{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:48:25Z","timestamp":1787240905456,"version":"build-2736575974"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.cct.2021.106325","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T20:34:15Z","timestamp":1614026055000},"page":"106325","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Collaborative care in the treatment of opioid use disorder and mental health conditions in primary care: A clinical study protocol"],"prefix":"10.1016","volume":"103","author":[{"given":"Rebecca Arden","family":"Harris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Mandell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle M.","family":"Kampman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhua","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuleyha","family":"Cidav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna M.","family":"Coviello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Livesey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Lowenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin G.","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"McKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Oslin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney Benjamin","family":"Wolk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hillary R.","family":"Bogner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cct.2021.106325_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00325481.2018.1407618","article-title":"Going beyond prescription pain relievers to understand the opioid epidemic: the role of illicit fentanyl, new psychoactive substances, and street heroin","volume":"130","author":"Pergolizzi","year":"2018","journal-title":"Postgrad. Med."},{"key":"10.1016\/j.cct.2021.106325_bb0010","series-title":"Annual Surveillance Report of Drug-Related Risks and Outcomes \u2013 United States Surveillance Special Report","author":"Centers for Disease Control and Prevention","year":"2019"},{"key":"10.1016\/j.cct.2021.106325_bb0015","series-title":"Deaths of Despair and the Future of Capitalism","author":"Case","year":"2020"},{"key":"10.1016\/j.cct.2021.106325_bb0020","series-title":"Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use","author":"National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division","year":"2017"},{"key":"10.1016\/j.cct.2021.106325_bb0025","series-title":"Drug overdose deaths in the United States, 1999\u20132018. NCHS Data Brief, no 356","author":"Hedegaard","year":"2020"},{"key":"10.1016\/j.cct.2021.106325_bb0030","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.drugalcdep.2018.12.030","article-title":"Co-occurring substance use and mental disorders among adults with opioid use disorder","volume":"197","author":"Jones","year":"2019","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2021.106325_bb0035","series-title":"Medication-Assisted Treatment for Opioid Use Disorder: Proceedings of a Workshop\u2013in Brief","author":"National Academies of Sciences, Engineering, and Medicine","year":"2018"},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0040","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1176\/appi.ajp.2007.06111851","article-title":"A meta-analytic review of psychosocial interventions for substance use disorders","volume":"165","author":"Dutra","year":"2008","journal-title":"Am. J. Psychiatr."},{"issue":"6","key":"10.1016\/j.cct.2021.106325_bb0045","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1377\/hlthaff.2019.01622","article-title":"Buprenorphine treatment by primary care providers, psychiatrists, addiction specialists, and others","volume":"39","author":"Olfson","year":"2020","journal-title":"Health Aff (Millwood)."},{"key":"10.1016\/j.cct.2021.106325_bb0050","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jsat.2018.09.001","article-title":"Risk factors for discontinuation of buprenorphine treatment for opioid use disorders in a multi-state sample of Medicaid enrollees","volume":"95","author":"Samples","year":"2018","journal-title":"J. Subst. Abus. Treat."},{"issue":"3","key":"10.1016\/j.cct.2021.106325_bb0055","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/jama.2019.18913","article-title":"Trends in buprenorphine treatment in the United States, 2009\u20132018","volume":"323","author":"Olfson","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.cct.2021.106325_bb0060","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.drugalcdep.2018.06.006","article-title":"Treatment outcome disparities for opioid users: are there racial and ethnic differences in treatment completion across large US metropolitan areas?","volume":"190","author":"Stahler","year":"2018","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2021.106325_bb0065","series-title":"Strategies for developing treatment programs for people with co-occurring substance abuse and mental disorders. SAMHSA Publication No. 3782","author":"Substance Abuse and Mental Health Services Administration (SAMHSA)","year":"2003"},{"key":"10.1016\/j.cct.2021.106325_bb0070","doi-asserted-by":"crossref","DOI":"10.1177\/2150132720932017","article-title":"Mental health and psychosocial needs of patients being treated for opioid use disorder in a primary care residency clinic","volume":"11","author":"Hooker","year":"2020","journal-title":"J. Prim. Care Community Health"},{"issue":"11","key":"10.1016\/j.cct.2021.106325_bb0075","first-page":"887","article-title":"Population targeting and durability of multimorbidity collaborative care management","volume":"20","author":"Lin","year":"2014","journal-title":"Am J Manag Care"},{"issue":"8","key":"10.1016\/j.cct.2021.106325_bb0080","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s11920-013-0383-2","article-title":"Mental health collaborative care and its role in primary care settings","volume":"15","author":"Goodrich","year":"2013","journal-title":"Curr Psychiatry Rep."},{"issue":"10","key":"10.1016\/j.cct.2021.106325_bb0085","doi-asserted-by":"crossref","first-page":"e0186315","DOI":"10.1371\/journal.pone.0186315","article-title":"Primary care models for treating opioid use disorders: What actually works? A systematic review","volume":"12","author":"Lagisetty","year":"2017","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.cct.2021.106325_bb0090","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1176\/appi.ps.201400047","article-title":"Peer recovery support for individuals with substance use disorders: assessing the evidence","volume":"65","author":"Reif","year":"2014","journal-title":"Psychiatr. Serv."},{"key":"10.1016\/j.cct.2021.106325_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsat.2016.01.003","article-title":"Peer-delivered recovery support services for addictions in the United States: a systematic review","volume":"63","author":"Bassuk","year":"2016","journal-title":"Journal of Substance Abuse Treatment"},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167900","article-title":"A randomized controlled pilot trial of different mobile messaging interventions for problem drinking compared to weekly drink tracking","volume":"12","author":"Muench","year":"2017","journal-title":"PLoS One"},{"issue":"82","key":"10.1016\/j.cct.2021.106325_bb0105","article-title":"Effects of automated smartphone mobile recovery support and telephone continuing care in the treatment of alcohol use disorder: study protocol for a randomized controlled trial","volume":"19","author":"McKay","year":"2018","journal-title":"Trials"},{"key":"10.1016\/j.cct.2021.106325_bb0110","article-title":"Collaborative care for individuals with opioid use disorders and co-occurring mental health conditions: Psychotherapy manual for care managers","author":"DePhilippis","year":"2020","journal-title":"Penn Center for Mental Health"},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0115","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.pec.2013.07.012","article-title":"Motivational interviewing in medical care settings: a systematic review and meta-analysis of randomized controlled trials","volume":"93","author":"Lundahl","year":"2013","journal-title":"Patient Educ. Couns."},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0120","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s13142-013-0248-6","article-title":"Implementing brief cognitive behavioral therapy in primary care: a pilot study","volume":"4","author":"Mignogna","year":"2014","journal-title":"Transl. Behav. Med."},{"key":"10.1016\/j.cct.2021.106325_bb0125","series-title":"Cognitive and Behavioral Theories in Clinical Practice","first-page":"193","article-title":"Behavioral activation therapy","author":"Martell","year":"2010"},{"issue":"3","key":"10.1016\/j.cct.2021.106325_bb0130","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1037\/fsh0000333","article-title":"Behavioral medicine interventions for adult primary care settings: a review","volume":"36","author":"Funderburk","year":"2018","journal-title":"Fam Syst Health."},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0135","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.pop.2016.01.006","article-title":"Behavioral health in prevention and chronic illness management: motivational interviewing","volume":"43","author":"Tuccero","year":"2016","journal-title":"Prim Care."},{"issue":"12","key":"10.1016\/j.cct.2021.106325_bb0140","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s11920-019-1117-x","article-title":"Psychological treatment of depression in primary care: recent developments","volume":"21","author":"Cuijpers","year":"2019","journal-title":"Curr Psychiatry Rep."},{"issue":"1","key":"10.1016\/j.cct.2021.106325_bb0145","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1370\/afm.1719","article-title":"Effectiveness of psychological treatments for depressive disorders in primary care: systematic review and meta-analysis","volume":"13","author":"Linde","year":"2015","journal-title":"Ann. Fam. Med."},{"issue":"3","key":"10.1016\/j.cct.2021.106325_bb0150","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jsat.2012.07.013","article-title":"Development and initial evaluation of the brief addiction monitor (BAM)","volume":"44","author":"Cacciola","year":"2013","journal-title":"J. Subst. Abus. Treat."},{"key":"10.1016\/j.cct.2021.106325_bb0155","series-title":"Foundations for Integrated Care: Behavioral Health Solutions for Primary Care","volume":"vol. 1-6","author":"Oslin","year":"2013"},{"issue":"2","key":"10.1016\/j.cct.2021.106325_bb0160","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/ADM.0000000000000193","article-title":"A systematic review on the use of psychosocial interventions in conjunction with medications for the treatment of opioid addiction","volume":"10","author":"Dugosh","year":"2016","journal-title":"J. Addict. Med."},{"issue":"5","key":"10.1016\/j.cct.2021.106325_bb0165","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1080\/00952990.2020.1780602","article-title":"Cognitive-behavioral therapy and buprenorphine for opioid use disorder: a systematic review and meta-analysis of randomized controlled trials","volume":"46","author":"Gregory","year":"2020","journal-title":"Am J Drug Alcohol Abuse."},{"issue":"4","key":"10.1016\/j.cct.2021.106325_bb0170","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.2105\/AJPH.2015.302987","article-title":"Effects of community-based health worker interventions to improve chronic disease management and care among vulnerable populations: a systematic review","volume":"106","author":"Kim","year":"2016","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.cct.2021.106325_bb0175","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cct.2016.12.009","article-title":"A randomized controlled trial of a community health worker intervention in a population of patients with multiple chronic diseases: study design and protocol","volume":"53","author":"Kangovi","year":"2017","journal-title":"Contemp Clin Trials."},{"issue":"10","key":"10.1016\/j.cct.2021.106325_bb0180","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.2105\/AJPH.2017.303985","article-title":"Community health worker support for disadvantaged patients with multiple chronic diseases: a randomized clinical trial","volume":"107","author":"Kangovi","year":"2017","journal-title":"Am. J. Public Health"},{"issue":"3\u20134","key":"10.1016\/j.cct.2021.106325_bb0185","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1007\/s10464-009-9234-z","article-title":"Changing drug users\u2019 risk environments: peer health advocates as multi-level community change agents","volume":"43","author":"Weeks","year":"2009","journal-title":"Am. J. Community Psychol."},{"key":"10.1016\/j.cct.2021.106325_bb0190","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1186\/1471-2458-13-847","article-title":"Effectiveness of community health workers delivering preventive interventions for maternal and child health in low- and middle-income countries: a systematic review","volume":"13","author":"Gilmore","year":"2013","journal-title":"BMC Public Health"},{"key":"10.1016\/j.cct.2021.106325_bb0195","doi-asserted-by":"crossref","first-page":"108248","DOI":"10.1016\/j.jsat.2020.108248","article-title":"Peer recovery coaches in general medical settings: Changes in utilization, treatment engagement, and opioid use","volume":"122","author":"Magidson","year":"2021","journal-title":"J Subst Abuse Treat."},{"key":"10.1016\/j.cct.2021.106325_bb0200","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.drugalcdep.2004.07.006","article-title":"Brief motivational intervention at a clinic visit reduces cocaine and heroine use","volume":"77","author":"Bernstein","year":"2005","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.cct.2021.106325_bb0205","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.2975\/30.3.2007.207.213","article-title":"Peer support for persons with co-occurring disorders and community tenure: a survival analysis","volume":"30","author":"Min","year":"2007","journal-title":"Psychiatr Rehabil J."},{"key":"10.1016\/j.cct.2021.106325_bb0210","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s11606-018-4807-x","article-title":"Effect of integrating substance use disorder into primary care on inpatient and emergency department utilization","volume":"34","author":"Wakeman","year":"2019","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.cct.2021.106325_bb0215","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1176\/ps.2007.58.7.955","article-title":"A peer-support, group intervention to reduce substance use and criminality among persons with severe mental illness","volume":"58","author":"Rowe","year":"2007","journal-title":"Psychiatr. Serv."},{"issue":"9","key":"10.1016\/j.cct.2021.106325_bb0220","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J. Gen. Intern. Med."},{"issue":"10","key":"10.1016\/j.cct.2021.106325_bb0225","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"issue":"8","key":"10.1016\/j.cct.2021.106325_bb0230","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0005-7967(96)00033-2","article-title":"Psychometric properties of the PTSD Checklist (PCL)","volume":"34","author":"Blanchard","year":"1996","journal-title":"Behav. Res. Ther."},{"issue":"5","key":"10.1016\/j.cct.2021.106325_bb0235","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J. Chronic Dis."},{"key":"10.1016\/j.cct.2021.106325_bb0240","series-title":"Categorical Data Analysis","author":"Agresti","year":"2002"},{"key":"10.1016\/j.cct.2021.106325_bb0245","series-title":"Applied Longitudinal Analysis","author":"Fitzmaurice","year":"2011"},{"key":"10.1016\/j.cct.2021.106325_bb0250","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cmpb.2018.06.014","article-title":"Measuring the impact of nonignorable Missingness using the R package isni","volume":"164","author":"Xie","year":"2018","journal-title":"Comput. Methods Prog. Biomed."}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714421000616?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714421000616?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:52:59Z","timestamp":1761555179000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714421000616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":50,"alternative-id":["S1551714421000616"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2021.106325","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Collaborative care in the treatment of opioid use disorder and mental health conditions in primary care: A clinical study protocol","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2021.106325","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106325"}}