R91","DOI":"10.1186\/cc6104","article-title":"Comparison of cooling methods to induce and maintain normo- and hypothermia in intensive care unit patients: a prospective intervention study","volume":"11","author":"Hoedemaekers","year":"2007","journal-title":"Crit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib43","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/CCM.0b013e318206b80f","article-title":"A\u00a0comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors","volume":"39","author":"T\u00f8mte","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib44","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1097\/01.CCM.0000190427.88735.19","article-title":"Induction of hypothermia in patients with various types of neurological injury with use of large volumes of ice-cold intravenous fluid","volume":"33","author":"Polderman","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib45","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s00392-013-0572-3","article-title":"Invasive versus non-invasive cooling after in- and out-of-hospital cardiac arrest: a randomized trial","volume":"102","author":"Pittl","year":"2013","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib46","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1177\/000313480707300508","article-title":"Increased risk of deep venous thrombosis with endovascular cooling in patients with traumatic head injury","volume":"73","author":"Simosa","year":"2007","journal-title":"Am Surg"},{"key":"10.1016\/j.ccm.2015.05.011_bib47","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1161\/CIRCULATIONAHA.109.931691","article-title":"Intra-arrest transnasal evaporative cooling: a randomized prehospital, multicenter study (PRINCE: pre-ROSC intranasal cooling effectiveness)","volume":"122","author":"Castr\u00e9n","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ccm.2015.05.011_bib48","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1097\/CCM.0b013e31828a4337","article-title":"Feasibility and cardiac safety of inhaled xenon in combination with therapeutic hypothermia following out-of-hospital cardiac arrest","volume":"41","author":"Arola","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib49","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1001\/jama.2013.282173","article-title":"Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest","volume":"311","author":"Kim","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.ccm.2015.05.011_bib50","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ijcard.2007.12.039","article-title":"Early achievement of mild therapeutic hypothermia and the neurological outcome after cardiac arrest","volume":"133","author":"Wolff","year":"2009","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib51","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1186\/cc10116","article-title":"Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest","volume":"15","author":"Haugk","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib52","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1056\/NEJMoa1310519","article-title":"Targeted temperature management at 33\u00b0C versus 36\u00b0C after cardiac arrest","volume":"369","author":"Nielsen","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib53","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.resuscitation.2014.08.007","article-title":"The inflammatory response after out-of-hospital cardiac arrest is not modified by targeted temperature management at 33\u00b0C or 36\u00b0C","volume":"85","author":"Bro-Jeppesen","year":"2014","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib54","doi-asserted-by":"crossref","first-page":"e106","DOI":"10.1097\/CCM.0b013e3182a63fff","article-title":"The effects of the rate of postresuscitation rewarming following hypothermia on outcomes of cardiopulmonary resuscitation in a rat model","volume":"42","author":"Lu","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib55","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1016\/j.resuscitation.2012.04.006","article-title":"The influence of rewarming after therapeutic hypothermia on outcome after cardiac arrest","volume":"83","author":"Bouwes","year":"2012","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib56","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1016\/j.resuscitation.2013.07.023","article-title":"Post-hypothermia fever is associated with increased mortality after out-of-hospital cardiac arrest","volume":"84","author":"Bro-Jeppesen","year":"2013","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib57","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/CCM.0b013e3182a276e8","article-title":"Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis","volume":"42","author":"Geurts","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib58","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.resuscitation.2012.11.004","article-title":"Early antibiotics improve survival following out-of hospital cardiac arrest","volume":"84","author":"Davies","year":"2013","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib59","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1016\/j.resuscitation.2014.07.018","article-title":"Therapeutic temperature management after cardiac arrest and the risk of bleeding: systematic review and meta-analysis","volume":"85","author":"Stockmann","year":"2014","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib60","article-title":"The correlation between the amplitude of Osborn wave and core body temperature","author":"Omar","year":"2014","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib61","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/clc.22224","article-title":"Therapeutic hypothermia-induced electrocardiographic changes and relations to in-hospital mortality","volume":"37","author":"Lam","year":"2014","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.ccm.2015.05.011_bib62","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.resuscitation.2013.07.006","article-title":"The impact of severe acidemia on neurological outcome of cardiac arrest survivors undergoing therapeutic hypothermia","volume":"84","author":"Ganga","year":"2013","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib63","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.ajem.2014.05.004","article-title":"Association of blood glucose at admission with outcomes in patients treated with therapeutic hypothermia after cardiac arrest","volume":"32","author":"Kim","year":"2014","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib64","first-page":"586","article-title":"Evolution of insulin sensitivity and its variability in out-of-hospital cardiac arrest (OHCA) patients treated with hypothermia","volume":"18","author":"Sah Pri","year":"2014","journal-title":"Crit Care"},{"key":"10.1016\/j.ccm.2015.05.011_bib65","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1089\/ther.2013.0015","article-title":"Urine output changes during postcardiac arrest therapeutic hypothermia","volume":"3","author":"Raper","year":"2013","journal-title":"Ther Hypothermia Temp Manag"},{"key":"10.1016\/j.ccm.2015.05.011_bib66","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1212\/01.wnl.0000227183.21314.cd","article-title":"Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review)","volume":"67","author":"Wijdicks","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.ccm.2015.05.011_bib67","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.resuscitation.2013.10.030","article-title":"Awakening after cardiac arrest and post resuscitation hypothermia: are we pulling the plug too early?","volume":"85","author":"Gold","year":"2014","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib68","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.resuscitation.2013.10.031","article-title":"Quality of evidence in studies evaluating neuroimaging for neurological prognostication in adult patients resuscitated from cardiac arrest","volume":"85","author":"Hahn","year":"2014","journal-title":"Resuscitation"},{"key":"10.1016\/j.ccm.2015.05.011_bib69","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1097\/CCM.0000000000000211","article-title":"Early multimodal outcome prediction after cardiac arrest in patients treated with hypothermia","volume":"42","author":"Oddo","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.ccm.2015.05.011_bib70","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1007\/s00134-014-3470-x","article-title":"Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine","volume":"40","author":"Sandroni","year":"2014","journal-title":"Intensive Care Med"}],"container-title":["Clinics in Chest Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272523115000726?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272523115000726?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:51:25Z","timestamp":1759452685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272523115000726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":70,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0272523115000726"],"URL":"https:\/\/doi.org\/10.1016\/j.ccm.2015.05.011","relation":{},"ISSN":["0272-5231"],"issn-type":[{"type":"print","value":"0272-5231"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel Uses of Targeted Temperature Management","name":"articletitle","label":"Article Title"},{"value":"Clinics in Chest Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ccm.2015.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}