{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T13:47:21Z","timestamp":1770040041510,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100014756","name":"Hexal AG","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014756","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.cct.2022.106685","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T18:33:53Z","timestamp":1642617233000},"page":"106685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Influence of a 12-month supervised, intensive resistance, aerobic and impact exercise intervention on muscle strength in prostate cancer patients undergoing anti-hormone therapy: Study protocol for the randomized, controlled Burgdorf study"],"prefix":"10.1016","volume":"114","author":[{"given":"N.","family":"Reimer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Hafke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Wrensch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Horst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Bloch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kirchhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.-L.","family":"Kluck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.T.","family":"Baumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cct.2022.106685_bb0005","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.euo.2018.12.004","article-title":"Patient-reported outcomes following treatment of localised prostate cancer and their association with regret about treatment choices","volume":"3","author":"van Stam","year":"2020","journal-title":"Eur. Urol. Oncol."},{"issue":"1","key":"10.1016\/j.cct.2022.106685_bb0010","article-title":"ADT risks and side effects in advanced prostate cancer: cardiovascular and acute renal injury","volume":"29","author":"Crawford","year":"2015","journal-title":"Oncology (Williston Park)"},{"issue":"5","key":"10.1016\/j.cct.2022.106685_bb0015","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.eururo.2014.07.010","article-title":"Adverse effects of androgen deprivation therapy and strategies to mitigate them","volume":"67","author":"Nguyen","year":"2015","journal-title":"Eur. Urol."},{"issue":"6","key":"10.1016\/j.cct.2022.106685_bb0020","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1046\/j.1365-2265.2002.01551.x","article-title":"Long-term effects of androgen deprivation therapy in prostate cancer patients","volume":"56","author":"Basaria","year":"2002","journal-title":"Clin. Endocrinol."},{"issue":"1","key":"10.1016\/j.cct.2022.106685_bb0025","first-page":"133","article-title":"Sexuality and exercise in men undergoing androgen deprivation therapy for prostate cancer","volume":"23","author":"Hamilton","year":"2015","journal-title":"Support Care Cancer"},{"issue":"9","key":"10.1016\/j.cct.2022.106685_bb0030","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1111\/j.1743-6109.2010.01902.x","article-title":"ADT survivorship working group: androgen deprivation therapy for prostate cancer: recommendations to improve patient and partner quality of life","volume":"7","author":"Elliott","year":"2010","journal-title":"J. Sex. Med."},{"issue":"1","key":"10.1016\/j.cct.2022.106685_bb0035","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1464-410X.2008.07539.x","article-title":"Changes in muscle, fat and bone mass after 36 weeks of maximal androgen blockage for prostate cancer","volume":"102","author":"Galv\u00e3o","year":"2008","journal-title":"BJU Int."},{"issue":"27","key":"10.1016\/j.cct.2022.106685_bb0040","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000007368","article-title":"Exercise overcome adverse effects among prostate cancer patients receiving androgen deprivation therapy: an update meta-analysis","volume":"96","author":"Yunfeng","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0045","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.urolonc.2018.10.008","article-title":"Exercise medicine for the management of androgen deprivation therapy-related side effects in prostate cancer","volume":"38","author":"Cormie","year":"2020","journal-title":"Urol. Oncol."},{"issue":"4","key":"10.1016\/j.cct.2022.106685_bb0055","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1188\/15.ONF.348-356","article-title":"Resistance exercise reduces body fat and insulin during androgen-deprivation therapy for prostate Cancer","volume":"42","author":"Winters-Stone","year":"2015","journal-title":"Oncol. Nurs. Forum"},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0060","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.eururo.2017.02.019","article-title":"Effects of different exercise modalities on fatigue in prostate Cancer patients undergoing androgen deprivation therapy: a year-long randomised controlled trial","volume":"72","author":"Taaffe","year":"2017","journal-title":"Eur. Urol."},{"issue":"4","key":"10.1016\/j.cct.2022.106685_bb0065","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1249\/MSS.0000000000001831","article-title":"Exercise mode specificity for preserving spine and hip bone mineral density in prostate Cancer patients","volume":"51","author":"Newton","year":"2019","journal-title":"Med. Sci. Sports Exerc."},{"issue":"8","key":"10.1016\/j.cct.2022.106685_bb0070","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1249\/MSS.0000000000000265","article-title":"Skeletal response to resistance and impact training in prostate cancer survivors","volume":"46","author":"Winters-Stone","year":"2014","journal-title":"Med. Sci. Sports Exerc."},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0075","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1136\/bjsm.30.2.156","article-title":"Eccentric and concentric isokinetic knee flexion and extension: a reliability study using the Cybex 6000 dynamometer","volume":"30","author":"Li","year":"1996","journal-title":"Br. J. Sports Med."},{"issue":"5","key":"10.1016\/j.cct.2022.106685_bb0080","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"J. Natl. Cancer Inst."},{"issue":"16","key":"10.1016\/j.cct.2022.106685_bb0085","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1016\/j.ejca.2008.07.030","article-title":"An international field study of the EORTC QLQ-PR25: a questionnaire for assessing the health-related quality of life of patients with prostate cancer","volume":"44","author":"van Andel","year":"2008","journal-title":"Eur. J. Cancer"},{"issue":"5","key":"10.1016\/j.cct.2022.106685_bb0090","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1177\/1534735415583552","article-title":"Effect of a 15-month supervised exercise program on physical and psychological outcomes in prostate Cancer patients following prostatectomy: the ProRehab study","volume":"14","author":"Zopf","year":"2015","journal-title":"Integr Cancer Ther"},{"issue":"3","key":"10.1016\/j.cct.2022.106685_bb0095","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0022-3999(94)00125-O","article-title":"The multidimensional fatigue inventory (MFI) psychometric qualities of an instrument to assess fatigue","volume":"39","author":"Smets","year":"1995","journal-title":"J. Psychosom. Res."},{"issue":"6","key":"10.1016\/j.cct.2022.106685_bb0100","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.clnu.2004.09.012","article-title":"ESPEN: bioelectrical impedance analysis-part II: utilization in clinical practice","volume":"23","author":"Kyle","year":"2004","journal-title":"Clin. Nutr."},{"issue":"6","key":"10.1016\/j.cct.2022.106685_bb0105","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/ejcn.2013.266","article-title":"Multi-frequency bioelectrical impedance analysis for assessing fat mann and fat-free mass in stroke or transient ischaemic attack patients","volume":"68","author":"Kafri","year":"2014","journal-title":"Eur. J. Clin. Nutr."},{"issue":"6","key":"10.1016\/j.cct.2022.106685_bb0110","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0090-4295(97)00238-0","article-title":"The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction","volume":"49","author":"Rosen","year":"1997","journal-title":"Urology"},{"key":"10.1016\/j.cct.2022.106685_bb0115","unstructured":"FACIT.org. FACT-BP. Quality of Life measurement in patients with bone pain. English (Universal), Copyright 2002, 27.08.2004 https:\/\/www.google.com\/url?sa=t&rct=j&q=&esrc=s&source=web&cd=3&ved=2ahUKEwjt85y1vpnnAhUJJFAKHbz_AMcQFjACegQIBhAB&url=https%3A%2F%2Fwww.facit.org%2FLiteratureRetrieve.aspx%3FID%3D42373&usg=AOvVaw3Kx3arR--MkVyIHcEBQtPA. (accessed 22 September 2019)."},{"key":"10.1016\/j.cct.2022.106685_bb0120","author":"World Health Organization"},{"key":"10.1016\/j.cct.2022.106685_bb0125","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/1471-2407-13-272","article-title":"Influence of a six month endurance exercise program on the immune function of prostate cancer patients undergoing antiandrogen- or chemotherapy: design and rationale of the ProImmun study","volume":"13","author":"Zimmer","year":"2013","journal-title":"BMC Cancer"},{"issue":"12","key":"10.1016\/j.cct.2022.106685_bb0130","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1249\/01.mss.0000233803.48691.8b","article-title":"Resistance training and reduction of treatment side effects in prostate cancer patients","volume":"38","author":"Galv\u00e3o","year":"2006","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.cct.2022.106685_bb0135","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/1471-2407-12-312","article-title":"Implementation and scientific evaluation of rehabilitative sports groups for prostate cancer patients: study protocol of the ProRehab study","volume":"12","author":"Zopf","year":"2012","journal-title":"BMC Cancer"},{"issue":"4","key":"10.1016\/j.cct.2022.106685_bb0140","first-page":"271","article-title":"Cancer treatment and survivorship statistics, 2016","volume":"66","author":"Miller","year":"2016","journal-title":"CA Cancer J. Clin."},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0145","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1200\/JCO.2009.23.2488","article-title":"Combined resistance and aerobic exercise program reverses muscle loss in men undergoing androgen suppression therapy for prostate cancer without bone metastases: a randomized controlled trial","volume":"28","author":"Galv\u00e3o","year":"2010","journal-title":"J. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0150","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/bju.12646","article-title":"Can supervised exercise prevent treatment toxicity in opatients with prostate cancer initiating androgen-deprivation therapy: a randomized controlled trial","volume":"115","author":"Cormie","year":"2015","journal-title":"BJU Int."},{"issue":"8","key":"10.1016\/j.cct.2022.106685_bb0155","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1249\/MSS.0000000000001277","article-title":"Exercise improves VO2max and body composition in androgen deprivation therapy-treated prostate Cancer patients","volume":"49","author":"Wall","year":"2017","journal-title":"Med. Sci. Sports Exerc."},{"issue":"10","key":"10.1016\/j.cct.2022.106685_bb0160","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.6004\/jnccn.2019.7311","article-title":"Responsiveness to resistance-based multimodal exercise among men with prostate Cancer receiving androgen deprivation therapy","volume":"17","author":"Taaffe","year":"2019","journal-title":"J. Natl. Compr. Cancer Netw."},{"issue":"2","key":"10.1016\/j.cct.2022.106685_bb0165","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/bju.14505","article-title":"Immediate versus delayed exercise in men initiating androgen deprivation: effects on bone density and soft tissue composition","volume":"123","author":"Taaffe","year":"2019","journal-title":"BJU Int."},{"issue":"Suppl. 1","key":"10.1016\/j.cct.2022.106685_bb0170","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/sms.13242","article-title":"Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer","volume":"28","author":"Uth","year":"2018","journal-title":"Scand. J. Med. Sci. Sports"}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714422000118?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714422000118?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:54:05Z","timestamp":1761555245000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714422000118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":33,"alternative-id":["S1551714422000118"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2022.106685","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of a 12-month supervised, intensive resistance, aerobic and impact exercise intervention on muscle strength in prostate cancer patients undergoing anti-hormone therapy: Study protocol for the randomized, controlled Burgdorf study","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2022.106685","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106685"}}