{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:19:18Z","timestamp":1792793958378,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.cct.2021.106367","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T02:02:04Z","timestamp":1616551324000},"page":"106367","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["SACRED: Effect of simvastatin on hepatic decompensation and death in subjects with high-risk compensated cirrhosis: Statins and Cirrhosis: Reducing Events of Decompensation"],"prefix":"10.1016","volume":"104","author":[{"given":"David E.","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajni","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guadalupe","family":"Garcia-Tsao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Albrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse","family":"Aytaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyorgy","family":"Baffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmohan","family":"Bajaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben","family":"Hernaez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristel","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Ioannou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fasiha","family":"Kanwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Monto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Pandya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Schaubel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar H.","family":"Taddei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cct.2021.106367_bb0005","article-title":"Healthcare costs related to treatment of hepatocellular carcinoma among veterans with cirrhosis in the United States","author":"Kaplan","year":"2017","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.cct.2021.106367_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.cgh.2015.07.010","article-title":"Development and performance of an algorithm to estimate the child-turcotte-pugh score from a national electronic healthcare database","author":"Kaplan","year":"2015","journal-title":"Clin. Gastroenterol. Hepatol."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0015","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2015.07.056","article-title":"Trends in burden of cirrhosis and hepatocellular carcinoma by underlying liver disease in US veterans, 2001-2013","volume":"149","author":"Beste","year":"2015","journal-title":"Gastroenterology."},{"issue":"3","key":"10.1016\/j.cct.2021.106367_bb0020","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.cgh.2005.12.007","article-title":"The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence","volume":"4","author":"El-Serag","year":"2006","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.cct.2021.106367_bb0025","doi-asserted-by":"crossref","DOI":"10.1111\/liv.13151","article-title":"The clinical course of alcoholic cirrhosis: development of comorbid diseases. A Danish nationwide cohort study","author":"Jepsen","year":"2016","journal-title":"Liver Int."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0030","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1007\/s10620-015-4000-6","article-title":"Statins are underutilized in patients with nonalcoholic fatty liver disease and dyslipidemia","volume":"61","author":"Blais","year":"2016","journal-title":"Dig. Dis. Sci."},{"issue":"4","key":"10.1016\/j.cct.2021.106367_bb0035","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/1538574410362922","article-title":"Basic science review: statin therapy--part I: the pleiotropic effects of statins in cardiovascular disease","volume":"44","author":"Sadowitz","year":"2010","journal-title":"Vasc. Endovasc. Surg."},{"issue":"8","key":"10.1016\/j.cct.2021.106367_bb0040","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1093\/ndt\/gfh859","article-title":"Simvastatin attenuates renal inflammation, tubular transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction","volume":"20","author":"Vieira","year":"2005","journal-title":"Nephrol. Dial. Transplant."},{"issue":"3","key":"10.1016\/j.cct.2021.106367_bb0045","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/hr.2010.243","article-title":"Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading","volume":"34","author":"Yamamoto","year":"2011","journal-title":"Hypertens. Res."},{"issue":"11","key":"10.1016\/j.cct.2021.106367_bb0050","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1007\/s10620-008-0241-y","article-title":"Beneficial effects of fluvastatin on liver microcirculation and regeneration after massive hepatectomy in rats","volume":"53","author":"Tokunaga","year":"2008","journal-title":"Dig. Dis. Sci."},{"issue":"9","key":"10.1016\/j.cct.2021.106367_bb0055","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1111\/1440-1681.12446","article-title":"Antifibrotic effect of AT-1 blocker and statin in rats with hepatic fibrosis","volume":"42","author":"El-Ashmawy","year":"2015","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0060","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.jhep.2007.01.020","article-title":"Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats","volume":"46","author":"Abraldes","year":"2007","journal-title":"J. Hepatol."},{"issue":"2","key":"10.1016\/j.cct.2021.106367_bb0065","doi-asserted-by":"crossref","first-page":"G147","DOI":"10.1152\/ajpgi.00462.2007","article-title":"Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver","volume":"296","author":"Moreno","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"11","key":"10.1016\/j.cct.2021.106367_bb0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0080588","article-title":"Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment","volume":"8","author":"Busnelli","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.cct.2021.106367_bb0075","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/hep.26127","article-title":"Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction","volume":"57","author":"La Mura","year":"2013","journal-title":"Hepatology."},{"issue":"12","key":"10.1016\/j.cct.2021.106367_bb0080","first-page":"1167","article-title":"Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway","volume":"48","author":"Zhang","year":"2010","journal-title":"Indian J. Exp. Biol."},{"issue":"5","key":"10.1016\/j.cct.2021.106367_bb0085","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1053\/j.gastro.2009.01.053","article-title":"Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes","volume":"136","author":"El-Serag","year":"2009","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0090","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1053\/j.gastro.2019.01.026","article-title":"Effects of hypercholesterolemia and statin exposure on survival in a large national cohort of patients with cirrhosis","volume":"156","author":"Kaplan","year":"2019","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0095","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/apt.12430","article-title":"Statin use and infections in veterans with cirrhosis","volume":"38","author":"Motzkus-Feagans","year":"2013","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"2","key":"10.1016\/j.cct.2021.106367_bb0100","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1053\/j.gastro.2015.10.007","article-title":"Statins are associated with a decreased risk of decompensation and death in veterans with hepatitis C-related compensated cirrhosis","volume":"150","author":"Mohanty","year":"2016","journal-title":"Gastroenterology."},{"issue":"5","key":"10.1016\/j.cct.2021.106367_bb0105","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1053\/j.gastro.2016.01.004","article-title":"Addition of simvastatin to standard therapy for the prevention of variceal rebleeding does not reduce Rebleeding but increases survival in patients with cirrhosis","volume":"150","author":"Abraldes","year":"2016","journal-title":"Gastroenterology"},{"issue":"8","key":"10.1016\/j.cct.2021.106367_bb0110","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1007\/s10620-014-3179-2","article-title":"Statin use in patients with cirrhosis: a retrospective cohort study","volume":"59","author":"Kumar","year":"2014","journal-title":"Dig. Dis. Sci."},{"issue":"3","key":"10.1016\/j.cct.2021.106367_bb0115","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/hep.29172","article-title":"Statins decrease the risk of decompensation in hepatitis B virus- and hepatitis C virus-related cirrhosis: a population-based study","volume":"66","author":"Chang","year":"2017","journal-title":"Hepatology."},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0120","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/bcpt.12844","article-title":"Statins and angiotensin-converting enzyme inhibitors are associated with reduced mortality and morbidity in chronic liver disease","volume":"122","author":"Stokkeland","year":"2018","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"3","key":"10.1016\/j.cct.2021.106367_bb0125","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1053\/j.gastro.2003.12.007","article-title":"Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis","volume":"126","author":"Zafra","year":"2004","journal-title":"Gastroenterology."},{"issue":"5","key":"10.1016\/j.cct.2021.106367_bb0130","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1053\/j.gastro.2009.01.043","article-title":"Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial","volume":"136","author":"Abraldes","year":"2009","journal-title":"Gastroenterology."},{"issue":"10","key":"10.1016\/j.cct.2021.106367_bb0135","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.cgh.2017.04.039","article-title":"Statin use and risk of cirrhosis and related complications in patients with chronic liver diseases: a systematic review and meta-analysis","volume":"15","author":"Kim","year":"2017","journal-title":"Clin. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0140","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S2468-1253(19)30320-6","article-title":"Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial","volume":"5","author":"Pose","year":"2020","journal-title":"Lancet Gastroenterol. Hepatol."},{"issue":"8","key":"10.1016\/j.cct.2021.106367_bb0145","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1056\/NEJMoa0801936","article-title":"SLCO1B1 variants and statin-induced myopathy\u2014a genomewide study","volume":"359","author":"Group SC","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"17","key":"10.1016\/j.cct.2021.106367_bb0150","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.jacc.2009.04.053","article-title":"The SLCO1B1*5 genetic variant is associated with statin-induced side effects","volume":"54","author":"Voora","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0155","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/cpt.887","article-title":"Genetic and clinical factors are associated with statin-related myotoxicity of moderate severity: a case-control study","volume":"104","author":"Bakar","year":"2018","journal-title":"Clin. Pharmacol. Ther."},{"issue":"9","key":"10.1016\/j.cct.2021.106367_bb0160","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1007\/s00228-018-2482-9","article-title":"A comprehensive review and meta-analysis of risk factors for statin-induced myopathy","volume":"74","author":"Nguyen","year":"2018","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1016\/j.cct.2021.106367_bb0165","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/1471-2350-12-136","article-title":"SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group","volume":"12","author":"Santos","year":"2011","journal-title":"BMC Med. Genet."},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0170","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/hep.28906","article-title":"Portal hypertensive bleeding in cirrhosis: risk stratification, diagnosis, and management: 2016 practice guidance by the American association for the study of liver diseases","volume":"65","author":"Garcia-Tsao","year":"2017","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.cct.2021.106367_bb0175","first-page":"481","article-title":"Genetic determinants of statin-associated myopathy","volume":"5","author":"Molokhia","year":"2008","journal-title":"Perinat. Med."},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0180","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1055\/s-0036-1597891","article-title":"The design of clinical trials in portal hypertension","volume":"37","author":"Abraldes","year":"2017","journal-title":"Semin. Liver Dis."},{"issue":"2","key":"10.1016\/j.cct.2021.106367_bb0185","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1053\/j.gastro.2007.05.024","article-title":"Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis","volume":"133","author":"Ripoll","year":"2007","journal-title":"Gastroenterology."},{"issue":"21","key":"10.1016\/j.cct.2021.106367_bb0190","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1056\/NEJMoa044456","article-title":"Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis","volume":"353","author":"Groszmann","year":"2005","journal-title":"N. Engl. J. Med."},{"issue":"10","key":"10.1016\/j.cct.2021.106367_bb0195","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1111\/apt.12721","article-title":"Competing risks and prognostic stages of cirrhosis: a 25-year inception cohort study of 494 patients","volume":"39","author":"D\u2019Amico","year":"2014","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0200","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1002\/hep.29363","article-title":"Expanding the Baveno VI criteria for the screening of varices in patients with compensated advanced chronic liver disease","volume":"66","author":"Augustin","year":"2017","journal-title":"Hepatology."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0205","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1002\/hep.28824","article-title":"Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: the \u201cAnticipate\u201d study","volume":"64","author":"Abraldes","year":"2016","journal-title":"Hepatology."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0210","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1053\/j.gastro.2017.03.016","article-title":"American Gastroenterological Association Institute technical review on the role of elastography in chronic liver diseases","volume":"152","author":"Singh","year":"2017","journal-title":"Gastroenterology"},{"issue":"25 Pt B","key":"10.1016\/j.cct.2021.106367_bb0215","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1016\/j.jacc.2013.11.002","article-title":"2013 ACC\/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines","volume":"63","author":"Stone","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"issue":"4","key":"10.1016\/j.cct.2021.106367_bb0220","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1111\/j.0006-341X.2001.01030.x","article-title":"Causal inference on the difference of the restricted mean lifetime between two groups","volume":"57","author":"Chen","year":"2001","journal-title":"Biometrics."},{"issue":"3 Suppl","key":"10.1016\/j.cct.2021.106367_bb0230","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.jacl.2014.03.004","article-title":"The National Lipid Association\u2019s muscle safety expert P. an assessment by the statin muscle safety task force: 2014 update","volume":"8","author":"Rosenson","year":"2014","journal-title":"J. Clin. Lipidol."},{"issue":"6","key":"10.1016\/j.cct.2021.106367_bb0235","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1053\/j.gastro.2016.10.010","article-title":"Drug-induced liver injury in patients with preexisting chronic liver disease in drug development: how to identify and manage?","volume":"151","author":"Chalasani","year":"2016","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.cct.2021.106367_bb0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/bjc.1977.1","article-title":"Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples","volume":"35","author":"Peto","year":"1977","journal-title":"Br. J. Cancer"},{"issue":"4","key":"10.1016\/j.cct.2021.106367_bb0245","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.cct.2007.11.005","article-title":"Bayesian design and conduct of phase II single-arm clinical trials with binary outcomes: a tutorial","volume":"29","author":"Zohar","year":"2008","journal-title":"Contemp. Clin. Trials"},{"issue":"8","key":"10.1016\/j.cct.2021.106367_bb0250","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1053\/j.gastro.2018.03.022","article-title":"Baseline factors associated with improvements in decompensated cirrhosis after direct-acting antiviral therapy for hepatitis C virus infection","volume":"154","author":"El-Sherif","year":"2018","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1016\/j.cct.2021.106367_bb0255","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1053\/j.gastro.2017.06.012","article-title":"Risk of hepatocellular cancer in HCV patients treated with direct-acting antiviral agents","volume":"153","author":"Kanwal","year":"2017","journal-title":"Gastroenterology"}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714421001038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714421001038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:53:00Z","timestamp":1761555180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714421001038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":50,"alternative-id":["S1551714421001038"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2021.106367","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SACRED: Effect of simvastatin on hepatic decompensation and death in subjects with high-risk compensated cirrhosis: Statins and Cirrhosis: Reducing Events of Decompensation","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2021.106367","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106367"}}