{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T14:54:05Z","timestamp":1781016845319,"version":"3.54.1"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["contemporaryclinicaltrials.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.cct.2016.12.003","type":"journal-article","created":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T17:47:00Z","timestamp":1481219220000},"page":"36-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Effectiveness of adjunctive, personalised psychosocial intervention for non-response to opioid agonist treatment: Study protocol for a pragmatic randomised controlled trial"],"prefix":"10.1016","volume":"53","author":[{"given":"John","family":"Marsden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garry","family":"Stillwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Hellier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Byford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kelleher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Shearer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Mitcheson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cct.2016.12.003_bb0005","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0140-6736(11)61138-0","article-title":"Extent of illicit drug use and dependence, and their contribution to the global burden of disease","volume":"379","author":"Degenhardt","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.cct.2016.12.003_bb0010","series-title":"Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV)","author":"American Psychiatric Association","year":"1994"},{"key":"10.1016\/j.cct.2016.12.003_bb0015","series-title":"Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence","author":"Mattick","year":"2009"},{"key":"10.1016\/j.cct.2016.12.003_bb0020","series-title":"Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence","author":"Mattick","year":"2014"},{"key":"10.1016\/j.cct.2016.12.003_bb0025","series-title":"Oral substitution treatment of injecting opioid users for prevention of HIV infection","author":"Gowing","year":"2011"},{"key":"10.1016\/j.cct.2016.12.003_bb0030","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0740-5472(98)00037-3","article-title":"Matching clients' needs with drug treatment services","volume":"16","author":"Hser","year":"1999","journal-title":"J. Subst. Abuse Treat."},{"key":"10.1016\/j.cct.2016.12.003_bb0035","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1360-0443.2003.00296.x","article-title":"The National Treatment Outcome Research Study (NTORS): 4\u20135year follow-up results","volume":"98","author":"Gossop","year":"2003","journal-title":"Addiction"},{"key":"10.1016\/j.cct.2016.12.003_bb0040","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/S0140-6736(09)61420-3","article-title":"Effectiveness of community treatments for heroin and crack cocaine addiction in England: a prospective, in-treatment cohort study","volume":"374","author":"Marsden","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.cct.2016.12.003_bb0045","series-title":"Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence","author":"Amato","year":"2011"},{"key":"10.1016\/j.cct.2016.12.003_bb0050","series-title":"Development of the Addiction Dimensions for Assessment and Personalised Treatment (ADAPT), Drug Alcohol Dependence","first-page":"121","volume":"139","author":"Marsden","year":"2014"},{"key":"10.1016\/j.cct.2016.12.003_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.a2390","article-title":"Improving the reporting of pragmatic trials: an extension of the CONSORT statement","volume":"337","author":"Zwarenstein","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.cct.2016.12.003_bb0060","series-title":"Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide","first-page":"1","volume":"2358","author":"Hoffmann","year":"2014"},{"key":"10.1016\/j.cct.2016.12.003_bb0065","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1111\/j.1360-0443.2008.02284.x","article-title":"Development of the treatment outcomes profile","volume":"103","author":"Marsden","year":"2008","journal-title":"Addiction"},{"key":"10.1016\/j.cct.2016.12.003_bb0070","series-title":"Timeline Followback: A Calendar Method for Assessing Alcohol and Drug Use. User's Guide","author":"Sobell","year":"1996"},{"key":"10.1016\/j.cct.2016.12.003_bb0075","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0924-9338(97)83297-X","article-title":"Reliability and Validity of the MINI International Neuropsychiatric Interview (M.I.N.I.): according to the SCID-P","volume":"12","author":"Sheehan","year":"1997","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0080","series-title":"The World Health Organization World Mental Health 2000 Initiative","first-page":"195","volume":"241","author":"Kessler","year":"2000"},{"key":"10.1016\/j.cct.2016.12.003_bb0085","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1006\/jrpe.2000.2302","article-title":"Refining the Architecture of Aggression: A Measurement Model for the Buss\u2013Perry Aggression Questionnaire","volume":"35","author":"Bryant","year":"2001","journal-title":"J. Res. Pers."},{"key":"10.1016\/j.cct.2016.12.003_bb0090","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1037\/0022-3514.63.3.452","article-title":"The aggression questionnaire","volume":"63","author":"Buss","year":"1992","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.cct.2016.12.003_bb0095","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1","article-title":"Factor structure of the Barratt impulsiveness scale","volume":"51","author":"Patton","year":"1995","journal-title":"J. Clin. Psychol."},{"key":"10.1016\/j.cct.2016.12.003_bb0100","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment (MoCA): a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cct.2016.12.003_bb0105","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/0010-440X(91)90066-L","article-title":"The measurement of craving in cocaine patients using the Minnesota Cocaine Craving Scale","volume":"32","author":"Halikas","year":"1991","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0110","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"169","author":"Kroenke","year":"2001","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.cct.2016.12.003_bb0115","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalised anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.cct.2016.12.003_bb0120","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1192\/bjp.180.5.461","article-title":"The Work and Social Adjustment Scale: a simple measure of impairment in functioning","volume":"180","author":"Mundt","year":"2002","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0125","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1192\/bjp.bp.112.111583","article-title":"Cost-effectiveness of injectable opioid treatment v. oral methadone for chronic heroin addiction","volume":"203","author":"Byford","year":"2013","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0130","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0168-8510(96)00822-6","article-title":"EuroQol: the current state of play","volume":"37","author":"Brooks","year":"1996","journal-title":"Health Policy"},{"key":"10.1016\/j.cct.2016.12.003_bb0135","first-page":"3","article-title":"The session rating scale: preliminary psychometric properties of a \u201cworking\u201d alliance measure","volume":"3","author":"Duncan","year":"2003","journal-title":"J. of Brief Ther."},{"key":"10.1016\/j.cct.2016.12.003_bb0140","first-page":"91","article-title":"The Outcome Rating Scale: a preliminary study of the reliability, validity, and feasibility of a brief visual analog measure","volume":"2","author":"Miller","year":"2003","journal-title":"J. of Brief Ther."},{"key":"10.1016\/j.cct.2016.12.003_bb0145","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.drugalcdep.2011.04.004","article-title":"Thirty-year trajectories of heroin and other drug use among men and women sampled from methadone treatment in California","volume":"118","author":"Grella","year":"2011","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2016.12.003_bb0150","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1081\/ADA-120001281","article-title":"Determining predictors of attrition in an outpatient substance abuse program","volume":"28","author":"Sayre","year":"2002","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.cct.2016.12.003_bb0155","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1037\/0022-006X.65.4.673","article-title":"Natural classes of treatment response","volume":"65","author":"Morral","year":"1997","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.cct.2016.12.003_bb0160","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1037\/0022-006X.62.6.1141","article-title":"Similarity of outcome predictors across opiate cocaine and alcohol treatments: role of treatment services","volume":"62","author":"McLellan","year":"1997","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.cct.2016.12.003_bb0165","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1111\/j.1360-0443.2012.03971.x","article-title":"Risk adjustment of heroin treatment outcomes for comparative performance assessment in England","volume":"107","author":"Marsden","year":"2012","journal-title":"Addiction"},{"key":"10.1016\/j.cct.2016.12.003_bb0170","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0376-8716(92)90101-H","article-title":"Cocaine use and HIV risk behavior in methadone maintenance patients","volume":"29","author":"Bux","year":"1992","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2016.12.003_bb0175","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.drugalcdep.2005.08.010","article-title":"The effect of persistence of cocaine use on 12-month outcomes for the treatment of heroin dependence","volume":"81","author":"Williamson","year":"2006","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2016.12.003_bb0180","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.3109\/10826089809059334","article-title":"Temporal patterns of heroin and cocaine use among methadone patients","volume":"33","author":"Magura","year":"1998","journal-title":"Subst. Use Misuse"},{"key":"10.1016\/j.cct.2016.12.003_bb0185","first-page":"791","article-title":"Psychiatric comorbidity measures as predictors of retention in drug abuse treatment programs","volume":"34","author":"Broome","year":"1999","journal-title":"Health Serv. Res."},{"key":"10.1016\/j.cct.2016.12.003_bb0190","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jsat.2006.03.014","article-title":"Physical health as a motivator for substance abuse treatment among medically ill adults: is it enough to keep them in treatment","volume":"31","author":"O'Toole","year":"2006","journal-title":"J. Subst. Abuse Treat."},{"issue":"Supplement 8","key":"10.1016\/j.cct.2016.12.003_bb0195","first-page":"5","article-title":"Treatment of patients with substance use disorders","volume":"163","author":"Kleber","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0200","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1037\/a0015252","article-title":"Changing network support for drinking: network support project 2-year follow-up","volume":"77","author":"Litt","year":"2009","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.cct.2016.12.003_bb0205","series-title":"Motivational Interviewing: Helping People Change (Applications of Motivational Interviewing)","author":"Miller","year":"2012"},{"key":"10.1016\/j.cct.2016.12.003_bb0210","series-title":"A picture is worth a thousand words: the case for graphic representations, Professional Psychology: Research and Practice","first-page":"104","volume":"40","author":"Dansereau","year":"2009"},{"key":"10.1016\/j.cct.2016.12.003_bb0215","unstructured":"National Institute for Health and Clinical Excellence. Psychosocial interventions. National Clinical Practice Guideline Number 51. 2008. NICE (CG51)."},{"key":"10.1016\/j.cct.2016.12.003_bb0220","doi-asserted-by":"crossref","unstructured":"Mitcheson L., Maslin J., Meynen T., Morrison T., Hill R., Wanigaratne S. Applied cognitive and behavioural approaches to the treatment of addiction: a practical treatment guide. Chichester: Wiley-Blackwell. 2010.","DOI":"10.1002\/9780470661420"},{"key":"10.1016\/j.cct.2016.12.003_bb0225","unstructured":"Higgins S.T., Silberman, S.H., Heil S.H. Contingency management in substance abuse treatment. New York, Guilford Press."},{"key":"10.1016\/j.cct.2016.12.003_bb0230","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1151\/spp042230","article-title":"Behavioral couples therapy for substance abuse: rationale, methods, and findings","volume":"2","author":"Fals-Stewart","year":"2004","journal-title":"Sci. Pract. Perspect."},{"key":"10.1016\/j.cct.2016.12.003_bb0235","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0306-4603(01)00176-9","article-title":"Social behaviour and network therapy - basic principles and early experiences","volume":"27","author":"Copello","year":"2002","journal-title":"Addict. Behav."},{"key":"10.1016\/j.cct.2016.12.003_bb0240","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.addbeh.2005.06.005","article-title":"Implementing and evaluating social behaviour and network therapy in drug treatment practice in the UK: a feasibility study","volume":"31","author":"Copello","year":"2006","journal-title":"Addict. Behav."},{"key":"10.1016\/j.cct.2016.12.003_bb0245","series-title":"Twelve step facilitation therapy manual. A clinical research guide for therapists treating individuals with alcohol abuse and dependence. National Institute on Alcohol Abuse and Alcoholism Project MATCH Monograph Series Volume 1","author":"Nowinski","year":"1999"},{"issue":"Suppl. 1","key":"10.1016\/j.cct.2016.12.003_bb0250","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1360-0443.2007.01773.x","article-title":"\u201cTweaking 12-step\u201d: the potential role of 12-Step self-help group involvement in methamphetamine recovery","volume":"102","author":"Donovan","year":"2007","journal-title":"Addiction"},{"key":"10.1016\/j.cct.2016.12.003_bb0255","series-title":"Overcoming depression. A self-help guide using cognitive behavioural techniques","author":"Gilbert","year":"2009"},{"key":"10.1016\/j.cct.2016.12.003_bb0260","series-title":"Collaborative Case Conceptualization: Working Effectively With Clients in Cognitive-behavioral Therapy","author":"Kuyken","year":"2009"},{"key":"10.1016\/j.cct.2016.12.003_bb0265","series-title":"Applied cognitive and behavioural approaches to the treatment of addiction: a practical treatment guide","author":"Mitcheson","year":"2010"},{"key":"10.1016\/j.cct.2016.12.003_bb0270","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1017\/S1352465801004040","article-title":"The revised cognitive therapy scale (CTS\u2013R): psychometric properties","volume":"29","author":"Blackburn","year":"2001","journal-title":"Behav. Cogn. Psychother."},{"key":"10.1016\/j.cct.2016.12.003_bb0275","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1177\/0962280209105014","article-title":"Mediation and moderation of treatment effects in randomised controlled trials of complex interventions","volume":"19","author":"Emsley","year":"2010","journal-title":"Stat. Methods Med. Res."},{"key":"10.1016\/j.cct.2016.12.003_bb0280","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1207\/s15328007sem1304_1","article-title":"On the merits of orthogonalizing powered and product terms: implications for modeling interactions among latent variables","volume":"13","author":"Little","year":"2006","journal-title":"Struct. Equ. Model."},{"key":"10.1016\/j.cct.2016.12.003_bb0285","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2165\/00019053-199610050-00003","article-title":"practical guide for calculating indirect costs of disease","volume":"10","author":"Koopmanschap","year":"1996","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.cct.2016.12.003_bb0290","series-title":"Revisions made to the multipliers and unit costs of crime used in the Integrated Offender Management Value for Money Toolkit","author":"Home Office","year":"2011"},{"key":"10.1016\/j.cct.2016.12.003_bb0295","series-title":"Analysis of Cost Data in Randomised Trials: An Application of the Non-parametric Bootstrap","first-page":"3219","volume":"19","author":"Barber","year":"2000"},{"key":"10.1016\/j.cct.2016.12.003_bb0300","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1002\/hec.901","article-title":"Calculation of quality adjusted life years in the published literature: a review of methodology and transparency","volume":"13","author":"Richardson","year":"2004","journal-title":"Health Econ."},{"key":"10.1016\/j.cct.2016.12.003_bb0305","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1192\/bjp.187.2.106","article-title":"A guide to cost-effectiveness acceptability curves","volume":"187","author":"Fenwick","year":"2005","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0310","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.psyneuen.2014.03.017","article-title":"Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype","volume":"45","author":"Levran","year":"2014","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.cct.2016.12.003_bb0315","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.euroneuro.2013.05.014","article-title":"Pharmacogenetic randomized trial for cocaine abuse: disulfiram and \u03b11A-adrenoceptor gene variation","volume":"23","author":"Shorter","year":"2013","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.cct.2016.12.003_bb0320","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4088\/JCP.14m09096","article-title":"Initial Response as a Predictor of 12-Week Buprenorphine\u2013Naloxone Treatment Response in a Prescription Opioid\u2013Dependent Population","volume":"76","author":"McDermott","year":"2015","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.cct.2016.12.003_bb0325","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1146\/annurev.med.59.062606.122232","article-title":"Adaptive treatment strategies in chronic disease","volume":"59","author":"Lavori","year":"2008","journal-title":"Annu. Rev. Med."}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714416302737?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714416302737?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T23:57:03Z","timestamp":1536191823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714416302737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":65,"alternative-id":["S1551714416302737"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2016.12.003","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of adjunctive, personalised psychosocial intervention for non-response to opioid agonist treatment: Study protocol for a pragmatic randomised controlled trial","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2016.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}